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16 p, 2.3 MB |
Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer
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Palomeras, S. (Universitat de Girona. Departament de Ciències Mèdiques) ;
Diaz-Lagares, Á. (University Clinical Hospital of Santiago(CHUS/SERGAS)) ;
Viñas, G. (Girona Biomedical Research Institute (IDIBGI)) ;
Setien, F. (Hospital Universitari de Bellvitge) ;
Ferreira, H.J. (Hospital Universitari de Bellvitge) ;
Oliveras, G. (Pathology Department. Dr. Josep Trueta Hospital and Catalan Institute of Health (ICS)) ;
Crujeiras, A.B. (CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn)) ;
Hernández, A. (Institut Català d'Oncologia) ;
Lum, D.H. (University of Utah. Huntsman Cancer Institute) ;
Welm, A.L. (University of Utah. Huntsman Cancer Institute) ;
Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Puig, T. (Universitat de Girona. Departament de Ciències Mèdiques) ;
Universitat Autònoma de Barcelona
Background: Acquired resistance to trastuzumab is a major clinical problem in the treatment of HER2-positive (HER2+) breast cancer patients. The selection of trastuzumab-resistant patients is a great challenge of precision oncology. [...]
2019 - 10.1186/s13058-019-1160-x
Breast cancer research, Vol. 21 Núm. 1 (may 2019) , p. 79
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12 p, 2.0 MB |
Ultrasensitive label-free detection of unamplified multidrug-resistance bacteria genes with a bimodal waveguide interferometric biosensor
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Maldonado, Jesús (Institut Català de Nanociència i Nanotecnologia) ;
González-Guerrero, Ana Belén (Institut Català de Nanociència i Nanotecnologia) ;
Fernández Gavela, Adrián (Institut Català de Nanociència i Nanotecnologia) ;
González, Juan José (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia)
Infections by multidrug-resistant bacteria are becoming a major healthcare emergence with millions of reported cases every year and an increasing incidence of deaths. An advanced diagnostic platform able to directly detect and identify antimicrobial resistance in a faster way than conventional techniques could help in the adoption of early and accurate therapeutic interventions, limiting the actual negative impact on patient outcomes. [...]
2020 - 10.3390/diagnostics10100845
Diagnostics, Vol. 10, issue 10 (Oct. 2020) , art. 845
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33 p, 265.9 KB |
Does the experience of imprisonment affect optimism about reentry?
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Cid Moliné, Josep (Universitat Autònoma de Barcelona. Grup de Recerca en Desistiment del Delicte i Polítiques de Reinserció) ;
Pedrosa, Albert 1992- (Universitat Autònoma de Barcelona. Grup de Recerca en Desistiment del Delicte i Polítiques de Reinserció) ;
Ibàñez i Roig, Aina (Universitat Autònoma de Barcelona. Grup de Recerca en Desistiment del Delicte i Polítiques de Reinserció) ;
Martí Olivé, Joel (Universitat Autònoma de Barcelona. Centre d'Estudis Sociològics sobre la Vida Quotidiana i el Treball (QUIT))
Desistance research has linked prison inmate expectations with positive outcomes after release, but very little research addresses what makes them optimistic about their future. Using data from a representative sample, this article analyzes whether the manner in which a prison sentence is served impacts expectations about reentry. [...]
2020 - 10.1177/0032885520978476
The Prison Journal, Vol. 101 Núm. 1 (2020)
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12 p, 5.0 MB |
Phonon bridge effect in superlattices of thermoelectric tinisn/hfnisn with controlled interface intermixing
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Heinz, Sven (Johannes Gutenberg University. Institute of Physics) ;
Chávez Ángel, Emigdio (Institut Català de Nanociència i Nanotecnologia) ;
Trapp, Maximilian (Darmstadt University of Technology. Institute of Applied Geosciences) ;
Kleebe, Hans-Joachim (Institut Català de Nanociència i Nanotecnologia) ;
Jakob, Gerhard (Johannes Gutenberg Universität Mainz. Graduate School of Excellence Materials Science)
The implementation of thermal barriers in thermoelectric materials improves their power conversion rates effectively. For this purpose, material boundaries are utilized and manipulated to affect phonon transmissivity. [...]
2020 - 10.3390/nano10061239
Nanomaterials, Vol. 10, issue 6 (June 2020) , art. 1239
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5 p, 501.9 KB |
Escherichia coli O157:H7 in wild boars (Sus scrofa) and Iberian ibex (Capra pyrenaica) sharing pastures with free-ranging livestock in a natural environment in Spain
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Navarro-Gonzalez, Nora (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge) ;
Porrero, M. Concepción (Centro de Vigilancia Sanitaria Veterinaria (VISAVET)) ;
Mentaberre García, Gregorio (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge) ;
Serrano Ferron, Emmanuel (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge) ;
Mateos, Ana (Centro de Vigilancia Sanitaria Veterinaria (VISAVET)) ;
Cabal, Adriana (Centro de Vigilancia Sanitaria Veterinaria (VISAVET)) ;
Domínguez, Lucas (Centro de Vigilancia Sanitaria Veterinaria (VISAVET)) ;
Lavín González, Santiago (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
Wild ungulates have greatly increased in abundance and range throughout Europe. This new situation presents a concern for public health because many wild ungulates are known reservoirs of zoonotic pathogens. In this work, we tested for the presence of the zoonotic pathogen Escherichia coli O157:H7 in free-ranging livestock and sympatric wild boars (Sus scrofa) and Iberian ibex (Capra pyrenaica) in NE Spain from 2009 to 2011. [...]
2015 - 10.1080/01652176.2015.1023404
Veterinary Quarterly, Vol. 35 Núm. 2 (2015) , p. 102-106
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4 p, 871.1 KB |
Comment on: "The treatment of sarcoptic mange in wildlife: a systematic review"
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Moroni, Barbara (Universitá di Torino. Dipartimento di Scienze Veterinarie) ;
Valldeperes, Marta (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge) ;
Serrano Ferron, Emmanuel (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge) ;
López Olvera, Jorge R. (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge) ;
Lavín González, Santiago (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Rossi, Luca (Universitá di Torino. Dipartimento di Scienze Veterinarie)
This letter comments on the article "The treatment of sarcoptic mange in wildlife: a systematic review" published in Parasites & Vectors 2019, 12:99, and discusses the limitations in the use of endectocides for scabies control in free-ranging wildlife. [...]
2020 - 10.1186/s13071-020-04347-0
Parasites & vectors, Vol. 13 (Setembre 2020) , p. 471
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20 p, 4.5 MB |
TSPAN1 : a Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance
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Garcia Mayea, Yoelsis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mir, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Carballo, Laia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Castellvi, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Temprana-Salvador, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lorente, Juan (Hospital Universitari Vall d'Hebron) ;
Benavente, Sergi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
García-Pedrero, Juana M. (Centro de Investigación Biomédica en Red Cáncer (CIBERONC)) ;
Allonca, Eva (Centro de Investigación Biomédica en Red Cáncer (CIBERONC)) ;
Rodrigo, Juan P. (Centro de Investigación Biomédica en Red Cáncer (CIBERONC)) ;
LLeonart, Matilde E. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Sensitization of resistant cells and cancer stem cells (CSCs) represents a major challenge in cancer therapy. A proteomic study revealed tetraspanin-1 (TSPAN1) as a protein involved in acquisition of cisplatin (CDDP) resistance (Data are available via ProteomeXchange with identifier PXD020159). [...]
2020 - 10.3390/cancers12113269
Cancers, Vol. 12 Núm. 11 (2020) , p. 3269
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