Results overview: Found 8 records in 0.02 seconds.
Articles, 6 records found
Research literature, 2 records found
Articles 6 records found  
1.
13 p, 3.5 MB Proteomic Analysis of Human iPSC-Derived Neural Stem Cells and Motor Neurons Identifies Proteasome Structural Alterations / Álvarez Pérez, Iñaki (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Tirado-Herranz, Adrián (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Alvarez-Palomo, Belén (Banc de Sang i Teixits (Barcelona, Catalunya)) ; Osete, Jordi Requena (Oslo University Hospital (Oslo, Noruega)) ; Edel, Michael J (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques)
Background: Proteins targeted by the ubiquitin proteasome system (UPS) are identified for degradation by the proteasome, which has been implicated in the development of neurodegenerative diseases. Major histocompatibility complex (MHC) molecules present peptides broken down by the proteasome and are involved in neuronal plasticity, regulating the synapse number and axon regeneration in the central or peripheral nervous system during development and in brain diseases. [...]
2023 - 10.3390/cells12242800
Cells, Vol. 12 (december 2023)  
2.
11 p, 2.5 MB Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis / Kandel, Prasanna (Department of Biochemistry and Molecular Biomedicine. Institute of Biomedicine. University of Barcelona) ; Semerci, Fatih (Universitat de Barcelona. Institut de Biomedicina. Departament de Bioquímica i Biomedicina Molecular) ; Mishra, Rachana (Jan and Dan Duncan Neurological Research Institute. Texas Children's Hospital) ; Choi, Willian (Medical Scientist Training Program. Baylor College of Medicine) ; Bajic, Aleksandar (Department of Molecular and Human Genetics. Baylor College of Medicine) ; Baluya, Dodge (Department of Interventional Radiology. University of Texas MD Anderson Cancer Center) ; Ma, Li Hua (NMR and Drug Metabolism Advanced Technology Cores. Baylor College of Medicine) ; Chen, Kevin (Department of Biosciences. Rice University) ; Cao, Austin C. (Department of Chemistry. Rice University) ; Phongmekhin, Tipwarin (Department of Biosciences. Rice University) ; Matinyan, Nick (Verna and Marrs McLean Department of Biochemistry and Molecular Biology. Baylor College of Medicine) ; Jimenez-Panizo, Alba (Universitat de Barcelona. Institut de Biomedicina. Departament de Bioquímica i Biomedicina Molecular) ; Chamakuri, Srinivas (Department of Pathology and Immunology. Baylor College of Medicine) ; Raji, Idris O. (Department of Pharmacology & Chemical Biology. Baylor College of Medicine) ; Chang, Lyra (Department of Pharmacology & Chemical Biology. Baylor College of Medicine) ; Fuentes-Prior, Pablo (Institut d'Investigació Biomèdica Sant Pau) ; MacKenzie, Kevin R. (Department of Molecular and Cellular Biology. Baylor College of Medicine) ; Benn, Caroline L. (Pfizer Regenerative Medicine) ; Estebanez-Perpiña, Eva (Department of Biochemistry and Molecular Biomedicine. Institute of Biomedicine. University of Barcelona) ; Venken, Koen (Verna and Marrs McLean Department of Biochemistry and Molecular Biology. Baylor College of Medicine) ; Moore, David D. (Department of Molecular and Cellular Biology. Baylor College of Medicine) ; Young, Damian W. (Center for Drug Discovery. Baylor College of Medicine) ; Maletic-Savatic, Mirjana (Department of Neuroscience. Baylor College of Medicine)
Neural stem cells, the source of newborn neurons in the adult hippocampus, are intimately involved in learning and memory, mood, and stress response. Despite considerable progress in understanding the biology of neural stem cells and neurogenesis, regulating the neural stem cell population precisely has remained elusive because we have lacked the specific targets to stimulate their proliferation and neurogenesis. [...]
2022 - 10.1073/pnas.2023784119
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119 Núm. 13 (March 2022) , p. e2023784119  
3.
10 p, 1.5 MB Angiogenin in the Neurogenic Subventricular Zone After Stroke / Gabriel Salazar, Marina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lei, Ting (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Grayston, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Costa, Carme (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Medina-Gutiérrez, Esperanza (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Comabella, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rosell Novel, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Ischemic stroke is a leading cause of death and disability worldwide with effective acute thrombolytic treatments. However, brain repair mechanisms related to spontaneous or rehabilitation-induced recovery are still under investigation, and little is known about the molecules involved. [...]
2021 - 10.3389/fneur.2021.662235
Frontiers in neurology, Vol. 12 (june 2021)  
4.
