Home > Search Results: Photodynamic therapy
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Articles, 2 records found
Articles 2 records found  
1.
15 p, 3.6 MB Light excitation of gold Nanorod-Based hybrid nanoplatforms for simultaneous bimodal phototherapy / Arellano, Lilia G. (Universidade de Santiago de Compostela. Departamento de Física de Partículas) ; Villar-Alvarez, Eva (Institut Català de Nanociència i Nanotecnologia) ; Velasco, Brenda (Universidade de Santiago de Compostela. Departamento de Física de Partículas) ; Domínguez-Arca, Vicente (Universidade de Santiago de Compostela. Departamento de Física de Partículas) ; Prieto, Gerardo (Universidade de Santiago de Compostela. Departamento de Física Aplicada) ; Cambón, Adriana (Universidade de Santiago de Compostela. Departamento de Física de Partículas) ; Barbosa, Silvia (Universidade de Santiago de Compostela. Departamento de Física de Partículas) ; Taboada, Pablo (Universidade de Santiago de Compostela. Departamento de Física de Partículas)
In this work, we developed a hybrid nanosystem able to simultaneously combine its potential as a photodynamic (PDT) and plasmonic photothermal (PPTT) therapeutic agent to kill malignant cells. To do that, AuNRs were functionalized by means of the layer-by-layer (LbL) assembly technique using alternating layers of anionic poly(styrene sulfonate) (PSS) and cationic poly-L-lysine (PLL) as polyelectrolytes (PEs), and an outer final layer of hyaluronic acid (HA) to provide the hybrid particles with both sufficient colloidal stability and targeting ability to tumoral cells overexpressing CD44 receptors. [...]
2023 - 10.1016/j.molliq.2023.121511
Journal of Molecular Liquids, Vol. 377 (May 2023) , art. 121511  
Detailed record - Creative Commons
2.
10 p, 2.3 MB A new porphyrin for the preparation of functionalized water-soluble gold nanoparticles with low intrinsic toxicity / Penon, Oriol (Universitat de Barcelona. Departament de Farmacologia i Química Terapèutica) ; Patiño, Tania (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Barrios, Leonardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Nogués, C. (Carme) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Amabilino, David B. (Institut de Ciència de Materials de Barcelona) ; Wurst, Klaus (Institut für Anorganische Chemie) ; Pérez García, Lluïsa (Universitat de Barcelona. Departament de Farmacologia i Química Terapèutica)
A potential new photosensitizer based on a dissymmetric porphyrin derivative bearing a thiol group was synthesized. 5-[4-(11-Mercaptoundecyloxy)-phenyl-10,15,20-triphenylporphyrin (PR-SH) was used to functionalize gold nanoparticles in order to obtain a potential drug delivery system. [...]
2015 - 10.1002/open.201402092
ChemistryOpen, Vol. 4, issue 2 (April 2015) , p. 127-136  
Detailed record - Creative Commons

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