Resultados globales: 21 registros encontrados en 0.02 segundos.
Artículos, Encontrados 12 registros
Documentos de investigación, Encontrados 9 registros
Artículos Encontrados 12 registros  1 - 10siguiente  ir al registro:
1.
10 p, 595.1 KB Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in patients with newly diagnosed malignant glioma / Wick, Antje (Heidelberg University Medical Center. Clinical Cooperation Unit Neuro-oncology, German Cancer Research Center) ; Desjardins, Annick (Duke University. The Preston Robert Tisch Brain Tumor Center at Duke) ; Suarez, Cristina (VHIO) ; Forsyth, Peter (H. Lee Moffitt Cancer Center and Research Institute) ; Gueorguieva, Ivelina (Eli Lilly and Company) ; Burkholder, Tiana (Eli Lilly and Company) ; Cleverly, Ann Louise (Eli Lilly and Company) ; Estrem, Shawn T. (Eli Lilly and Company) ; Wang, Shuaicheng (BioStat Solutions, Inc, Frederick, MD USA) ; Lahn, Michael M. (Eli Lilly and Company) ; Guba, Susan C. (Eli Lilly and Company) ; Capper, David (Department of Neuropathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany) ; Rodon Ahnert, Jordi (VHIO) ; Universitat Autònoma de Barcelona
The online version of this article (10. 1007/s10637-020-00910-9) contains supplementary material, which is available to authorized users.
2020 - 10.1007/s10637-020-00910-9
Investigational New Drugs, Vol. 38 (march 2020) , p. 1570-1579  
2.
Oxidized Low-Density Lipoprotein Receptor in Lymphocytes Prevents Atherosclerosis and Predicts Subclinical Disease / Tsilingiri, K. (Vascular Pathophysiology Area. Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; De La Fuente, H. (CIBER de Enfermedades Cardiovasculares) ; Relaño, M. (Vascular Pathophysiology Area. Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Sánchez-Díaz, R. (CIBER de Enfermedades Cardiovasculares) ; Rodríguez, C. (Institut d'Investigació Biomèdica Sant Pau) ; Crespo, J. (Institut d'Investigació Biomèdica Sant Pau) ; Sánchez-Cabo, F. (Bioinformatics Unit. Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Dopazo, A. (Genomics Unit. Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Alonso-Lebrero, J.L. (Department of Immunology. Instituto de Investigación Sanitaria Hospital de la Princesa. IIS-IP) ; Vara, A. (Department of Immunology. Instituto de Investigación Sanitaria Hospital de la Princesa. IIS-IP) ; Vázquez, J. (CIBER de Enfermedades Cardiovasculares) ; Casasnovas, J.M. (Centro Nacional de Biotecnología) ; Alfonso, F. (Department of Cardiology. Instituto de Investigación Sanitaria Hospital de la Princesa. IIS-IP) ; Ibáñez, B. (CIBER de Enfermedades Cardiovasculares) ; Fuster, V. (Cardiovascular Institute. Icahn School of Medicine at Mount Sinai) ; Martínez-González, J. (Institut d'Investigació Biomèdica Sant Pau) ; Martín, P. (CIBER de Enfermedades Cardiovasculares) ; Sánchez-Madrid, F. (CIBER de Enfermedades Cardiovasculares) ; Universitat Autònoma de Barcelona
Background: Although the role of Th17 and regulatory T cells in the progression of atherosclerosis has been highlighted in recent years, their molecular mediators remain elusive. We aimed to evaluate the association between the CD69 receptor, a regulator of Th17/regulatory T cell immunity, and atherosclerosis development in animal models and in patients with subclinical disease. [...]
2019 - 10.1161/CIRCULATIONAHA.118.034326
Circulation, Vol. 139 Núm. 2 (august 2019) , p. 243-255  
3.