11 p, 4.2 MB Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis / Penas Pérez, Clara (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Maloof, M. E. (University of Miami Miller School of Medicine. Center for Therapeutic Innovation. Department of Psychiatry and Behavioral Sciences) ; Stathias, V. (University of Miami Miller School of Medicine. Center for Therapeutic Innovation. Department of Psychiatry and Behavioral Sciences) ; Long, J. (University of Miami Miller School of Medicine. Department of Surgery) ; Tan, S. K. (University of Miami Miller School of Medicine. Department of Psychiatry and Behavioral Sciences) ; Mier, J. (University of Miami Miller School of Medicine. Department of Neurosurgery. Miami Project to Cure Paralysis) ; Fang, Y. (The Rockefeller University. Laboratory of Development Neurobiology) ; Valdes, C. (Florida International University. Computing and Information Sciences) ; Rodriguez-Blanco, J. (University of Miami Miller School of Medicine. Department of Surgery) ; Chiang, C. M. (University of Texas Southwestern Medical Center. Simmons Comprehensive Cancer Center. Department of Biochemistry and Department of Pharmacology) ; Robbins, D. J. (University of Miami Miller School of Medicine. Department of Surgery) ; Liebl, D. J. (University of Miami Miller School of Medicine. Department of Surgery) ; Lee, J. K. (University of Miami Miller School of Medicine. Department of Neurosurgery. Miami Project to Cure Paralysis) ; Hatten, M. E. (The Rockefeller University. Laboratory of Development Neurobiology) ; Clarke, J. (University of Nebraska. Department of Statistics) ; Ayad, N. G. (University of Miami Miller School of Medicine. Department of Psychiatry and Behavioral Sciences. Center for Therapeutic Innovation. Sylvester Comprehensive Cancer Center. Miami Project to Cure Paralysis)
Cerebellar neuronal progenitors undergo a series of divisions before irreversibly exiting the cell cycle and differentiating into neurons. Dysfunction of this process underlies many neurological diseases including ataxia and the most common pediatric brain tumor, medulloblastoma. [...]
2019 - 10.1038/s41467-019-10799-5
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 3028  
5.
13 p, 2.8 MB Global proteomic and methylome analysis in human induced pluripotent stem cells reveals overexpression of a human TLR3 affecting proper innate immune response signaling / Requena, Jordi (Universitat de Barcelona. Departament de Biomedicina) ; Álvarez Palomo, Ana Belén (Universitat de Barcelona. Departament de Biomedicina) ; Codina, Montserrat (Universitat de Barcelona. Departament de Biomedicina) ; Delgado Morales, Raúl (Institut d'Investigació Biomèdica de Bellvitge) ; Moran, S (Institut d'Investigació Biomèdica de Bellvitge) ; Esteller, M. (Institut d'Investigació Biomèdica de Bellvitge) ; Sal, Martí (Universitat de Barcelona. Departament de Biomedicina) ; Juan, Manel (Hospital Clínic i Provincial de Barcelona) ; Boronat Barado, Anna (Hospital Clínic i Provincial de Barcelona) ; Consiglio, Antonella (Institut d'Investigació Biomèdica de Bellvitge) ; Bogle, Orleigh Addeleccia (Universitat de Barcelona. Departament de Biomedicina) ; Wolvetang, Ernst (University of Queensland. Australian Institute for Bioengineering and Nanotechnology) ; Ovchinnikov, Dmitry (University of Queensland. Australian Institute for Bioengineering and Nanotechnology) ; Álvarez Pérez, Iñaki (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Jaraquemada, Dolores (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Mezquita Pla, Jovita (Universitat de Barcelona. Departament de Biomedicina) ; Oliva Virgili, Rafael (Universitat de Barcelona. Departament de Biomedicina) ; Edel, Michael J.. (Universitat de Barcelona. Departament de Biomedicina)
When considering the clinical applications of autologous cell replacement therapy of human induced pluripotent stem cells (iPSC)-derived cells, there is a clear need to better understand what the immune response will be before we embark on extensive clinical trials to treat or model human disease. [...]
2019 - 10.1002/stem.2966
Stem Cells, Vol. 37, issue 4 (April 2019) , p. 476-488  
6.
20 p, 974.0 KB Effects of the post-spinal cord injury microenvironment on the differentiation capacity of human neural stem cells derived from induced pluripotent stem cells / López-Serrano, Clara (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Torres Espín, Abel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Hernández Martín, Joaquim (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Álvarez Palomo, Ana Belén (Universitat de Barcelona) ; Requena, Jordi (Universitat de Barcelona) ; Gasull, Xavier (Universitat de Barcelona) ; Edel, Michael J (Universitat de Barcelona) ; Navarro, X. (Xavier) (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Spinal cord injury (SCI) causes loss of neural functions below the level of the lesion due to interruption of spinal pathways and secondary neurodegenerative processes. The transplant of neural stem cells (NSCs) is a promising approach for the repair of SCI. [...]
2016 - 10.3727/096368916X691312
Cell transplantation, Vol. 25, núm. 10 (2016) , p. 1833-1852  

Research literature 2 records found  
1.
1 p, 8.8 MB Therapetic uses of neural stem cells in neurological diseases / Faura, Júlia ; Nogués, C. (Carme), (Carme) dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Biologia [812]  
2.
1 p, 360.8 KB Alzheimer disease : how could stem cells help? / Izquierdo Barrionuevo, Cristina ; Nogués, C. (Carme), , dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Ciències Biomèdiques [832]  

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