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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
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Zhang, Qian (St. Rockefeller University) ;
Liu, Zhiyong (Rockefeller University) ;
Moncada-Velez, Marcela (Rockefeller University) ;
Chen, Jie (Rockefeller University) ;
Ogishi, Masato (Rockefeller University) ;
Bigio, Benedetta (Rockefeller University) ;
Yang, Rui (Rockefeller University) ;
Arias, Andrés Augusto (Universidad de Antioquia) ;
Zhou, Qinhua (Rockefeller University) ;
Han, Ji Eun (Rockefeller University) ;
Ugurbil, Aileen Camille (Rockefeller University) ;
Zhang, Peng (Rockefeller University) ;
Rapaport, Franck (Rockefeller University) ;
Li, Juan (Rockefeller University) ;
Spaan, András N. (University Medical Center Utrecht) ;
Boisson, Bertrand (University of Paris) ;
Boisson-Dupuis, S. (University of Paris) ;
Bustamante, J. (Necker Hospital for Sick Children) ;
Puel, A. (University of Paris) ;
Ciancanelli, Michael J (Turnstone Biologics) ;
Zhang, Shen-Ying (University of Paris) ;
Béziat, V. (University of Paris) ;
Jouanguy, E. (University of Paris) ;
Abel, Laurent (INSERM U1163. University of Paris) ;
Cobat, A. (University of Paris) ;
Casanova, Jean-Laurent (Rockefeller University) ;
Bastard, Paul (University of Paris) ;
Korol, Cecilia (Necker Hospital for Sick Children, Paris) ;
Rosain, Jérémie (University of Paris) ;
Philippot, Q. (APHP Tenon Hospital) ;
Chbihi, Marwa (University of Paris. Imagine Institute) ;
Lorenzo, L. (University of Paris. Imagine Institute) ;
Bizien, L. (University of Paris. Imagine Institute) ;
Neehus, A. L. (University of Paris. Imagine Institute) ;
Kerner, G. (University of Paris. Imagine Institute) ;
Seeleuthner, Y. (University of Paris. Imagine Institute) ;
Manry, J. (University of Paris. Imagine Institute) ;
Le Voyer, T. (University of Paris. Imagine Institute) ;
Boisson, Bertrand (University of Paris. Imagine Institute) ;
Boisson-Dupuis, S. (University of Paris. Imagine Institute) ;
Bustamante, J. (Necker Hospital for Sick Children. AP-HP) ;
Puel, A. (University of Paris. Imagine Institute) ;
Zhang, S. Y. (University of Paris. Imagine Institute) ;
Béziat, V. (University of Paris. Imagine Institute) ;
Jouanguy, E. (University of Paris) ;
Abel, Laurent (University of Paris) ;
Cobat, A. (University of Paris) ;
Bastard, Paul (University of Paris) ;
Rosain, J. (University of Paris) ;
Philippot, Q. (APHP Tenon Hospital) ;
Chbihi, M. (University of Paris) ;
Lorenzo, L. (University of Paris) ;
Bizien, L. (University of Paris) ;
Neehus, A. L. (University of Paris) ;
Kerner, G. (University of Paris) ;
Seeleuthner, Y. (University of Paris) ;
Manry, J. (University of Paris) ;
Le Voyer, T. (University of Paris) ;
Boisson, Bertrand (University of Paris) ;
Boisson-Dupuis, S. (University of Paris) ;
Bustamante, J. (Necker Hospital for Sick Children) ;
Puel, A. (University of Paris) ;
Zhang, S. Y. (University of Paris) ;
Béziat, Vivien (University of Paris) ;
Jouanguy, Emmanuelle (University of Paris) ;
Abel, Laurent (INSERM U1163. University of Paris) ;
Cobat, Aurélie (University of Paris) ;
Le Pen, Jérémie (Rockefeller University) ;
Schneider, W. M. (Rockefeller University) ;
Razooky, B. S. (Rockefeller University) ;
Hoffmann, Hans-Heinrich (Rockefeller University) ;
Michailidis, E. (Rockefeller University) ;
Rice, Charles M. (Rockefeller University) ;
Sabli, Ira K. D. (Imperial College London) ;
Hodeib, Stephanie (Imperial College London) ;
Sancho Shimizu, Vanessa (Imperial College London) ;
Bilguvar, Kaya (Yale School of Medicine) ;
Ye, Junqiang (Columbia University) ;
Bolze, Alexandre (Helix) ;
Zhang, Y. (NIAID Clinical Genomics Program) ;
Notarangelo, Luigi (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ;
Su, H. C. (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ;
Zhang, Y. (NIAID Clinical Genomics Program) ;
Notarangelo, L. D. (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ;
Su, H. C. (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ;
Onodi, Fanny (Université de Paris) ;
Korniotis, Sarantis (Université de Paris) ;
Karpf, Léa (Université de Paris. Institut de Recherche Saint-Louis. INSERM U976. Hôpital Saint-Louis) ;
Soumelis, V. (AP-HP. Hôpital Saint-Louis. Laboratoire d'Immunologie) ;
Bonnet-Madin, Lucie (Université de Paris. Institut de Recherche Saint-Louis) ;
Amara, A. (Université de Paris. Institut de Recherche Saint-Louis) ;
Dorgham, Karim (Sorbonne Université. Inserm. Centre d'Immunologie et des Maladies Infectieuses-Paris (CIMI PARIS). Assistance Publique-Hôpitaux de Paris (AP-HP). Hôpital Pitié-Salpêtrière) ;
Gorochov, Guy (Sorbonne Université) ;
Smith, N. (Institut Pasteur) ;
Duffy, Darragh (Institut Pasteur) ;
Moens, L. (University Hospitals Leuven (Bèlgica)) ;
Meyts, I. (KU Leuven. Department of Immunology. Microbiology and Transplantation) ;
Meade, P. (Department of Microbiology) ;
