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Resultats globals: 8 registres trobats en 0.01 segons.
Articles, 8 registres trobats
Articles 8 registres trobats  
1.
13 p, 1.5 MB Inspecting the Ribozyme Region of Hepatitis Delta Virus Genotype 1 : Conservation and Variability / Pacín Ruiz, Beatriz (Hospital Universitari Vall d'Hebron) ; Cortese, Maria Francesca (Hospital Universitari Vall d'Hebron) ; Tabernero, David (Hospital Universitari Vall d'Hebron) ; Sopena, Sara (Hospital Universitari Vall d'Hebron) ; Gregori i Font, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García-García, Selene (Hospital Universitari Vall d'Hebron) ; Casillas, Rosario (Hospital Universitari Vall d'Hebron) ; Najarro-Centeno, Adrián (Hospital Universitari Vall d'Hebron) ; Aldama, Unai (Hospital Universitari Vall d'Hebron) ; Palom, Adriana (Hospital Universitari Vall d'Hebron) ; Rando-Segura, Ariadna (Hospital Universitari Vall d'Hebron) ; Galán, Anna (Hospital Universitari Vall d'Hebron) ; Vila, Marta (Hospital Universitari Vall d'Hebron) ; Riveiro Barciela, Mar (Hospital Universitari Vall d'Hebron) ; Quer, Josep 1963- (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González-Aseguinolaza, Gloria (Univerdad de Pamplona) ; Buti, Maria (Hospital Universitari Vall d'Hebron) ; Rodríguez Frías, Francisco (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
The hepatitis delta virus (HDV) genome has an autocatalytic region called the ribozyme, which is essential for viral replication. The aim of this study was to use next-generation sequencing (NGS) to analyze the ribozyme quasispecies (QS) in order to study its evolution and identify highly conserved regions potentially suitable for a gene-silencing strategy. [...]
2022 - 10.3390/v14020215
Viruses, Vol. 14 (january 2022)  
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2.
10 p, 13.8 MB Argonaute 2 Controls Antiviral Activity against Sweet Potato Mild Mottle Virus in Nicotiana benthamiana / Kenesi, Erzsébet (Institute of Plant Biology) ; Lopez-Moya, Juan Jose (Centre de Recerca en Agrigenòmica) ; Orosz, László (University of Szeged. Department of Medical Microbiology and Immunobiology) ; Burgyán, József (Agricultural Biotechnology Institute) ; Lakatos, Lóránt (Institute of Plant Biology)
RNA silencing is a sequence specific post-transcriptional mechanism regulating important biological processes including antiviral defense in plants. Argonaute (AGO) proteins, the catalytic subunits of the silencing complexes, are loaded with small RNAs to execute the sequence specific RNA cleavage or translational inhibition. [...]
2021 - 10.3390/plants10050867
Plants, Vol. 10, Issue 5 (April 2021) , art. 867  
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3.
13 p, 2.4 MB The P1 Protein of Watermelon mosaic virus Compromises the Activity as RNA Silencing Suppressor of the P25 Protein of Cucurbit yellow stunting disorder virus / Domingo Calap, María Luisa (Centre de Recerca en Agrigenòmica) ; Chase, Ornela (Centre de Recerca en Agrigenòmica) ; Estapé, Mariona (Centre de Recerca en Agrigenòmica) ; Moreno, Ana Beatriz (Centre de Recerca en Agrigenòmica) ; Lopez-Moya, Juan Jose (Centre de Recerca en Agrigenòmica)
Mixed viral infections in plants involving a potyvirus and other unrelated virus often result in synergistic effects, with significant increases in accumulation of the non-potyvirus partner, as in the case of melon plants infected by the potyvirus Watermelon mosaic virus (WMV) and the crinivirus Cucurbit yellow stunting disorder virus (CYSDV). [...]
2021 - 10.3389/fmicb.2021.645530
Frontiers in microbiology, Vol. 12 (March 2021) , art. 645530  
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4.
12 p, 3.2 MB Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type / Karnezis, Anthony N. (University of British Columbia. Department of Pathology and Laboratory Medicine) ; Wang, Yemin (University of British Columbia. Department of Pathology and Laboratory Medicine) ; Ramos, Pilar (Translational Genomics Research Institute) ; Hendricks, William P. D. (Translational Genomics Research Institute) ; Oliva, Esther (Massachusetts General Hospital (Boston)) ; D'Angelo, Emanuela (Institut d'Investigació Biomèdica Sant Pau) ; Prat, Jaime (Institut d'Investigació Biomèdica Sant Pau) ; Nucci, Marisa R. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Nielsen, Torsten O. (University of British Columbia. Department of Pathology and Laboratory Medicine) ; Chow, Christine (University of British Columbia. Genetic Pathology Evaluation Centre) ; Leung, Samuel (University of British Columbia. Genetic Pathology Evaluation Centre) ; Kommoss, Friedrich (Synlab MVZ Pathologie) ; Kommoss, Stefan (University Hospital of Tübingen (Alemanya)) ; Silva, Annacarolina (Harvard Medical School. The James Homer Wright Pathology Laboratories) ; Ronnett, Brigitte M. (The Johns Hopkins Hospital. Department of Pathology) ; Rabban, Joseph T. (University of California San Francisco. Department of Anatomic Pathology) ; Bowtell, David D. (Peter MacCallum Cancer Centre) ; Weissman, Bernard E. (University of North Carolina. Department of Pathology and Laboratory Medicine) ; Trent, Jeffrey M. (Translational Genomics Research Institute) ; Gilks, C. Blake (University of British Columbia. Department of Pathology and Laboratory Medicine) ; Huntsman, David G. (University of British Columbia. Department of Pathology and Laboratory Medicine) ; Universitat Autònoma de Barcelona
Small cell carcinoma of the ovary, hypercalcaemic type () is a lethal and sometimes familial ovarian tumour of young women and children. We and others recently discovered that over 90% of harbour inactivating mutations in the chromatin remodelling gene with concomitant loss of its encoded protein (), one of two mutually exclusive of the / chromatin remodelling complex. [...]
