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11 p, 1.8 MB Detectable clonal mosaicism in blood as biomarker of cancer risk in Fanconi anemia / Reina-Castillón, Judith (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Pujol i Calvet, M. Roser (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; López-Sánchez, Marcos (Hospital del Mar (Barcelona, Catalunya)) ; Surrallés i Calonge, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Detectable clonal mosaicism for large chromosomal events has been associated with aging and an increased risk of hematological and some solid cancers. We hypothesized that genetic cancer predisposition disorders, such as Fanconi anemia (FA), could manifest a high rate of chromosomal mosaic events (CMEs) in peripheral blood, which could be used as early biomarkers of cancer risk. [...]
2016 - 10.1182/bloodadvances.2016000943
Blood advances, Vol. 1 (2017) , p. 319-329  
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