1.
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34 p, 4.2 MB |
Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals
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Taglialegna, Agustina (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Agrobiotecnología) ;
Navarro Cantero, Susana (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Garnett, James A. (Queen Mary University of London. School of Biological and Chemical Sciences) ;
Matthews, Steve (Imperial College London. Department of Life Sciences) ;
Penades, José R. (University of Glasgow. College of Medical, Veterinary and Life Sciences) ;
Lasa, Iñigo (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Agrobiotecnología) ;
Valle, Jaione (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Agrobiotecnología)
Biofilms are communities of bacteria that grow encased in an extracellular matrix that often contains proteins. The spatial organization and the molecular interactions between matrix scaffold proteins remain in most cases largely unknown. [...]
2016 - 10.1371/journal.ppat.1005711
PLoS pathogens, Vol. 12, issue 6 (June 2016) , p. e1005711
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2.
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37 p, 10.2 MB |
Cryptococcus neoformans can form titan-like cells in vitro in response to multiple signals
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Trevijano-Contador, Núria (Centro Nacional de Microbiología (Espanya)) ;
Oliveira, Haroldo César de (Universidade Estadual Paulista (UNESP). Departamento de Análises Clínicas) ;
García-Rodas, Rocío (Centro Nacional de Microbiología (Espanya)) ;
Rossi, Suélen Andreida (Centro Nacional de Microbiología (Espanya)) ;
Llorente, Irene (Centro Nacional de Microbiología (Espanya)) ;
Zaballos, Ángel (Instituto de Salud Carlos III. Unidad de Genómica) ;
Janbon, Guilhem (Institut Pasteur. Département de Mycologie) ;
Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Zaragoza, Óscar (Centro Nacional de Microbiología (Espanya)) ;
Universitat Autònoma de Barcelona.
Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
Cryptococcus neoformans is an encapsulated pathogenic yeast that can change the size of the cells during infection. In particular, this process can occur by enlarging the size of the capsule without modifying the size of the cell body, or by increasing the diameter of the cell body, which is normally accompanied by an increase of the capsule too. [...]
2018 - 10.1371/journal.ppat.1007007
PLoS pathogens, Vol. 14 issue 5 (2018) , art. e1007007
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3.
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4.
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31 p, 4.4 MB |
The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility
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Gomez Hernández, Laura (Centro de Investigación del Cáncer) ;
Felipe Medina, Natalia (Centro de Investigación del Cáncer) ;
Bejarano Condezo, Yazmine (Centro de Investigación del Cáncer) ;
Garcia Valiente, Rodrigo (Centro de Investigación del Cáncer) ;
Ramos, Isabel (Centro de Investigación del Cáncer) ;
Suja, José Ángel (Universidad Autónoma de Madrid. Unidad de Biologia Celular) ;
Barbero, José Luis (Centro de Investigaciones Biológicas (Madrid)) ;
Roig, I. (Ignasi) (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Sanchez Martin, Manuel. (Universidad de Salamanca. Departamento de Medicina) ;
De Rooij, Dirk G. (Utrecht University. Departent of Biology) ;
Llano, Elena (Departamento de Fisiologia y Farmacologia. Universidad de Salamanca) ;
Martín Pendas, Alberto (Centro de Investigación del Cáncer)
The ubiquitin proteasome system regulates meiotic recombination in yeast through its association with the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [...]
2019 - 10.1371/journal.pgen.1008316
PLoS Genetics, Vol. 15, issue 8 (August 2019) , e1008316
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5.
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14 p, 3.9 MB |
Systems analysis reveals complex biological processes during virus infection fate decisions
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Argilaguet, Jordi (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Pedragosa, Mireia (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Esteve-Codina, Anna (Universitat Pompeu Fabra) ;
Riera, G. (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Vidal Barba, Enric (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal) ;
Peligero-Cruz, C. (Weizmann Institute of Science. Department of Immunology.) ;
Casella, V. (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Andreu, D. (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Kaisho, T. (Osaka University. Laboratory for Immune Regulation. World Premier International Research Center Initiative.) ;
Bocharov, G. (Sechenov First Moscow State Medical University) ;
Ludewig, B. (Institute for Immunobiology.) ;
Heath, S. (Universitat Pompeu Fabra) ;
Meyerhans, A. (Institució Catalana de Recerca i Estudis Avançats (ICREA))
The processes and mechanisms of virus infection fate decisions that are the result of a dynamic virus-immune system interaction with either an efficient effector response and virus elimination or an alleviated immune response and chronic infection are poorly understood. [...]
2019 - 10.1101/gr.241372.118
Genome research, Vol. 29 Núm. 6 (2019) , p. 907-919
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6.
