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12 p, 2.3 MB |
Effect of Low-Dose Radiotherapy on the Circulating Levels of Paraoxonase-1-Related Variables and Markers of Inflammation in Patients with COVID-19 Pneumonia
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Rodríguez-Tomàs, Elisabet (Institut d'Investigació Sanitària Pere Virgili) ;
Acosta, Johana C. (Institut d'Investigació Sanitària Pere Virgili) ;
Torres-Royo, Laura (Institut d'Investigació Sanitària Pere Virgili) ;
De Febrer, Gabriel (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Baiges-Gaya, Gerard (Institut d'Investigació Sanitària Pere Virgili) ;
Castañé, Helena (Institut d'Investigació Sanitària Pere Virgili) ;
Jiménez, Andrea (Institut d'Investigació Sanitària Pere Virgili) ;
Vasco, Carlos (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Araguas, Pablo (Institut d'Investigació Sanitària Pere Virgili) ;
Gómez, Junior (Institut d'Investigació Sanitària Pere Virgili) ;
Malave, Bárbara (Institut d'Investigació Sanitària Pere Virgili) ;
Árquez, Miguel (Institut d'Investigació Sanitària Pere Virgili) ;
Calderón, David (Institut d'Investigació Sanitària Pere Virgili) ;
Piqué, Berta (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Algara, Manuel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Montero, Ángel (Hospital Universitario HM Sanchinarro (Madrid)) ;
Simó, Josep M. (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Gabaldó-Barrios, Xavier (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Sabater, Sebastià (Complejo Hospitalario Universitario de Albacete) ;
Camps, Jordi (Institut d'Investigació Sanitària Pere Virgili) ;
Joven, Jorge (Institut d'Investigació Sanitària Pere Virgili) ;
Arenas, Meritxell (Institut d'Investigació Sanitària Pere Virgili) ;
Universitat Autònoma de Barcelona
The aim of our study was to investigate the changes produced by low-dose radiotherapy (LDRT) in the circulating levels of the antioxidant enzyme paraoxonase-1 (PON1) and inflammatory markers in patients with COVID-19 pneumonia treated with LDRT and their interactions with clinical and radiological changes. [...]
2022 -  10.3390/antiox11061184
Antioxidants, Vol. 11 (june 2022)
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38 p, 835.8 KB |
Comparison of X-ray dose-response curves obtained by chromosome painting using conventional and PAINT nomenclatures
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Barquinero, Joan Francesc (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Cigarrán Valea, Sergio (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Caballín, M. R. (María Rosa) (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Braselmann, H. (GSF, National Research Center for Environment and Health, Institute of Radiobiology) ;
Ribas, Montserrat (Institut d'Investigació Biomèdica Sant Pau) ;
Egozcue, Josep 1940-2006 (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Barrios, Leonardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Purpose: The compare the suitability of PAINT and conventional nomenclature systems for the construction of chromosome aberration dose- effect curves for X-rays using FISH techniques, and to compare these curves with those based on solid-stained dicentrics analysed in first division metaphases by the FPG technique. [...]
1999 - 10.1080/095530099139160
International Journal of Radiation Biology, Vol. 75 Núm. 12 (1999) , p. 1557-1566
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3.
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36 p, 800.8 KB |
Establishment and validation of surface model for biodosimetry based on γ-H2AX foci detection
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López Vásquez, Juan Sebastián (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Pujol Canadell, Mònica (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Puig, Pedro (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ;
Ribas, Montserrat (Institut d'Investigació Biomèdica Sant Pau) ;
Carrasco de Fez, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
Armengol Rosell, Gemma (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Barquinero, Joan Francesc (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
Introduction: In the event of a radiation accident detecting γ-H2AX foci is being accepted as fast method for triage and dose assessment. However, due to their disappearance kinetics, published calibrations have been constructed at specific post-irradiation times. [...]
2022 - 10.1080/09553002.2022.1998706
International Journal of Radiation Biology, Vol. 98, Issue 1 (2022) , p. 1-10
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22 p, 2.4 MB |
Low dose ionizing radiation effects on the immune system
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Lumniczky, Katalin (National Public Health Centre. Department of Radiation Medicine) ;
Impens, Nathalie (Belgian Nuclear Research Centre) ;
Armengol Rosell, Gemma (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Candéias, Serge (Université Grenoble-Alpes) ;
Georgakilas, Alexandros G. (National Technical University of Athens. Physics Department) ;
Hornhardt, Sabine (Federal Office for Radiation Protection) ;
Martin, Olga A. (The University of Melbourne. Peter MacCallum Department of Oncology) ;
Rödel, Franz (Goethe University Frankfurt am Main. Department of Radiotherapy and Oncology) ;
Schaue, Dörthe (University of California at Los Angeles. Department of Radiation Oncology)
Ionizing radiation interacts with the immune system in many ways with a multiplicity that mirrors the complexity of the immune system itself: namely the need to maintain a delicate balance between different compartments, cells and soluble factors that work collectively to protect, maintain, and restore tissue function in the face of severe challenges including radiation damage. [...]
