Resultats globals: 9 registres trobats en 0.02 segons.
Articles, 9 registres trobats
Articles 9 registres trobats  
1.
16 p, 2.3 MB Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage / Gregorio-Rocasolano Barbany, Núria de (Institut Germans Trias i Pujol) ; Martí Sistac, Octavi (Universitat Autònoma de Barcelona) ; Ponce, Jovita (Institut Germans Trias i Pujol) ; Castelló Ruiz, María (Institut d'Investigació Sanitària La Fe) ; Millán Torné, Mònica (Hospital Universitari Germans Trias i Pujol. Departament de Neurocències) ; Guirao, Verónica (Institut Germans Trias i Pujol) ; García Yébenes, Isaac (Universidad Complutense de Madrid. Departamento de Farmacología) ; Salom, Juan B. (Institut d'Investigació Sanitària La Fe) ; Ramos Cabrer, Pedro (Hospital Clínico Universitario de Santiago. Departamento de Neurología) ; Alborch, Enrique (Institut d'Investigació Sanitària La Fe) ; Lizasoain, Ignacio (Universidad Complutense de Madrid. Departamento de Farmacología) ; Castillo, José (Hospital Clínico Universitario de Santiago. Departamento de Neurología) ; Dávalos, Antoni (Hospital Universitari Germans Trias i Pujol. Departament de Neurocències) ; Gasull Dalmau, Teresa (Institut Germans Trias i Pujol)
Despite transferrin being the main circulating carrier of iron in body fluids, and iron overload conditions being known to worsen stroke outcome through reactive oxygen species (ROS)-induced damage, the contribution of blood transferrin saturation (TSAT) to stroke brain damage is unknown. [...]
2018 - 10.1016/j.redox.2017.11.026
Redox biology, Vol. 15 (May 2018) , p. 143-158  
2.
32 p, 2.8 MB Beneficial effects of IL-37 after spinal cord injury in mice / Coll Miró, Marina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Santos Nogueira, Eva (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Torres Espín, Abel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bufler, P. (Ludwig-Maximilians-Universität München. Department of Pediatrics) ; Dinarello, CA. (Radboud University Medical Center. Department of Medicine) ; López Vales, Ruben (Universitat Autònoma de Barcelona. Institut de Neurociències)
IL-37, a member of the IL-1 family, broadly reduces innate inflammation as well as acquired immunity. Whether the antiinflammatory properties of IL-37 extend to the central nervous system remains unknown, however. [...]
2016 - 10.1073/pnas.1523212113
Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, issue 5 (2016) , p. 1411-1416  
3.
11 p, 1.2 MB Zebrafish is a predictive model for identifying compounds that protect against brain toxicity in severe acute organophosphorus intoxication / Faria, Melissa (Institut de Diagnòstic Ambiental i Estudis de l'Aigua - CSIC) ; Prats, Eva (Centre d'Investigació i Desenvolupament - CSIC) ; Padrós, Francesc 1965- (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Soares, Amadeu M. V. M. (University of Aveiro. Centre of Environmental and Marine Studies (Portugal)) ; Raldúa, Demetrio (Institut de Diagnòstic Ambiental i Estudis de l'Aigua - CSIC)
Acute organophosphorus (OP) intoxication is aworldwide clinical and public health problem. In addition to cholinergic crisis, neurodegeneration and brain damage are hallmarks of the severe form of this toxidrome. [...]
2017 - 10.1007/s00204-016-1851-3
Archives of Toxicology, Vol. 91, Núm. 4 (April 2017) , p. 1891-1901  
4.
13 p, 3.3 MB Maresin 1 promotes inflammatory resolution, neuroprotection, and functional neurological recovery after Spinal Cord Injury / Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Santos Nogueira, Eva (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Gronert, Karsten (University of California (Berkeley)) ; Sullivan, Aaron B. (University of California (Berkeley)) ; Kopp, Marcel A. (Charité-Universitätsmedizin Berlin (Berlin, Alemanya)) ; Brommer, Benedikt (Charité-Universitätsmedizin Berlin (Berlin, Alemanya)) ; David, Samuel (McGill University Health Centre (Montreal, Canadà)) ; Schwab, Jan M. (Charité-Universitätsmedizin Berlin (Berlin, Alemanya)) ; López Vales, Ruben (Universitat Autònoma de Barcelona. Institut de Neurociències)
Resolution of inflammation is defective after spinal cord injury (SCI), which impairs tissue integrity and remodeling and leads to functional deficits. Effective pharmacological treatments for SCI are not currently available. [...]
2017 - 10.1523/JNEUROSCI.1395-17.2017
The Journal of Neuroscience, Vol. 37, Núm. 48 (November 2017) , p. 11731-11743  
5.
