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104 p, 1.6 MB |
Neurobehavioral and neurodevelopmental profiles of a heuristic genetic model of differential schizophrenia- and addiction-relevant features: The RHA vs. RLA rats
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Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Oliveras, Ignasi (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Cañete, Toni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Rio-Álamos, Cristóbal (Universidad Austral de Chile. Departamento de Psicologia) ;
Tapias-Espinosa, Carles (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sampedro-Viana, Daniel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sánchez-González, Ana (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sanna, Francesco (Universitá di Cagliari. Dipartimento di Scienze della vita e dell'ambiente) ;
Torrúbia, Rafael (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
González-Maeso, Javier (Virginia Commonwealth University School of Medicine. Department of Physiology and Biophysics) ;
Driscoll, Peter ;
Morón, Ignacio (Universidad de Granada. Departamento de Psicobiologia) ;
Torres, Carmen (Universidad de Jaén. Departamento de Psicología) ;
Aznar, Susana (Bispebjerg Copenhagen University Hospital) ;
Tobeña, Adolf 1950- (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corda, Maria G. (Universitá di Cagliari. Dipartimento di Scienze della vita e dell'ambiente) ;
Giorgi, Osvaldo (Universitá di Cagliari. Dipartimento di Scienze della vita e dell'ambiente) ;
Universitat Autònoma de Barcelona.
Institut de Neurociències
The Roman High- (RHA) and Low-(RLA) avoidance rat lines/strains were generated through bidirectional selective breeding for rapid (RHA) vs. extremely poor (RLA) two-way active avoidance acquisition. [...]
2021 -  10.1016/j.neubiorev.2021.09.042
Neuroscience and Biobehavioral Reviews, Vol. 131 (2021) , p. 597-617
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36 p, 1.6 MB |
Schizophrenia-like reduced sensorimotor gating in intact inbred and outbred rats is associated with decreased medial prefrontal cortex activity and volume
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Tapias-Espinosa, Carles (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Río-Álamos, Cristobal (Universidad Austral de Chile. Departamento de Psicologia) ;
Sánchez González, Ana (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Oliveras, Ignasi (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sampedro-Viana, Daniel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Castillo-Ruiz, Mª del Mar (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Cañete, Toni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Tobeña, Adolf 1950- (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Prepulse inhibition (PPI) of startle response is a measure of sensorimotor gating that is impaired in schizophrenia and in many other clinical conditions. Rat models using pharmacological or surgical strategies reveal that PPI is modulated by the cortico-striatal-pallido-thalamic (CSPT) circuit. [...]
2019 - 10.1038/s41386-019-0392-x
Neuropsychopharmacology, Vol. 44 Núm. 11 (2019) , p. 1975-1984
Neuropsychopharmacology, 2019
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23 p, 6.2 MB |
Acute Stress Induces Different Changes on the Expression of BDNF and trkB in the Mesocorticolimbic System of Two Lines of Rats Differing in Their Response to Stressors
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Serra, Maria Pina (University of Cagliari) ;
Sanna, Francesco (University of Cagliari) ;
Boi, Marianna (University of Cagliari) ;
Poddighe, Laura (University of Cagliari) ;
Secci, Lorenzo (University of Cagliari) ;
Trucas, Marcello (University of Cagliari) ;
Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corda, Maria Giuseppa (University of Cagliari) ;
Giorgi, Osvaldo (University of Cagliari) ;
Quartu, Marina (University of Cagliari)
The present work was undertaken to investigate the effects of acute forced swimming (FS) on the levels of brain-derived neurotrophic factor (BDNF) and tyrosine kinase receptor B (trkB) proteins in: the ventral tegmental area (VTA); the nucleus accumbens (Acb) shell and core compartments; and the anterior cingulate (ACg), prelimbic (PL) and infralimbic (IL) territories of the prefrontal cortex of genetic models of vulnerability (RLA, Roman low-avoidance rats) and resistance (RHA, Roman high-avoidance rats) to stress-induced depression. [...]
2022 - 10.3390/ijms232314995
International journal of molecular sciences, Vol. 23 (november 2022)
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8 p, 657.2 KB |
In vivo cholinergic basal forebrain degeneration and cognition in Parkinson's disease : Imaging results from the COPPADIS study
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Grothe, Michel (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Labrador-Espinosa, Miguel A. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Jesús Maestre, Silvia (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Macías-García, Daniel (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Adarmes-Gómez, A.D (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Carrillo, Fátima (Instituto de Biomedicina de Sevilla) ;
Iglesias Camacho, Elena (Instituto de Biomedicina de Sevilla) ;
Franco-Rosado, Pablo (Instituto de Biomedicina de Sevilla) ;
Roldán Lora, Florinda (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Martín-Rodríguez, Juan Francisco (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Aguilar Barberà, Miquel (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Pastor, Pau (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Escalante Arroyo, Sonia (Hospital de Tortosa Verge de la Cinta) ;
Soriano Vila, Berta (Institut Català de la Salut) ;
Cots-Foraster, Anna (Institut Català de la Salut) ;
Ruiz Martínez, Javier (Biodonostia Osasun Ikerketako Institutura (País Basc)) ;
Carrillo Padilla, Francisco (Hospital Universitario de Canarias (La Laguna)) ;
Pueyo Morlans, Mercedes (Hospital Universitario de Canarias (La Laguna)) ;
Gonzalez-Aramburu, Isabel (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Infante Ceberio, Jon (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Hernández Vara, Jorge (Hospital Universitari Vall d'Hebron) ;
Fàbregues-Boixar i Nebot, Oriol de (Hospital Universitari Vall d'Hebron) ;
de Deus Fonticoba, Teresa (Complejo Hospitalario Universitario de Ferrol) ;
Pascual-Sedano, Berta María (Institut d'Investigació Biomèdica Sant Pau) ;
Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Martínez-Martín, Pablo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Santos García, Diego (Complejo Hospitalario Universitario de A Coruña) ;
Mir, Pablo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas)
Introduction: We aimed to assess associations between multimodal neuroimaging measures of cholinergic basal forebrain (CBF) integrity and cognition in Parkinson's disease (PD) without dementia. Methods: The study included a total of 180 non-demented PD patients and 45 healthy controls, who underwent structural MRI acquisitions and standardized neurocognitive assessment through the PD-Cognitive Rating Scale (PD-CRS) within the multicentric COPPADIS-2015 study. [...]
