|
1.
|
|
21 p, 1.2 MB |
PAR2 Pepducin-Based Suppression of Inflammation and Itch in Atopic Dermatitis Models
/
Barr, T.P. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ;
Garzia, C. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ;
Guha, S. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ;
Fletcher, E.K. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ;
Nguyen, N. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ;
Wieschhaus, A.J. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ;
Ferrer i Caubet, Lluís (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Covic, L. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ;
Kuliopulos, A. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research)
PAR2 has been proposed to contribute to lesion formation and intense itch in atopic dermatitis. Here, we tested the ability of a cell-penetrating pepducin, PZ-235, to mitigate the potentially deleterious effects of PAR2 in models of atopic dermatitis. [...]
2019 -  10.1016/j.jid.2018.08.019
The Journal of investigative dermatology, Vol. 139 Núm. 2 (february 2019) , p. 412-421
|
|
|
2.
|
|
16 p, 715.0 KB |
A somatic mutation in moesin drives progression into acute myeloid leukemia
/
Yuan, Ouyang. (Lund University) ;
Ugale, Amol. (The University of Vienna) ;
de Marchi, Tommaso (Lund University) ;
Anthonydhason, Vimala (Sahlgrenska Center for Cancer Research. University of Gothenburg) ;
Konturek-Ciesla, Anna (Lund University) ;
Wan, Haixia (Lund University) ;
Eldeeb, Mohamed (Lund University) ;
Drabe, Caroline (Lund University) ;
Jassinskaja, Maria (University of York) ;
Hansson, Jenny (Lund University) ;
Hidalgo, Isabel (Lund University) ;
Velasco-Hernández, Talia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Cammenga, Jörg (Lund University) ;
Magee, Jeffrey A. (Washington University School of Medicine) ;
Niméus, Emma (Skåne University Hospital (Suècia)) ;
Bryder, David (Lund University) ;
Universitat Autònoma de Barcelona
2022 - 10.1126/sciadv.abm9987
Science advances, Vol. 8 Núm. 16 (april 2022) , p. eabm9987
|
|
|
3.
|
|
11 p, 1.1 MB |
The Effects of Maternal Metformin Treatment on Late Prenatal and Early Postnatal Development of the Offspring Are Modulated by Sex
/
García-Contreras, Consolación (SGIT-INIA) ;
Vázquez-Gómez, Marta (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Pesántez-Pacheco, José Luis (Universidad de Cuenca. Faculty of Agricultural Sciences, School of Veterinary Medicine and Zootechnics) ;
Heras-Molina, Ana (SGIT-INIA) ;
Encinas, Teresa (Universidad Complutense de Madrid. Facultad de Veterinaria) ;
Astiz, Susana (SGIT-INIA) ;
Gonzalez-Bulnes, Antonio (Universidad Complutense de Madrid. Facultad de Veterinaria)
Metformin is currently used to improve pregnancy outcome in women affected by polycystic ovary syndrome (PCOS) or diabetes. However, metformin may also be useful in pregnancies at risk of intrauterine growth restriction (IUGR) since it improves placental efficiency and the fetuses' developmental competence. [...]
2020 - 10.3390/ph13110363
Pharmaceuticals, Vol. 13 (november 2020)
|
|
|
4.
|
|
34 p, 4.2 MB |
Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals
/
Taglialegna, Agustina (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Agrobiotecnología) ;
Navarro, Susanna (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Garnett, James A. (Queen Mary University of London. School of Biological and Chemical Sciences) ;
Matthews, Steve (Imperial College London. Department of Life Sciences) ;
Penades, José R. (University of Glasgow. College of Medical, Veterinary and Life Sciences) ;
Lasa, Iñigo (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Agrobiotecnología) ;
Valle, Jaione (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Agrobiotecnología)
Biofilms are communities of bacteria that grow encased in an extracellular matrix that often contains proteins. The spatial organization and the molecular interactions between matrix scaffold proteins remain in most cases largely unknown. [...]
