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17 p, 921.2 KB |
Real-World Validation of Molecular International Prognostic Scoring System for Myelodysplastic Syndromes
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Sauta, Elisabetta (Humanitas Clinical and Research Center (Itàlia)) ;
Robin, Marie (Department of Hematology and Bone Marrow Transplantation. Hôpital Saint-Louis (França)) ;
Bersanelli, Mateo (Department of Biomedical Sciences. Humanitas University) ;
Travaglino, Erica (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Meggendorfer, Manje (Mll Munich Leukemia Laboratory) ;
Zhao, Lin-Pierre (Department of Hematology and Bone Marrow Transplantation. Hôpital Saint-Louis (França)) ;
Caballero Berrocal, Juan Carlos (Hematology Department. Hospital Universitario de Salamanca) ;
Sala, Claudia (Experimental. Diagnostic and Specialty Medicine. Dimes) ;
Maggioni, Giulia (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Bernardi, Massimo (University Vita-Salute San Raffaele (Itàlia)) ;
Di Grazia, Carmen (Irccs Ospedale Policlinico San Martino) ;
Vago, Luca (University Vita-Salute San Raffaele (Itàlia)) ;
Rivoli, Giulia (Irccs Ospedale Policlinico San Martino) ;
Borin, Lorenza (Ospedale San Gerardo) ;
D'Amico, Saverio (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Tentori, Cristina Astrid (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Ubezio, Marta (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Campagna, Alessia (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Russo, Antonio (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Mannina, Daniele (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Lanino, Luca (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Chiusolo, Patrizia (Università Cattolica Del Sacro Cuore) ;
Giaccone, Luisa (Department of Molecular Biotechnology and Health Sciences. University of Turin) ;
Voso, Maria Teresa (Tor Vergata University) ;
Riva, Maria (Asst Grande Ospedale Metropolitano Niguarda) ;
Oliva, Esther Natalie (Grande Ospedale Metropolitano Bianchi Melacrino Morelli) ;
Zampini, Matteo (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Riva, Elena (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Nibourel, Olivier (Chu Lille) ;
Bicchieri, Marinela (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Bolli, Niccolo (Department of Oncology and Hemato-Oncology. University of Milan) ;
Rambaldi, Alessandro (Azienda Ospedaliera Papa Giovanni Xxiii) ;
Passamonti, Francesco (Department of Medicine and Surgery. University of Insubria) ;
Savevski, Victor (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Santoro, Armando (Department of Biomedical Sciences. Humanitas University) ;
Germing, Ulrich (Department of Hematology. Heinrich-Heine-University. University Clinic) ;
Kordasti, Shahram (Hematology Department. DISCLIMO-Università Politecnica Delle Marche) ;
Santini, Valeria (University of Florence) ;
Diez-Campelo, María (Hospital Universitario de Salamanca) ;
Sanz, Guillermo (Hospital Universitari i Politècnic La Fe (València)) ;
Sole, F (Institut de Recerca Contra la Leucèmia Josep Carreras) ;
Kern, Wolfgang (Mll Munich Leukemia Laboratory) ;
Platzbecker, Uwe (University Hospital Leipzig) ;
Arenillas, Leonor (Department of Hematology and Bone Marrow Transplantation. Hôpital Saint-Louis) ;
Fenaux, Pierre (Department of Hematology and Bone Marrow Transplantation. Hôpital Saint-Louis) ;
Haferlach, Torsten (Mll Munich Leukemia Laboratory) ;
Castellani, Gastone (Experimental. Diagnostic and Specialty Medicine. Dimes) ;
Della Porta, Matteo Giovanni (Department of Biomedical Sciences. Humanitas University)
PURPOSEMyelodysplastic syndromes (MDS) are heterogeneous myeloid neoplasms in which a risk-adapted treatment strategy is needed. Recently, a new clinical-molecular prognostic model, the Molecular International Prognostic Scoring System (IPSS-M) was proposed to improve the prediction of clinical outcome of the currently available tool (Revised International Prognostic Scoring System [IPSS-R]). [...]
