Resultats globals: 19 registres trobats en 0.01 segons.
Articles, 17 registres trobats
Documents de recerca, 2 registres trobats
Articles 17 registres trobats  1 - 10següent  anar al registre:
1.
18 p, 4.8 MB Citric Acid Cycle Metabolites Predict Infarct Size in Pigs Submitted to Transient Coronary Artery Occlusion and Treated with Succinate Dehydrogenase Inhibitors or Remote Ischemic Perconditioning / Consegal, Marta (Universitat Autònoma de Barcelona. Departament de Medicina) ; Núñez, Norberto (Universitat Autònoma de Barcelona. Departament de Medicina) ; Barba, Ignasi (Universitat Autònoma de Barcelona. Departament de Medicina) ; Benito, Begoña (Universitat Autònoma de Barcelona. Departament de Medicina) ; Ruiz Meana, Marisol (Universitat Autònoma de Barcelona. Departament de Medicina) ; Inserte, Javier (Universitat Autònoma de Barcelona. Departament de Medicina) ; Ferreira-González, Ignacio (Universitat Autònoma de Barcelona. Departament de Medicina) ; Rodríguez-Sinovas, Antonio (Universitat Autònoma de Barcelona. Departament de Medicina)
Succinate dehydrogenase (SDH) inhibition with malonate during reperfusion reduced myocardial infarction in animals, whereas its endogenous substrate, succinate, is detected in plasma from STEMI patients. [...]
2021 - 10.3390/ijms22084151
International journal of molecular sciences, Vol. 22 (april 2021)  
2.
24 p, 1.4 MB Ischaemic conditioning and targeting reperfusion injury : a 30 year voyage of discovery / Hausenloy, Derek J. (National Heart Research Institute Singapore) ; Barrabés, José A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bøtker, Hans Erik (Aarhus University Hospital (Aarhus, Dinamarca)) ; Davidson, Sean M. (University College London) ; Di Lisa, Fabio (University of Padova, Italy) ; Downey, James (University of South Alabama, Mobile) ; Engstrom, Thomas (Copenhagen University Hospital) ; Ferdinandy, Péter (Pharmahungary Group, Szeged, Hungary) ; Carbrera-Fuentes, Hector A. (Kazan Federal University, Russian Federation) ; Heusch, Gerd (University of Essen Medical School, Germany) ; Ibanez, Borja (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ; Iliodromitis, Efstathios K. (National and Kapodistrian University of Athens, Greece) ; Inserte, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Jennings, Robert (Duke University, Durham, NC USA) ; Kalia, Neena (University of Birmingham, UK) ; Kharbanda, Rajesh (Oxford University Hospitals, UK) ; Lecour, Sandrine (University of Cape Town, South Africa) ; Marber, Michael (St. Thomas' Hospital, London, UK) ; Miura, Tetsuji (Sapporo Medical University School of Medicine, Japan) ; Ovize, Michel (Université Claude Bernard, Lyon 1, France) ; Perez-Pinzon, Miguel A. (University of Miami Miller School of Medicine, USA) ; Piper, Hans Michael (Carl von Ossietzky Universität Oldenburg) ; Przyklenk, Karin (Wayne State University, Detroit, USA) ; Schmidt, Michael Rahbek (Duke-National University of Singapore) ; Redington, Andrew (Cincinnati Children's Hospital Medical Center) ; Ruiz-Meana, Marisol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vilahur, Gemma (Institut d'Investigació Biomèdica Sant Pau) ; Vinten-Johansen, Jakob (Emory University, Atlanta, USA) ; Yellon, Derek M. (The National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, UK) ; García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
To commemorate the auspicious occasion of the 30th anniversary of IPC, leading pioneers in the field of cardioprotection gathered in Barcelona in May 2016 to review and discuss the history of IPC, its evolution to IPost and RIC, myocardial reperfusion injury as a therapeutic target, and future targets and strategies for cardioprotection. [...]
2016 - 10.1007/s00395-016-0588-8
Basic Research in Cardiology, Vol. 111 (october 2016)  
3.