2016 - 10.1371/journal.ppat.1005711
PLOS pathogens, Vol. 12, issue 6 (June 2016) , p. e1005711
|
|
|
5.
|
|
37 p, 10.2 MB |
Cryptococcus neoformans can form titan-like cells in vitro in response to multiple signals
/
Trevijano-Contador, Núria (Centro Nacional de Microbiología (Espanya)) ;
Oliveira, Haroldo César de (Universidade Estadual Paulista (UNESP). Departamento de Análises Clínicas) ;
García-Rodas, Rocío (Centro Nacional de Microbiología (Espanya)) ;
Rossi, Suélen Andreida (Centro Nacional de Microbiología (Espanya)) ;
Llorente, Irene (Centro Nacional de Microbiología (Espanya)) ;
Zaballos, Ángel (Instituto de Salud Carlos III) ;
Janbon, Guilhem (Institut Pasteur. Département de Mycologie) ;
Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Zaragoza, Óscar (Centro Nacional de Microbiología (Espanya)) ;
Universitat Autònoma de Barcelona.
Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
Cryptococcus neoformans is an encapsulated pathogenic yeast that can change the size of the cells during infection. In particular, this process can occur by enlarging the size of the capsule without modifying the size of the cell body, or by increasing the diameter of the cell body, which is normally accompanied by an increase of the capsule too. [...]
2018 - 10.1371/journal.ppat.1007007
PLOS pathogens, Vol. 14 issue 5 (2018) , art. e1007007
|
|
|
6.
|
|
|
7.
|
|
31 p, 4.4 MB |
The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility
/
Gomez Hernández, Laura (Centro de Investigación del Cáncer) ;
Felipe Medina, Natalia (Centro de Investigación del Cáncer) ;
Bejarano Condezo, Yazmine (Centro de Investigación del Cáncer) ;
Garcia Valiente, Rodrigo (Centro de Investigación del Cáncer) ;
Ramos, Isabel (Centro de Investigación del Cáncer) ;
Suja, José Ángel (Universidad Autónoma de Madrid. Unidad de Biologia Celular) ;
Barbero, José Luis (Centro de Investigaciones Biológicas (Madrid)) ;
Roig, Ignasi (Ignasi) (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Sanchez Martin, Manuel. (Universidad de Salamanca. Departamento de Medicina) ;
De Rooij, Dirk G.. (Utrecht University. Departent of Biology) ;
Llano, Elena (Universidad de Salamanca. Departamento de Fisiología y Farmacología) ;
Martín Pendas, Alberto (Centro de Investigación del Cáncer)
The ubiquitin proteasome system regulates meiotic recombination in yeast through its association with the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [...]
2019 - 10.1371/journal.pgen.1008316
PLoS Genetics, Vol. 15, issue 8 (August 2019) , e1008316
|
|
|
8.
|
|
14 p, 3.9 MB |
Systems analysis reveals complex biological processes during virus infection fate decisions
/
Argilaguet, Jordi (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Pedragosa, Mireia (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Esteve-Codina, Anna (Universitat Pompeu Fabra) ;
Riera, G. (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Vidal Barba, Enric (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Peligero-Cruz, C. (Weizmann Institute of Science (Israel). Department of Immunology) ;
Casella, Valentina (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Andreu Martínez, David (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Kaisho, T. (Osaka University. Laboratory for Immune Regulation. World Premier International Research Center Initiative.) ;
Bocharov, G. (Sechenov First Moscow State Medical University) ;
Ludewig, B. (Institute for Immunobiology.) ;
Heath, Simon (Universitat Pompeu Fabra) ;
Meyerhans, A. (Institució Catalana de Recerca i Estudis Avançats)
The processes and mechanisms of virus infection fate decisions that are the result of a dynamic virus-immune system interaction with either an efficient effector response and virus elimination or an alleviated immune response and chronic infection are poorly understood. [...]
2019 - 10.1101/gr.241372.118
Genome research, Vol. 29 Núm. 6 (2019) , p. 907-919
|
|
|
9.
|
|
5 p, 818.2 KB |
First evidence for an association between joint hypermobility and excitability in a non-human species, the domestic dog
/
Bowen, Jonathan (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fatjó i Ríos, Jaume (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Serpell, J. A. (University of Pennsylvania. School of Veterinary Medicine) ;
Bulbena-Cabre, Andrea (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Leighton, Eldin (The Seeing Eye) ;
Bulbena Vilarrasa, Antonio (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
There is a well-established relationship between joint hypermobility and anxiety in humans, that has not previously been investigated in other species. A population of 5575 assistance dogs were scored for both hip hypermobility and 13 behaviour characteristics using previously validated methods. [...]
2019 - 10.1038/s41598-019-45096-0
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 8629
|
|
|
10.
|
|
visitant ::
identificació
alerta personal via correu electrònic o subscribiu-vos al 
canal RSS.
