Results overview: Found 149 records in 0.02 seconds.
Articles, 117 records found
Research literature, 32 records found
Articles 117 records found  1 - 10nextend  jump to record:
1.
13 p, 14.7 MB Rice seeds as biofactories of rationally designed and cell-penetrating antifungal PAF peptides / Bundó Barberà, Mireia (Centre de Recerca en Agrigenòmica) ; Shi, Xiaoqing (Centre de Recerca en Agrigenòmica) ; Vernet Tomàs, Maria del Mar (Centre de Recerca en Agrigenòmica) ; Marcos, Jose F. (Instituto de Agroquímica y Tecnología de Alimentos) ; López García, Belén (Centre de Recerca en Agrigenòmica) ; Coca López, María (Centre de Recerca en Agrigenòmica)
PAFs are short cationic and tryptophan-rich synthetic peptides with cell-penetrating antifungal activity. They show potent and selective killing activity against major fungal pathogens and low toxicity to other eukaryotic and bacterial cells. [...]
2019 - 10.3389/fpls.2019.00731
Frontiers in plant science, Vol. 10 (June 2019) , art. 731  
2.
12 p, 710.3 KB Pazopanib : Evidence review and clinical practice in the management of advanced renal cell carcinoma / Méndez-Vidal, María José (Hospital Reina Sofía, Córdoba) ; Molina, Áurea (Complejo Hospitalario Universitario A Coruña) ; Anido, Urbano (Complejo Hospitalario Universitario de Santiago) ; Chirivella, Isabel (Hospital Clínico Universitario de Valencia) ; Etxaniz, Olatz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Fernández-Parra, Eva (Hospital Nuestra Señora del Valme) ; Guix, Marta (Hospital del Mar) ; Hernández, Carolina (Hospital Universitario Nuestra Señora de Candelaria) ; Lambea, Julio (Hospital Clínico Universitario Lozano Blesa) ; Montesa, Álvaro (Hospital Regional de Málaga) ; Pinto, Álvaro (Hospital la Paz) ; Ros, Silverio (Hospital Universitario Virgen de la Arrixaca) ; Gallardo, Enrique (Parc Taulí Hospital Universitari) ; Universitat Autònoma de Barcelona
Pazopanib is indicated in the first-line treatment of metastatic renal cell cancer (mRCC). The aim of this study was to review the efficacy, safety, and pharmacokinetics of pazopanib and see how these aspects are linked to clinical practice. [...]
2018 - 10.1186/s40360-018-0264-8
BMC Pharmacology & Toxicology, Vol. 19 (november 2018)  
3.
12 p, 1.5 MB Altered characteristics of silica nanoparticles in bovine and human serum : The importance of nanomaterial characterization prior to its toxicological evaluation / Izak-Nau, Emilia (University of Salzburg. Department of Molecular Biology) ; Voetz, Matthias (Bayer Technology Services GmbH) ; Eiden, Stefanie (Bayer Technology Services GmbH) ; Duschl, Albert (University of Salzburg. Department of Molecular Biology) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia)
Background: Many toxicological studies on silica nanoparticles (NPs) have been reported, however, the literature often shows various conclusions concerning the same material. This is mainly due to a lack of sufficient NPs characterization as synthesized as well as in operando. [...]
2013 - 10.1186/1743-8977-10-56
Particle and fibre toxicology, Vol. 10 (November 2013) , art. 56  
4.