15 p, 2.0 MB Monitoring t-cell responses in translational studies: optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-specific responses / Brinke, Anja ten (Sanquin Research (Amsterdam)) ; Marek-Trzonkowska,Natalia (Medical University of Gdansk. Department of Family Medicine) ; Mansilla López, María José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Turksma, Annelies W. (Sanquin Research (Amsterdam)) ; Piekarska, Karolina (Medical University of Gdansk. Department of Family Medicine) ; Iwaszkiewicz-Grzes, Dorota (Medical University of Gdansk. Department of Clinical Immunology and Transplantology) ; Passerini, Laura (IRCCS San Raffaele Scientific Institute) ; Locafaro, Grazia (IRCCS San Raffaele Scientific Institute) ; Puñet Ortiz, Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; van Ham, S. Marieke (Sanquin Research (Amsterdam)) ; Hernandez Fuentes, Maria P. (MRC Centre for Transplantation, King's College London) ; Martínez Cáceres, Eva M. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gregori, Silvia (IRCCS San Raffaele Scientific Institute) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
Adoptive therapy with regulatory T cells or tolerance-inducing antigen (Ag)- presenting cells is innovative and promising therapeutic approach to control undesired and harmful activation of the immune system, as observed in autoimmune diseases, solid organ and bone marrow transplantation. [...]
2017
Frontiers in immunology, Vol. 8 (december 2017) , p. 1-15  
4.
11 p, 1018.7 KB Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects / Hancock, Gemma ; Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Kopycinski, Jakub ; Puertas, Maria C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Giannoulatou, Eleni (University of New South Wales) ; Rose, Annie ; Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hayton, Emma-Jo ; Crook, Alison ; Morgan, Catharine ; Angus, Brian ; Chen, Fabian ; Yang, Hongbing ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hanke, Tomas ; Dorrell, Lucy ; Universitat Autònoma de Barcelona
Introduction : Vaccines may be key components of a curative strategy for HIV-1. We investigated whether a novel immunogen, HIVconsv, designed to re-direct T cell responses to conserved viral epitopes, could impact the HIV-1 reservoir in chronic antiretroviral therapy (ART)-treated subjects when delivered by modified vaccinia virus Ankara (MVA). [...]
2017 - 10.7448/IAS.20.1.21171
Journal of the International AIDS Society, Vol. 20 (may 2017)  
5.
2 p, 165.1 KB Editorial - Glial Cells : Managers of Neuro-Immunity / Barcia, Carlos (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Guillemin, Gilles J. (Macquarie University. Department of Biomedical Sciences) ; Curtin, James F. (Dublin Institute of Technology. School of Food Science & Environmental Health) ; Zirger, Jeffrey M. (U.S. Centers for Disease Control and Prevention) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
After many decades of study in the field of Neuroscience that were mostly centered on the neuron there is a mounting interest in the study of the function of the glial cells in many aspects and functions of the central nervous system. [...]
2016 - 10.3389/fncel.2016.00060
Frontiers in cellular neuroscience, Vol. 10 (March 2016) , art.60  
6.
10 p, 868.0 KB Defining the HLA class I-associated viral antigen repertoire from HIV-1-infected human cells / Ternette, Nicola (University of Oxford. The Jenner Institute, Nuffield Department of Medicine) ; Yang, Hongbing (University of Oxford. Nuffield Department of Medicine) ; Partridge, Thomas (University of Oxford. Nuffield Department of Medicine) ; Llano Montero, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Cedeño, Samandhy (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Fischer, Roman (University of Oxford. Nuffield Department of Medicine) ; Charles, Philip D. (University of Oxford. Nuffield Department of Medicine) ; Dudek, Nadine L. (Monash University. Department of Biochemistry and Molecular Biology) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Crespo, Manuel (Hospital de la Vall d'Hebron. HIV Unit) ; Fischer, William M. (Los Alamos National Laboratory. Group T-6, Theoretical Biology) ; Korber, Bette T. M. (Los Alamos National Laboratory. Group T-6, Theoretical Biology) ; Nielsen, Morten (Technical University of Denmark. Center for Biological Sequence Analysis) ; Borrow, Persephone (University of Oxford. Nuffield Department of Medicine) ; Purcell, Anthony W. (Monash University. Department of Biochemistry and Molecular Biology) ; Brander, Christian (Institució Catalana de Recerca i Estudis Avançats) ; Dorrell, Lucy (University of Oxford. The Jenner Institute, Nuffield Department of Medicine) ; Kessler, Benedikt M. (University of Oxford. Nuffield Department of Medicine) ; Hanke, Tomáš (University of Oxford. The Jenner Institute, Nuffield Department of Medicine) ; Universitat Autònoma de Barcelona
Recognition and eradication of infected cells by cytotoxic T lymphocytes is a key defense mechanism against intracellular pathogens. High-throughput definition of HLA class I-associated immunopeptidomes by mass spectrometry is an increasingly important analytical tool to advance our understanding of the induction of T-cell responses against pathogens such as HIV-1. [...]