Garcia-Sastre, Adolfo (Tisch Cancer Institute) ;
Krammer, Florian (Department of Microbiology) ;
Corneau, A. (Sorbonne Université) ;
Masson, C. (Imagine Institute) ;
Schmitt, Y. (Imagine Institute) ;
Schluter, A. (Neurometabolic Diseases Laboratory) ;
Pujol, Aurora 1968- (Institut d'Investigació Biomèdica de Bellvitge) ;
Khan, T. (Sidra Medicine) ;
Marr, Nico (Hamad Bin Khalifa University) ;
Fellay, Jacques (Swiss Federal Institute of Technology Lausanne) ;
Roussel, L. (McGill University Health Centre) ;
Vinh, D. C. (McGill University Health Centre) ;
Shahrooei, M. (Saeed Pathobiology and Genetic Lab) ;
Alosaimi, M. F. (College of Medicine. King Saud University) ;
Alsohime, F. ;
Hasanato, R. (Department of Pathology and Laboratory Medicine. College of Medicine. King Saud University) ;
Mansouri, D. (Shahid Beheshti University of Medical Sciences) ;
Al-Saud, H. (National Center of Genomics Technology. King Abdulaziz City for Science and Technology) ;
Almourfi, F. (National Center of Genomics Technology. King Abdulaziz City for Science and Technology) ;
Al-Mulla, F. (Kuwait University) ;
Al-Muhsen, S. Z. (Immunology Research Laboratory. Department of Pediatrics. College of Medicine. King Saud University Medical City. King Saud University) ;
Al Turki, S. (Cancer & Blood Research. King Abdullah International Medical Research Center) ;
van de Beek, D. (Amsterdam UMC. University Medical Center) ;
Biondi, A. (Pediatric Departement. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale) ;
Bettini, L. R. (Pediatric Departement. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale) ;
D'Angio, M. (Pediatric Departement. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale) ;
Bonfanti, Paolo (Department of Infectious Diseases. San Gerardo Hospital. University of Milano-Bicocca) ;
Imberti, L. (CREA Laboratory. Diagnostic Laboratory. ASST Spedali Civili di Brescia) ;
Sottini, A. (CREA Laboratory. Diagnostic Laboratory. ASST Spedali Civili di Brescia) ;
Paghera, S. (CREA Laboratory. Diagnostic Laboratory. ASST Spedali Civili di Brescia) ;
Quiros-Roldan, E. (Department of Infectious and Tropical Diseases. University of Brescia. ASST Spedali di Brescia) ;
Rossi, C. (Medical Officer. ASST Spedali Civili di Brescia) ;
Oler, A. J. (Bioinformatics and Computational Biosciences Branch. Office of Cyber Infrastructure and Computational Biology. NIAID. NIH) ;
Tompkins, M. F. (PRIMER. Uniformed Services University of the Health Sciences) ;
Alba, Camille (PRIMER. Uniformed Services University of the Health Sciences) ;
Dalgard, C. L. (American Genome Center. Uniformed Services University of the Health Sciences) ;
Vandernoot, Isabelle (Center of Human Genetics. Hôpital Erasme. Université Libre de Bruxelles) ;
Smits, Guillaume (Center of Human Genetics. Hôpital Erasme. Université Libre de Bruxelles) ;
Goffard, Jean-Christope (Department of Internal Medicine. Hôpital Erasme. Université Libre de Bruxelles) ;
Migeotte, Isabelle (Hôpital Erasme) ;
Haerynck, Filomeen (Department of Paediatric Immunology and Pulmonology. Centre for Primary Immunodeficiency Ghent (CPIG). PID Research Lab. Jeffrey Modell Diagnosis and Research Centre. Ghent University Hospital) ;
Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron) ;
Martín-Nalda, Andrea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Colobrán Oriol, Roger (Hospital Universitari Vall d'Hebron) ;
Morange, Pierre-Emmanuel (Aix Marseille Univ) ;
Keles, Sevgi (Meram Medical Faculty. Necmettin Erbakan University. Meram Medical Faculty) ;
Çölkesen, Fatma (Department of Infectious Diseases and Clinical Microbiology. Konya Training and Research Hospital) ;
Ozcelik, Tayfun (Bilkent University) ;
Yasar, Tayfun Kart (Departments of Infectious Diseases and Clinical Microbiology. Bakirkoy Dr. Sadi Konuk Training and Research Hospital. University of Health Sciences) ;
Senoglu, Sevtap (Departments of Infectious Diseases and Clinical Microbiology. Bakirkoy Dr. Sadi Konuk Training and Research Hospital. University of Health Sciences) ;
Karabela, Şemsi Nur (Departments of Infectious Diseases and Clinical Microbiology. Bakirkoy Dr. Sadi Konuk Training and Research Hospital. University of Health Sciences) ;
Rodríguez-Gallego, Carlos (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Novelli, Giuseppe (University of Rome "Tor Vergata) ;
Hraiech, Sami (Intensive Care Unit) ;
Tandjaoui-Lambiotte, Yacine (Avicenne Hospital) ;
Duval, Xavier (Hôpital Bichat Claude Bernard) ;
Laouénan, Cédric (Hôpital Bichat) ;
Duval, X. (Hôpital Bichat Claude Bernard) ;
Snow, Andrew (Uniformed Services University of the Health Sciences, Bethesda) ;
Dalgard, Clifton L. (American Genome Center) ;
Milner, Joshua D. (Columbia University) ;
Mogensen, Trine Hyrup (Aarhus University) ;
Spaan, András N. (Univer-sity Medical Center Utrecht) ;
Bustamante, Jacinta (Necker Hospital for Sick Children) ;
Ciancanelli, Michael J. (Turnstone Biologics) ;