27 p, 1.1 MB Early sepsis diagnosis via protein and miRNA biomarkers using a novel point-of-care photonic biosensor / Fabri Faja, Nuria (Institut Català de Nanociència i Nanotecnologia) ; Calvo Lozano, Olalla (Institut Català de Nanociència i Nanotecnologia) ; Dey, Priyanka (Institut Català de Nanociència i Nanotecnologia) ; Terborg, Roland A. (ICFO—Institut de Ciències Fotòniques) ; Estévez Alberola, Maria Carmen (Institut Català de Nanociència i Nanotecnologia) ; Belushkin, Alexander (École Polytechnique Fédérale de Lausanne) ; Yesilköy, Filiz (École Polytechnique Fédérale de Lausanne) ; Duempelmann, Luc (ICFO—Institut de Ciències Fotòniques) ; Altug, Hatice (École Polytechnique Fédérale de Lausanne) ; Pruneri, Valerio (Institució Catalana de Recerca i Estudis Avançats) ; Lechuga, Laura M. (Institut Català de Nanociència i Nanotecnologia)
Sepsis is a condition characterized by a severe stage of blood-infection often leading to tissue damage, organ failure and finally death. Fast diagnosis and identification of the sepsis stage (sepsis, severe sepsis or septic shock) is critical for the patient's evolution and could help in defining the most adequate treatment in order to reduce its mortality. [...]
2019 - 10.1016/j.aca.2019.05.038
Analytica chimica acta, Vol. 1077 (October 2019) , p. 232-242  
5.
Control of plastidial metabolism by the Clp protease complex / Rodríguez Concepción, Manuel (Centre de Recerca en Agrigenòmica) ; D'Andrea, Lucio (Centre de Recerca en Agrigenòmica) ; Pulido, Pablo (Centre de Recerca en Agrigenòmica)
Plant metabolism is strongly dependent on plastids. Besides hosting the photosynthetic machinery, these endosymbiotic organelles synthesize starch, fatty acids, amino acids, nucleotides, tetrapyrroles, and isoprenoids. [...]
2019 - 10.1093/jxb/ery441
Journal of experimental botany, Vol. 70, Issue 7 (March 2019) , p. 2049-2058  
6.
8 p, 2.5 MB Protein-Corona-by-Design in 2D : A Reliable Platform to Decode Bio–Nano Interactions for the Next-Generation Quality-by-Design Nanomedicines / Mei, Kuo‐Ching (King's College London) ; Ghazaryan, Artur (Max Planck Institute for Polymer Research) ; Teoh, Er Zhen (King's College London) ; Summers, Huw D. (Swansea University) ; Li, Yueting (Guizhou Medical University) ; Ballesteros, Belén (Institut Català de Nanociència i Nanotecnologia) ; Piasecka, Justyna (Swansea University) ; Walters, Adam (King's College London) ; Hider, Robert C. (King's College London) ; Mailänder, Volker (Johannes Gutenberg-University. Department of Dermatology) ; Al-Jamal, Khuloud T. (King's College London)
Hard corona (HC) protein, i. e. , the environmental proteins of the biological medium that are bound to a nanosurface, is known to affect the biological fate of a nanomedicine. Due to the size, curvature, and specific surface area (SSA) 3-factor interactions inherited in the traditional 3D nanoparticle, HC-dependent bio–nano interactions are often poorly probed and interpreted. [...]
2018 - 10.1002/adma.201802732
Advanced materials, Vol. 30, Issue 40 (October 2018) , art. 1802732  
7.
9 p, 7.2 MB Low-cost and portable UV holographic microscope for high-contrast protein crystal imaging / Daloglu, Mustafa Ugur (University of California) ; Ray, Aniruddha (University of California) ; Collazo, Michael J. (University of California) ; Brown, Calvin (University of California) ; Tseng, Derek (University of California) ; Chocarro Ruiz, Blanca (Institut Català de Nanociència i Nanotecnologia) ; Lechuga, Laura M. (Institut Català de Nanociència i Nanotecnologia) ; Cascio, Duilio (University of California) ; Ozcan, Aydogan (University of California)
Imaging protein crystals and distinguishing them from salt crystals is an important task for protein crystallographers. The conventional tool used for this purpose is a dual-mode microscope composed of bright-field and ultraviolet (UV) induced fluorescence modes. [...]
2019 - 10.1063/1.5080158
APL Photonics, Vol. 4, Issue 3 (March 2019) , art. 30804  
8.