14 p, 1.6 MB Implications of Iron Deficiency in STEMI Patients and in a Murine Model of Myocardial Infarction / Inserte, Javier (Universitat Autònoma de Barcelona) ; Barrabés, José A. (Universitat Autònoma de Barcelona) ; Aluja, David (Universitat Autònoma de Barcelona) ; Otaegui, Imanol (Universitat Autònoma de Barcelona) ; Bañeras, Jordi (Universitat Autònoma de Barcelona) ; Castellote, Laura (Hospital Universitari Vall d'Hebron) ; Sánchez, Ana (Universitat Autònoma de Barcelona) ; Rodríguez-Palomares, José F. (Universitat Autònoma de Barcelona) ; Pineda, Víctor (Institut de Diagnòstic per la Imatge, Barcelona, Spain) ; Miró-Casas, Elisabet (Universitat Autònoma de Barcelona) ; Milà, Laia (Universitat Autònoma de Barcelona) ; Lidón, Rosa-Maria (Universitat Autònoma de Barcelona) ; Sambola, Antonia (Universitat Autònoma de Barcelona) ; Valente, Filipa (Universitat Autònoma de Barcelona) ; Rafecas, Agnès (Universitat Autònoma de Barcelona) ; Ruiz-Meana, Marisol (Universitat Autònoma de Barcelona) ; Rodríguez-Sinovas, Antonio (Universitat Autònoma de Barcelona) ; Benito, Begoña (Universitat Autònoma de Barcelona) ; Buera, Irene (Universitat Autònoma de Barcelona) ; Delgado-Tomás, Sara (Universitat Autònoma de Barcelona) ; Beneitez Pastor, David (Vall d'Hebron Institut d'Oncologia) ; Ferreira-Gonzalez, Ignacio (Universitat Autònoma de Barcelona)
In patients with a first anterior ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention, iron deficiency (ID) was associated with larger infarcts, more extensive microvascular obstruction, and higher frequency of adverse left ventricular remodeling as assessed by cardiac magnetic resonance imaging. [...]
2021 - 10.1016/j.jacbts.2021.05.004
JACC: Basic to Translational Science, Vol. 6 (july 2021) , p. 567-580  
4.
10 p, 2.0 MB Connexin 43 deficiency is associated with reduced myocardial scar size and attenuated tgfβ1 signaling after transient coronary occlusion in conditional knock-out mice / Valls-Lacalle, Laura (Universitat Autònoma de Barcelona. Departament de Medicina) ; Consegal, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ruiz-Meana, Marisol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Benito, Begoña (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Inserte, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Barba, Ignasi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ferreira-Gonzalez, Ignacio (Universitat Autònoma de Barcelona. Departament de Medicina) ; Rodríguez-Sinovas, Antonio (Universitat Autònoma de Barcelona. Departament de Medicina)
Previous studies demonstrated a reduction in myocardial scar size in heterozygous Cx43-mice subjected to permanent coronary occlusion. However, patients presenting with ST segment elevation myocardial infarction often undergo rapid coronary revascularization leading to prompt restoration of coronary flow. [...]
2020 - 10.3390/biom10040651
Biomolecules, Vol. 10 Núm. 4 (april 2020) , p. 651  
5.
8 p, 623.6 KB In-hospital prognosis and long-term mortality of STEMI in a reperfusion network. "Head to head" analisys : invasive reperfusion vs optimal medical therapy / Garcia Garcia, Cosme (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ribas, Núria (Hospital del Mar (Barcelona, Catalunya)) ; Recasens, Lluís (Hospital del Mar (Barcelona, Catalunya)) ; Meroño, Oona (Hospital del Mar (Barcelona, Catalunya)) ; Subirana, Isaac (Institut Hospital del Mar d'Investigacions Mèdiques) ; Fernández, A. (Hospital del Mar (Barcelona, Catalunya)) ; Pérez, A. (Hospital del Mar (Barcelona, Catalunya)) ; Miranda, F. (Hospital del Mar (Barcelona, Catalunya)) ; Tizón-Marcos, H. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Martí-Almor, Julio (Institut Hospital del Mar d'Investigacions Mèdiques) ; Bruguera, Jordi (Hospital del Mar (Barcelona, Catalunya)) ; Elosua, Roberto (Universitat Autònoma de Barcelona. Departament de Medicina)
ST Segment Elevation Acute myocardial infarction (STEMI) preferred treatment is culprit artery reperfusion with primary percutaneous coronary intervention (PPCI). We ought to analyze the benefit of early reperfusion vs. [...]
2017 - 10.1186/s12872-017-0574-6
BMC Cardiovascular disorders, Vol. 17 (may 2017)  
6.
