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Artículos, Encontrados 2 registros
Artículos Encontrados 2 registros  
1.
36 p, 1.9 MB Time course study of long-term biocompatibility and foreign body reaction to intraneural polyimide-based implants / de la Oliva, Natalia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Navarro, X. (Xavier) (Xavier) (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Del Valle, Jaume (Institut Català de Nanociència i Nanotecnologia)
The foreign body reaction (FBR) against an implanted device is characterized by the formation of a fibrotic tissue around the implant. In the case of interfaces for peripheral nerves, used to stimulate specific group of axons and to record different nerve signals, the FBR induces a matrix deposition around the implant creating a physical separation between nerve fibers and the interface that may reduce its functionality over time. [...]
2018 - 10.1002/jbm.a.36274
Journal of biomedical materials research : Part A, Vol. 106, Issue 3 (March 2018) , p. 746-757  
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2.
26 p, 1.4 MB Dexamethasone Reduces the Foreign Body Reaction to Intraneural Electrode Implants in the Peripheral Nerve of the Rat / de la Oliva, Natalia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Navarro, X. (Xavier) (Xavier) (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Del Valle, Jaume (Institut Català de Nanociència i Nanotecnologia)
Intraneural electrodes must be in intimate contact with nerve fibers to have a proper function, but this interface is compromised due to the foreign body reaction (FBR). The FBR is characterized by a first inflammatory phase followed by a second anti-inflammatory and fibrotic phase, which results in the formation of a tissue capsule around the implant, causing physical separation between the active sites of the electrode and the nerve fibers. [...]
2018 - 10.1002/ar.23920
The anatomical record (Hoboken), Vol. 301, Issue 10 (October 2018) , p. 1722-1733  
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