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11 p, 330.9 KB |
Asthma control conundrum in clinical practice - Data from a two-stage Delphi survey and literature review
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Canonica, G. Walter (Humanitas University) ;
Spanevello, Antonio (Università degli Studi dell'Insubria) ;
Pérez de Llano, Luis (University Hospital Lucus Augusti (Lugo, Galícia)) ;
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Blakey, John D (Curtin University) ;
Garcia, Gabriel (Hospital R Rossi) ;
Inoue, Hiromasa (Kagoshima University) ;
Dalcolmo, Margareth (Reference Center Hélio Fraga) ;
Yang, Dong (Fudan University) ;
Mokashi, Soniya (GlaxoSmithKline) ;
Kurne, Abhishek (Global Medical Affairs) ;
Butta, Aman Kapil (GSK Asia House) ;
Universitat Autònoma de Barcelona
Definitions and measures of asthma control used in clinical trials and practice often vary, as highlighted in the manuscript, "Is asthma control more than just an absence of symptoms? An expert consensus statement". [...]
2023 -  10.1016/j.dib.2023.109422
Data in brief, Vol. 50 (july 2023)
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48 p, 903.4 KB |
Online consumption and inequality in Spain : are new forms of fragmentation emerging?
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Barbeta Viñas, Marc (Universitat Autònoma de Barcelona.) ;
Sanchez Gelabert, Albert (Universitat Autònoma de Barcelona.)
En los últimos años el consumo digital, muy en particular el realizado en plataformas de consumo, está viviendo un crecimiento de gran relevancia que está transformando los mercados de consumo. Sin embargo, no existen demasiados trabajos sociológicos que aporten conocimiento acerca de cómo se está desarrollando dicho proceso. [...]
Digital consumption, particularly on consumer platforms, has seen major growth in recent years and has transformed consumer markets. However, little sociological research has been conducted that provides insight into how this process is unfolding. [...]
2023 - 10.5477/cis/reis.184.23
Revista española de investigaciones sociológicas, Núm. 184 (2023) , p. 23-45
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3.
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15 p, 1.1 MB |
A quantitative approach to the understanding of social-ecological systems : a case study from the Pyrenees
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Zango Palau, Anna (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Jolivet, Anaïs (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Lurgi Rivera, Miguel (Swansea University. Department of Biosciences) ;
Claramunt López, Bernat (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
Mountains are social-ecological systems exposed to multiple climatic and socioeconomic drivers. The Pyrenees are a clear example of the concomitant challenges that these regions face, as they are exposed to stressors linked to depopulation, an economic shift towards tourism, and climate change. [...]
2024 - 10.1007/s10113-023-02177-1
Regional environmental change, Vol. 24, Issue 1 (March 2024) , art. 9
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14 p, 8.0 MB |
Three-year quantitative magnetic resonance imaging and phosphorus magnetic resonance spectroscopy study in lower limb muscle in dysferlinopathy
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Reyngoudt, Harmen (NMR Laboratory) ;
Smith, Fiona Elizabeth (Newcastle University) ;
Caldas de A. Araújo, Ericky (NMR Laboratory) ;
Wilson, Ian (Newcastle University) ;
Fernandez-Torron, Roberto (Hospital de Donostia (Sant Sebastià, País Basc)) ;
James, Meredith K. (Newcastle University) ;
Moore, Ursula (Newcastle University) ;
Diaz-Manera, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Marty, Benjamin (NMR Laboratory) ;
Azzabou, Noura (NMR Laboratory) ;
Gordish-Dressman, Heather (George Washington University) ;
Rufibach, Laura E. (The JAIN Foundation) ;
Hodgson, Tim (Newcastle University) ;
Wallace, Dorothy (Newcastle University) ;
Ward, Louise (Newcastle University) ;
Boisserie, Jean Marc (NMR Laboratory) ;
Le Louër, Julien (NMR Laboratory) ;
Hilsden, Heather (Newcastle University) ;
Sutherland, Helen (Newcastle University) ;
Canal, Aurélie (Institute of Myology) ;
Hogrel, J.Y (Institut de Myologie (París, França)) ;
Jacobs, Marni (George Washington University) ;
Stojkovic, Tanya (Institut deMyologie (París, França)) ;
Bushby, Kate (Newcastle University) ;
Mayhew, Anna G. (Newcastle University) ;
Straub, Volker (Newcastle University) ;
Carlier, Pierre G. (University Paris-Saclay) ;
Blamire, Andrew (Newcastle University) ;
Universitat Autònoma de Barcelona
Natural history studies in neuromuscular disorders are vital to understand the disease evolution and to find sensitive outcome measures. We performed a longitudinal assessment of quantitative magnetic resonance imaging (MRI) and phosphorus magnetic resonance spectroscopy (P MRS) outcome measures and evaluated their relationship with function in lower limb skeletal muscle of dysferlinopathy patients. [...]