2021 - 10.1016/j.envint.2020.106212
Environment International, Vol. 149 (April 2021) , art. 106212
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11 p, 743.5 KB |
Could pulmonary low-dose radiation therapy be an alternative treatment for patients with COVID-19 pneumonia? Preliminary results of a multicenter SEOR-GICOR nonrandomized prospective trial (IPACOVID trial)
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Arenas, Manuel (Institut d'Investigació Sanitària Pere Virgili) ;
Algara, Manuel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
De Febrer, Gabriel (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Rubio, C. (HM Hospitales, Madrid) ;
Sanz, X. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
de la Casa, M. A. (HM Hospitales, Madrid) ;
Vasco, C. (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Marín, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Fernández-Letón, P.. (HM Hospitales, Madrid) ;
Villar, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Torres-Royo, L. (Institut d'Investigació Sanitària Pere Virgili) ;
Villares, P. (HM Hospitales, Madrid) ;
Membrive, I. (Hospital del Mar (Barcelona, Catalunya)) ;
Acosta, Johana (Institut d'Investigació Sanitària Pere Virgili) ;
López-Cano, Manuel (HM Hospitales, Madrid) ;
Araguas, Pablo (Institut d'Investigació Sanitària Pere Virgili) ;
Quera, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodríguez-Tomás, F. (Institut d'Investigació Sanitària Pere Virgili) ;
Montero, A. (HM Hospitales, Madrid)
Purpose: To evaluate the efficacy and safety of lung low-dose radiation therapy (LD-RT) for pneumonia in patients with coronavirus disease 2019 (COVID-19). Materials and methods: Inclusion criteria comprised patients with COVID-19-related moderate-severe pneumonia warranting hospitalization with supplemental O and not candidates for admission to the intensive care unit because of comorbidities or general status. [...]
2021 - 10.1007/s00066-021-01803-3
Strahlentherapie und Onkologie, 2021
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16 p, 4.1 MB |
Redox status, dose and antioxidant intake in healthcare workers occupationally exposed to ionizing radiation
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Sebastià, Natividad (Instituto de Investigación Sanitaria La Fe) ;
Olivares-González, Lorena (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Montoro, Alegría (Instituto de Investigación Sanitaria La Fe) ;
Barquinero, Joan Francesc (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Canyada-Martinez, Antonio José (Instituto de Investigación Sanitaria La Fe) ;
Hervas, David (Instituto de Investigación Sanitaria La Fe) ;
Gras, Pilar (Hospital Universitari i Politècnic La Fe (València)) ;
Villaescusa, Juan Ignacio (Instituto de Investigación Sanitaria La Fe) ;
Martí-Bonmatí, Luis (Hospital Universitari i Politècnic La Fe (València)) ;
Tabita Muresan, Bianca (Hospital Universitari i Politècnic La Fe (València)) ;
Soriano, José Miguel (Hospital Universitari i Politècnic La Fe (València)) ;
Campayo, Juan Manuel (Hospital Universitari i Politècnic La Fe (València)) ;
Andani, Joaquin (Hospital Universitari i Politècnic La Fe (València)) ;
Alonso, Oscar (Hospital Universitari i Politècnic La Fe (València)) ;
Rodrigo, Regina (Instituto de Investigación Sanitaria La Fe)
The purpose of this study was to evaluate the relationship between blood redox status, dose and antioxidant dietary intake of different hospital staff groups exposed to low doses of ionizing radiation (LDIR) (Interventional Radiology and Cardiology, Radiation Oncology, and Nuclear Medicine) and non-exposed. [...]
