Home > Search Results: Rupatadine
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Results overview: Found 3 records in 0.02 seconds.
Articles, 2 records found
Research literature, 1 records found
Articles 2 records found  
1.
8 p, 888.7 KB Rupatadine Oral Solution Titration by Body Weight in Paediatric Patients Suffering from Allergic Rhinitis : A Population Pharmacokinetic Study / Santamaria, Eva (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Izquierdo, Iñaki (Biorhom SL Grupo Uriach) ; Valle, Marta (Institut d'Investigació Biomèdica Sant Pau)
Allergic rhinitis (AR) and chronic urticaria, both are treated in children with doses of second generation of antihistamines that have been mostly based on extrapolation of data obtained in adults. The objectives of this work were to develop a model to explain the pharmacokinetics (PK) of rupatadine, a second generation antihistamine, administered to children 2−11 years old and to calculate the non-compartmental PK parameters for two groups of age (2-5 and 6-11 years old) based on the individual Bayesian estimates from the selected model. [...]
2021 - 10.2147/CPAA.S312911
Clinical Pharmacology : Advances and Applications, Vol. 13 (june 2021) , p. 115-122  
Detailed record - Creative Commons
2.
7 p, 879.9 KB Rupatadine oral solution for 2-5-year-old children with allergic rhinitis : a safety, open-label, prospective study / Santamaría Masdeu, Eva (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Izquierdo, Iñaki (R&D, J. Uriach y Compañía (Barcelona, Catalunya)) ; Valle, Marta (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Vermeulen, Jan (Allergic Department, Parow Research, Cape Town, South Africa) ; Potter, Paul (Allergy Diagnostic and Clinical Research Unit, Department of Medicine, University of Cape Town Lung Institute, Cape Town, South Africa)
There are few clinical trials that assess the efficacy of antihistamines in very young children. Rupatadine is a second-generation antihistamine indicated for the treatment of allergic rhinitis (AR) and urticaria. [...]
2018 - 10.2147/JAA.S164632
Journal of Asthma and Allergy, Vol. 11 (september 2018) , p. 225-231  
Detailed record - Creative Commons

Research literature 1 records found  
1.
276 p, 1.7 MB Evaluation of caridotoxicity of rupatadine, and antihistamine, as recommendeded by ICH E14 / Donado Budiño, Esther Guillermina ; Antonijoan Arbós, Rosa Ma., dir. (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia
OBJETIVOS: Para evaluar los efectos de las dosis terapéuticas y supraterapéuticas de rupatadina en la repolarización cardiaca mediante un 'thorough QT/QTc study', realizado de acuerdo con la Conferencia Internacional sobre las directrices de armonización. [...]
[Barcelona] : Universitat Autònoma de Barcelona, 2016  
Detailed record - Creative Commons

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