Results overview: Found 18 records in 0.02 seconds.
Articles, 16 records found
Research literature, 2 records found
Articles 16 records found  1 - 10next  jump to record:
1.
13 p, 3.4 MB Overexpression of the vascular brassinosteroid receptor BRL3 confers drought resistance without penalizing plant growth / Fábregas, Norma (Centre de Recerca en Agrigenòmica) ; Lozano Elena, Fidel (Centre de Recerca en Agrigenòmica) ; Blasco Escámez, David (Centre de Recerca en Agrigenòmica) ; Tohge, Takayuki (NAIST Graduate school of Biological Sciences) ; Martínez Andújar, Cristina (CEBAS-CSIC) ; Albacete, Alfonso (CEBAS-CSIC) ; Osorio, Sonia (Universidad de Málaga) ; Bustamante Montoya, Mariana (Centre de Recerca en Agrigenòmica) ; Riechmann, José Luis (Centre de Recerca en Agrigenòmica) ; Nomura, Takahito (Utsunomiya University) ; Yokota, Takao (Teikyo University) ; Conesa, Ana (University of Florida) ; Pérez Alfocea, Francisco (CEBAS-CSIC) ; Fernie, Alisdair R. (Max Planck Institute of Molecular Plant Physiology) ; Caño Delgado, Ana I. (Centre de Recerca en Agrigenòmica)
Drought represents a major threat to food security. Mechanistic data describing plant responses to drought have been studied extensively and genes conferring drought resistance have been introduced into crop plants. [...]
2018 - 10.1038/s41467-018-06861-3
Nature communications, Vol. 9 (November 2018) , art. 4680  
2.
18 p, 2.3 MB The genomic footprints of the fall and recovery of the crested ibis / Feng, Sahaohong (University of Chinese Academy of Sciences) ; Fang, Qui (China National GeneBank) ; Barnett, Ross (Københavns Universitet. Sektion for GeoGenetik) ; Li, Cai (China National GeneBank) ; Han, Sojung (Institute of Evolutionary Biology) ; Kuhlwilm, Martin (Institute of Evolutionary Biology) ; Zhou, Long (China National GeneBank) ; Pan, Hailin (China National GeneBank) ; Deng, Yuan (China National GeneBank) ; Chen, Guangji (University of Chinese Academy of Sciences) ; Gamauf, Anita (Naturhistorisches Museum Wien) ; Woog, Friederike (Staatliches Museum für Naturkunde) ; Prys-Jones, Robert (The Natural History Museum) ; Marquès i Bonet, Tomàs, 1975- (Institut Català de Paleontologia Miquel Crusafont) ; P.Gilbert, M. Thomas (Københavns Universitet. Sektion for GeoGenetik) ; Zhang, Guojie (China National GeneBank)
Human-induced environmental change and habitat fragmentation pose major threats to biodiversity and require active conservation efforts to mitigate their consequences. Genetic rescue through translocation and the introduction of variation into imperiled populations has been argued as a powerful means to preserve, or even increase, the genetic diversity and evolutionary potential of endangered species [1, 2, 3, 4]. [...]
2019 - 10.1016/j.cub.2018.12.008
Current biology, Vol. 29, issue 2 (Jan. 2019) , p. 340-349  
3.
7 p, 176.2 KB Incorporating BEAMing technology as a liquid biopsy into clinical practice for the management of colorectal cancer patients : an expert taskforce review / García-Foncillas, J (Hospital Universitario Fundación Jiménez Díaz) ; Alba, E (Hospital Universitario Regional Virgen de la Victoria, IBIMA, Málaga) ; Aranda, E (Hospital Reina Sofía, Cordoba) ; Díaz Rubio, E (Universidad Complutense de Madrid. Hospital Clínico San Carlos) ; López López, R (Hospital Clínico Universitario (Santiago de Compostela)) ; Tabernero Caturla, Josep (Universitat Autònoma de Barcelona) ; Vivancos, A (Vall d'Hebron Institut d'Oncologia)
The importance of mutation identification for advanced colorectal cancer treatment with anti-epidermal growth factor receptor agents is well established. However, due to delays in turnaround time, low-quality tissue samples, and/or lack of standardization of testing methods a significant proportion of patients are being treated without the information that Kirsten rat sarcoma and neuroblastoma rat sarcoma (RAS) testing can provide. [...]
2017 - 10.1093/annonc/mdx501
Annals of Oncology, Vol. 28 (september 2017) , p. 2943-2949  
4.