12 p, 516.3 KB Mitochondrial and mitochondrial-independent pathways of myocardial cell death during ischaemia and reperfusion injury / Davidson, Sean (University College London) ; Adameová, Adriana (Comenius University Bratislava) ; Barile, Lucio (Università Svizzera Italiana) ; Cabrera-Fuentes, H.A. (Justus-Liebig-University) ; Lazou, A. (Aristotle University of Thessaloniki) ; Pagliaro, Pasquale (University of Turin) ; Stensløkken, Kåre-Olav (University of Oslo) ; García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Acute myocardial infarction causes lethal injury to cardiomyocytes during both ischaemia and reperfusion (IR). It is important to define the precise mechanisms by which they die in order to develop strategies to protect the heart from IR injury. [...]
2020 - 10.1111/jcmm.15127
Journal of Cellular and Molecular Medicine, Vol. 24 (march 2020) , p. 3795-3806  
7.
20 p, 1.7 MB Timing of Recanalization and Functional Recovery in Acute Ischemic Stroke / Tsivgoulis, Georgios (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ; Saqqur, Maher (Department of Neuroscience, Hamad General Hospital, Doha) ; Sharma, Vijay K. (Division of Neurology, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore) ; Brunser, Alejandro (Department of Emergency Medicine, Clinica Alemana of Santiago, University of Desarrollo, Santiago) ; Eggers, Jürgen (Department of Neurology, Sana Hospital Lubeck, Lübeck) ; Mikulik, Robert (Medical Faculty, Masaryk University, Brno) ; Katsanos, Aristeidis H. (Department of Neurology, University of Ioannina School of Medicine, Ioannina) ; Sergentanis, Theodore N. (Department of Hygiene, Epidemiology, and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens) ; Vadikolias, Konstantinos (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ; Perren, Fabienne (Geneva University Hospitals) ; Rubiera del Fueyo, Marta A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bavarsad Shahripour, Reza (Department of Neurology, University of Alabama at Birmingham, Birmingham, AL) ; Nguyen, Huy Thang (Department of Cerebrovascular Disease, 115 The People Hospital, Ho Chi Minh) ; Martínez-Sánchez, Patricia (Torrecardenas Hospital, University of Almeria School of Health Sciences, Almeria) ; Safouris, Apostolos (Stroke Unit, Department of Neurology, Brugmann University Hospital, Brussels) ; Heliopoulos, Ioannis (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ; Shuaib, Ashfaq (Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB) ; Derksen, Carol (Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB) ; Voumvourakis, Konstantinos (University General Hospital Attikon (Haidari, Grècia)) ; Psaltopoulou, Theodora (Department of Hygiene, Epidemiology, and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens) ; Alexandrov, Anne W. (Department of Neurology, University of Tennessee Health Science Center, Memphis, TN) ; Alexandrov, Andrei V. (Department of Neurology, University of Alabama at Birmingham, Birmingham, AL) ; Universitat Autònoma de Barcelona
Although onset-to-treatment time is associated with early clinical recovery in acute ischemic stroke (AIS) patients treated with intravenous tissue plasminogen activator (tPA), the effect of the timing of tPA-induced recanalization on functional outcomes remains debatable. [...]
2020 - 10.5853/jos.2019.01648
Journal of Stroke, Vol. 22 (january 2020) , p. 130-140  
8.
13 p, 498.1 KB Translational issues for mitoprotective agents as adjunct to reperfusion therapy in patients with ST-segment elevation myocardial infarction / Bøtker, Hans Erik (Aarhus University Hospital (Aarhus, Dinamarca)) ; Cabrera-Fuentes, H.A (Kazan (Volga Region) Federal University) ; Ruiz-Meana, Marisol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Heusch, Gerd (University of Essen) ; Ovize, Michel (Université de Lyon)
Pre-clinical studies have indicated that mitoprotective drugs may add cardioprotection beyond rapid revascularization, antiplatelet therapy and risk modification. We review the clinical efficacy of mitoprotective drugs that have progressed to clinical testing comprising cyclosporine A, KAI-9803, MTP131 and TRO 40303. [...]
2020 - 10.1111/jcmm.14953
Journal of Cellular and Molecular Medicine, Vol. 24 (january 2020) , p. 2717-2729  
9.
14 p, 2.3 MB Degradation of GRK2 and AKT is an early and detrimental event in myocardial ischemia/reperfusion / Penela, Petronila (CIBER de Enfermedades Cardiovasculares (CIBERCV)) ; Inserte, Javier (Universitat Autònoma de Barcelona) ; Ramos, Paula (Departamento de Biología Molecular. Centro de Biología Molecular "Severo Ochoa" (UAM-CSIC)) ; Rodriguez-Sinovas, Antonio (Universitat Autònoma de Barcelona) ; García-Dorado, David (Universitat Autònoma de Barcelona) ; Mayor, F. (CIBER de Enfermedades Cardiovasculares (CIBERCV))
Background: Identification of signaling pathways altered at early stages after cardiac ischemia/reperfusion (I/R) is crucial to develop timely therapies aimed at reducing I/R injury. The expression of G protein-coupled receptor kinase 2 (GRK2), a key signaling hub, is up-regulated in the long-term in patients and in experimental models of heart failure. [...]
