Results overview: Found 16 records in 0.02 seconds.
Articles, 9 records found
Research literature, 7 records found
Articles 9 records found  
1.
10 p, 1.2 MB A single cysteine post-translational oxidation suffices to compromise globular proteins kinetic stability and promote amyloid formation / Marinelli, Patrizia (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Navarro, Susanna (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Graña Montes, Ricardo (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Bañó-Polo, Manuel (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Fernández Gallegos, Ma. Rosario (María Rosario) (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Papaleo, Elena (Kræftens Bekæmpelse) ; Ventura i Zamora, Salvador (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Oxidatively modified forms of proteins accumulate during aging. Oxidized protein conformers might act as intermediates in the formation of amyloids in age-related disorders. However, it is not known whether this amyloidogenic conversion requires an extensive protein oxidative damage or it can be promoted just by a discrete, localized post-translational modification of certain residues. [...]
2017 - 10.1016/j.redox.2017.10.022
Redox Biology, Vol. 14 (April 2018) , p. 566-575  
2.
13 p, 1.1 MB Protein aggregation into insoluble deposits protects from oxidative stress / Carija, Anita (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Navarro, Susanna (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Sánchez de Groot, Natalia (Centre de Regulació Genòmica) ; Ventura i Zamora, Salvador (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Protein misfolding and aggregation have been associated with the onset of neurodegenerative disorders. Recent studies demonstrate that the aggregation process can result in a high diversity of protein conformational states, however the identity of the specific species responsible for the cellular damage is still unclear. [...]
2017 - 10.1016/j.redox.2017.03.027
Redox Biology, Vol. 12 (Aug. 2017) , p. 699-711  
3.
24 p, 5.9 MB Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease / Unzeta López, Mercedes (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Esteban, Gerard (Trinity College Dublin. School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute) ; Bolea Tomás, Irene (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Fogel, Wieslawa A. (Medical University of Lodz. Department of Hormone Biochemistry) ; Ramsay, Rona R. (University of St Andrews. Biomedical Sciences Research Complex) ; Youdim, Moussa B. H. (Ruth and Bruce Rappaport Faculty of Medicine. Department of Pharmacology) ; Tipton, Keith F. (Trinity College Dublin. School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute) ; Marco-Contelles, José (Spanish National Research Council. Institute of General Organic Chemistry) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
HIGHLIGHTS Alzheimer's disease (AD), the most common form of adult onset dementia, is an age-related neurodegenerative disorder characterized by progressive memory loss, decline in language skills, and other cognitive impairments. [...]
2016 - 10.3389/fnins.2016.00205
Frontiers in Neuroscience, Vol. 10 (May 2016) , art. 205  
4.
9 p, 1.0 MB Oral chondroitin sulfate and prebiotics for the treatment of canine Inflammatory Bowel Disease : a randomized, controlled clinical trial / Segarra, Sergi ; Martínez-Subiela, Silvia ; Cerdà-Cuéllar, Marta (Fundació Centre de Recerca en Sanitat Animal) ; Martínez-Puig, Daniel ; Muñoz-Prieto, Alberto ; Rodríguez-Franco, Fernando ; Rodríguez-Bertos, Antonio ; Allenspach, Karin ; Velasco, Alfonso ; Cerón, José
Canine inflammatory bowel disease (IBD) is a chronic enteropathy of unknown etiology, although microbiome dysbiosis, genetic susceptibility, and dietary and/or environmental factors are hypothesized to be involved in its pathogenesis. [...]
2016 - 10.1186/s12917-016-0676-x
BMC Veterinary Research, Vol. 12 (march 2016)  
5.
9 p, 626.3 KB Proteome response at the edge of protein aggregation / Sanchez de Groot, Natalia (MRC Laboratory of Molecular Biology) ; Gomes, Ricardo A. (Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier) ; Villar Pique, Anna (University Medical Centre Göottingen. Department of Neurodegeneration and Restorative Research) ; Madan Babu, M. (MRC Laboratory of Molecular Biology) ; Varela Coelho, Ana (Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier) ; Ventura i Zamora, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Proteins adopt defined structures and are crucial to most cellular functions. Their misfolding and aggregation is associated with numerous degenerative human disorders such as type II diabetes, Huntington's or Alzheimer's diseases. [...]
2015 - 10.1098/rsob.140221
Open biology, Vol. 5, issue 2 (Feb. 2015) , art. 140221  
6.
9 p, 774.4 KB Aging and radiation : bad companions / Hernández Garcia, Laia (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Terradas Ill, Mariona (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Camps, Jordi (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Martín Flix, Marta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Tusell Padrós, Laura (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Genescà i Garrigosa, Anna (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Aging involves a deterioration of cell functions and changes that may predispose the cell to undergo an oncogenic transformation. The carcinogenic risks following radiation exposure rise with age among adults. [...]
2015 - 10.1111/acel.12306
Aging Cell, Vol. 14, Issue 2 (April 2015) , p. 153-161  
7.