2022 - 10.1002/jcsm.12987
Journal of Cachexia, Sarcopenia and Muscle, Vol. 13 Núm. 3 (june 2022) , p. 1850-1863
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9 p, 1.9 MB |
Effect of Sirolimus Exposure on the Need for Preemptive Antiviral Therapy for Cytomeglovirus Infection after Allogeneic Hematopoietic Stem Cell Transplantation
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Guglieri-Lopez, Beatriz (Hospital Universitari Doctor Peset (València)) ;
Perez-Pitarch, Alejandro (Hospital Clínico Universitario de València) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Gimenez, Estela (Hospital Clínico Universitario de València) ;
Barba, Pere (Hospital Universitari Vall d'Hebron) ;
Rabella, Núria (Institut d'Investigació Biomèdica Sant Pau) ;
Hernandez-Boluda, Juan Carlos (Hospital Clínico Universitario de València) ;
Fox, Maria Laura (Hospital Universitari Vall d'Hebron) ;
Valcárcel, David (Hospital Universitari Vall d'Hebron) ;
Esquirol, Albert (Institut d'Investigació Biomèdica Sant Pau) ;
Ferriols-Lisart, Rafael (Hospital Clínico Universitario de València) ;
Sierra, Jorge (Institut d'Investigació Biomèdica Sant Pau) ;
Solano, Carlos (Universitat de València) ;
Navarro, David (Universitat de València) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Piñana, José Luis (Instituto de Salud Carlos III) ;
Universitat Autònoma de Barcelona
The current study evaluates the clinical effect of sirolimus exposure on the occurrence of cytomegalovirus (CMV)DNAemia necessitating preemptive antiviral therapy. A total of 167 consecutive recipients of reduced-intensity conditioning (RIC)allogeneic hematopoietic stem cell transplantation (allo-HSCT)who received sirolimus- and tacrolimus-based graft-versus-host disease (GVHD)prophylaxis and whose CMV serostatus was positive for donors and/or recipients were included in this multicenter retrospective study. [...]
2019 - 10.1016/j.bbmt.2019.01.012
Biology of blood and marrow transplantation, Vol. 25 Núm. 5 (may 2019) , p. 1022-1030
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0 p, 2.2 MB |
The identification of intrinsic chloramphenicol and tetracycline resistance genes in members of the bacillus cereus group (sensu lato)
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Glenwright, Helen (Newcastle University. Institute for Cell and Molecular Biology) ;
Pohl, Susanne (Newcastle University. Institute for Cell and Molecular Biology) ;
Navarro Risueño, Ferran (Institut d'Investigació Biomèdica Sant Pau) ;
Miró, Elisenda (Institut d'Investigació Biomèdica Sant Pau) ;
Jiménez, Guillermo (Rubinum, S.A. Research and Development Department) ;
Blanch Gisbert, Anicet Ramon (Universitat de Barcelona. Departament de Microbiologia) ;
Harwood, Colin R. (Newcastle University. Institute for Cell and Molecular Biology)
Bacillus toyonensis strain BCT-7112T (NCIMB 14858T) has been widely used as an additive in animal nutrition for more than 30 years without reports of adverse toxigenic effects. However, this strain is resistant to chloramphenicol and tetracycline and it is generally considered inadvisable to introduce into the food chain resistance determinants capable of being transferred to other bacterial strains, thereby adding to the pool of such determinants in the gastro-enteric systems of livestock species. [...]