2021 - 10.1016/j.parkreldis.2021.05.027
Parkinsonism and Related Disorders, Vol. 88 (july 2021) , p. 68-75
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17 p, 1.4 MB |
A Randomized Trial of Deep Brain Stimulation to the Subcallosal Cingulate and Nucleus Accumbens in Patients with Treatment-Refractory, Chronic, and Severe Anorexia Nervosa : Initial Results at 6 Months of Follow Up
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Villalba Martínez, Gloria (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Justicia, Azucena (Hospital del Mar (Barcelona, Catalunya)) ;
Salgado, Purificación (Hospital del Mar (Barcelona, Catalunya)) ;
Ginés, José María (Hospital del Mar (Barcelona, Catalunya)) ;
Guardiola, Rocío (Hospital del Mar (Barcelona, Catalunya)) ;
Cedrón, Carlos (Hospital del Mar (Barcelona, Catalunya)) ;
Polo, María (Hospital del Mar (Barcelona, Catalunya)) ;
Delgado Martínez, Ignacio (Hospital del Mar (Barcelona, Catalunya)) ;
Medrano, Santiago (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Manero, Rosa María (Hospital del Mar (Barcelona, Catalunya)) ;
Conesa, Gerardo (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Faus, Gustavo (Instituto de Trastornos Alimentarios (ITA)) ;
Grau Touriño, Antoni (Instituto de Trastornos Alimentarios (ITA)) ;
Elices, M (Centro de Investigación Biomédica en Red de Salud Mental) ;
Pérez Solà, Víctor (Hospital del Mar (Barcelona, Catalunya))
Background: The main objective of this study was to assess the safety and efficacy of deep brain stimulation (DBS) in patients with severe anorexia nervosa (AN). Methods: Eight participants received active DBS to the subcallosal cingulate (SCC) or nucleus accumbens (NAcc) depending on comorbidities (affective or anxiety disorders, respectively) and type of AN. [...]
2020 - 10.3390/jcm9061946
Journal of clinical medicine, Vol. 9 (june 2020)
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15 p, 1.2 MB |
The Bed Nucleus of the Stria Terminalis as a Brain Correlate of Psychological Inflexibility in Fibromyalgia
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Feliu-Soler, Albert (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Sanabria-Mazo, Juan P.. (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Fayed, Nicolás (Grup Quirónsalud (Barcelona, Catalunya)) ;
Stephan-Otto, Christian (Institut de Recerca Sant Joan de Déu) ;
Núñez, Christian (Institut de Recerca Sant Joan de Déu) ;
Soriano-Mas, Carles (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Luciano, Juan V. (Parc Sanitari Sant Joan de Déu. Unitat de Docència, Recerca i Innovació) ;
Martínez-Zalacaín, Ignacio (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Pérez-Aranda, Adrián (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Borràs, Xavier (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Andrés Rodríguez, Laura (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació)
This study explored the brain structural correlates of psychological flexibility (PF) as measured with the Psychological Inflexibility in Pain Scale (PIPS) in patients with fibromyalgia (FM). Structural magnetic resonance imaging data from 47 FM patients were used to identify Gray Matter Volume (GMV) alterations related to PIPS scores. [...]
MDPI, 2020 - 10.3390/jcm9020374
Journal of clinical medicine, Vol. 9 Núm. 2 (2020) , p. 374
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12 p, 1.7 MB |
Looking at the past and heading to the Future : Meeting summary of the 6th European Workshop on Plant Chromatin 2019 in Cologne, Germany
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Moreno Romero, Jordi (Centre de Recerca en Agrigenòmica) ;
Probst, Aline V. (Centre National de la Recherche Scientifique (França)) ;
Trindade, Inês (University of Potsdam. Institute for Biochemistry and Biology (Germany)) ;
Kalyanikrishna (Freie Universität Berlin) ;
Engelhorn, Julia (Max Planck Institute for Plant Breeding Research (Germany)) ;
Farrona, S. (Ryan Institute. Plant and AgriBiosciences Centre (Ireland))
In June 2019, more than a hundred plant researchers met in Cologne, Germany, for the 6th European Workshop on Plant Chromatin (EWPC). This conference brought together a highly dynamic community of researchers with the common aim to understand how chromatin organization controls gene expression, development, and plant responses to the environment. [...]
2020 - 10.3389/fpls.2019.01795
Frontiers in plant science, Vol. 10 (February 2020) , art. 1795
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