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34 p, 1.3 MB |
Inhibitors of aldehyde dehydrogenases of the 1A subfamily as putative anticancer agents : Kinetic characterization and effect on human cancer cells
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Jiménez, Rafael (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Pequerul, Raquel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Amor Minguez, Adrián (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Lorenzo Rivera, Julia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Metwally, Kamel (Zagazig University. Department of Medicinal Chemistry) ;
Avilés, Francesc X (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Parés i Casasampera, Xavier (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Farrés, Jaume (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Aldehyde dehydrogenases (ALDHs) are enzymes catalyzing the NAD(P)+-dependent oxidation of aldehydes to their corresponding carboxylic acids. High ALDH activity has been related to some important features of cancer stem cells. [...]
2019 -  10.1016/j.cbi.2019.04.004
Chemico-Biological Interactions, Vol. 306 (2019) , p. 123-130
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11 p, 783.1 KB |
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay
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Shi, Liu (University of Oxford) ;
Westwood, Sarah (University of Oxford) ;
Baird, Alison L. (University of Oxford) ;
Winchester, Laura (University of Oxford) ;
Dobricic, Valerija (University of Lübeck) ;
Kilpert, Fabian (University of Lübeck) ;
Hong, Shengjun (University of Lübeck) ;
Franke, Andre (Christian-Albrechts-University of Kiel) ;
Hye, Abdul (King's College London) ;
Ashton, Nicholas J. (South London and Maudsley NHS Foundation) ;
Morgan, Angharad R. (Cardiff University) ;
Bos, Isabelle (Maastricht University) ;
Vos, Stephanie J.B. (Amsterdam UMC. University Medical Center) ;
Buckley, Noel J (University of Oxford) ;
Kate, Mara ten (Amsterdam UMC. University Medical Center) ;
Scheltens, Philip (Amsterdam UMC. University Medical Center) ;
Vandenberghe, Rik (University Hospitals Leuven (Bèlgica)) ;
Gabel, Silvy (Laboratory for Cognitive Neurology) ;
Meersmans, Karen (Laboratory for Cognitive Neurology) ;
Engelborghs, Sebastiaan (VUB University Hospital Brussels (UZ Brussel)) ;
De Roeck, Ellen E. (Institute Born-Bunge. University of Antwerp) ;
Sleegers, Kristel (Center for Molecular Neurology. VIB) ;
Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Blin, Olivier (Aix-Marseille Université) ;
Richardson, Jill C. (GlaxoSmithKline R&D) ;
Bordet, Régis (University of Lille) ;
Molinuevo, José Luis (Hospital Clínic i Provincial de Barcelona) ;
Rami, Lorena (Universitat Pompeu Fabra) ;
Wallin, Anders (Sahlgrenska Academy at University of Gothenburg) ;
Kettunen, Petronella (University of Oxford) ;
Tsolaki, Magda (AHEPA University Hospital (Grècia)) ;
Verhey, Frans (Maastricht University) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Popp, Julius (Geneva University Hospitals) ;
Peyratout, Gwendoline (Lausanne University Hospital) ;
Martinez-Lage, Pablo (Fundación CITA-Alzhéimer Fundazioa) ;
Tainta, Mikel (CITA-Alzheimer Foundation) ;
Johannsen, Peter Copenhagen University Hospital ;
Teunissen, Charlotte E. (Vrije Universiteit Amsterdam) ;
Freund-Levi, Yvonne (King's College London) ;
Frölich, Lutz (University of Heidelberg) ;
Legido-Quigley, Cristina (Steno Diabetes Center) ;
Barkhof, Frederik (UCL Institutes of Neurology and Healthcare Engineering) ;
Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ;
Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ;
Baker, Susan (Janssen R&D) ;
Morgan, B.Paul (Cardiff University) ;
Streffer, Johannes (Janssen R&D. LLC) ;
Visser, Pieter Jelle (Karolinska Institutet (Estocolm, Suècia)) ;
Bertram, Lars (University of Oslo) ;
Lovestone, Simon (University of Oxford) ;
Nevado-Holgado, Alejo (University of Oxford) ;
Universitat Autònoma de Barcelona
Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer's disease. [...]
2019 - 10.1016/j.jalz.2019.06.4951
Alzheimer's & Dementia, Vol. 15 Núm. 11 (november 2019) , p. 1478-1488
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8 p, 174.7 KB |
In Good Company? Personal Relationships, Network Embeddedness, and Social Inclusion
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Lubbers, Miranda J. (Universitat Autònoma de Barcelona. Departament d'Antropologia Social i Cultural)
How do individuals' networks of personal relationships affect their social in- and exclusion? Researchers have shown that micro-level, informal relationships can be highly consequential for social inclusion, but in complex, contradictory ways: Personal networks reflect the degree of relational exclusion and protect against (other forms of) exclusion, but they also erode in conditions of exclusion and reproduce exclusion. [...]
2021 - 10.17645/si.v9i4.5049
Social Inclusion, Vol. 9 Núm. 4 (2021) , p. 203-210
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12 p, 2.1 MB |
C, N, and P Stoichiometry Characteristics of Fresh and Weathered Sandstones in Longhushan Area, SE China
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Chang, Yunni (Fujian Normal University. College of Geographical Sciences) ;
Xu, Chaobin (Fujian Normal University. College of Geographical Sciences) ;
Qiu, Junting (Beijing Research Institute of Uranium Geology. National Key Laboratory of Science and Technology on Remote Sensing Information and Image Analysis) ;
Peñuelas, Josep (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Sardans i Galobart, Jordi (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Zeng, Hanzhao (Fujian Normal University. College of Geographical Sciences) ;
Zhong, Quanlin (Fujian Normal University. College of Geographical Sciences) ;
Li, Baoyin (Fujian Normal University. College of Geographical Sciences)
Carbon (C), nitrogen (N), and phosphorus (P) stoichiometry and their allometric relationships in soil and plants are hot topics that attract a lot of attention, while those rocks that form soils are often neglected. [...]