Maniatis, Tom (New York Genome Center) ;
Soumelis, Vassili (Hôpital Saint-Louis, Paris) ;
Nussenzweig, Michel (Howard Hughes Medical Institute) ;
Garcia-Sastre, Adolfo (Icahn School of Medicine) ;
Lifton, Richard P. (Yale School of Medicine) ;
Foti, Giuseppe (University of Milano-Bicocca) ;
Bellani, G. (University of Milano-Bicocca) ;
Citerio, Giuseppe (University of Milano-Bicocca) ;
Contro, E. (University of Milano-Bicocca) ;
Pesci, Alberto (University of Milano-Bicocca.) ;
Valsecchi, M. G. (University of Milano-Bicocca) ;
Cazzaniga, M. (University of Milano-Bicocca) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Blanco Guillermo, Ignacio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rodrigo, C. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Aguilera-Albesa, Sergio (Complejo Hospitalario de Navarra) ;
Akcan, O. M. (Necmettin Erbakan University) ;
Darazam, I. A. (Shahid Beheshti University of Medical Sciences) ;
Aldave, J. C. (Hospital Nacional Edgardo Rebagliati Martins) ;
Ramos, M. A. (Parc Sanitari Sant Joan de Déu) ;
Nadji, S. A. (Shahid Beheshti University of Medical Sciences) ;
Alkan, G. (Selcuk University) ;
Allardet-Servent, J. (Hôpital Européen) ;
Allende-Martinez, Luis M (Hospital Universitario 12 de Octubre (Madrid)) ;
Alsina, L. (Hospital Sant Joan de Déu (Manresa)) ;
Alyanakian, M. A. (Necker Hospital for Sick Children) ;
Amador-Borrero, B. (Université de Paris) ;
Mouly, S. (Internal Medicine Department. Hôpital Lariboisière. APHP. Université de Paris) ;
Sene, D. (Internal Medicine Department. Hôpital Lariboisière. APHP. Université de Paris) ;
Amoura, Zahir (Internal Medicine Department. Pitié-Salpétrière Hospital) ;
Mathian, Alexis (Internal Medicine Department. Pitié-Salpétrière Hospital) ;
Antolí, Arnau (Hospital Universitari de Bellvitge) ;
Blanch, G. R. (Hospital Universitari de Bellvitge) ;
Riera, J. S. (Hospital Universitari de Bellvitge) ;
Moreno, X. S. (Hospital Universitari de Bellvitge) ;
Arslan, S. (Necmettin Erbakan University) ;
Assant, S. (Lyon Sud Hospital) ;
Auguet, Teresa (Hospital Universitari Joan XXIII de Tarragona) ;
Azot, A. (Private Practice) ;
Bajolle, F. (Necker Hospital for Sick Children) ;
Bustamante, J. (Necker Hospital for Sick Children) ;
Lévy, R. (Necker Hospital for Sick Children) ;
Oualha, M. (Necker Hospital for Sick Children) ;
Baldolli, A. (Department of Infectious Diseases) ;
Ballester Devis, Maria (Consorcio Hospital General Universitario) ;
Feldman, H. B. (Tel Aviv University) ;
Barrou, B. (Sorbonne Université.) ;
Beurton, Alexandra (Hôpital Pitié-Salpêtrière) ;
Bilbao, A. (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Blanchard-Rohner, G. (Geneva University Hospitals (Suïssa)) ;
Blandinières, A. (Georges Pompidou Hospital) ;
Rivet, N. (Georges Pompidou Hospital) ;
Blázquez-Gamero, Daniel (Hospital Universitario 12 de Octubre (Madrid)) ;
Bloomfield, M. (Motol University Hospital) ;
Bolivar-Prados, Mireia (Hospital de Mataró. Consorci Sanitari del Maresme) ;
Clavé i Civit, Pere (rie, R.) ;
Bosteels, C. (Universitair Ziekenhuis Gent) ;
Lambrecht, B. N. (Universitair Ziekenhuis Gent) ;
van Braeckel, E. (Universitair Ziekenhuis Gent) ;
Bousfiha, Ahmed A (Averroes University Hospital D'Inflammation et d'Allergie. Hassann II University) ;
Bouvattier, C. (Endocrinology Unit. APHP Hôpitaux Universitaires Paris-Sud) ;
Vincent, A. (Endocrinology Unit. APHP Hôpitaux Universitaires Paris-Sud) ;
Boyarchuk, O. (I. Horbachevsky Ternopil National Medical University) ;
Bueno, M. R. P. (University of São Paulo) ;
Castro, M. V. (University of São Paulo) ;
Matos, L. R. B. (University of São Paulo) ;
Zatz, M. (Human Genome and Stem-Cell Research Center. University of São Paulo) ;
Agra, J. J. C. (Hospital Universitario Insular de Gran Canaria) ;
Calimli, S. (Konya State Hospital) ;
Capra, R. (Spedali Civili) ;
Carrabba, M. (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
Fabio, G. (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
Casasnovas, Carlos (Hospital Universitari de Bellvitge) ;
Vélez-Santamaria, V. (Hospital Universitari de Bellvitge) ;
Caseris, M. (Hopital Robert Debré) ;
Falck, A. (Hopital Robert Debré) ;
Poncelet, G. (Hopital Robert Debré) ;
Castelle, M. (Necker Enfants Malades Hospital) ;
Castelli, F. (University of Brescia) ;
de Vera, M. C. (Canarian Health System) ;
Catherinot, E. (Hôpital Foch) ;
Chalumeau, M. (Necker Hospital for Sick Children) ;
Toubiana, J. (Necker Hospital for Sick Children) ;
Charbit, B. (Pasteur Institute) ;
Li, Z. (Pasteur Institute) ;
Pellegrini, S. (Pasteur Institute) ;
Cheng, M. P. (McGill University Health Centre) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Codina, A. (Institut de Recerca Sant Joan de Déu) ;
Çölkesen, F. (Necmettin Erbakan University) ;
Çölkesen, F. (Konya Training and Research Hospital) ;
Colobrán Oriol, Roger (Hospital Universitari Vall d'Hebron) ;
