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Resultats globals: 3 registres trobats en 0.02 segons.
Articles, 3 registres trobats
Articles 3 registres trobats  
1.
10 p, 3.7 MB SAMHD1 expression modulates innate immune activation and correlates with ovarian cancer prognosis / Gutiérrez-Chamorro, Lucía (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Felip, Eudald (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bernat-Peguera, Adrià (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ezeonwumelu, I.J (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Teruel, Iris (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Clotet Sala, Bonaventura (Centro de Investigación Biomédica en Red de Enfermedades Infecciosas) ; Riveira-Muñoz, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Romeo, Margarita (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Margelí, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ballana, Ester (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
SAMHD1 is a deoxynucleotide triphosphate (dNTP) triphosphohydrolase which has been proposed as a putative prognostic factor in haematological cancers and certain solid tumours, although with controversial data. [...]
2023 - 10.3389/fimmu.2023.1112761
Frontiers in immunology, Vol. 14 (february 2023)  
Registre complet - Creative Commons
2.
20 p, 1.9 MB Modulation of DNA Damage Response by SAM and HD Domain Containing Deoxynucleoside Triphosphate Triphosphohydrolase (SAMHD1) Determines Prognosis and Treatment Efficacy in Different Solid Tumor Types / Felip, Eudald (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gutiérrez-Chamorro, Lucía (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Gómez, Maica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; García Vidal, Edurne (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Romeo, Margarita (Universitat Autònoma de Barcelona. Departament de Medicina) ; Morán, Teresa (Universitat Autònoma de Barcelona. Departament de Medicina) ; Layos, Laura (Universitat Autònoma de Barcelona. Departament de Medicina) ; Pérez-Roca, Laia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Riveira-Muñoz, Eva (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Fernández, Pedro Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mesía, Ricard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ballana, Ester (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Margelí, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Ample evidence exists connecting dNTP pool dysregulation to cancer and genomic instability. SAMHD1, the unique dNTP triphosphohydrolase described in humans, has been proposed to play a key role in hematological cancers, although its value in advanced solid tumors has not yet been explored. [...]
2022 - 10.20944/preprints202201.0141.v1
Cancers, Vol. 14 Núm. 3 (january 2022)  
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3.
25 p, 2.8 MB Detailed Characterization of Early HIV-1 Replication Dynamics in Primary Human Macrophages / Bejarano, David Alejandro (Department of Infectious Diseases, Virology. University of Heidelberg. Heidelberg, Germany) ; Puertas, Maria C.. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Börner, Kathleen (German Center for Infection Research, Partner Site Heidelberg. Heidelberg, Germany) ; Martinez-Picado, Javier (Institució Catalana de Recerca i Estudis Avançats) ; Müller, Barbara (Department of Infectious Diseases, Virology, University of Heidelberg. Heidelberg, Germany) ; Kräusslich, Hans-Georg (German Center for Infection Research, Partner Site Heidelberg. Heidelberg, Germany)
Macrophages are natural target cells of human immunodeficiency virus type 1 (HIV-1). Viral replication appears to be delayed in these cells compared to lymphocytes; however, little is known about the kinetics of early post-entry events. [...]
2018 - 10.3390/v10110620
Viruses, Vol. 10 (november 2018)  
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