2020 - 10.3390/antiox9090778
Antioxidants, Vol. 9 , Issue 9 (September 2020) , art. 778
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11 p, 323.2 KB |
Nuclear cardiology practice and associated radiation doses in Europe : results of the IAEA Nuclear Cardiology Protocols Study (INCAPS) for the 27 European countries
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Lindner, Oliver (Institute of Radiology, Nuclear Medicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia Bochum, University Hospital of the Ruhr University, Germany) ;
Pascual, Thomas N. B. (Section of Nuclear Medicine and Diagnostic Imaging, Division of Human Health, International Atomic Energy Agency, Vienna, Austria) ;
Mercuri, Mathew (Division of Cardiology, Department of Medicine, Columbia University Medical Center and New York-Presbyterian Hospital, New York, NY USA) ;
Acampa, Wanda (Institute of Biostructures and Bioimaging, National Council of Research, Naples, Italy) ;
Burchert, Wolfgang (Institute of Radiology, Nuclear Medicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia Bochum, University Hospital of the Ruhr University, Germany) ;
Flotats, Albert (Institut d'Investigació Biomèdica Sant Pau) ;
Kaufmann, Philipp A. (University Hospital Zurich (Suïssa)) ;
Kitsiou, Anastasia (Department of Cardiology, Sismanoglio Hospital, Athens, Greece) ;
Knuuti, Juhani (Turku PET Centre, University of Turku, and Turku University Hospital, Turku, Finland) ;
Underwood, S. Richard (Royal Brompton Hospital (Londres)) ;
Vitola, João V. (Quanta Diagnóstico & Terapia, Curitiba, Brazil) ;
Mahmarian, John J. (Department of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, TX USA) ;
Karthikeyan, Ganesan (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Better, Nathan (Royal Melbourne Hospital (Melbourne, Austràlia)) ;
Rehani, Madan M. (Harvard Medical School) ;
Kashyap, Ravi (Section of Nuclear Medicine and Diagnostic Imaging, Division of Human Health, International Atomic Energy Agency, Vienna, Austria) ;
Dondi, Maurizio (Section of Nuclear Medicine and Diagnostic Imaging, Division of Human Health, International Atomic Energy Agency, Vienna, Austria) ;
Paez, Diana (Section of Nuclear Medicine and Diagnostic Imaging, Division of Human Health, International Atomic Energy Agency, Vienna, Austria) ;
Einstein, Andrew J. (Department of Radiology, Columbia University Medical Center and New York-Presbyterian Hospital, New York, NY USA) ;
Universitat Autònoma de Barcelona
Nuclear cardiology is widely used to diagnose coronary artery disease and to guide patient management, but data on current practices, radiation dose-related best practices, and radiation doses are scarce. [...]
2015 - 10.1007/s00259-015-3270-8
European Journal of Nuclear Medicine and Molecular Imaging, Vol. 43 (december 2015) , p. 718-728
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8 p, 197.0 KB |
Current worldwide nuclear cardiology practices and radiation exposure : results from the 65 country IAEA Nuclear Cardiology Protocols Cross-Sectional Study (INCAPS)
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Einstein, Andrew J. (Columbia University Medical Center and New York-Presbyterian Hospital) ;
Pascual, Thomas N. B. (International Atomic Energy Agency) ;
Mercuri, Mathew (Columbia University Medical Center and New York-Presbyterian Hospital) ;
Karthikeyan, Ganesan (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Vitola, João V. (Quanta Diagnóstico & Terapia) ;
Mahmarian, John J. (Department of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, TX) ;
Better, Nathan (Royal Melbourne Hospital (Melbourne, Austràlia)) ;
Bouyoucef, Salah E. (Centre Hospitalo-Universitaire de Bab El Ouéd) ;
Hee-Seung Bom, Henry (Chonnam National University Medical School) ;
Lele, Vikram (Jaslok Hospital and Research Centre) ;
Magboo, V. Peter C. (University of Santo Tomas Hospital) ;
Alexánderson, Erick (Instituto Nacional de Cardiología 'Ignacio Chávez') ;
Allam, Adel H. (Al Azhar University) ;
Al-Mallah, Mouaz H. (King Saud bin Abdulaziz University for Health Sciences) ;
Flotats, Albert (Institut d'Investigació Biomèdica Sant Pau) ;
Jerome, Scott (University of Maryland) ;
Kaufmann, Philipp A. (University Hospital Zurich (Suïssa)) ;
Luxenburg, Osnat (Gertner Institute for Epidemiology and Health Policy Research) ;
Shaw, Leslee J. (Emory University School of Medicine) ;
Underwood, S. Richard (Royal Brompton Hospital (Londres)) ;
Rehani, Madan M. (Radiation Protection of Patients Unit, International Atomic Energy Agency) ;
Kashyap, Ravi (International Atomic Energy Agency) ;
Paez, Diana (International Atomic Energy Agency) ;
Dondi, Maurizio (International Atomic Energy Agency) ;
Universitat Autònoma de Barcelona
To characterize patient radiation doses from nuclear myocardial perfusion imaging (MPI) and the use of radiation-optimizing 'best practices' worldwide, and to evaluate the relationship between laboratory use of best practices and patient radiation dose. [...]
2015 - 10.1093/eurheartj/ehv117
European heart journal, Vol. 36 (april 2015) , p. 1689-1696
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