Comarmond, C. (Pitié-Salpêtrière Hospital) ;
Dalmau, David (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Darley, D. R. (Vincent's Hospital Darlinghurst) ;
Dauby, N. (Université Libre de Bruxelles) ;
Dauger, S. (Robert-Debré University Hospital) ;
Le Bourgeois, F. (Robert-Debré University Hospital) ;
Levy, M. (Robert-Debré University Hospital) ;
de Pontual, L. (Hôpital Jean Verdier) ;
Dehban, A. (Sina Medical Complex) ;
Delplancq, G. (Centre de Génétique Humaine) ;
Demoule, A. (Sorbonne Université Médecine) ;
Diehl, J. L. (Georges Pompidou Hospital) ;
Dobbelaere, S. (AZ Delta) ;
Durand, Sophie (Institut Jérôme Lejeune) ;
Mircher, C. (Institut Jérôme Lejeune) ;
Rebillat, A. S. (Institut Jérôme Lejeune) ;
Vilaire, M. E. (Institut Jérôme Lejeune) ;
Eldars, W. (DMansoura University) ;
Elgamal, M. (Mansoura University) ;
Elnagdy, M. H. (Mansoura University) ;
Emiroglu, M. (Selcuk University) ;
Erdeniz, E. H. (Ondokuz Mayıs University) ;
Aytekin, S. E. (Necmettin Erbakan University) ;
Euvrard, R. (Centre Hospitalier Fleyriat) ;
Evcen, R. (Necmettin Erbakan University) ;
Faivre, L. (CHU Dijon) ;
Fartoukh, M. (APHP Tenon Hospital) ;
Philippot, Q. (APHP Tenon Hospital) ;
Faure, M. (Sorbonne Universités) ;
Arquero, M. F. (Hospital Clínico San Carlos (Madrid)) ;
Flores, Carlos (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Francois, B. (CHU Limoges) ;
Fumadó, Victoria (Universitat de Barcelona) ;
Fusco, Francesca (Institute of Genetics and Biophysics "Adriano Buzzati-Traverso) ;
Ursini, M. V. (Institute of Genetics and Biophysics "Adriano Buzzati-Traverso) ;
Solis, B. G. (Hospital Universitario La Paz (Madrid)) ;
de Diego, R. P. (Hospital Universitario La Paz (Madrid)) ;
van Den Rym, A. M. (Hospital Universitario La Paz (Madrid)) ;
Gaussem, P. (Department of Hematology. APHP. Hopital Européen Georges Pompidou. Inserm UMR-S1140) ;
Gil-Herrera, J. (Hos-pital General Universitario. Instituto de Investigación Sanitaria "Gregorio Marañón) ;
Gilardin, L. (Bégin Military Hospital) ;
Girona-Alarcón, Mònica (Hospital Sant Joan de Déu (Manresa)) ;
Goffard, J. C. (Université Libre de Bruxelles) ;
Gok, F. (Necmettin Erbakan University) ;
Yosunkaya, A. (Necmettin Erbakan University) ;
Thy, M. (Center for Clinical Investigation. Assistance Publique-Hôpitaux de Paris. Bichat-Claude Bernard University Hospital) ;
van Agtmael, Michiel (Department of Infectious Diseases. Amsterdam UMC) ;
Bomers, Marije (Department of Infectious Diseases. Amsterdam UMC) ;
Chouchane, Osoul (Department of Infectious Diseases. Amsterdam UMC) ;
Geerlings, Suzanne (Department of Infectious Diseases. Amsterdam UMC) ;
Goorhuis, Bram (Department of Infectious Diseases. Amsterdam UMC) ;
Grobusch, Martin P. (Department of Infectious Diseases. Amsterdam UMC) ;
Harris, Vanessa (Department of Infectious Diseases. Amsterdam UMC) ;
Hermans, Sabine M. (Department of Infectious Diseases. Amsterdam UMC) ;
Hovius, Joppe W. (Department of Infectious Diseases. Amsterdam UMC) ;
Nellen, Jeaninne (Department of Infectious Diseases. Amsterdam UMC) ;
Peters, Edgar (Department of Infectious Diseases. Amsterdam UMC) ;
van der Poll, Tom (Department of Infectious Diseases. Amsterdam UMC) ;
Prins, Jan M. (Department of Infectious Diseases. Amsterdam UMC) ;
Reijnders, Tom (Department of Infectious Diseases. Amsterdam UMC) ;
Schinkel, Michiel (Department of Infectious Diseases. Amsterdam UMC) ;
Sigaloff, Kim (Department of Infectious Diseases. Amsterdam UMC) ;
Stijnis, Cornelis S. (Department of Infectious Diseases. Amsterdam UMC) ;
van der Valk, Marc (Department of Infectious Diseases. Amsterdam UMC) ;
van Vugt, Michèle (Department of Infectious Diseases. Amsterdam UMC) ;
Joost Wiersinga, W. (Department of Infectious Diseases. Amsterdam UMC) ;
Algera, Anna Geke (Department of Intensive Care. Amsterdam UMC) ;
van Baarle, Frank (Department of Intensive Care. Amsterdam UMC) ;
Bos, Lieuwe D.. (Department of Intensive Care. Amsterdam UMC) ;
Botta, Michela (Department of Intensive Care. Amsterdam UMC) ;
de Bruin, Sanne (Department of Intensive Care. Amsterdam UMC) ;
Bulle, Esther (Department of Intensive Care. Amsterdam UMC) ;
Elbers, Paul (Department of Intensive Care. Amsterdam UMC) ;
Fleuren, Lucas (Department of Intensive Care. Amsterdam UMC) ;
Girbes, Armand (Department of Intensive Care. Amsterdam UMC) ;
Hagens, Laura (Department of Intensive Care. Amsterdam UMC) ;
Heunks, Leo (Department of Intensive Care. Amsterdam UMC) ;
Horn, Janneke (Department of Intensive Care. Amsterdam UMC) ;
van Mourik, Niels (Department of Intensive Care. Amsterdam UMC) ;
Paulus, Frederique (Department of Intensive Care. Amsterdam UMC) ;
Raasveld, Jorinde (Department of Intensive Care. Amsterdam UMC) ;
Schultz, Marcus J. (Department of Intensive Care. Amsterdam UMC) ;
Smit, Marry (Department of Intensive Care. Amsterdam UMC) ;
Stilma, Willemke (Department of Intensive Care. Amsterdam UMC) ;