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5 p, 818.2 KB |
First evidence for an association between joint hypermobility and excitability in a non-human species, the domestic dog
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Bowen, Jonathan (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fatjó i Ríos, Jaume (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Serpell, J.A. (University of Pennsylvania. School of Veterinary Medicine) ;
Bulbena-Cabré, Andrea (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Leighton, Eldin (The Seeing Eye) ;
Bulbena, Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
There is a well-established relationship between joint hypermobility and anxiety in humans, that has not previously been investigated in other species. A population of 5575 assistance dogs were scored for both hip hypermobility and 13 behaviour characteristics using previously validated methods. [...]
2019 - 10.1038/s41598-019-45096-0
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 8629
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11 p, 4.2 MB |
Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis
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Penas Pérez, Clara (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Maloof, M.E. (University of Miami Miller School of Medicine. Center for Therapeutic Innovation. Department of Psychiatry and Behavioral Sciences) ;
Stathias, V. (University of Miami Miller School of Medicine. Center for Therapeutic Innovation. Department of Psychiatry and Behavioral Sciences) ;
Long, J. (University of Miami Miller School of Medicine. Department of Surgery) ;
Tan, S.K. (University of Miami Miller School of Medicine. Department of Psychiatry and Behavioral Sciences) ;
Mier, J. (University of Miami Miller School of Medicine. Department of Neurosurgery. Miami Project to Cure Paralysis) ;
Fang, Y. (The Rockefeller University. Laboratory of Development Neurobiology) ;
Valdes, C. (Florida International University. Computing and Information Sciences) ;
Rodriguez-Blanco, J. (University of Miami Miller School of Medicine. Department of Surgery) ;
Chiang, C.M. (University of Texas Southwestern Medical Center. Simmons Comprehensive Cancer Center. Department of Biochemistry and Department of Pharmacology) ;
Robbins, D.J. (University of Miami Miller School of Medicine. Department of Surgery) ;
Liebl, D.J. (University of Miami Miller School of Medicine. Department of Surgery) ;
Lee, J.K. (University of Miami Miller School of Medicine. Department of Neurosurgery. Miami Project to Cure Paralysis) ;
Hatten, M.E. (The Rockefeller University. Laboratory of Development Neurobiology) ;
Clarke, J. (University of Nebraska. Department of Statistics) ;
Ayad, N.G. (University of Miami Miller School of Medicine. Department of Psychiatry and Behavioral Sciences. Center for Therapeutic Innovation. Sylvester Comprehensive Cancer Center. Miami Project to Cure Paralysis)
Cerebellar neuronal progenitors undergo a series of divisions before irreversibly exiting the cell cycle and differentiating into neurons. Dysfunction of this process underlies many neurological diseases including ataxia and the most common pediatric brain tumor, medulloblastoma. [...]
2019 - 10.1038/s41467-019-10799-5
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 3028
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9.
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25 p, 6.5 MB |
Impact of chronic risperidone use on behavior and survival of 3xTg-AD mice model of Alzheimer's disease and mice with normal aging
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Torres-Lista, V. (Universitat Autònoma de Barcelona. Institut de Neurociències.) ;
López-Pousa, S. (Institut d'Assistència Sanitaria. Research Unit and UVaMiD (Memory and Dementia Assessment Unit).) ;
Giménez Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències.)
Psychosis and/or aggression are common problems in dementia, and when severe or persistent, cause considerable patient distress and disability, caregiver stress, and early institutionalization. In 2005, the Food and Drug Administration (FDA) determined that atypical antipsychotics were associated with a significantly greater mortality risk compared to placebo, which prompted the addition of an FDA black-box warning. [...]
2019 - 10.3389/fphar.2019.01061
Frontiers in Pharmacology, Vol. 10 Núm. SEP (2019) , p. 1061
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10.
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15 p, 4.1 MB |
Prenatal Betamethasone interferes with immune system development and alters target cells in autoimmune diabetes
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Perna-Barrull, David (Institut Germans Trias i Pujol) ;
Rodríguez-Fernández, Silvia (Institut Germans Trias i Pujol) ;
Pujol-Autonell, Irma (Institut Germans Trias i Pujol) ;
Gieras, A. (Department of Immunology. University Medical Center Hamburg-Eppendorf) ;
Ampudia Carrasco, Rosa María (Institut Germans Trias i Pujol) ;
Villalba Felipe, Adrián (Institut Germans Trias i Pujol) ;
Glau, L. (Department of Immunology. University Medical Center Hamburg-Eppendorf) ;
Tolosa, E. (Department of Immunology. University Medical Center Hamburg-Eppendorf) ;
Vives Pi, Marta (Institut Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Non-genetic factors are crucial in the pathogenesis of type 1 diabetes (T1D), a disease caused by autoimmunity against insulin-producing β-cells. Exposure to medications in the prenatal period may influence the immune system maturation, thus altering self-tolerance. [...]
2019 - 10.1038/s41598-018-37878-9
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 1235
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