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Resultats globals: 11 registres trobats en 0.04 segons.
Articles, 11 registres trobats
Articles 11 registres trobats  1 - 10següent  anar al registre:
1.
12 p, 1.1 MB Decoding the role of coiled-coil motifs in human prion-like proteins / Behbahanipour, Molood (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Garcia-Pardo, Javier (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Prions are self-propagating proteins that cause fatal neurodegenerative diseases in humans. However, increasing evidence suggests that eukaryotic cells exploit prion conformational conversion for functional purposes. [...]
2021 - 10.1080/19336896.2021.1961569
Prion, Vol. 15, Issue 1 (August 2021) , p. 143-154  
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2.
8 p, 1.2 MB SGnn : A Web Server for the Prediction of Prion-Like Domains Recruitment to Stress Granules Upon Heat Stress / Iglesias, Valentin (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Santos, Jaime (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Santos-Suárez, Juan (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pintado-Grima, Carlos (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Proteins bearing prion-like domains (PrLDs) are essential players in stress granules (SG) assembly. Analysis of data on heat stress-induced recruitment of yeast PrLDs to SG suggests that this propensity might be connected with three defined protein biophysical features: aggregation propensity, net charge, and the presence of free cysteines. [...]
2021 - 10.3389/fmolb.2021.718301
Frontiers in Molecular Biosciences, Vol. 8 (August 2021) , art. 718301  
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3.
12 p, 3.8 MB Modular Evolution and Population Variability of Oikopleura dioica Metallothioneins / Calatayud, Sara (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; García-Risco, Mario (Universitat Autònoma de Barcelona. Departament de Química) ; Capdevila Vidal, Mercè (Universitat Autònoma de Barcelona. Departament de Química) ; Cañestro, Cristian (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Palacios Bonilla, Òscar (Universitat Autònoma de Barcelona. Departament de Química) ; Albalat, Ricard (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística)
Chordate Oikopleura dioica probably is the fastest evolving metazoan reported so far, and thereby, a suitable system in which to explore the limits of evolutionary processes. For this reason, and in order to gain new insights on the evolution of protein modularity, we have investigated the organization, function and evolution of multi-modular metallothionein (MT) proteins in O. [...]
2021 - 10.3389/fcell.2021.702688
Frontiers in Cell and Developmental Biology, Vol. 9 (July 2021) , art. 702688  
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4.
15 p, 1.8 MB Two Unconventional Metallothioneins in the Apple Snail Pomacea bridgesii Have Lost Their Metal Specificity during Adaptation to Freshwater Habitats / García-Risco, Mario (Universitat Autònoma de Barcelona. Departament de Química) ; Calatayud, Sara (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Niederwanger, Michael (University of Innsbruck. Institute of Zoology) ; Albalat, Ricard (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Palacios Bonilla, Òscar (Universitat Autònoma de Barcelona. Departament de Química) ; Capdevila Vidal, Mercè (Universitat Autònoma de Barcelona. Departament de Química) ; Dallinger, Reinhard (University of Innsbruck. Institute of Zoology)
Metallothioneins (MTs) are a diverse group of proteins responsible for the control of metal homeostasis and detoxification. To investigate the impact that environmental conditions might have had on the metal-binding abilities of these proteins, we have characterized the MTs from the apple snail Pomacea bridgesii, a gastropod species belonging to the class of Caenogastropoda with an amphibious lifestyle facing diverse situations of metal bioavailability. [...]
2021 - 10.3390/ijms22010095
International journal of molecular sciences, Vol. 22, Issue 1 (January 2021) , art. 95  
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5.
16 p, 9.5 MB Characterization of Soft Amyloid Cores in Human Prion-Like Proteins / Batlle Carreras, Cristina (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Sánchez de Groot, Natalia (Centre de Regulació Genòmica) ; Iglesias, Valentin (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Navarro, Susanna (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Prion-like behaviour is attracting much attention due to the growing evidences that amyloid-like self-assembly may reach beyond neurodegeneration and be a conserved functional mechanism. The best characterized functional prions correspond to a subset of yeast proteins involved in translation or transcription. [...]
2017 - 10.1038/s41598-017-09714-z
Scientific reports, Vol. 7 (2017) , art. 12134  
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6.
16 p, 3.9 MB Plasticity in the Oxidative Folding Pathway of the High Affinity Nerita Versicolor Carboxypeptidase Inhibitor (NvCI) / Esperante, Sebastián (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Bronsoms, Sílvia (Universitat Autònoma de Barcelona. Servei de Proteòmica i Biologia Estructural) ; Covaleda Cortés, Giovanni (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Trejo, Sebastián A. (Universitat Autònoma de Barcelona. Servei de Proteòmica i Biologia Estructural) ; Avilés, Francesc X. (Francesc Xavier) (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Nerita Versicolor carboxypeptidase inhibitor (NvCI) is the strongest inhibitor reported so far for the M14A subfamily of carboxypeptidases. It comprises 53 residues and a protein fold composed of a two-stranded antiparallel β sheet connected by three loops and stabilized by three disulfide bridges. [...]