Thoral, Patrick (Department of Intensive Care. Amsterdam UMC) ;
Tsonas, Anissa M (Department of Intensive Care. Amsterdam UMC) ;
de Vries, Heder (Department of Intensive Care. Amsterdam UMC) ;
Bax, Diane (Experimental Immunology. Amsterdam UMC) ;
Cloherty, Alex (Experimental Immunology. Amsterdam UMC) ;
Beudel, Martijn (Department of Neurology. Amsterdam UMC. Amsterdam Neuroscience) ;
Brouwer, Matthijs C. (Department of Neurology. Amsterdam UMC. Amsterdam Neuroscience) ;
Koning, Rutger (Department of Neurology. Amsterdam UMC. Amsterdam Neuroscience) ;
van de Beek, Diederik (Amsterdam UMC. University Medical Center) ;
Bogaard, H. J. (Department of Pulmonology. Amsterdam UMC) ;
de Brabander, J. (Department of Infectious Diseases. Amsterdam UMC) ;
de Bree, G. (Department of Infectious Diseases. Amsterdam UMC) ;
Bugiani, Marianna (Department of Pathology. Amsterdam UMC) ;
Geerts, Bart (Department of Anesthesiology. Amsterdam UMC) ;
Hollmann, Markus W. (Department of Anesthesiology. Amsterdam UMC) ;
Preckel, Benedikt (Department of Anesthesiology. Amsterdam UMC) ;
Veelo, Denise (Department of Anesthesiology. Amsterdam UMC) ;
Geijtenbeek, Theo (Department of Experimental Immunology. Amsterdam UMC) ;
Hafkamp, Florianne (Department of Experimental Immunology. Amsterdam UMC) ;
Hamann, Jorg (Amsterdam UMC Biobank Core Facility. Amsterdam UMC) ;
Hemke, Robert (Department of Radiology. Amsterdam UMC) ;
de Jong, Menno D. (Department of Medical Microbiology. Amsterdam UMC) ;
Schuurman, Alex (Department of Internal Medicine. Amsterdam UMC) ;
Teunissen, Charlotte (Neurochemical Laboratory. Amsterdam UMC) ;
Vlaar, Alexander P. J. (Department of Intensive Care. Amsterdam UMC) ;
Wouters, Dorien (Department of Clinical Chemistry. Amsterdam UMC) ;
Zwinderman, A. H. (Department of Clinical Epidemiology. Biostatistics and Bioinformatics. Amsterdam UMC) ;
Abel, Laurent (INSERM U1163. University of Paris. Imagine Institute) ;
Aiuti, Alessandro (San Raffaele Telethon Institute for Gene Therapy. IRCCS Ospedale San Raffaele) ;
Muhsen, Saleh Al (King Saud University) ;
Al-Mulla, Fahd (Kuwait University) ;
Anderson, Mark S. (University of California. San Francisco) ;
Feldman, Hagit Baris (Genetics Institute. Tel Aviv Sourasky Medical Center. Sackler Faculty of Medicine. Tel Aviv University) ;
Bogunovic, Dusan (Icahn School of Medicine) ;
Itan, Yuval (Icahn School of Medicine) ;
Bolze, Alexandre (Helix) ;
Cirulli, Elizabeth (Helix) ;
Barrett, Kelly Schiabor . (Helix) ;
Washington, Nicole (Helix) ;
Bondarenko, Anastasiia (Shupyk National Medical Academy for Postgraduate Education) ;
Bousfiha, Ahmed A. (Clinical Immunology Unit. Pediatric Infectious Disease Departement. Faculty of Medicine and Pharmacy. Averroes University Hospital. LICIA Laboratoire d'Immunologie Clinique. D'Inflammation et d'Allergie. Hassann II University) ;
Brodin, Petter (Karolinska Institutet (Estocolm, Suècia)) ;
Bryceson, Yenan (Karolinska Institutet (Estocolm, Suècia)) ;
Bustamante, Carlos D. (Stanford University) ;
Butte, Manish J (University of California) ;
Casari, Giorgio (Medical Genetics. IRCCS Ospedale San Raffaele) ;
Chakravorty, Samya (Emory University. Department of Pediatrics. Children's Healthcare of Atlanta) ;
Christodoulou, John (Murdoch Children's Research Institute) ;
Le Mestre, S. (University of São Paulo) ;
Condino-Neto, Antonio (University of São Paulo) ;
Cooper, Megan A. (Washington University School of Medicine) ;
Dalgard, Clifton L. (American Genome Center. Uniformed Services University of the Health Sciences) ;
David, Alessia (Centre for Bioinformatics and System Biology. Department of Life Sciences. Imperial College London. South Kensington Campus) ;
DeRisi, Joseph L. (Chan Zuckerberg Biohub) ;
Desai, Murkesh (Bai Jerbai Wadia Hospital for Children) ;
Drolet, Beth A. (School of Medicine and Public Health. University of Wisconsin) ;
Espinosa, Sara (Instituto Nacional de Pediatria. (National Institute of Pediatrics)) ;
Fellay, Jacques (Swiss Federal Institute of Technology Lausanne) ;
Flores, Carlos (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Franco, Jose Luis (University of Antioquia) ;
Gregersen, Peter K. (Feinstein Institute for Medical Research. Northwell Health USA) ;
Haerynck, Filomeen (Department of Paediatric Immunology and Pulmonology. Centre for Primary Immunodeficiency Ghent (CPIG). PID Research Lab. Jeffrey Modell Diagnosis and Research Centre. Ghent University Hospital) ;
Hagin, David (Genetics Institute. Tel Aviv Sourasky Medical Center) ;
Halwani, Rabih (Sharjah Institute of Medical Research. College of Medicine. University of Sharjah) ;
Heath, Jim (Institute for Systems Biology) ;
Henrickson, Sarah E. (Children's Hospital of Philadelphia (Pennsilvània)) ;
Hsieh, Elena (Anschutz Medical Campus) ;
Imai, Kohsuke (Riken) ;
Karamitros, Timokratis (Hellenic Pasteur Institute) ;
Kisand, Kai (University of Tartu) ;
Ku, Cheng-Lung. (Chang Gung University) ;
