Results overview: Found 5 records in 0.02 seconds.
Articles, 4 records found
Research literature, 1 records found
Articles 4 records found  
1.
8 p, 500.8 KB Relative bioavailability of three formulations of galunisertib administered as monotherapy in patients with advanced or metastatic cancer / Gueorguieva, Ivelina (Eli Lilly and Company (United Kingdom)) ; Cleverly, Ann (Eli Lilly and Company (United Kingdom)) ; Desaiah, Durisala (Eli Lilly and Company (USA)) ; Azaro, Analia (Hospital Universitari Vall Hebron) ; Seoane Suárez, Joan (Vall Hebron. Institut d'Oncologia (VHIO)) ; Braña, Irene (Hospital Universitari Vall Hebron) ; Sicart, Elisabet (Hospital Universitari Vall Hebron) ; Miles, Colin (Eli Lilly and Company (United Kingdom)) ; Lahn, Michael M (Eli Lilly and Company (USA)) ; Mitchell, Malcolm I (Eli Lilly and Company (USA)) ; Rodón Ahnert, Jordi (Institut d'Oncologia de la Vall Hebron (VHIO)) ; Universitat Autònoma de Barcelona
Galunisertib (LY2157299 monohydrate), an inhibitor of the transforming growth factor β (TGFβ) pathway, is currently under investigation in several clinical trials involving multiple tumor types. The primary objective of this study was to assess relative bioavailability of two new galunisertib formulations developed using the roller compaction (RC) dry-milled (RCD) and RC slurry-milled (RCS) processes, compared with the existing formulation developed using the high-sheer wet granulation (HSWG) process. [...]
2016 - 10.7573/dic.212303
Drugs in Context, Vol. 5 (December 2016) , art. 201303  
2.
10 p, 1.6 MB Etravirine pharmacokinetics in HIV-infected pregnant women / Mulligan, Nikki (University of California (Estats Units d'Amèrica)) ; Schalkwijk, Stein (Radboud University Nijmegen Medical Centre (Nijmegen, Països Baixos)) ; Best, Brookie M. (University of California (Estats Units d'Amèrica)) ; Colbers, Angela (Radboud University Nijmegen Medical Centre (Nijmegen, Països Baixos)) ; Wang, Jiajia (Harvard School of Public Health (Boston, Estats Units d'Amèrica)) ; Capparelli, Edmund V. (University of California (Estats Units d'Amèrica)) ; Moltó Marhuenda, José ((Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Stek, Alice M. (University of Southern California. School of Medicina (Estats Units d'Amèrica)) ; Taylor, Graham (Imperial College Healthcare National Health Service Trust (Londres, Regne Unit)) ; Smith, Elizabeth (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ; Hidalgo Tenorio, Carmen (Hospital Virgen de las Nieves (Granada, Andalusia)) ; Chakhtoura, Nahida (Eunice Kennedy Shriver National Institute of Child Health and Human Development (Bethesda, Estats Units d'Amèrica)) ; Van Kasteren, Marjo (Saint Elisabeth Hospital (Tilburg, Països Baixos)) ; Fletcher, Courtney V. (University of Nebraska Medical Center (Omaha, Estats Units d'Amèrica)) ; Mirochnick, Mark (Boston University School of Medicine (Estats Units d'Amèrica)) ; Burger, David (Radboud University Nijmegen Medical Centre (Nijmegen, Països Baixos)) ; PANNA Network ; IMPAACT Network
BACKGROUND: The study goal was to describe etravirine pharmacokinetics during pregnancy and postpartum in HIV-infected women. METHODS: IMPAACT P1026s and PANNA are on-going, non-randomized, open-label, parallel-group, multi-center phase-IV prospective studies in HIV-infected pregnant women. [...]
2016 - 10.3389/fphar.2016.00239
Frontiers in Pharmacology, Vol. 7 Núm. 239 (August 2016)  
3.
17 p, 2.5 MB DCE@urLAB : a dynamic contrast-enhanced MRI pharmacokinetic analysis tool for preclinical data / Ortuño, Juan E. (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Saragosssa, Aragó)) ; Ledesma Carbayo, María J. (Universidad Politécnica de Madrid. Departamento de Ingeniería Electrónica) ; Simões, Rui V. (Universitat de Barcelona) ; Candiota Silveira, Ana Paula (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Arús i Caraltó, Carles (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Santos, Andrés (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Saragosssa, Aragó))
Background: DCE@urLAB is a software application for analysis of dynamic contrast-enhanced magnetic resonance imaging data (DCE-MRI). The tool incorporates a friendly graphical user interface (GUI) to interactively select and analyze a region of interest (ROI) within the image set, taking into account the tissue concentration of the contrast agent (CA) and its effect on pixel intensity. [...]
2013 - 10.1186/1471-2105-14-316
BMC Bioinformatics, Vol. 14, N. 316 (November 2013) , p. 1-17  
4.
14 p, 606.8 KB Cafeína: un nutriente, un fármaco, o una droga de abuso / Pardo Lozano, Ricardo (Hospital del Mar. Institut Municipal d'Investigació Mèdica) ; Álvarez García, Yolanda ; Barral Tafalla, Diego ; Farré Albaladejo, Magí (Hospital del Mar. Institut Municipal d'Investigació Mèdica)
El café, el té, el chocolate y los refrescos de cola son las principales fuentes de cafeína, que es consumida en casi todas las edades y estratos socioeconómicos. La cafeína es un antagonista competitivo de los receptores adenosínicos del SNC. [...]
Coffee, tea, chocolate and caffeinated drinks are the main sources of caffeine, which is consumed in almost all ages and socioeconomic levels. Caffeine acts as a non-selective adenosine receptor antagonist in the central nervous system. [...]

2007
Adicciones: Revista de socidrogalcohol, Vol. 19, Núm. 3 (2007) , p. 225-238  

Research literature 1 records found  
1.
1 p, 2.1 MB Immunoliposomes state of the art : pharmacokinetics of a novel drug delivery system for cancer treatment / García Pagès, Esther ; Vivas Sabido, Nuria María, dir. (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Ciències Biomèdiques [832]  

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