Resultats globals: 10 registres trobats en 0.02 segons.
Articles, 9 registres trobats
Documents de recerca, 1 registres trobats
Articles 9 registres trobats  
1.
20 p, 2.2 MB Role of muscle IL-6 in gender-specific metabolism in mice / Molinero Egea, María Amalia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Fernandez-Perez, Antonio (Universidad Autonoma de Madrid. Centro de Investigacion Biomedica en Red de Diabetes y Enfermedades metabólicas asociadas CIBERDEM) ; Mogas Barcons, Aina (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Giralt Carbonell, Mercedes (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Comes Orpinell, Gemma (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Fernandez Gayol, Olaya (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Vallejo, Mario (Universidad Autonoma de Madrid (CSIC-UAM). Centro de Investigacion Biomedica en Red de Diabetes y Enfermedades metabólicas asociadas CIBERDEM.) ; Hidalgo Pareja, Juan (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
The aim of the present work was to further explore the physiological roles of muscle-derived IL-6. Adult-floxed and conditional skeletal muscle IL-6 knock out male and female mice were used to study energy expenditure (indirect calorimetry at rest and during treadmill exercise, and body temperature cycle during the light phase) and energy intake (response to fast/ refeeding). [...]
2017 - 10.1371/journal.pone.0173675
PLoS ONE, Vol. 12, Núm. 3 (March 2017) , art. e173675  
2.
13 p, 5.1 MB Conjecture regarding posttranslational modifications to the Arabidopsis type I proton-pumping pyrophosphatase (AVP1) / Pizzio, Gaston A. (Centre de Recerca en Agrigenòmica) ; Hirschi, Kendal D. (Children’s Nutrition Research Center,) ; Gaxiola, Roberto A. (Arizona State University. School of Life Sciences)
Agbiotechnology uses genetic engineering to improve the output and value of crops. Altering the expression of the plant Type I Proton-pumping Pyrophosphatase (H+-PPase) has already proven to be a useful tool to enhance crop productivity. [...]
2017 - 10.3389/fpls.2017.01572
Frontiers in plant sciences, Vol. 8 (Set. 2017) , art. 1572  
3.
11 p, 1.9 MB Soluble oligomers of amyloid-beta peptide disrupt membrane trafficking of alpha-amino-3-hydroxy-5-methylisoxazole-4 propionic acid receptor (AMPAR) contributing to early synapse dysfunction / Miñano Molina, Alfredo Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències) ; España Agustí, Judit (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Martín, Elsa (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Barneda Zahonero, Bruna (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Fadó Andrés, Rut (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Solé Piñol, Montserrat (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Trullas i Oliva, Ramon (Centro de Investigación Biomedica en Red sobre Enfermedades Neurodegenerativas (CIBERNED)) ; Saura Antolín, Carlos A. (Carlos Alberto) (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Rodríguez Álvarez, José (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
β-Amyloid (Aβ), a peptide generated from the amyloid precursor protein, is widely believed to underlie the pathophysiology of Alzheimer disease (AD). Emerging evidences suggest that soluble Aβ oligomers adversely affect synaptic function, leading to cognitive failure associated with AD. [...]
2011 - 10.1074/jbc.M111.227504
The Journal of biological chemistry, Vol. 286, No. 31 (2011) , p. 543-557  
4.
19 p, 9.0 MB Osmostress-Induced Apoptosis in Xenopus Oocytes : Role of Stress Protein Kinases, Calpains and Smac/DIABLO / Ben Messaoud, Nabil (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Yue, Jicheng (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Valent, Daniel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Katzarova, Ilina (Universitat Autònoma de Barcelona. Institut de Neurociències) ; López Blanco, José Manuel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Hyperosmotic shock induces cytochrome c release and capase-3 activation in Xenopus oocytes, but the regulators and signaling pathways involved are not well characterized. Here we show that hyperosmotic shock induces rapid calpain activation and high levels of Smac/DIABLO release from the mitochondria before significant amounts of cytochrome c are released to promote caspase-3 activation. [...]
2015 - 10.1371/journal.pone.0124482
PLoS one, Vol. 10, Num. 4 (2015) , p. 1-19  
5.
15 p, 2.0 MB Basic Properties of the p38 Signaling Pathway in Response to Hyperosmotic Shock / Ben Messaoud, Nabil (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Katzarova, Ilina (Universitat Autònoma de Barcelona. Institut de Neurociències) ; López Blanco, José Manuel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Some properties of signaling systems, like ultrasensitivity, hysteresis (a form of biochemical memory), and all-or-none responses at a single cell level, are important to understand the regulation of irreversible processes. [...]
2015 - 10.1371/journal.pone.0135249
PLoS one, Vol. 10, Num. 9 (September 2015) , p. 1-15  
6.
24 p, 5.5 MB GSK3β inhibition promotes synaptogenesis in Drosophila and mammalian neurons / Cuesto, Germán (Centro de Investigación Biomédica de La Rioja (Logronyo)) ; Jordán-Álvarez, Sheila (Instituto Cajal (Madrid, Espanya)) ; Enríquez-Barreto, Lilian (Centro de Investigación Biomédica de La Rioja (Logronyo)) ; Ferrús, Alberto (Instituto Cajal (Madrid, Espanya)) ; Morales, Miguel (Centro de Investigación Biomédica de La Rioja (Logronyo)) ; Acebes, Ángel (Instituto Cajal (Madrid, Espanya))
The PI3K-dependent activation of AKT results in the inhibition of GSK3β in most signaling pathways. These kinases regulate multiple neuronal processes including the control of synapse number as shown for Drosophila and rodents. [...]