Lau, Yu-Lung (University of Hong Kong) ;
Ling, Yun (Shanghai Public Health Clinical Center. Fudan University) ;
Lucas, Carrie L. (Yale School of Medicine) ;
Mansouri, Davoud (Shahid Beheshti University of Medical Sciences) ;
Marodi, Laszlo (Semmelweis University Budapest) ;
Milner, Joshua (Columbia University Medical Center) ;
Mironska, Kristina (University Clinic for Children's Diseases) ;
Morio, Tomohiro (Tokyo Medical & Dental University Hospital) ;
Notarangelo, Luigi (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ;
Su, Helen C. (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ;
Novelli, Antonio (Bambino Gesù Children's Hospital) ;
Novelli, Giuseppe (Department of Biomedicine and Prevention. University of Rome "Tor Vergata) ;
O'Farrelly, Cliona (Trinity College) ;
Okada, Satoshi (Hiroshima University) ;
Ozcelik, Tayfun (Bilkent University) ;
Perez de Diego, Rebeca (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ;
Planas, Anna M. (IIBB-CSIC. IDIBAPS) ;
Prando, Carolina (Faculdades Pequeno Príncipe. Instituto de Pesquisa Pelé Pequeno Príncipe) ;
Pujol, Aurora 1968- (Institut d'Investigació Biomèdica de Bellvitge) ;
Quintana-Murci, Luis (Institut Pasteur. CNRS. UMR 2000. Collège de France) ;
Renia, Laurent (Infectious Diseases Horizontal Technology Center. Singapore Immunology Network. Agency for Science Technology (A*STAR)) ;
Renieri, Alessandra (Medical Genetics. University of Siena) ;
Rodríguez-Gallego, Carlos (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Sancho Shimizu, Vanessa (Imperial College London) ;
Sankaran, Vijay (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ;
Shahrooei, Mohammed (Saeed Pathobiology and Genetic Lab) ;
Snow, Andrew (Uniformed Services University of the Health Sciences) ;
Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron) ;
Tangye, Stuart (Garvan Institute of Medical Research (Darlinghurst, Austràlia)) ;
Turvey, Stuart (University of British Columbia) ;
Uddin, Furkan (Holy Family Red Crescent Medical College. Centre for Precision Therapeutics. NeuroGen Children's Healthcare. Genetics and Genomic Medicine Centre. NeuroGen Children's Healthcare) ;
Uddin, Mohammed J. (Centre for Applied Genomics. Department of Genetics and Genome Biology. Hospital for Sick Children) ;
van de Beek, Diederik (Amsterdam UMC. University Medical Center) ;
Vazquez, Sara E. (University of California) ;
Vinh, Donald C. (McGill University Health Centre) ;
von Bernuth, Horst (Charité-Berlin University Hospital Center) ;
Zawadzki, Pawel (Molecular Biophysics Division. Faculty of Physics. A. Mickiewicz University) ;
Jing, H. (NIAID Clinical Genomics Program. National Institutes of Health) ;
Tung, W. (NIAID Clinical Genomics Program. National Institutes of Health) ;
Meguro, K. (NIAID Clinical Genomics Program. National Institutes of Health) ;
Shaw, E. (NIAID Clinical Genomics Program. National Institutes of Health) ;
Jing, Huie (NIAID Clinical Genomics Program. National Institutes of Health) ;
Tung, Wesley (NIAID Clinical Genomics Program. National Institutes of Health) ;
Shafer, S. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Zheng, L. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Zhang, Z. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Kubo, S. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Chauvin, S. D. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Meguro, K. (NIAID Clinical Genomics Program. National Institutes of Health) ;
Shaw, Elana (NIAID Clinical Genomics Program. National Institutes of Health) ;
Lenardo, M. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Luthers, Christopher R. (Department of Pharmacology & Molecular Therapeutics. Uniformed Services University of the Health Sciences) ;
Bauman, Bradly M. (Department of Pharmacology & Molecular Therapeutics. Uniformed Services University of the Health Sciences) ;
Shafer, Samantha (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Zheng, Lixin (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Zhang, Zinan (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Kubo, Satoshi (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Chauvin, Samuel D. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Lenardo, Michael (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ;
Lack, Justin (NIAID Collaborative Bioinformatics Resource. Frederick National Laboratory for Cancer Research. Leidos Biomedical Research. Inc.) ;
Karlins, Eric (Bioinformatics and Computational Biosciences Branch. Office of Cyber Infrastructure and Computational Biology. NIAID. NIH) ;
Hupalo, Daniel M. (American Genome Center. Uniformed Services University of the Health Sciences) ;
Rosenberger, John (American Genome Center. Uniformed Services University of the Health Sciences) ;
Sukumar, Gauthaman (American Genome Center. Uniformed Services University of the Health Sciences) ;