2017 - 10.3389/fmicb.2016.02122
Frontiers in microbiology, Vol. 7 (January 2017) , art. 2122
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13 p, 2.5 MB |
Integrated GWAS and Gene Expression Suggest ORM1 as a Potential Regulator of Plasma Levels of Cell-Free DNA and Thrombosis Risk
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López, Sonia (Institut d'Investigació Biomèdica Sant Pau) ;
Martinez-Perez, Angel (Institut d'Investigació Biomèdica Sant Pau) ;
Rodriguez-Rius, Alba (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Viñuela, Ana (Biosciences Institute. Faculty of Medicine. Newcastle University) ;
Brown, Andrew A. (Population Health and Genomics. University of Dundee) ;
Martin-Fernandez, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vilalta, Noelia (Institut d'Investigació Biomèdica Sant Pau) ;
Arús, Marc (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Panousis, Nikolaos I. (Department of Genetic Medicine and Development. University of Geneva) ;
Buil, Alfonso (Institute of Biological Psychiatry. Mental Health Sct. Hans Hospital) ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Souto, Juan Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Dermitzakis, Emmanouil T (University of Geneva Medical School) ;
Soria Fernández, José Manuel (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Plasma cell-free DNA (cfDNA) is a surrogate marker of neutrophil extracellular traps (NETs) that contribute to immunothrombosis. There is growing interest about the mechanisms underlying NET formation and elevated cfDNA, but little is known about the factors involved. [...]
2022 - 10.1055/s-0041-1742169
Thrombosis and Haemostasis, Vol. 122 Núm. 6 (january 2022) , p. 1027-1039
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6 p, 977.9 KB |
Detection of cytomegalovirus in bronchoalveolar lavage fluid from immunocompromised patients with pneumonitis by viral culture and DNA quantification
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Berengua, Carla (Institut d'Investigació Biomèdica Sant Pau) ;
Miró, Elisenda (Institut d'Investigació Biomèdica Sant Pau) ;
Gutiérrez, C. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sánchez, M. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Mulero, A. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Ramos, P. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
del Cuerpo, Margarita (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Torrego, A. (Institut d'Investigació Biomèdica Sant Pau) ;
García-Cadenas, I. (Institut d'Investigació Biomèdica Sant Pau) ;
Pajares Ruiz, Virginia (Institut d'Investigació Biomèdica Sant Pau) ;
Navarro Risueño, Ferran (Institut d'Investigació Biomèdica Sant Pau) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Rabella, N. (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
To compare the detection of human cytomegalovirus (HCMV) in bronchoalveolar lavage (BAL) fluid by viral culture and quantitative polymerase chain reaction (qPCR), and to establish a viral load threshold that can identify cases of HCMV replication indicative of pneumonitis. [...]
2023 - 10.1016/j.jviromet.2023.114743
Journal of Virological Methods, Vol. 317 (2023) , p. 114743
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13 p, 2.1 MB |
Magnetic Bead Handling Using a Paper-Based Device for Quantitative Point-of-Care Testing
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Arias-Alpízar, Kevin (Hospital Universitari Vall d'Hebron) ;
Sánchez-Cano, Ana (Hospital Universitari Vall d'Hebron) ;
Prat-Trunas, Judit (Hospital Universitari Vall d'Hebron) ;
Sulleiro Igual, Elena (Hospital Universitari Vall d'Hebron) ;
Bosch-Nicolau, Pau (Hospital Universitari Vall d'Hebron) ;
Salvador, Fernando (Hospital Universitari Vall d'Hebron) ;
Oliveira, Inés (Hospital Universitari Vall d'Hebron) ;
Molina Romero, Israel (Hospital Universitari Vall d'Hebron) ;
Sánchez-Montalvá, Adrián (Hospital Universitari Vall d'Hebron) ;
Baldrich Rubio, Eva (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Microfluidic paper-based analytical devices (μPADs) have been extensively proposed as ideal tools for point-of-care (POC) testing with minimal user training and technical requirements. However, most μPADs use dried bioreagents, which complicate production, reduce device reproducibility and stability, and require transport and storage under temperature and humidity-controlled conditions. [...]
2022 - 10.3390/bios12090680
Biosensors, Vol. 12 (august 2022)
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