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15 p, 757.7 KB |
Calcium Imaging In Electrically Stimulated Flat-Mounted Retinas
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Cunquero Navarro, Marina (Institut de Ciències Fotòniques) ;
Marsal, Maria (Institut de Ciències Fotòniques) ;
Castro-Olvera, Gustavo (Institut de Ciències Fotòniques) ;
Walston, Steven T. (Institut Català de Nanociència i Nanotecnologia) ;
Duvan, Fikret Taygun (Institut Català de Nanociència i Nanotecnologia) ;
Macias-Montero, José Gabriel (Institut de Física d'Altes Energies) ;
Puigdengoles, Carles (Institut de Física d'Altes Energies) ;
Chmeissani, Mokhtar (Institut de Física d'Altes Energies) ;
Garrido, Jose (Institut Català de Nanociència i Nanotecnologia) ;
Loza-Alvarez, Pablo (Institut de Ciències Fotòniques)
Retinal dystrophies are a leading cause of blindness worldwide. Extensive efforts are underway to develop advanced retinal prostheses that can bypass the impaired light-sensing photoreceptor cells in the degenerated retina, aiming to partially restore vision by inducing visual percepts. [...]
2023 -  10.3791/65705
Journal of visualized experiments, Núm. 198 (August 2023) , art. e65705
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2.
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5 p, 3.7 MB |
Decreased activation of parvalbumin interneurons in the medial prefrontal cortex in intact inbred Roman rats with schizophrenia-like reduced sensorimotor gating
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Tapias-Espinosa, Carles (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sánchez González, Ana (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Cañete, Toni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sampedro-Viana, Daniel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Castillo-Ruiz, Mª del Mar (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Tobeña, Adolf 1950- (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Oliveras, Ignasi ;
Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Aznar, Susana (Research Laboratory for Stereology and Neuroscience, Bispebjerg Copenhagen University Hospital)
Prepulse inhibition (PPI) allows assessing schizophrenia-like sensorimotor gating deficits in rodents. Previous studies indicate that PPI is modulated by the medial prefrontal cortex (mPFC), which is in agreement with our findings showing that PPI differences in the Roman rats are associated with divergences in mPFC activity. [...]
2023 - 10.1016/j.bbr.2022.114113
Behavioural Brain Research, Vol. 437 (Feb. 2023) , art. 114113
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104 p, 1.6 MB |
Neurobehavioral and neurodevelopmental profiles of a heuristic genetic model of differential schizophrenia- and addiction-relevant features: The RHA vs. RLA rats
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Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Oliveras, Ignasi (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Cañete, Toni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Rio-Álamos, Cristóbal (Universidad Austral de Chile. Departamento de Psicologia) ;
Tapias-Espinosa, Carles (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sampedro-Viana, Daniel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sánchez-González, Ana (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sanna, Francesco (Universitá di Cagliari. Dipartimento di Scienze della vita e dell'ambiente) ;
Torrúbia, Rafael (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
González-Maeso, Javier (Virginia Commonwealth University School of Medicine. Department of Physiology and Biophysics) ;
Driscoll, Peter ;
Morón, Ignacio (Universidad de Granada. Departamento de Psicobiologia) ;
Torres, Carmen (Universidad de Jaén. Departamento de Psicología) ;
Aznar, Susana (Bispebjerg Copenhagen University Hospital) ;
Tobeña, Adolf 1950- (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corda, Maria G. (Universitá di Cagliari. Dipartimento di Scienze della vita e dell'ambiente) ;
Giorgi, Osvaldo (Universitá di Cagliari. Dipartimento di Scienze della vita e dell'ambiente) ;
Universitat Autònoma de Barcelona.
Institut de Neurociències
The Roman High- (RHA) and Low-(RLA) avoidance rat lines/strains were generated through bidirectional selective breeding for rapid (RHA) vs. extremely poor (RLA) two-way active avoidance acquisition. [...]
2021 - 10.1016/j.neubiorev.2021.09.042
Neuroscience and Biobehavioral Reviews, Vol. 131 (2021) , p. 597-617
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30 p, 681.2 KB |
Increased exploratory activity in rats with deficient sensorimotor gating: a study of schizophrenia-relevant symptoms with genetically heterogeneous NIH-HS and Roman rat strains
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Tapias-Espinosa, Carles (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Río-Álamos, Cristobal (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sampedro-Viana, Daniel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Gerbolés, Cristina (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Oliveras, Ignasi (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sánchez González, Ana (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Tobeña, Adolf 1950- (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Universitat Autònoma de Barcelona.
Institut de Neurociències
Schizophrenia involves positive, negative and cognitive symptoms, as well as comorbidity with anxiety and obsessive-compulsive disorder. Prepulse inhibition (PPI) of the startle response is a measure of sensorimotor gating that is impaired in schizophrenia and animal models of the disease. [...]