2019 - 10.1016/j.ebiom.2019.09.019
EBioMedicine, Vol. 48 (october 2019) , p. 605-618  
10.
9 p, 733.9 KB Secondary prevention strategies after an acute ST-segment elevation myocardial infarction in the AMI code era : beyond myocardial mechanical reperfusion / Ribas, Núria (Hospital del Mar (Barcelona, Catalunya)) ; Garcia Garcia, Cosme (Hospital del Mar (Barcelona, Catalunya)) ; Meroño, Oona (Hospital del Mar (Barcelona, Catalunya)) ; Recasens, Lluís (Hospital del Mar (Barcelona, Catalunya)) ; Pérez-Fernández, Silvia (Institut Hospital del Mar d'Investigacions Mèdiques) ; Bazán, Víctor (Hospital del Mar (Barcelona, Catalunya)) ; Salvatella, Neus (Hospital del Mar (Barcelona, Catalunya)) ; Martí-Almor, Julio (Hospital del Mar (Barcelona, Catalunya)) ; Bruguera, Jordi (Hospital del Mar (Barcelona, Catalunya)) ; Elosua, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona
The AMI code is a regional network enhancing a rapid and widespread access to reperfusion therapy (giving priority to primary angioplasty) in patients with acute ST-segment elevation myocardial infarction (STEMI). [...]
2017 - 10.1186/s12872-017-0493-6
BMC Cardiovascular disorders, Vol. 17 (february 2017)  

Articles : 17 registres trobats   1 - 10següent  anar al registre:
Documents de recerca 2 registres trobats  
1.
124 p, 1.8 MB ST-elevation myocardial infarction : gaps in current knowledge / Tizon Marcos, Helena ; Marrugat, Jaume, , dir. ; Poirier, Paul, dir. ; Cladellas Capdevila, Mercè, dir.
Les malalties isquèmiques del cor són la causa principal de mortalitat al món i a Europa. El seu mecanisme etiopatogènic fonamental és l'aterosclerosi; la inestabilització d'una lesió aterosclerosa comporta, eventualment, una síndrome coronària aguda. [...]
Las enfermedades isquémicas del corazón son la principal causa de muerte en el mundo y en Europa. El fenómeno etiopatogénico fundamental en la cardiopatía isquémica es la aterosclerosis y la inestabilización de las lesiones aterosclerosas comporta, eventualmente, un síndrome coronario agudo. [...]
Ischemic heart disease (IHD) is the leading cause of deaths in the world. In Europe ischemic heart disease is also the leading cause of death in both women and men. The disruption of an atherosclerotic lesion is the most common etiopathogenic finding of this entity. [...]
Universitat Autònoma de Barcelona. Programa de Doctorat en Medicina.

2021  
2.
223 p, 9.5 MB Identification of time- and sex-dependent pathways involved in renal ischemia-reperfusion injury in a porcine model. Link to renal cancer / Nemours, Stéphane ; Meseguer Navarro, Anna, dir.
Les malalties renals es deriven de defectes congènits, lesions renals agudes (AKI) o malalties renals cròniques (CKD), entre altres causes. La lesió renal d'isquèmia /reperfusió (IRI), que es troba en moltes situacions clíniques, és una de les causes principals de l'AKI que causen lesions i mort de cèl·lules epitelials del túbul proximal (PTEC). [...]
Las enfermedades renales se derivan de defectos congénitos, lesiones renales agudas (AKI) o enfermedad renal crónica (CKD), entre otras causas. La lesión renal de isquemia / reperfusión (IRI), que se encuentra en muchas situaciones clínicas, es una de las causas principales de AKI que causan lesiones y muerte de células epiteliales del túbulo proximal (PTEC). [...]
Kidney diseases arise from congenital defects, acute kidney injury (AKI) or chronic kidney disease (CKD), among other causes. Renal ischemia/reperfusion injury (IRI), which is faced in many clinical situations, is a major cause of AKI leading to injury and death of proximal tubule epithelial cells (PTEC). [...]

2020  

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