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Resultados globales: 8 registros encontrados en 0.02 segundos.
Artículos, Encontrados 8 registros
Artículos Encontrados 8 registros  
1.
21 p, 1.3 MB Predictive Biomarkers of Oxaliplatin-Induced Peripheral Neurotoxicity / Velasco, Roser (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Alemany, Montserrat (Institut d'Investigació Biomèdica de Bellvitge) ; Villagrán, Macarena (Institut d'Investigació Biomèdica de Bellvitge) ; Argyriou, Andreas A. (Neurology Department, "Saint Andrew's" State General Hospital of Patras)
Oxaliplatin (OXA) is a platinum compound primarily used in the treatment of gastrointestinal cancer. OXA-induced peripheral neurotoxicity (OXAIPN) is the major non-hematological dose-limiting toxicity of OXA-based chemotherapy and includes acute transient neurotoxic effects that appear soon after OXA infusion, and chronic non-length dependent sensory neuronopathy symmetrically affecting both upper and lower limbs in a stocking-and-glove distribution. [...]
2021 - 10.3390/jpm11070669
Journal of personalized medicine, Vol. 11 (july 2021)  
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2.
21 p, 1.0 MB Inhibition of the neuronal NFκB pathway attenuates bortezomib-induced neuropathy in a mouse model / Alé, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bruna, Jordi (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Calls, Aina (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Karamita, Maria (Hellenic Pasteur Institute) ; Haralambous, Sylva (Hellenic Pasteur Institute) ; Probert, Lesley (Hellenic Pasteur Institute) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Udina i Bonet, Esther (Universitat Autònoma de Barcelona. Institut de Neurociències)
© 2016 Elsevier B. V. Bortezomib is a proteasome inhibitor with a remarkable antitumor activity, used in the clinic as first line treatment for multiple myeloma. One hallmark of bortezomib mechanism of action in neoplastic cells is the inhibition of nuclear factor kappa B (NFκB), a transcription factor involved in cell survival and proliferation. [...]
2016 - 10.1016/j.neuro.2016.05.004
NeuroToxicology, Vol. 55 (2016) , p. 58-64  
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3.
11 p, 14.5 MB Fragment C Domain of Tetanus Toxin Mitigates Methamphetamine Neurotoxicity and Its Motor Consequences in Mice / Mendieta, Liliana (Instituto Cajal, Consejo Superior de Investigaciones Científicas, CSIC) ; Granado, Noelia (Instituto Cajal, Consejo Superior de Investigaciones Científicas, CSIC) ; Aguilera, José (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Tizabi, Yousef (Instituto Cajal, Consejo Superior de Investigaciones Científicas, CSIC) ; Moratalla, Rosario (Instituto Cajal, Consejo Superior de Investigaciones Científicas, CSIC) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
The C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) is a nontoxic peptide with demonstrated in vitro and in vivo neuroprotective effects against striatal dopaminergic damage induced by 1-methyl-4-phenylpyridinium and 6-hydoxydopamine, suggesting its possible therapeutic potential in Parkinson's disease. [...]
2016 - 10.1093/ijnp/pyw021
International journal of neuropsychopharmacology, Vol. 19 (march 2016)  
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4.
2 p, 311.9 KB Senescence in neurons : an open issue / Bruna, Jordi (Institut d'Investigació Biomèdica de Bellvitge) ; Calls, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Yuste, Victor J.. (Universitat Autònoma de Barcelona. Institut de Neurociències)
2021 - 10.18632/aging.203329
Aging (Albany NY), Vol. 13, Num. 13 (July 2021) , p. 16902-16903  
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5.
4 p, 209.1 KB Sigma-1 receptor : a new player in neuroprotection against chemotherapy-induced peripheral neuropathy / Bruna, Jordi (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Velasco, Roser (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Chemotherapy-induced peripheral neuropathy is a very frequent neurological complication in cancer. Oxaliplatin (OXA) is a platinum analogue used as a first-line agent in the treatment of colorectal cancer. [...]
2018 - 10.4103/1673-5374.232459
Neural Regeneration Research, Vol. 13 (may 2018) , p. 775-778  
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6.
18 p, 205.0 KB Taxane-Induced Peripheral Neurotoxicity / Velasco Fargas, Roser (Hospital Universitari de Bellvitge) ; Bruna, Jordi (Universitat Autònoma de Barcelona. Institut de Neurociències)
Taxane-derived agents are chemotherapy drugs widely employed in cancer treatment. Among them, paclitaxel and docetaxel are most commonly administered, but newer formulations are being investigated. Taxane antineoplastic activity is mainly based on the ability of the drugs to promote microtubule assembly, leading to mitotic arrest and apoptosis in cancer cells. [...]
2015 - 10.3390/toxics3020152
Toxics, Vol. 3 Núm. 2 (April 2015) , p. 152-169  
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7.
8 p, 744.1 KB Tritrichomonas foetus como agente etiológico de diarrea en el gato / Esteban, D.
Tritrichomonas foetus es un protozoo flagelado que, cuando parasita el colon del gato, puede causar diarrea crónica. Causante de patología reproductiva en bovinos, la T. foetus aislada en el gato posee un genotipo distinto al bovino. [...]
2010
Clínica veterinaria de pequeños animales, Vol. 30 Núm. 2 (2010) , p. 101-106  
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8.
12 p, 4.7 MB Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration : the role of p25/cyclin-dependent kinase 5 / Paoletti, Paola (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Vila, Ingrid (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Rifé, Maria (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Alberch i Vié, Jordi (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Ginés, Silvia (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Altered glutamatergic and dopaminergic signaling has been proposed as contributing to the specific striatal cell death observed in Huntington's disease (HD). However, the precise mechanisms by which mutant huntingtin sensitize striatal cells to dopamine and glutamate inputs remain unclear. [...]
2008 - 10.1523/JNEUROSCI.3237-08.2008
The Journal of neuroscience, Vol. 28 No. 40 (Oct. 2008) , p. 10090-10101  
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