2018 - 10.1016/j.beproc.2018.03.019
Behavioural Processes, Vol. 151 (june 2018) , p. 96-103
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23 p, 5.8 MB |
Effects of Tail Pinch on BDNF and trkB Expression in the Hippocampus of Roman Low- (RLA) and High-Avoidance (RHA) Rats
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Serra, Maria Pina (University of Cagliari) ;
Sanna, Francesco (University of Cagliari) ;
Boi, Marianna (University of Cagliari) ;
Trucas, Marcello (University of Cagliari) ;
Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corda, Maria Giuseppa (University of Cagliari) ;
Giorgi, Osvaldo (University of Cagliari) ;
Quartu, Marina (University of Cagliari)
In this article, we describe the effects of tail pinch (TP), a mild acute stressor, on the levels of brain-derived neurotrophic factor (BDNF) and its tyrosine kinase receptor B (trkB) proteins in the hippocampus (HC) of the outbred Roman High- (RHA) and Low-Avoidance (RLA) rats, one of the most validated genetic models for the study of fear/anxiety- and stress-related behaviors. [...]
2023 - 10.3390/ijms24119498
International journal of molecular sciences, Vol. 24 (may 2023)
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7.
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19 p, 4.8 MB |
Intrapallidal injection of cannabidiol or a selective GPR55 antagonist decreases motor asymmetry and improves fine motor skills in hemiparkinsonian rats
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Patricio, Felipe (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ;
Morales Dávila, Eliud (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ;
Patricio-Martínez, Aleidy (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ;
Arana Del Carmen, Nayeli (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ;
Martínez, Isabel (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ;
Aguilera, José (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Perez-Aguilar, Jose Manuel (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ;
Limón, Ilhuicamina Daniel (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic))
Cannabidiol (CBD) presents antiparkinsonian properties and neuromodulatory effects, possibly due to the pleiotropic activity caused at multiple molecular targets. Recently, the GPR55 receptor has emerged as a molecular target of CBD. [...]
2022 - 10.3389/fphar.2022.945836
Frontiers in Pharmacology, Vol. 13 (september 2022)
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23 p, 6.2 MB |
Acute Stress Induces Different Changes on the Expression of BDNF and trkB in the Mesocorticolimbic System of Two Lines of Rats Differing in Their Response to Stressors
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Serra, Maria Pina (University of Cagliari) ;
Sanna, Francesco (University of Cagliari) ;
Boi, Marianna (University of Cagliari) ;
Poddighe, Laura (University of Cagliari) ;
Secci, Lorenzo (University of Cagliari) ;
Trucas, Marcello (University of Cagliari) ;
Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corda, Maria Giuseppa (University of Cagliari) ;
Giorgi, Osvaldo (University of Cagliari) ;
Quartu, Marina (University of Cagliari)
The present work was undertaken to investigate the effects of acute forced swimming (FS) on the levels of brain-derived neurotrophic factor (BDNF) and tyrosine kinase receptor B (trkB) proteins in: the ventral tegmental area (VTA); the nucleus accumbens (Acb) shell and core compartments; and the anterior cingulate (ACg), prelimbic (PL) and infralimbic (IL) territories of the prefrontal cortex of genetic models of vulnerability (RLA, Roman low-avoidance rats) and resistance (RHA, Roman high-avoidance rats) to stress-induced depression. [...]
2022 - 10.3390/ijms232314995
International journal of molecular sciences, Vol. 23 (november 2022)
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9.
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16 p, 4.5 MB |
Effects of Caloric Restriction on Spatial Object Recognition Memory, Hippocampal Neuron Loss and Neuroinflammation in Aged Rats
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Portero Tresserra, Marta (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Galofré-López, Neus (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Pallares, Elisabet (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Gimenez-Montes, Claudia (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Barcia, Carlos (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Granero, Roser (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Rojic-Becker, Divka (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Vale Martínez, Anna (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Martí Nicolovius, Margarita (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Guillazo i Blanch, Gemma (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Universitat Autònoma de Barcelona.
Institut de Neurociències
Age-related neurobiological changes significantly affect hippocampal structure and function, such that the main cognitive impairments associated with aging are related to the integrity of this brain structure, including the deterioration in spatial object recognition (SOR) memory. [...]
2023 - 10.3390/nu15071572
Nutrients, Vol. 15 Núm. 7 (2023) , art. 1572
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6 p, 674.5 KB |
ICLAS LAQ Network for the Promotion of Animal Quality in Research
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Vergara, Patri (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Ballard, Gregory (The Jackson Laboratory) ;
Besch-Williford, Cynthia (IDEXX BioAnalytics) ;
Hayashimoto, Nobuhito (Central Institute for Experimental Animals) ;
Pekow, Cynthia (University of Washington) ;
Perez, Ana (Humodigen) ;
Schmidt, Katja (German Cancer Research Center) ;
Shek, William (Charles River Laboratories) ;
Toft, Martin (Radboud University. QM Diagnostics) ;
Yoshiki, Atsushi (RIKEN BioResource Research Center)
ICLAS Laboratory Animal Quality Network (LAQN) programs currently consist of the Performance Evaluation Program (PEP), which focuses on microbial monitoring by and for laboratory animal diagnostic laboratories, and the Genetic Reference Monitoring Program (GENRef), which provides assay-ready reference DNA for genetic testing of mouse strains. [...]
2022 - 10.1093/ilar/ilac003
ILAR Journal, Vol. 62 (march 2022) , p. 337-342
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