10 p, 1.9 MB Nuclear IGF-1R predicts chemotherapy and targeted therapy resistance in metastatic colorectal cancer / Codony Servat, Jordi (Institut Germans Trias i Pujol. Institut Català d'Oncologia) ; Cuatrecasas Freixas, Miriam ; Asensio, Elena (Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Montironi, Carla (Hospital Clínic) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol. Institut Català d'Oncologia) ; Marín Aguilera, Mercedes (Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Horndler, Carlos (Hospital Miguel Servet) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol. Institut Català d'Oncologia) ; Rubini, Michele (Department of Experimental and Diagnostic Medicine, University of Ferrara) ; Jares, Pedro (Hospital Clínic) ; Reig, Oscar (Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Victoria, Iván (Medical Oncology Department, Hospital Clínic, Translational Genomics and Targeted Therapeutics in Solid Tumors Group, IDIBAPS, Universitat de Barcelona) ; Gaba, Lydia (Medical Oncology Department, Hospital Clínic, Translational Genomics and Targeted Therapeutics in Solid Tumors Group, IDIBAPS, Universitat de Barcelona) ; Martín Richard, Marta (Institut d'Investigació Biomèdica Sant Pau) ; Alonso, Vicente (Hospital Miguel Servet) ; Escudero, Pilar (Hospital Clínico Universitatio Lozano Blesa) ; Fernández-Martos, Carlos (Instituto Valenciano de Oncología) ; Feliu, Jaime (Hospital La Paz, CIBERONC) ; Méndez, Jose Carlos (Centro Oncológico de Galicia) ; Méndez, Miguel (Hospital de Móstoles) ; Gallego, Javier (Hospital de Elche) ; Salud, Antonieta (Hospital Arnau de Vilanova) ; Rojo, Federico (Pathology Department, Fundación Jiménez Diaz University) ; Castells, Antoni (Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Prat, Aleix (Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Rosell, Rafael (Institut Germans Trias i Pujol. Institut Català d'Oncologia) ; García-Albéniz, Xabier (Harvard T.H. Chan School of Public Health) ; Camps, Jordi (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Maurel, Joan (Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS))
Although chemotherapy is the cornerstone treatment for patients with metastatic colorectal cancer (mCRC), acquired chemoresistance is common and constitutes the main reason for treatment failure. Monoclonal antibodies against insulin-like growth factor-1 receptor (IGF-1R) have been tested in pre-treated mCRC patients, but results have been largely deceiving. [...]
2017 - 10.1038/bjc.2017.279
British Journal of Cancer, Vol. 117 (november 2017) , p. 1777-1786  
5.
4 p, 393.4 KB Copper(II) and the pathological H50Q α-synuclein mutant : environment meets genetics / Villar-Piqué, Anna (University Medical Centre Göottingen. Department of Neurodegeneration and Restorative Research) ; Rossetti, Giulia (Jülich Forschungszentrum. Institut für Neurowissenschaften und Medizin) ; Ventura i Zamora, Salvador (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Carloni, Paolo (Jülich Forschungszentrum. Institut für Neurowissenschaften und Medizin) ; Fernández, Claudio O. (Max Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario) ; Outeiro, Tiago Fleming (University Medical Centre Göottingen. Department of Neurodegeneration and Restorative Research) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Copper is one of the metals described to bind the Parkinson disease-related protein α-synuclein (aSyn), and to promote its aggregation. Although histidine at position 50 in the aSyn sequence is one of the most studied copper-anchoring sites, its precise role in copper binding and aSyn aggregation is still unclear. [...]
2017 - 10.1080/19420889.2016.1270484
Communicative & integrative Biology, Vol. 10, no. 1 (2017) , e127048  
6.
14 p, 652.3 KB Adaptive evolution is substantially impeded by Hill–Robertson interference in Drosophila / Castellano Esteve, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Coronado Zamora, Marta (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Campos, Jose L. (University of Edinburgh. Institute of Evolutionary Biology, School of Biological Sciences) ; Barbadilla Prados, Antonio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Eyre-Walker, Adam (University of Sussex. Centre for the Study of Evolution, School of Life Sciences) ; Universitat Autònoma de Barcelona. Departament de Genètica i Microbiologia
Hill–Robertson interference (HRi) is expected to reduce the efficiency of natural selection when two or more linked selected sites do not segregate freely, but no attempt has been done so far to quantify the overall impact of HRi on the rate of adaptive evolution for any given genome. [...]