2023 -  10.1200/JCO.22.01784
Journal of Clinical Oncology, Vol. 41 Núm. 15 (20 2023) , p. 2827-2842
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11 p, 1.2 MB |
Clinical outcome and biomarker assessments of a multi-centre phase II trial assessing niraparib with or without dostarlimab in recurrent endometrial carcinoma
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Madariaga, Ainhoa (Universitat Autònoma de Barcelona) ;
Garg, Swati (University Health Network, Toronto, Canada) ;
Tchrakian, Nairi (University Health Network, Toronto, Canada) ;
Dhani, Neesha C. (University of Toronto, Canada) ;
Jimenez, Waldo (Juravinski Cancer Centre, Hamilton, Canada) ;
Welch, Stephen (London Health Sciences Center, London, Canada) ;
MacKay, Helen (Odette Cancer Centre. Sunnybrook Health Sciences Centre, Toronto, Canada) ;
Ethier, Josee-Lyne (Kingston Health Sciences Cancer Centre, Kingston, Canada) ;
Gilbert, Lucy (Royal Victoria Hospital, Montréal, Canada) ;
Li, Xuan (University Health Network, Toronto, Canada) ;
Rodriguez, Angela (University Health Network, Toronto, Canada) ;
Chan, Lucy (University Health Network, Toronto, Canada) ;
Bowering, Valerie (University Health Network, Toronto, Canada) ;
Clarke, Blaise (University Health Network, Toronto, Canada) ;
Zhang, Tong (University of Toronto, Canada) ;
King, Ian (University of Toronto, Canada) ;
Downs, Gregory (University of Toronto, Canada) ;
Stockley, Tracy (University of Toronto, Canada) ;
Wang, Lisa (University of Toronto, Toronto, Canada) ;
Udagani, Smitha (University Health Network, Toronto, Canada) ;
Oza, Amit M. (University of Toronto, Canada) ;
Lheureux, Stephanie (University of Toronto, Canada)
This multi-centre, non-randomized, open-label, phase II trial (NCT03016338), assessed niraparib monotherapy (cohort 1, C1), or niraparib and dostarlimab (cohort 2, C2) in patients with recurrent serous or endometrioid endometrial carcinoma. [...]
2023 - 10.1038/s41467-023-37084-w
Nature communications, Vol. 14 (2023) , art. 1452
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25 p, 1.7 MB |
Analysis of the Clinical Relevance of Histological Classification of Benign Epithelial Salivary Gland Tumours
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Hellquist, Henrik (University of Algarve) ;
Paiva-Correia, António (Manchester University NHS Foundation Trust) ;
Vander Poorten, Vincent (Multidisciplinary Salivary Gland Society) ;
Quer, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
Hernandez-Prera, Juan C. (Moffitt Cancer Center) ;
Andreasen, Simon (Zealand University Hospital) ;
Zbären, Peter (University Hospital) ;
Skalova, Alena (Charles University) ;
Rinaldo, Alessandra (University of Udine School of Medicine) ;
Ferlito, Alfio (International Head and Neck Scientific Group) ;
Universitat Autònoma de Barcelona
A vast increase in knowledge of numerous aspects of malignant salivary gland tumours has emerged during the last decade and, for several reasons, this has not been the case in benign epithelial salivary gland tumours. [...]
2019 - 10.1007/s12325-019-01007-3
Advances in Therapy, Vol. 36 Núm. 8 (january 2019) , p. 1950-1974
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15 p, 1.9 MB |
Can the Addition of Maintenance Electroconvulsive Therapy to Pharmacotherapy Improve Relapse Prevention in Severe Major Depressive Disorder? A Randomized Controlled Trial
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Martínez-Amorós, Erika (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Cardoner, N. (Narcís) (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Gálvez, Verònica (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
De Arriba-Arnau, Aida (Hospital Universitari de Bellvitge) ;
Soria, Virginia (Hospital Universitari de Bellvitge) ;
Palao, Diego Jose (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Menchón, José M. (Hospital Universitari de Bellvitge) ;
Urretavizcaya, Mikel (Hospital Universitari de Bellvitge)
Few systematic evaluations have been performed of the efficacy of electroconvulsive therapy (ECT) as a relapse prevention strategy in major depressive disorder (MDD). This is a single-blind, multicenter, randomized controlled trial to compare the efficacy and tolerability of pharmacotherapy plus maintenance ECT (M-Pharm/ECT) versus pharmacotherapy alone (M-Pharm) in the prevention of MDD relapse. [...]