Wilkerson, Matthew D. (American Genome Center. Uniformed Services University of the Health Sciences) ;
Zhang, Xijun (American Genome Center. Uniformed Services University of the Health Sciences) ;
Universitat Autònoma de Barcelona
Clinical outcome upon infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranges from silent infection to lethal coronavirus disease 2019 (COVID-19). We have found an enrichment in rare variants predicted to be loss-of-function (LOF) at the 13 human loci known to govern Toll-like receptor 3 (TLR3)- and interferon regulatory factor 7 (IRF7)-dependent type I interferon (IFN) immunity to influenza virus in 659 patients with life-threatening COVID-19 pneumonia relative to 534 subjects with asymptomatic or benign infection. [...]
2020 -  10.1126/science.abd4570
Science, Vol. 370 Núm. 6515 (23 2020) , p. eabd4570
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Autoantibodies against type I IFNs in patients with life-threatening COVID-19
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Bastard, Paul (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Rosen, Lindsey B. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Zhang, Qian (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Michailidis, Eleftherios (The Rockefeller University. Laboratory of Virology and Infectious Disease) ;
Hoffmann, Hans-Heinrich (The Rockefeller University. Laboratory of Virology and Infectious Disease) ;
Zhang, Yu (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Dorgham, Karim (Sorbonne Université. Centre d'Immunologie et des Maladies Infectieuses) ;
Philippot, Quentin (University of Paris. Imagine Institute) ;
Rosain, Jérémie (University of Paris. Imagine Institute) ;
Béziat, Vivien (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Manry, Jeremy (University of Paris. Imagine Institute) ;
Shaw, Elana (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Haljasmägi, Liis (University of Tartu. Institute of Biomedicine and Translational Medicine) ;
Peterson, Pärt (University of Tartu. Institute of Biomedicine and Translational Medicine) ;
Lorenzo, Lazaro (University of Paris. Imagine Institute) ;
Bizien, Lucy (University of Paris. Imagine Institute) ;
Trouillet-Assant, Sophie (Lyon University. International Center of Research in Infectiology) ;
Dobbs, Kerry (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Almeida de Jesus, Adriana (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Belot, Alexandre (Lyon Immunopathology Federation. Hospices Civils de Lyon) ;
Kallaste, Anne (Internal Medicine Clinic. Tartu University Hospital) ;
Catherinot, Emilie (Hôpital Foch) ;
Tandjaoui-Lambiotte, Yacine (Avicenne Hospital. Assistance Publique Hôpitaux de Paris) ;
Le Pen, Jérémie (The Rockefeller University. Laboratory of Virology and Infectious Disease) ;
Kerner, Gaspard (University of Paris. Imagine Institute) ;
Bigio, Benedetta (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Seeleuthner, Yoann (University of Paris. Imagine Institute) ;
Yang, Rui (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Bolze, Alexandre (Helix) ;
Spaan, András N. (University Medical Center Utrecht) ;
Delmonte, Ottavia M. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Abers, Michael S. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Aiuti, Alessandro (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Casari, Giorgio (Medical Genetics. IRCCS Ospedale San Raffaele) ;
Lampasona, Vito (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Piemonti, Lorenzo (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Ciceri, Fabio (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Bilguvar, Kaya (Yale University School of Medicine. Department of Genetics) ;
Lifton, Richard P. (Rockefeller University. Laboratory of Human Genetics and Genomics) ;
Vasse, Marc (Consorcio Hospital. General Universitario) ;
Smadja, David M. (Paris University. European Georges Pompidou Hospital) ;
Migaud, Mélanie (University of Paris. Imagine Institute) ;
Hadjadj, Jérome (Hôpital Cochin. Department of Internal Medicine) ;
Terrier, Benjamin (Université de Paris. Department of Internal Medicine) ;
Duffy, Darragh (Pasteur Institute) ;
Quintana-Murci, Lluis (Institut Pasteur. Collège de France) ;
van de Beek, Diederik (Amsterdam UMC. University Medical Center) ;
Roussel, Lucie (McGill University Health Centre) ;
Vinh, Donald C. (McGill University Health Centre) ;
Tangye, Stuart (Garvan Institute of Medical Research (Darlinghurst, Austràlia)) ;
Haerynck, Filomeen (Ghent University Hospital. (Bèlgica)) ;
Dalmau, David (Fundació Docència i Recerca Mútua Terrassa) ;
Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Brodin, Petter (Karolinska Institutet (Estocolm, Suècia)) ;
Nussenzweig, Michel (Howard Hughes Medical Institute) ;
Boisson-Dupuis, Stephanie (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Rodríguez-Gallego, Carlos (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Vogt, Guillaume (University of Paris. Neglected Human Genetics Laboratory) ;