20 p, 1.0 MB The Role of Citicoline in Neuroprotection and Neurorepair in Ischemic Stroke / Alvárez Sabín, J. (José), (Universitat Autònoma de Barcelona. Departament de Medicina) ; Román, Gustavo C. (Nantz National Alzheimer Center (Houston, Estats Units d'Amèrica). Department of Neurology)
Advances in acute stroke therapy resulting from thrombolytic treatment, endovascular procedures, and stroke units have improved significantly stroke survival and prognosis; however, for the large majority of patients lacking access to advanced therapies stroke mortality and residual morbidity remain high and many patients become incapacitated by motor and cognitive deficits, with loss of independence in activities of daily living. [...]
2013 - 10.3390/brainsci3031395
Brain Sciences, Vol. 3 Núm. 3 (September 2013) , p. 1395-1414  
6.
30 p, 219.1 KB IL-4 drives microglia and macrophages toward a phenotype conducive for tissue repair and functional recovery after spinal cord injury / Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Amo Aparicio, Jesús (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Martínez Muriana, Anna (Universitat Autònoma de Barcelona. Institut de Neurociències) ; López Vales, Ruben (Universitat Autònoma de Barcelona. Institut de Neurociències)
Macrophages and microglia play a key role in the maintenance of nervous system homeostasis. However, upon different challenges, they can adopt several phenotypes, which may lead to divergent effects on tissue repair. [...]
2016 - 10.1002/glia.23041
Glia, Vol. 64 Núm. 12 (2016) , p. 2079-2092
9 documents
7.
12 p, 211.7 KB Delineating the factors and cellular mechanisms involved in the survival of cerebellar granule neurons. / Xifro Collsamata, Francesc Xavier (Universitat de Girona. Departament de Ciències Mèdiques) ; Rodríguez Álvarez, José (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Cerebellar granule neurons (CGNs) constitute the most abundant neuronal population in the mammalian brain. Their postnatal generation and the feasibility to induce their apoptotic death in vitro make them an excellent model to study the effect of several neurotransmitters and neurotrophins. [...]
2015 - 10.1007/s12311-015-0646-z
Cerebellum, Vol. 14, Num. 3 (June 2015)  
8.
12 p, 3.5 MB Activation of lysophosphatidic acid receptor type 1 (LPA1) contributes to pathophysiology of spinal cord injury / Santos Nogueira, Eva (Universitat Autònoma de Barcelona. Institut de Neurociències) ; López-Serrano, Clara (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Hernández Martín, Joaquim (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Lago Pérez, Natalia (Institut Pasteur de Montevideo. Laboratorio de Neuroinflamación y Terapia Génica) ; Astudillo, Alma M. (Consejo Superior de Investigaciones Científicas. Instituto de Biología y Genética Molecular) ; Balsinde, Jesús (Consejo Superior de Investigaciones Científicas. Instituto de Biología y Genética Molecular) ; Estivill-Torrus, Guillermo (Instituto de Investigación Biomédica de Málaga) ; Rodríguez de Fonseca Fernando (Instituto de Investigación Biomédica de Málaga) ; Chun, Jerold (Scripps Research Institute. Dorris Neuroscience Center) ; López Vales, Rubén (Universitat Autònoma de Barcelona. Institut de Neurociències)
Lysophosphatidic acid (LPA) is an extracellular lipid mediator involved in many physiological functions that signals through six known G-protein-coupled receptors (LPA1–LPA6). A wide range of LPA effects have been identified in the CNS, including neural progenitor cell physiology, astrocyte and microglia activation, neuronal cell death, axonal retraction, and development of neuropathic pain. [...]
2015 - 10.1523/JNEUROSCI.4703-14.2015
The Journal of neuroscience, Vol. 35, Num. 28 (2015) , p. 10224-10235  
9.
44 p, 2.8 MB Effects of voluntary physical exercise, citicoline, and combined treatment on object recognition memory, neurogenesis and neuroprotection after traumatic brain injury in rats / Jacotte Simancas, Alejandra (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Costa Miserachs, David (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Coll-Andreu, Margalida (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Torras Garcia, Meritxell (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Borlongan, César V. (University of South Florida. Center of Excellence for Aging and Brain Repair) ; Portell-Cortés, Isabel (Universitat Autònoma de Barcelona. Institut de Neurociències)
The biochemical and cellular events that lead to secondary neural damage after traumatic brain injury (TBI) contribute to long-term disabilities, including memory deficits. There is a need to search for single and/or combined treatments aimed at reducing these TBI-related dysfunctions. [...]
2015 - 10.1089/neu.2014.3502
Journal of neurotrauma, Vol. 32, Num. 10 (2015) , p. 739-751  

Us interessa rebre alertes sobre nous resultats d'aquesta cerca?
Definiu una alerta personal via correu electrònic o subscribiu-vos al canal RSS.