2021 - 10.3390/brainsci11101340
Brain sciences, Vol. 11 (october 2021)
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12 p, 886.3 KB |
Lymphovascular Space Invasion in Early-Stage Endometrial Cancer (LySEC) : Patterns of Recurrence and Predictors. A Multicentre Retrospective Cohort Study of the Spain Gynecologic Oncology Group
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Oliver-Perez, M. Reyes (Hospital Universitario 12 de Octubre (Madrid)) ;
Padilla-Iserte, Pablo (Hospital Universitari i Politècnic La Fe (València)) ;
Arencibia-Sanchez, Octavio (Department of Gynecologic Oncology, University Hospital Materno-Infantil de Canarias) ;
Martin-Arriscado, Cristina (Hospital Universitario 12 de Octubre (Madrid)) ;
Muruzabal, Juan Carlos (Department of Gynecologic Oncology, Complejo Hospitalario de Navarra) ;
Díaz-Feijoo, Berta (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cabrera Díaz, Silvia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Coronado, Pluvio (Complutense University Madrid) ;
Martín-Salamanca, M. Belen (Department of Gynecology, Hospital Universitario de Getafe) ;
Pantoja-Garrido, Manuel (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Marcos-Sanmartin, Josefa (Institute for Health and Biomedical Research) ;
Cabezas-López, Elena (Department of Gynecologic Oncology, University Hospital Ramón y Cajal) ;
Lorenzo, Cristina (Department of Obstetrics and Gynecology, Hospital Nuestra Señora de la Calendaria) ;
Beric, Duska (Department of Obstetrics and Gynecology, Hospital Universitario de Torrevieja) ;
Rodriguez-Hernandez, Jose Ramon (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Roldan-Rivas, Fernando (Department of Obstetrics and Gynaecology, Clinico Lozano Blesa Hospita) ;
Gilabert-Estelles, Juan (Department of Pediatrics, Obstetrics and Gynecology, University General Hospital of Valencia) ;
Sanchez, Lourdes (Department of Gynecology and Obstetrics, University General Hospital of Ciudad Real) ;
Laseca-Modrego, Maria (Department of Gynecologic Oncology, University Hospital Materno-Infantil de Canarias) ;
Tauste-Rubio, Carmen (Department of Gynecologic Oncology, Complejo Hospitalario de Navarra) ;
Gil-Ibañez, Blanca (Hospital Universitario 12 de Octubre (Madrid)) ;
Tejerizo-Garcia, Alvaro (Hospital Universitario 12 de Octubre (Madrid)) ;
Universitat Autònoma de Barcelona
In patients with early-stage endometrioid endometrial cancer, the presence of lymph vascular space involvement (LVSI) correlates with nodal metastases, shorter disease-free survival and overall survival. [...]
