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13 p, 3.8 MB |
Immunogenicity of Mycobacterial Extracellular Vesicles Isolated From Host-Related Conditions Informs About Tuberculosis Disease Status
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Schirmer, Sebastian (University of Applied Sciences. Department of Medical Engineering and Biotechnology) ;
Rauh, Lucas (University of Applied Sciences. Department of Medical Engineering and Biotechnology) ;
Alebouyeh, Sogol (Universidad Autónoma de Madrid. Departamento de Medicina Preventiva y Salud Pública) ;
Delgado-Velandia, Mario (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Salgueiro, Vivian C. (Universidad Autónoma de Madrid. Departamento de Medicina Preventiva y Salud Pública) ;
Lerma, Laura (Universidad Autónoma de Madrid. Departamento de Medicina Preventiva y Salud Pública) ;
Serrano-Mestre, José L. (Universidad Autónoma de Madrid. Departamento de Medicina Preventiva y Salud Pública) ;
Azkargorta, Mikel (Basque Research and Technology Alliance) ;
Elortza, Félix (Basque Research and Technology Alliance) ;
Lavín, José L. (Basque Research and Technology Alliance) ;
García, Maria Jesus (Universidad Autónoma de Madrid. Departamento de Medicina Preventiva y Salud Pública) ;
Tórtola Fernández, María Teresa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Gola, Susanne (University of Applied Sciences. Department of Medical Engineering and Biotechnology) ;
Prados-Rosales, Rafael (Universidad Autónoma de Madrid. Departamento de Medicina Preventiva y Salud Pública)
Tuberculosis (TB) still represents a major global health problem affecting over 10 million people worldwide. The gold-standard procedures for TB diagnosis are culture and nucleic acid amplification techniques. [...]
2022 -  10.3389/fmicb.2022.907296
Frontiers in microbiology, Vol. 13 (June 2022) , art. 907296
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17 p, 1.6 MB |
SirT7 auto-ADP-ribosylation regulates glucose starvation response through mH2A1
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Simonet, Nicolas G.. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Thackray, J. K. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ;
Vazquez Prat, Berta Nieves (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Ianni, A. (Max Planck Institute for Heart and Lung Research. Department of Cardiac Development and Remodelling) ;
Espinosa-Alcantud, María Dolores (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Morales-Sanfrutos, J. (Universitat Pompeu Fabra) ;
Hurtado-Bagès, Sarah. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Sabidó, Eduard (Universitat Pompeu Fabra) ;
Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Tischfield, J. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ;
De La Torre Gómez, Gisela Carolina (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Braun, T. (Max Planck Institute for Heart and Lung Research. Department of Cardiac Development and Remodelling) ;
Olivella, Mireia (Universitat de Vic. Facultat de Ciències i Tecnologia) ;
Serrano, L. (Department of Science. BMCC. City University of New York (CUNY)) ;
Vaquero, Alejandro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Universitat Autònoma de Barcelona
Sirtuins are key players of metabolic stress response. Originally described as deacetylases, some sirtuins also exhibit poorly understood mono-adenosine 5'-diphosphate (ADP)-ribosyltransferase (mADPRT) activity. [...]
2020 - 10.1126/sciadv.aaz2590
Science advances, Vol. 6 Núm. 30 (july 2020) , p. aaz2590
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42 p, 1.6 MB |
A step forward to improve recombinant protein production in Pichia pastoris : from specific growth rate effect on protein secretion to carbon-starving conditions as advanced strategy
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Garcia-Ortega, Xavier (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ;
Adelantado Vallvé, Núria (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ;
Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ;
Montesinos Seguí, José Luis (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ;
Valero Barranco, Francisco (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
The recombinant protein production platform based on the GAP promoter and Pichia pastoris as a host has become a very promising system from an industrial point of view. The need for highly productive bioprocesses gives grounds for the optimization of fermentation strategies maximizing yields and/or productivities, which are often associated with cell growth. [...]
2016 - 10.1016/j.procbio.2016.02.018
Process biochemistry, Vol. 51, Issue 3 (March 2016) , p.
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4.
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13 p, 2.9 MB |
Cell survival during complete nutrient deprivation depends on lipid droplet-fueled beta-oxidation of fatty acids
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González Cabodevilla, Ainara (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Sanchez Caballero, Laura (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Nintou, Eleni (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Georgieva Boiadjieva, Violeta (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Picatoste Ramón, Fernando (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Gubern Burset, Albert (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Claro Izaguirre, Enrique (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Cells exposed to stress of different origins synthesize triacylglycerols and generate lipid droplets (LD), but the physiological relevance of this response is uncertain. Using complete nutrient deprivation of cells in culture as a simple model of stress, we have addressed whether LD biogenesis has a protective role in cells committed to die. [...]
2013 - 10.1074/jbc.M113.466656
Journal of biological chemistry, Vol. 288, Num. 39 (September 2013) , p. 27777-27788
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5.
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30 p, 2.3 MB |
Responses of two semiarid conifer tree species to reduced precipitation and warming reveal new perspectives for stomatal regulation
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Garcia-Forner, Núria (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Adams, Henry D. (Los Alamos National Laboratory) ;
Sevanto, Sanna (Los Alamos National Laboratory) ;
Collins, Adam D. (Los Alamos National Laboratory) ;
Dickman, Lee T. (Los Alamos National Laboratory) ;
Hudson, Patrick J. (University of New Mexico) ;
Zeppe, Melanie (Macquarie University) ;
Martínez Vilalta, Jordi, 1975- (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
McDowell, Nate G. (Los Alamos National Laboratory)
Relatively anisohydric species are predicted to be more predisposed to hydraulic failure than relatively isohydric species, as they operate with narrower hydraulic safety margins. We subjected co-occurring anisohydric Juniperus monosperma and isohydric Pinus edulis trees to warming, reduced precipitation, or both, and measured their gas exchange and hydraulic responses. [...]
2016 - 10.1111/pce.12588
Plant, cell & environment, Vol. 39, Issue 1 (Jan. 2016) , p. 38-49
2 documents
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11 p, 609.4 KB |
Potassium starvation in yeast : mechanisms of homeostasis revealed by mathematical modeling
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Kahm, Matthias (University of Applied Sciences. Department of Mathematics and Technology (Koblenz, Alemanya)) ;
Navarrete, Clara (Universidad de Córdoba. Departamento de Química Agrícola, Edafología y Microbiología) ;
Llopis Torregrosa, Vicent (Instituto de Biologia Molecular y Celular de Plantas (València, Espanya)) ;
Herrera, Rito (Universidad de Córdoba. Departamento de Química Agrícola, Edafología y Microbiología) ;
Barreto, Lina (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Yenush, Lynne (Instituto de Biologia Molecular y Celular de Plantas (València, Espanya)) ;
Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Ramos, José (Universidad de Córdoba. Departamento de Química Agrícola, Edafología y Microbiología) ;
Kschischo, Maik (University of Applied Sciences. Department of Mathematics and Technology (Koblenz, Alemanya))
The intrinsic ability of cells to adapt to a wide range of environmental conditions is a fundamental process required for survival. Potassium is the most abundant cation in living cells and is required for essential cellular processes, including the regulation of cell volume, pH and protein synthesis. [...]
2012 - 10.1371/journal.pcbi.1002548
PLOS Computational Biology, Vol. 8, Issue 6 (June 2012) , p. e1002548
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