Resultados globales: 3 registros encontrados en 0.02 segundos.
Artículos, Encontrados 3 registros
Artículos Encontrados 3 registros  
1.
15 p, 620.2 KB Endometrial gene expression profile of pregnant sows with extreme phenotypes for reproductive efficiency / Córdoba, Sarai (Centre de Recerca en Agrigenòmica) ; Balcells Ortega, Ingrid (Centre de Recerca en Agrigenòmica) ; Castelló, Anna (Centre de Recerca en Agrigenòmica) ; Ovilo, Cristina (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria) ; Noguera Jiménez, José Luis (Institut de Recerca i Tecnologia Agroalimentàries) ; Timoneda i Heredia, Oriol (Centre de Recerca en Agrigenòmica) ; Sánchez Bonastre, Armando (Centre de Recerca en Agrigenòmica) ; Universitat Autònoma de Barcelona. Departament de Genètica Animal
2015 0) and low (L, EBV 0) prolificacy phenotypes. For each sample, mRNA and small RNA libraries were RNA-sequenced, identifying 141 genes and 10 miRNAs differentially expressed between H and L groups. We selected four miRNAs based on their role in reproduction, and five genes displaying the highest differences and a positive mapping into known reproductive QTLs for RT-qPCR validation on the whole extreme population. Significant differences were validated for genes: PTGS2 (p = 0.03; H/L ratio = 3.50), PTHLH (p = 0.03; H/L ratio = 3.69), MMP8 (p = 0.01; H/L ratio = 4.41) and SCNN1G (p = 0.04; H/L ratio = 3.42). Although selected miRNAs showed similar expression levels between H and L groups, significant correlation was found between the expression level of ssc-miR-133a (p 0.01) and sscmiR-92a (p 0.01) and validated genes. These results provide a better understanding of the genetic architecture of prolificacy-related traits and embryo implantation failure in pigs. - 10.1038/srep14416
Scientific reports, Vol. 5 (October 2015) , art. 14416  
2.
13 p, 1.8 MB Expression analysis of candidate genes for fatty acid composition in adipose tissue and identification of regulatory regions / Revilla, Manuel (Centre de Recerca en Agrigenòmica) ; Puig-Oliveras, Anna (Centre de Recerca en Agrigenòmica) ; Crespo-Piazuelo, Daniel (Centre de Recerca en Agrigenòmica) ; Criado Mesas, Lourdes (Centre de Recerca en Agrigenòmica) ; Castelló, Anna (Centre de Recerca en Agrigenòmica) ; Fernández Ávila, Ana Isabel (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria) ; Ballester Devis, Maria (Institut de Recerca i Tecnologia Agroalimentàries) ; Folch Albareda, Josep Maria (Centre de Recerca en Agrigenòmica)
The aim of this work was to study the genetic basis of the backfat expression of lipid-related genes associated with meat quality traits in pigs. We performed a genome-wide association study with the backfat gene expression measured in 44 genes by qPCR and the PorcineSNP60 BeadChip genotypes in 115 Iberian x Landrace backcross animals. [...]
2018 - 10.1038/s41598-018-20473-3
Scientific reports, Vol. 8 (February 2018) , art. 2045  
3.
21 p, 2.1 MB Natural Polymorphisms in Tap2 Influence Negative Selection and CD4:CD8 Lineage Commitment in the Rat / Tuncel, Jonatan (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Haag, Sabrina (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Yau, Anthony C. (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Norin, Ulrika (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Baud, Amelie (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Lönnblom, Erik (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Maratou, Klio (Imperial College London) ; Ytterberg, A. Jimmy (Karolinska University Hospital) ; Ekman, Diana (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Thordardottir, Soley (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Johannesson, Martina (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Gillett, Alan (Karolinska University Hospital) ; Stridh, Pernilla (Karolinska University Hospital) ; Jagodic, Maja (Karolinska University Hospital) ; Olsson, Tomas (Karolinska University Hospital) ; Fernández-Teruel, Albert (Universitat Autònoma de Barcelona. Departament de Psiquiatria i Medicina Legal) ; Zubarev, Roman A. (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Mott, Richard (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Aitman, Timothy J. (Imperial College London) ; Flint, Jonathan (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Holmdahl, Rikard (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; EURATRANS Consortium
Genetic variation in the major histocompatibility complex (MHC) affects CD4∶CD8 lineage commitment and MHC expression. However, the contribution of specific genes in this gene-dense region has not yet been resolved. [...]
2014 - 10.1371/journal.pgen.1004151
PLoS Genetics, Vol. 10 Issue 2 (February 2014) , p. e1004151  

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