2015 - 10.1093/molbev/msv236
Molecular biology and evolution, Vol. 33, Núm. 2 (October 2015) , p. 442-455  
7.
14 p, 23.8 MB Shining Light On An mGlu5 Photoswitchable NAM : A Theoretical Perspective / Dalton, James A.R. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Lans, Isaias (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Rovira Algans, Xavier (Institut de Génomique Fonctionnelle) ; Malhaire, Fanny (Institut de Génomique Fonctionnelle) ; Gómez-Santacana, Xavier (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Pittolo, Silvia (Institute for Bioengineering of Catalonia (IBEC)) ; Gorostiza, Pau (Institute for Bioengineering of Catalonia (IBEC)) ; Llebaria, Amadeu (Institut de Química Avançada de Catalunya) ; Goudet, Cyril (Institut de Génomique Fonctionnelle) ; Pin, Jean-Philippe (Institut de Génomique Fonctionnelle) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències)
Metabotropic glutamate receptors (mGluRs) are important drug targets because of their involvement in several neurological diseases. Among mGluRs, mGlu5 is a particularly high-profile target because its positive or negative allosteric modulation can potentially treat schizophrenia or anxiety and chronic pain, respectively. [...]
2016 - 10.2174/1570159X13666150407231417
Curr Neuropharmacol, Vol. 14, Num. 5 (2016) , p. 441-454  
8.
14 p, 3.1 MB The importance of a gatekeeper residue on the aggregation of transthyretin / Sant'Anna, Ricardo (Instituto de Bioquímica Médica Leopoldo de Meis) ; Braga, Carolina (Instituto de Bioquímica Médica Leopoldo de Meis) ; Varejão, Nathalia (Instituto de Bioquímica Médica Leopoldo de Meis) ; Pimenta, Karinne M. (Instituto de Bioquímica Médica Leopoldo de Meis) ; Graña Montes, Ricardo (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Alves, Aline (Instituto de Bioquímica Médica Leopoldo de Meis) ; Cortines, Juliana (Instituto de Microbiologia Professor Paulo de Goés) ; Cordeiro, Yraima (Universidade Federal do Rio de Janeiro. Faculdade de Farmácia) ; Ventura i Zamora, Salvador (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Foguel, Debora (From the Instituto de Bioquímica Médica Leopoldo de Meis, Programa de Biologia Estrutural)
Background: Proteins have adopted negative design to diminish aggregation. Results: The replacement of Lys-35 by Leu increases the amyloidogenicity of the 26–57 segment of TTR as well as the entire protein. [...]
2014 - 10.1074/jbc.M114.563981
The Journal of biological chemistry, Vol. 289, no. 41 (Oct. 2014) , p. 28324-28337  
9.
18 p, 638.8 KB Gene alterations at Drosophila inversion breakpoints provide prima facie evidence for natural selection as an explanation for rapid chromosomal evolution / Guillén Montalbán, Yolanda (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Ruiz, Alfredo, (Ruiz Panadero) (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Chromosomal inversions have been pervasive during the evolution of the genus Drosophila, but there is significant variation between lineages in the rate of rearrangement fixation. D. mojavensis, an ecological specialist adapted to a cactophilic niche under extreme desert conditions, is a chromosomally derived species with ten fixed inversions, five of them not present in any other species. [...]
2012 - 10.1186/1471-2164-13-53
BMC genomics, Vol. 13 (2012) , art. 53  
10.
16 p, 773.0 KB Jitterbug : somatic and germline transposon insertion detection at single-nucleotide resolution / Hénaff, Elizabeth (Centre de Recerca en Agrigenòmica) ; Zapata, Luís (Centre de Regulació Genòmica (Barcelona)) ; Casacuberta i Suñer, Josep M. (Centre de Recerca en Agrigenòmica) ; Ossowski, Stephan (Centre de Regulació Genòmica (Barcelona))
2015 - 10.1186/s12864-015-1975-5
BMC Genomics, Vol. 16 art. 768 (2015)  

Articles : 16 records found   1 - 10next  jump to record:
Research literature 2 records found  
1.
1 p, 4.8 MB Laminopathies : the nuclear lamina alteration / Mir Pérez, Cristina ; Benet i Català, Jordi, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Ciències Biomèdiques [832]  
2.
1 p, 4.9 MB Prenatal study of the Gli family proteins in the cerebellar development under weaver condition / Alacid Romero, Sergi ; Martí Clúa, Joaquim, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Genètica [833]  

Interested in being notified about new results for this query?
Set up a personal email alert or subscribe to the RSS feed.