12 p, 278.9 KB Oxidative folding in the mitochondrial intermembrane space in human health and disease / Fraga, Hugo (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Ventura i Zamora, Salvador (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Oxidative folding in the mitochondrial intermembrane space (IMS) is a key cellular event associated with the folding and import of a large and still undetermined number of proteins. This process is catalyzed by an oxidoreductase, Mia40 that is able to recognize substrates with apparently little or no homology. [...]
2013 - 10.3390/ijms14022916
International journal of molecular sciences, Vol. 14, issue 2 (Jan. 2013) , p. 2916-2927  
8.
11 p, 2.1 MB Transient Mesenteric Ischemia Leads to Remodeling of Rat Mesenteric Resistance Arteries / Caracuel Cano, Laura (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Jiménez-Altayó, Francesc (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Romo, Mónica (Universitat Autònoma de Barcelona. Departament de Farmacologia, Terapèutica i Toxicología) ; Márquez-Martín, Ana (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Dantas, Ana P. (Cardiologia Experimental, Institut Clínic del Tòrax, Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Vila, Elisabet (Universitat Autònoma de Barcelona. Institut de Neurociències)
Mesenteric ischemia/reperfusion (I/R) is associated with high rates of morbidity and mortality. We studied the effect of mesenteric I/R on structural and mechanical properties of rat mesenteric resistance artery (MRA) that, once disrupted, might impact the outcome of this devastating clinical condition. [...]
2012 - 10.3389/fphys.2011.00118
Frontiers in Physiology, Vol. 2 (january 2012)  
9.
11 p, 2.1 MB Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle / Tainã Figueiredo Cardos (Centre de Recerca en Agrigenòmica) ; Quintanilla Aguado, Raquel (Institut de Recerca i Tecnologia Agroalimentàries) ; Tibau, Joan (Institut de Recerca i Tecnologia Agroalimentàries) ; Gil, Marta (Institut de Recerca i Tecnologia Agroalimentàries) ; Mármol-Sánchez, Emilio (Centre de Recerca en Agrigenòmica) ; González-Rodríguez, Olga (Capes Foundation) ; González Prendes, Rayner (Centre de Recerca en Agrigenòmica) ; Amills i Eras, Marcel (Centre de Recerca en Agrigenòmica)
Background: The genetic basis of muscle fat deposition in pigs is not well known. So far, we have only identified a limited number of genes involved in the absorption, transport, storage and catabolism of lipids. [...]
2017 - 10.1186/s12864-017-3986-x
BMC Genomics, Vol. 18 (Aug. 2017) , art. 603  

Research literature 7 records found  
1.
184 p, 4.3 MB Determinación del estrés oxidativo en plasma seminal como parámetro diagnóstico en pacientes con cáncer de próstata. / Barrio Muñoz, Miriam, autor. ; Navarro Soto, Salvador, supervisor acadèmic. ; Prats López, Joan, supervisor acadèmic. ; Universitat Autònoma de Barcelona. Departament de Cirurgia.
[Barcelona] : Universitat Autònoma de Barcelona, 2017.  
2.
1 p, 660.4 KB Controversial effect of vitamin E supplementation in subjects with Down syndrome / Samarra Mestre, Iris ; Jiménez Altayó, Francesc, dir. (Universitat Autònoma de Barcelona.Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Ciències Biomèdiques [832]  
3.
1 p, 367.7 KB Hibiscus sabdariffa : a potential strategy to decrease aging-induced cardiovascular risk? / Farré Alins, Víctor ; Jiménez Altayó, Francesc, dir. (Universitat Autònoma de Barcelona.Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Ciències Biomèdiques [832]  
4.
1 p, 910.5 KB Reactive oxygen species generated in a chronic consumption of alcohol : pathogenesis in the liver / Fosch i Masllovet, Anna ; Parés i Casasampera, Xavier, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Ciències Biomèdiques [832]  
5.
1 p, 410.9 KB DJ-1, a possible therapeutic target against Parkinson's disease / Oliva Vilarnau, Núria ; Yuste Mateos, Víctor J., (Víctor José), dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Biotecnologia [815]  
6.
122 p, 2.1 MB Effects of oxidative stress on plasma membrane fluidity: biological consequences / de la Haba Fonteboa, Carlos ; Martínez, Paz, dir. ; Morros, Antoni, dir. ; Palacio, José Ramón, dir. ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
El estrés oxidativo (OS) es característico de muchas enfermedades y se produce cuando hay un desequilibrio entre oxidantes y antioxidantes, lo cual favorece un estado oxidativo que genera especies reactivas de oxígeno y de nitrógeno. [...]
Oxidative stress is present in many diseases and it is produced in cells when an imbalance between oxidants and antioxidants occurs, favoring an oxidant status which produce reactive oxygen and nitrogen species. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2015  
7.
1 p, 8.3 MB The role of astrocytes in stroke / Abad Puig, Marta ; Masgrau Juanola, Roser, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Graduat o Graduada en Bioquímica [814]  

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