2015 - 10.1371/journal.pone.0118475
PLoS One, Vol. 10 Núm. 3 (March 2015) , e0118475  
7.
8 p, 1.1 MB Role of IL-6 in Exercise Training- and Cold-Induced UCP1 Expression in Subcutaneous White Adipose Tissue / Knudsen, Jakob G. (University of Copenhagen. Department of Biology) ; Murholm, Maria (University of Copenhagen. Department of Biology) ; Carey, Andrew L. (Baker IDI Heart and Diabetes Institute (Melbourne, Austràlia)) ; Biensø, Rasmus S. (University of Copenhagen. Department of Biology) ; Basse, Astrid L. (University of Copenhagen.Departament de Biologia) ; Allen, Tamara L (Baker IDI Heart and Diabetes Institute (Melbourne, Austràlia)) ; Hidalgo Pareja, Juan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Kingwell, Bronwyn A. (Baker IDI Heart and Diabetes Institute (Melbourne, Austràlia)) ; Febbraio, Mark A. (Baker IDI Heart and Diabetes Institute (Melbourne, Austràlia)) ; Hansen, Jacob B. (University of Copenhagen. Department of Biology) ; Pilegaard, Henriette (University of Copenhagen. Department of Biology)
Expression of brown adipose tissue (BAT) associated proteins like uncoupling protein 1 (UCP1) in inguinal WAT (iWAT) has been suggested to alter iWAT metabolism. The aim of this study was to investigate the role of interleukin-6 (IL-6) in exercise training and cold exposure-induced iWAT UCP1 expression. [...]
2014 - 10.1371/journal.pone.0084910
PLoS one, Vol. 9 Issue 1 (January 2014) , p. e84910  
8.
9 p, 1.4 MB Prostaglandin E2 Prevents Hyperosmolar-Induced Human Mast Cell Activation through Prostanoid Receptors EP2 and EP4 / Torres Atencio, Ivonne Marisol (Universidad de Panamá. Facultad de Medicina) ; Ainsua-Enrich, Erola (Institut d’Investigacions Biomèdiques August Pi i Sunyer) ; Mora Pérez, Fernando de (Universitat Autònoma de Barcelona. Departament de Farmacologia, Terapèutica i Toxicologia) ; Picado Valles, César (Institut d’Investigacions Biomèdiques August Pi i Sunyer) ; Martín Castillo, Margarita (Institut d’Investigacions Biomèdiques August Pi i Sunyer)
Background: Mast cells play a critical role in allergic and inflammatory diseases, including exercise-induced bronchoconstriction (EIB) in asthma. The mechanism underlying EIB is probably related to increased airway fluid osmolarity that activates mast cells to the release inflammatory mediators. [...]
2014 - 10.1371/journal.pone.0110870
PLoS one, Vol. 9, Issue 10 (October 2014) , p.e110870  
9.
14 p, 2.7 MB KAP degradation by calpain is associated with CK2 phosphorylation and provides a novel mechanism for cyclosporine A-induced proximal tubule injury. / Tornavaca i Làzaro, Olga (Vall d'Hebron Hospitals) ; Sarró Tauler, Eduard (Vall d'Hebron Hospitals) ; Pascual, Gloria (Vall d'Hebron Hospitals) ; Bardaji, Beatriz (Vall d'Hebron Hospitals) ; Montero, M. Ángeles (Vall d'Hebron Hospitals) ; Salcedo, M. Teresa (Vall d'Hebron Hospitals) ; Plana i Coll, Maria (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; López Hellín, Juan (Vall d'Hebron Hospitals) ; Itarte, Emili (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Meseguer Navarro, Anna (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
The use of cyclosporine A (CsA) is limited by its severe nephrotoxicity that includes reversible vasoconstrictor effects and proximal tubule cell injury, the latter associated whith chronic kidney disease progression. [...]
2011 - 10.1371/journal.pone.0025746
PLoS one, Vol. 6, Issue 9 (September 2011) , p. e25746  

Documents de recerca 1 registres trobats  
1.
211 p, 2.4 MB Linker histone post-translational modifications and effects of phosphorylation on secondary structure and chromatin aggregation / Lopez Ramos, Rita ; Ponte Marull, Immaculada, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Roque Córdova, Alicia, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Les histones linker juguen un paper important en l'organització i manteniment de la cromatina en estructures d'ordre superior i en la regulació transcripcional. La histona H1 en vertebrats té una estructura característica en tres dominis: un domini N-terminal curt i flexible; un domini globular central; i un domini C-terminal llarg. [...]
Linker histones play an important role in establishing and maintaining chromatin higher-order structure and in transcriptional regulation. Histone H1 in vertebrates has a characteristic three-domain structure consisting of a short flexible N-terminal domain, a central globular domain and a long C-terminal domain. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  

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