2023 - 10.3390/cancers15092612
Cancers, Vol. 15 (may 2023)
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9 p, 203.7 KB |
Outcomes of men with HIV and germ cell cancer : Results from an international collaborative study
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Hentrich, Marcus Ulrich (Department of Hematology and Oncology. Red Cross Hospital. University of Munich) ;
Bower, Mark (National Centre for HIV Malignancy. Chelsea and Westminster Hospital) ;
Daugaard, Gedske (Department of Oncology. University Hospital Copenhagen. Rigshospitalet) ;
Dieing, Annette (Department of Hematology and Oncology. Vivantes Klinikum am Urban) ;
Bickel, Markus (Infektiologikum) ;
Berretta, Massimiliano (Department of Clinical and Experimental Medicine. University of Messina) ;
Lesmeister, Florian (Department of Hematology and Oncology. Red Cross Hospital. University of Munich) ;
Jurinovic, Vindi (Institute of Biometrics and Epidemiology. Ludwig Maximilian University of Munich) ;
Stoehr, Albrecht (Institute for Interdisciplinary Medicine) ;
Heinzelbecker, Julia (Department of Urology and Pediatric Urology. Saarland University Medical Center and Saarland University) ;
Krznaric, Ivanka (Practice of Infectious Diseases) ;
Dieckmann, Klaus-Peter (Department of Urology. Asklepios Klinik Altona) ;
Necchi, Andrea (IRCCS San Raffaele Hospital and Scientific Institute. Vita-Salute San Raffaele University) ;
Maroto Rey, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
Rockstroh, Jürgen Kurt (Department of Medicine I. University Hospital Bonn) ;
Brito, Margarida (Instituto Português de Oncologia Francisco Gentil) ;
Pfister, David (Department of Urology. University Hospital Cologne) ;
Hoffmann, Christian (University Hospital of Schleswig Holstein)
Background: Previous studies have shown that men with HIV and germ cell cancer (HIV-GCC) have inferior overall survival (OS) in comparison with their HIV-negative counterparts. However, little information is available on treatments and outcomes of HIV-GCC in the era of combination antiretroviral therapy (cART). [...]
2022 - 10.1002/cncr.33928
Cancer, Vol. 128 Núm. 2 (January 2022) , p. 260-268
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19 p, 1.1 MB |
Predicting Recurrence and Progression in Patients with Non-Muscle-Invasive Bladder Cancer : Systematic Review on the Performance of Risk Stratification Models
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Guerrero-Ramos, F. (Hospital Universitario 12 de Octubre (Madrid). Servicio de Urología) ;
Subiela, J.D. (Hospital Ramón y Cajal. Servicio de Urología. Instituto Ramón y Cajal de Investigación Sanitaria. Universidad De Alcalá) ;
Rodríguez Faba, Óscar (Institut d'Investigació Biomèdica Sant Pau) ;
Aumatell, Julia (Fundació Puigvert. Servicio de Urología) ;
Manfredi, Celeste (Unit Of Urology. Department Of Woman. Child And General And Specialized Surgery. University Of Campania 'Luigi Vanvitelli') ;
Bozzini, Giorgia (Department Of Urology. Asst Lariana Ospedale Sant'Anna) ;
Romero-Otero, Javier (Department Of Urology. Hospital Universitario Hm Sanchinarro) ;
Couñago, Felipe (Hospital La Milagrosa)
BACKGROUND: Several classifications have been reported to stratify non-muscle-invasive bladder cancer (NMIBC) in risk groups according to the probability of recurrence and progression. OBJECTIVE: To systematically review the current evidence regarding risk stratification of NMIBC. [...]
2022 - 10.3233/BLC-220055
Bladder Cancer, Vol. 8 Núm. 4 (2022) , p. 339-357
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19 p, 698.9 KB |
Fully resorbable poly-4-hydroxybutyrate (P4HB) mesh for soft tissue repair and reconstruction : A scoping review
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Deeken, Corey R. (Covalent Bio, LLC) ;
Chen, David C. (David Geffen School of Medicine at University of California) ;
López Cano, Manuel (Hospital Universitari Vall d'Hebron) ;
Martin, David P. (Becton, Dickinson and Company) ;
Badhwar, Amit (Becton, Dickinson and Company) ;
Universitat Autònoma de Barcelona
Poly-4-hydroxybutyrate (P4HB) is a fully resorbable, biologically-produced polymer with a strength and flexibility comparable to permanent synthetic polymers. The objective was to identify/summarize all peer-reviewed publications involving P4HB mesh. [...]
2023 - 10.3389/fsurg.2023.1157661
Frontiers in Surgery, Vol. 10 (april 2023)
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