2017 - 10.1038/s41598-017-05657-7
Scientific reports, Vol. 7 (2017) , art. 5457  
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7.
15 p, 3.9 MB Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregationres / Sant'Anna, Ricardo (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Almedia, Maria Rosario (Instituto de Investigação e Inovação em Saúde da Universidade do Porto) ; Varejao, Nathalia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gallego Alonso, Pablo (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Esperante, Sebastián (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ferreira, Priscilla (Instituto de Bioquímica Médica Leopoldo de Meis) ; Pereira-Henriques, Alda (Instituto de Investigação e Inovação em Saúde da Universidade do Porto) ; Palhano, Fernando L. (Instituto de Bioquímica Médica Leopoldo de Meis) ; De Carvalho, Mamede (Department Neurosciences. Hospital de Santa Maria. CHLN) ; Foguel, Debora (Instituto de Bioquímica Médica Leopoldo de Meis) ; Reverter i Cendrós, David (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Saraiva, Maria Joao (Instituto de Investigação e Inovação em Saúde da Universidade do Porto) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
More than a hundred different Transthyretin (TTR) mutations are associated with fatal systemic amyloidoses. They destabilize the protein tetrameric structure and promote the extracellular deposition of TTR as pathological amyloid fibrils. [...]
2017 - 10.1038/srep44709
Scientific reports, Vol. 7 (2017) , art. 44709  
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8.
13 p, 4.1 MB Relevant elements of a Maize γ-zein domain involved in protein body biogenesis / Llop-Tous, Immaculada (Centre de Recerca en Agrigenòmica) ; Madurga, Sergio (Universitat de Barcelona. Departament de Química Física) ; Giralt, Ernest (Institut de Recerca Biomèdica de Lleida) ; Marzabal, Pablo (ERA Biotech) ; Torrent, Margarita (Centre de Recerca en Agrigenòmica) ; Ludevid, M. Dolors (Centre de Recerca en Agrigenòmica)
The N-terminal proline-rich domain of γ-zein (Zera) plays an important role in protein body (PB) formation not only in the original host (maize seeds) but in a broad spectrum of eukaryotic cells. However, the elements within the Zera sequence that are involved in the biogenesis of PBs have not been clearly identified. [...]
2010 - 10.1074/jbc.M110.116285
Journal of biological chemistry, Vol. 285, Issue 46 (November 2010) , p. 35633-35644  
Registre complet -
9.
18 p, 3.1 MB Structural lesions of proteins connected to lipid membrane damages caused by radical stress : assessment by biomimetic systems and raman spectroscopy / Torreggiani, Armida (CNR-Istituto per la Sintesi Organica e la Fotoreattività) ; Tinti, Anna (Università di Bologna. Dipartimento di Scienze Biomediche e Neuromotorie) ; Jurasekova, Zuzana (P.J. Šafárik University. Department of Biophysics) ; Capdevila Vidal, Mercè (Universitat Autònoma de Barcelona. Departament de Química) ; Saracino, Michela (CNR-Istituto per la Sintesi Organica e la Fotoreattività) ; Di Foggia, Michele (Università di Bologna. Dipartimento di Scienze Biomediche e Neuromotorie)
Model systems constituted by proteins and unsaturated lipid vesicles were used to gain more insight into the effects of the propagation of an initial radical damage on protein to the lipid compartment. [...]
2019 - 10.3390/biom9120794
Biomolecules, Vol. 9, issue 12 (Dec. 2019) , art. 794  
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10.
7 p, 899.7 KB Common features in the unfolding and misfolding of PDZ domains and beyond : the modulatory effect of domain swapping and extra-elements / Murciano Calles, Javier (Universidad de Granada. Departamento de Química Física) ; Güell Bosch, Jofre (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Villegas Hernández, Sandra (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Martínez, José C. (Universidad de Granada. Departamento de Química Física)
PDZ domains are protein-protein interaction modules sharing the same structural arrangement. To discern whether they display common features in their unfolding/misfolding behaviour we have analyzed in this work the unfolding thermodynamics, together with the misfolding kinetics, of the PDZ fold using three archetypical examples: the second and third PDZ domains of the PSD95 protein and the Erbin PDZ domain. [...]
2016 - 10.1038/srep19242
Scientific reports, Vol. 6 (January 2016) , art. 19242  
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Articles : 11 registres trobats   1 - 10següent  anar al registre:
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