8 p, 985.7 KB Analysis of alternative splicing events for cancer diagnosis using a multiplexing nanophotonic biosensor / Sánchez Huertas, César (Institut Català de Nanociència i Nanotecnologia) ; Domínguez Zotes, Santos (Institut Català de Nanociència i Nanotecnologia) ; Lechuga, Laura M. (Institut Català de Nanociència i Nanotecnologia)
Personalized medicine is a promising tool not only for prevention, screening and development of more efficient treatment strategies, but also for diminishing the side effects caused by current therapies. [...]
2017 - 10.1038/srep41368
Scientific reports, Vol. 7 (January 2017) , art. 41368  
9.
10 p, 342.2 KB New set of 2D/3D thermodynamic indices for proteins. A formalism based on "Molten Globule" theory / Ruiz Blanco, Yasser B. (Central University of Las Villas. Unit of Computer-Aided Molecular Biosilico Discovery and Bioinformatic Research (Cuba)) ; García, Yamila (Centre d'Investigació en Nanociència i Nanotecnologia) ; Sotomayor Torres, Clivia M. (Centre d'Investigació en Nanociència i Nanotecnologia) ; Marrero Ponce, Yovani (Central University of Las Villas. Unit of Computer-Aided Molecular Biosilico Discovery and Bioinformatic Research (Cuba))
We define eight new macromolecular indices, and several related descriptors for proteins. The coarse grained methodology used for its deduction ensures its fast execution and becomes a powerful potential tool to explore large databases of protein structures. [...]
2010 - 10.1016/j.phpro.2010.10.013
Physics Procedia, Vol. 8 (March 2010) , p. 63-72  
10.
10 p, 290.8 KB Alectinib versus crizotinib in untreated ALK-positive non–small-cell lung cancer / Peters, S. (Lausanne University Hospital) ; Camidge, D.R. (University of Colorado) ; Shaw, A.T. (Massachusetts General Hospital) ; Gadgeel, S. (University of Michigan) ; Ahn, J.S. (Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Kim, D.W. (Seoul National University Hospital) ; Ou, S.H.I. (School of Medicine) ; Pérol, M. (Department of Medical Oncology. Léon Bérard Cancer Center) ; Dziadziuszko, R. (Department of Oncology and Radiotherapy. Medical University of Gdansk) ; Rosell, R. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Zeaiter, A. (F. Hoffmann–La Roche) ; Mitry, E. (F. Hoffmann–La Roche) ; Golding, S. (F. Hoffmann–La Roche) ; Balas, B. (F. Hoffmann–La Roche) ; Noe, J. (F. Hoffmann–La Roche) ; Morcos, P.N. (Roche Innovation Center) ; Mok, T. (State Key Laboratory of South China. Chinese University of Hong Kong)
BACKGROUND: Alectinib, a highly selective inhibitor of anaplastic lymphoma kinase (ALK), has shown systemic and central nervous system (CNS) efficacy in the treatment of ALK-positive non–small-cell lung cancer (NSCLC). [...]
2017 - 10.1056/NEJMoa1704795
New England Journal of Medicine, Vol. 377 Núm. 9 (31 2017) , p. 829-838  

Articles : 117 records found   1 - 10nextend  jump to record:
Research literature 32 records found  1 - 10nextend  jump to record:
1.
Development of bioinformatic tools for the study of membrane proteins. / Mayol Escuer, Eduardo, autor. ; Cordomí Montoya, Arnau, supervisor acadèmic. ; Olivella, Mireia, supervisor acadèmic. ; Duñach i Masjuan, Mireia, supervisor acadèmic. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular.
Las proteínas de membrana son elementos fundamentales de todas las células conocidas, que representan una cuarta parte de los genes del genoma humano, y desempeñan funciones esenciales en la biología celular. [...]
Membrane proteins are fundamental elements for every known cell, accounting for a quarter of genes in the Human genome, they play essential roles in cell biology. About 50% of currently marketed drugs have a membrane protein as target, and around a third of them target G-protein-coupled receptors (GPCRs). [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2019.  
2.