2023 - 10.3390/min13040483
Minerals, Vol. 13, Issue 4 (March 2023) , art. 483
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15 p, 1.2 MB |
A systematic review of the validated monogenic causes of human male infertility : 2020 update and a discussion of emerging gene-disease relationships
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Houston, Brendan J. (School of BioSciences and Bio21 Institute. The University of Melbourne) ;
Riera-Escamilla, Antoni (Institut d'Investigació Biomèdica Sant Pau) ;
Wyrwoll, Margot J. (Institute of Reproductive Genetics. University of Münster) ;
Salas-Huetos, Albert (Department of Nutrition. Harvard T.H. Chan School of Public Health. Harvard University) ;
Xavier, Miguel J. (Faculty of Medical Sciences. Biosciences Institute. Newcastle University) ;
Nagirnaja, Liina (Genetics of Male Infertility Initiative (GEMINI)) ;
Friedrich, Corinna (Institute of Reproductive Genetics. University of Münster) ;
Conrad, Donald F. (International Male Infertility Genomics Consortium (IMIGC)) ;
Aston, Kenneth I. (International Male Infertility Genomics Consortium (IMIGC)) ;
Krausz, Csilla (University of Florence) ;
Tüttelmann, Frank (International Male Infertility Genomics Consortium (IMIGC)) ;
O'bryan, Moira K. (International Male Infertility Genomics Consortium (IMIGC)) ;
Veltman, Joris A. (International Male Infertility Genomics Consortium (IMIGC)) ;
Oud, Manon S. (Department of Human Genetics. Donders Institute for Brain. Cognition and Behaviour. Radboudumc) ;
Universitat Autònoma de Barcelona
Background: Human male infertility has a notable genetic component, including well-established diagnoses such as Klinefelter syndrome, Y-chromosome microdeletions and monogenic causes. Approximately 4% of all infertile men are now diagnosed with a genetic cause, but a majority (60-70%) remain without a clear diagnosis and are classified as unexplained. [...]
2022 - 10.1093/humupd/dmab030
Human Reproduction Update, Vol. 28 Núm. 1 (january 2022) , p. 15-29
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17 p, 460.8 KB |
Evaluación de la combinación de clase invertida y uso de aplicaciones para promover una docencia universitaria interactiva
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Rodríguez-Pasquín, Myriam (University of Murcia) ;
Esteban-Yago, Miguel (University of Murcia) ;
López-Martínez, María (University of Murcia) ;
García-Luque, Olga (University of Murcia)
Este trabajo tiene como objetivo la evaluación de una propuesta docente que combina la clase invertida con el uso de aplicaciones en la asignatura Análisis del Entorno Económico, del grado de Relaciones Laborales y Recursos Humanos. [...]
Aquest treball té com a objectiu avaluar una proposta docent que combina la classe invertida amb l'ús d'aplicacions a l'assignatura Anàlisi de l'Entorn Econòmic, del grau de Relacions Laborals i Recursos Humans. [...]
Increasing the interaction between teachers and students and making university teaching more dynamic is an important objective, especially to increase students' desire to complete their courses. This paper presents the evaluation of an innovative initiative that combines a "flipped classroom" approach with the use of apps such as Wooclap, Socrative and Kahoot to promote interaction between teachers and students. [...]
2023 - 10.5565/rev/educar.1740
Educar, Vol. 59 Núm. 2 (2023) , p. 367-383 (Monográfico)
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28 p, 1.8 MB |
Farmer-buyer relationships and sustainable agricultural practices in the food supply chain : The case of vegetables in Chile
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Benitez-Altuna, Francisco Javier (Wageningen University and Research. Department of Social Science) ;
Materia, Valentina C. (Wageningen University and Research. Department of Social Science) ;
Bijman, Jos (Wageningen University and Research. Department of Social Science) ;
Gaitán-Cremaschi, Daniel (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ;
Trienekens, Jacques (Wageningen University and Research. Department of Social Science)
This study investigates how the relationship between farmers and buyers affects the adoption of sustainable agricultural practices (SAPs) in the vegetable sector in Chile. Specifically, we focus on the dyadic relationships between farmers and different types of buyers, including besides lead firms, intermediaries, and wholesalers, which have received little attention in the scientific literature. [...]
2023 - 10.1002/agr.21829
Agribusiness, (2023)
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22 p, 292.6 KB |
Invasiones vegetales : lo ecofantástico en tres relatos de autoras argentinas contemporáneas
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Barberán Abad, Sara (Universidad de Zaragoza)
No cabe ya duda de que lo fantástico, lejos de ser una literatura escapista, puede servirse de sus propios motivos y mecanismos como género a la hora de abordar problemáticas que afectan a las sociedades contemporáneas. [...]
Nowadays there is a consensus about the outstanding capacity of the fantastic genre to make use of its own motifs and mechanisms to address contemporary social issues. This is the case of three short stories written by contemporary Argentinean authors: «La mancha» (2017), by Patricia Ratto, «Miedo al sauce» (2019), by Gabriela Colombo and «Septiembre en la piel» (2019), by Yanina Rosenberg. [...]
2023 - 10.5565/rev/brumal.964
Brumal, Vol. 11 Núm. 1 (2023) , p. 145-166 (Monográfico)
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