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Artículos, Encontrados 2 registros

Artículos	Encontrados 2 registros

13 p, 1.4 MB

The site frequency/dosage spectrum of autopolyploid populations / Ferretti, Luca (The Pirbright Institute (Regne Unit)) ; Ribeca, Paolo (The Pirbright Institute (Regne Unit)) ; Ramos-Onsins, Sebastian (Centre de Recerca en Agrigenòmica)
The Site Frequency Spectrum (SFS) and the heterozygosity of allelic variants are among the most important summary statistics for population genetic analysis of diploid organisms. We discuss the generalization of these statistics to populations of autopolyploid organisms in terms of the joint Site Frequency/Dosage Spectrum and its expected value for autopolyploid populations that follow the standard neutral model. [...]
2018 - DOI (Digital Object Identifier)

10.3389/fgene.2018.00480
Frontiers in genetics, Vol. 9 (Oct. 2018) , art. 480

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25 p, 1.2 MB

A generalized Watterson estimator for next-generation sequencing : from trios to autopolyploids / Ferretti, Luca (Université Pierre et Marie CURIE) ; Ramos-Onsins, Sebastian (Centre de Recerca en Agrigenòmica)
Several variations of the Watterson estimator of variability for Next Generation Sequencing (NGS) data have been proposed in the literature. We present a unified framework for generalized Watterson estimators based on Maximum Composite Likelihood, which encompasses most of the existing estimators. [...]
2015 - DOI (Digital Object Identifier)

10.1016/j.tpb.2015.01.001
Theoretical population biology, Vol. 100 (March 2015) , p. 79-87

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