1 p, 10.8 MB Deciphering hIAPP : a novel way to cure diabetes / Ruiz López, Iñigo ; Pallarés Goitiz, Irantzu, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
Human islet amyloid polypeptide (hIAPP) is produced by pancreatic β-cells and is involved in type-II diabetes mellitus (T2DM) pathogenesis. In T2DM, the loss of pancreatic β-cell mass is accompanied by the accumulation of amyloid deposits of hIAPP. [...]
2019-05-29
Graduat o graduada en Biotecnologia [815]  
3.
1 p, 5.7 MB Hypertrophic cardiomyopathy : characterization and treatments for one of the diseases that more deaths generates / Llamas de Castro, Ana M. ; Universitat Autònoma de Barcelona. Facultat de Biociències
2018
Graduat o Graduada en Bioquímica [814]  
4.
1 p, 526.3 KB The design of proteins that switch folds upon stimulation / Rehues Masip, Pere ; Vendrell i Roca, Josep, dir., (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2017
Graduat o Graduada en Biotecnologia [815]  
5.
227 p, 7.0 MB Estudi del paper de la proteïna quinasa CK2 en l'inici de la traducció de proteïnes i de la seva associació a microdominis de la membrana cel·lular / Falqués Costa, Antoni, autor ; Gil Giró, Carles, supervisor acadèmic (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
La proteïna quinasa CK2 és una serina treonina quinasa que s'expressa ubiquament a la cèl·lula i de manera pleiotròpica en humans, és constitutivament activa i se n'han descrit més d'un centenar de substrats. [...]
The protein kinase CK2 is a serine threonine kinase that is expressed ubiquitously along the cell and in pleiotropic manner in humans, it is constitutively active and more than one hundred substrates has been described. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2017  
6.
1 p, 14.3 MB Computational-aided drug discovery in protein-protein interactions : defining a simple protocol and testing it in Notch signaling / Montava Garriga, Lambert ; Maréchal, Jean-Didier, dir. (Universitat Autònoma de Barcelona. Departament de Química) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Biotecnologia [815]  
7.
1 p, 965.0 KB Blastic transformation in chronic myeloid leukemia : the BCR-ABL protein, telomerases and telomerase / Camenforte Castaño, Néstor ; Tusell Padrós, Laura, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Genètica [833]  
8.
1 p, 410.9 KB DJ-1, a possible therapeutic target against Parkinson's disease / Oliva Vilarnau, Núria ; Yuste Mateos, Víctor J., (Víctor José), dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Biotecnologia [815]  
9.
164 p, 12.2 MB Design of protein nanoparticles for cell targeting and blood brain barrier crossing / Xu, Zhikun ; Ferrer Miralles, Neus, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
En estos últimos años, muchos nuevos materiales han sido involucrados en los campos de las nanotecnologías, y especialmente en nanomedicina. Las nanoparticulas formadas por proteínas son un ejemplo de bio-material que está atrayendo cada vez más la atención debido a sus características tanto biológicas como estructurales, como por ekjemplo su baja toxicidad, baja inmunogenicidad y su biodegradabilidad. [...]
With the development of nanotechnology and nanomedicine, more and more materials have been involved in these fields, protein based nanoparticles have become another biomaterial that is developing fast and attracts growing attention. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2015  
10.
153 p, 2.0 MB Structural studies on protein-protein interactions: Analysis of the regulation of the DYNLL/LC8 binding to Nek9 and characterization of the enzymes composing the arginine deiminase pathway in mycoplasma penetrans / Gallego Alonso, Pablo ; Reverter i Cendrós, David, dir. (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Las interacciones proteína-proteína (PPIs, por sus siglas en inglés) son contactos físicos intencionados que se dan entre dos o más proteínas. Estas interacciones forman la red de interacciones de proteínas y forman el núcleo del sistema interatómica de toda célula viva. [...]
Protein-Protein Interactions (PPIs) are intentional physical contacts established between two or more proteins. These interactions form the large protein interaction network and are the core of the entire interatomic system of any living cell. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2015  

Research literature : 32 records found   1 - 10nextend  jump to record:
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