2015 - 10.1002/path.4633
The Journal of Pathology, Vol. 238, Issue 3 (december 2015) , p. 389-400  
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5.
16 p, 2.1 MB Cationic liposome- multi-walled carbon nanotubes hybrids for dual siPLK1 and doxorubicin delivery in vitro / Pereira, Sara (University of East Anglia. School of Pharmacy) ; Lee, Jin (King's College London. Institute of Pharmaceutical Science) ; Rubio, Noelia (King's College London. Institute of Pharmaceutical Science) ; Hassan, Hatem A. F. M. (King's College London. Institute of Pharmaceutical Science) ; Suffian, Izzat Bin Mohamed (King's College London. Institute of Pharmaceutical Science) ; Wang, Julie T. W. (King's College London. Institute of Pharmaceutical Science) ; Klippstein, Rebecca (King's College London. Institute of Pharmaceutical Science) ; Ballesteros, Belén (Institut Català de Nanociència i Nanotecnologia) ; Al-Jamal, Wafa' T. (University of East Anglia. School of Pharmacy) ; Al-Jamal, Khuloud T. (King's College London. Institute of Pharmaceutical Science)
To formulate f -MWNTs-cationic liposome hybrids for the simultaneous delivery of siPLK1 and doxorubicin to cancer cells. f -MWNTs-cationic liposome hybrids were prepared by the thin film hydration method where the lipid film was hydrated with 100 μg/ml or 1 mg/ml of ox-MWNTs-NH₃+ or MWNTs-NH₃+ in 5% dextrose. [...]
2015 - 10.1007/s11095-015-1707-1
Pharmaceutical research, Vol. 32, Issue 10 (Oct. 2015) , p. 3293-3308  
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6.
42 p, 1.9 MB Impact of transposable elements on polyploid plant genomes / Vicient Sánchez, Carlos M. (Centre de Recerca en Agrigenòmica) ; Casacuberta i Suñer, Josep M. 1962- (Centre de Recerca en Agrigenòmica)
Background: the growing wealth of knowledge on whole-plant genome sequences is highlighting the key role of transposable elements (TEs) in plant evolution, as a driver of drastic changes in genome size and as a source of an important number of new coding and regulatory sequences. [...]
2017 - 10.1093/aob/mcx078
Annals of botany, Vol. 120, issue 2 (Aug. 2017) , p. 195-207  
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7.
54 p, 2.0 MB The HCPro from the Potyviridae family : an enviable multitasking Helper Component that every virus would like to have / Valli, Adrián A. (Centro Nacional de Biotecnología (Espanya)) ; Gallo, Araiz (Centro Nacional de Biotecnología (Espanya)) ; Rodamilans, Bernardo (Centro Nacional de Biotecnología (Espanya)) ; Lopez-Moya, Juan Jose (Centre de Recerca en Agrigenòmica) ; García, Juan Antonio (Centro Nacional de Biotecnología (Espanya))
RNA viruses have very compact genomes and so provide a unique opportunity to study how evolution works to optimize the use of very limited genomic information. A widespread viral strategy to solve this issue concerning the coding space relies on the expression of proteins with multiple functions. [...]
2018 - 10.1111/mpp.12553
Molecular plant pathology, Vol. 19, issue3 (March 2018) , p. 744-763  
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8.
20 p, 10.3 MB PKM2 subcellular localization is involved in oxaliplatin resistance acquisition in HT29 human colorectal cancer cell lines / Ginés Molina, Alba (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bystrup, Sara (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Guardia, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Musulén, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Manzano, José Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Layos, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Abad, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Chemoresistance is the main cause of treatment failure in advanced colorectal cancer (CRC). However, molecular mechanisms underlying this phenomenon remain to be elucidated. In a previous work we identified low levels of PKM2 as a putative oxaliplatin-resistance marker in HT29 CRC cell lines and also in patients. [...]
2015 - 10.1371/journal.pone.0123830
PloS one, Vol. 10, No. 5 (May 2015) , p. e0123830  
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