Mogensen, Trine Hyrup (Aarhus University) ;
Oler, Andrew J. (Bioinformatics and Computational Biosciences Branch. Office of Cyber Infrastructure and Computational Biology. NIAID. NIH) ;
Gu, Jingwen (Bioinformatics and Computational Biosciences Branch. Office of Cyber Infrastructure and Computational Biology. NIAID. NIH) ;
Burbelo, Peter D. (Division of Intramural Research. National Institute of Dental Craniofacial Research (NIDCR). NIH) ;
Cohen, Jeffrey I. (Laboratory of Infectious Diseases. Division of Intramural Research. NIAID. NIH) ;
Biondi, Andrea (Pediatric Department. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBMOspedale) ;
Bettini, Laura Rachele (Pediatric Department. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBMOspedale) ;
D'Angio, Mariella (University of Milano-Bicocca. Pediatric Department) ;
Bonfanti, Paolo (University of Milano-Bicocca. Department of Infectious Diseases) ;
Rossignol, Patrick (University of Lorraine. Plurithematic Clinical Investigation Centre) ;
Mayaux, Julien (APHP Pitié-Salpêtrière Hospital) ;
Rieux-Laucat, Frédéric (Laboratory of Immunogenetics of Pediatric Autoimmune Diseases. INSERM. UMR 1163. University of Paris. Imagine Institute) ;
Husebye, Eystein (Karolinska Institutet (Estocolm, Suècia). Department of Medicine) ;
Fusco, Francesca (Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'. IGB-CNR) ;
Ursini, Matilde Valeria (Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'. IGB-CNR) ;
Imberti, Luisa (Centro di Ricerca Emato-oncologica AIL (CREA) Laboratory. Diagnostic Department. ASST Spedali Civili di Brescia) ;
Sottini, Alessandra (Centro di Ricerca Emato-oncologica AIL (CREA) Laboratory. Diagnostic Department. ASST Spedali Civili di Brescia) ;
Paghera, Simone (Centro di Ricerca Emato-oncologica AIL (CREA) Laboratory. Diagnostic Department. ASST Spedali Civili di Brescia) ;
Quiros-Roldan, Eugenia (Department of Infectious and Tropical Diseases. University of Brescia. ASST Spedali di Brescia) ;
Rossi, Camillo (Direzione Sanitaria. ASST Spedali Civili di Brescia) ;
Castagnoli, Riccardo (Department of Pediatrics. Fondazione IRCCS Policlinico San Matteo. University of Pavia) ;
Montagna, Daniela (Department of Clinical. Surgical. Diagnostic and Pediatric Sciences. University of Pavia) ;
Licari, Amelia (Department of Pediatrics. Fondazione IRCCS Policlinico San Matteo. University of Pavia) ;
Marseglia, Gian Luigi (Department of Pediatrics. Fondazione IRCCS Policlinico San Matteo. University of Pavia) ;
Duval, Xavier (Centre d'Investigation Clinique. Inserm CIC 1425. Hôpital Bichat Claude Bernard. APHP) ;
Ghosn, Jade (Hôpital Bichat) ;
Tsang, John S. (Multiscale Systems Biology Section. Laboratory of Immune System Biology. NIAID. NIH) ;
Goldbach-Mansky, Raphaela (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Kisand, Kai (Institute of Biomedicine and Translational Medicine. University of Tartu) ;
Lionakis, Michail S. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Puel, Anne (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ;
Zhang, Shein-Ying (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ;
Holland, Steven M. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Gorochov, Guy (Département d'Immunologie. AP-HP. Hôpital Pitié-Salpétrière) ;
Jouanguy, Emmanuelle (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ;
Rice, Charles M. (Laboratory of Virology and Infectious Disease. The Rockefeller University) ;
Cobat, Aurélie (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ;
Notarangelo, Luigi (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Abel, Laurent (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ;
Su, Helen C. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Casanova, Jean-Laurent (Pediatric Hematology and Immunology Unit. Necker Hospital for Sick Children. AP-HP) ;
The University of Hong Kong
HGID Lab ;
The University of Hong Kong
NIAID-USUHS Immune Response to COVID Group ;
COVID Clinicians ;
COVID-STORM Clinicians ;
Imagine COVID Group ;
French COVID Cohort Study Group ;
The Milieu Intérieur Consortium ;
CoV-Contact Cohort ;
Amsterdam UMC Covid-19 Biobank ;
COVID Human Genetic Effort ;
Universitat Autònoma de Barcelona
Interindividual clinical variability in the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is vast. We report that at least 101 of 987 patients with life-threatening coronavirus disease 2019 (COVID-19) pneumonia had neutralizing immunoglobulin G (IgG) autoantibodies (auto-Abs) against interferon-w (IFN-w) (13 patients), against the 13 types of IFN-a (36), or against both (52) at the onset of critical disease; a few also had auto-Abs against the other three type I IFNs. [...]
2020 - 10.1126/science.abd4585
Science, Vol. 370 Núm. 6515 (september 2020) , p. eabd4585
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