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Resultados globales: 2 registros encontrados en 0.02 segundos.
Artículos, Encontrados 2 registros
Artículos Encontrados 2 registros  
1.
27 p, 8.1 MB Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin / Liang, Wen-Wei (Washington University in St. Louis) ; Lu, Rita Jui-Hsien Lu (Washington University in St. Louis) ; Jayasinghe, Reyka G. (Washington University in St. Louis) ; Foltz, Steven M. (Washington University in St. Louis) ; Porta-Pardo, Eduard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Geffen, Yifat (Massachusetts General Hospital (Boston)) ; Wendl, Michael C. (Department of Mathematics. Washington University in St. Louis) ; Lazcano, Rossana (Departments of Pathology & Genomic Medicine. The University of Texas MD Anderson Cancer Center) ; Kolodziejczak, Iga (Medical University of Warsaw) ; Song, Yizhe (Washington University in St. Louis) ; Govindan, Akshay (Washington University in St. Louis) ; Demicco, Elisabeth G. (University of Toronto) ; Li, Xiang (Washington University in St. Louis) ; Li, Yize (Washington University in St. Louis) ; Sethuraman, Sunantha (Washington University in St. Louis) ; Payne, Samuel H. (Department of Biology. Brigham Young University) ; Fenyö, David (Department of Biochemistry and Molecular Pharmacology. NYU Grossman School of Medicine) ; Rodriguez, Henry (Office of Cancer Clinical Proteomics Research. National Cancer Institute) ; Wiznerowicz, Maciej (Poznań University of Medical Sciences) ; Shen, Hui (Van Andel Research Institute) ; Mani, D.R. (Broad Institute of Massachusetts Institute of Technology and Harvard) ; Rodland, Karin D. (Developmental. and Cancer Biology. Oregon Health & Science University) ; Lazar, Alexander J. (Departments of Pathology & Genomic Medicine. The University of Texas MD Anderson Cancer Center) ; Robles, Ana I. (Office of Cancer Clinical Proteomics Research) ; Ding, Li (Washington University in St. Louis) ; Universitat Autònoma de Barcelona
DNA methylation plays a critical role in establishing and maintaining cellular identity. However, it is frequently dysregulated during tumor development and is closely intertwined with other genetic alterations. [...]
2023 - 10.1016/j.ccell.2023.07.013
Cancer Cell, Vol. 41 Núm. 9 (november 2023) , p. 1567-1585.e7  
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2.
12 p, 1.2 MB Independent Validation of Early-Stage Non-Small Cell Lung Cancer Prognostic Scores Incorporating Epigenetic and Transcriptional Biomarkers With Gene-Gene Interactions and Main Effects / Zhang, R. (Department of Medical Oncology. Jinling Hospital. School of Medicine. Nanjing University) ; Chen, C. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Dong, X. (Department of Epidemiology and Biostatistics. School of Public Health. Southeast University) ; Shen, S. (China International Cooperation Center for Environment and Human Health. Nanjing Medical University) ; Lai, L. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; He, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; You, D. (Department of Environmental Health. Harvard T. H. Chan School of Public Health) ; Lin, L. (Department of Environmental Health. Harvard T. H. Chan School of Public Health) ; Zhu, Y. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Huang, H. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Wei, Liangmin (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, X. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Li, Y. (Department of Biostatistics. University of Michigan) ; Guo, Y. (Department of Biostatistics. Harvard T. H. Chan School of Public Health) ; Duan, W. (Department of Bioinformatics. School of Biomedical Engineering and Informatics. Nanjing Medical University) ; Liu, L. (Department of Preventive Medicine. Medical School of Ningbo University) ; Su, L. (Department of Environmental Health. Harvard T. H. Chan School of Public Health) ; Shafer, A. (Harvard Medical School) ; Fleischer, T. (Department of Cancer Genetics. Institute for Cancer Research. Oslo University Hospital) ; Moksnes Bjaanæs, M. (Department of Cancer Genetics. Institute for Cancer Research. Oslo University Hospital) ; Karlsson, A. (Division of Oncology and Pathology. Department of Clinical Sciences. Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Planck, M. (Division of Oncology and Pathology. Department of Clinical Sciences. Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Wang, R. (Department of Medical Oncology. Jinling Hospital. School of Medicine. Nanjing University) ; Staaf, J. (Division of Oncology and Pathology. Department of Clinical Sciences. Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Helland, Å. (Institute of Clinical Medicine. University of Oslo) ; Esteller, M. (Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut) ; Wei, Y. (China International Cooperation Center for Environment and Human Health. Nanjing Medical University) ; Chen, F. (Jiangsu Key Laboratory of Cancer Biomarkers. Prevention and Treatment. Cancer Center. Collaborative Innovation Center for Cancer Personalized Medicine. Nanjing Medical University) ; Christiani, David C (Harvard Medical School) ; Universitat Autònoma de Barcelona
Background: DNA methylation and gene expression are promising biomarkers of various cancers, including non-small cell lung cancer (NSCLC). Besides the main effects of biomarkers, the progression of complex diseases is also influenced by gene-gene (G×G) interactions. [...]
2020 - 10.1016/j.chest.2020.01.048
Chest, Vol. 158 Núm. 2 (august 2020) , p. 808-819  
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