2015 - 10.1002/eji.201545890
European Journal of Immunology, Vol. 46 (november 2015) , p. 60-69  
7.
9 p, 2.0 MB Regulatory T cells modulate inflammation and reduce infarct volume in experimental brain ischaemia / Brea, David (Institut Germans Trias i Pujol) ; Agulla, Jesús (Instituto de Investigación Biomédica de Salamanca, Hospital Universitario de Salamanca) ; Rodríguez-Yáñez, Manuel (Instituto de Investigacións Sanitarias de Santiago) ; Barral, David (Instituto de Investigacións Sanitarias de Santiago) ; Ramos-Cabrer, Pedro (Instituto de Investigacións Sanitarias de Santiago) ; Campos, Francisco (Instituto de Investigacións Sanitarias de Santiago) ; Almeida, Angeles (Instituto de Investigación Biomédica de Salamanca, Hospital Universitario de Salamanca) ; Dávalos, Antoni (Institut Germans Trias i Pujol) ; Castillo, José (Instituto de Investigacións Sanitarias de Santiago) ; Universitat Autònoma de Barcelona
Brain ischaemia (stroke) triggers an intense inflammatory response predominately mediated by the accumulation of inflammatory cells and mediators in the ischaemic brain. In this context, regulatory T (Treg) cells, a subpopulation of CD4 + T cells with immunosuppressive and anti-inflammatory properties, are activated in the late stages of the disease. [...]
2014 - 10.1111/jcmm.12304
Journal of Cellular and Molecular Medicine, Vol. 18 (may 2014) , p. 1571-1579  
8.
22 p, 1.1 MB Type 1 diabetes prevention in NOD mice by targeting DPPIV/CD26 is associated with changes in CD8+T effector memory subset / Alonso Pedrol, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Julián, María Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Carrascal, Jorge (Institut Germans Trias i Pujol) ; Colobrán Oriol, Roger (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Pujol Autonell, Irma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rodriguez Fernandez, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Teniente Serra, Aina (Institut Germans Trias i Pujol) ; Fernández Sanmartin, Marco Antonio (Institut Germans Trias i Pujol) ; Miñarro Alonso, Antoni (Universitat de Barcelona. Departament d'Estadística) ; Ruiz de Villa, María del Carmen (Universitat de Barcelona. Departament d'Estadística) ; Vives Pi, Marta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Puig Domingo, Manuel Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona. Departament de Medicina
CD26 is a T cell activation marker consisting in a type II transmembrane glycoprotein with dipeptidyl peptidase IV (DPPIV) activity in its extracellular domain. It has been described that DPPIV inhibition delays the onset of type 1 diabetes and reverses the disease in non-obese diabetic (NOD) mice. [...]
2015 - 10.1371/journal.pone.0142186
PloS one, Vol. 10, Issue 11 (Novembre 2015) , p. e0142186  
9.
19 p, 1.2 MB Use of autoantigen-loaded phosphatidylserine-liposomes to arrest autoimmunity in type 1 diabetes / Pujol Autonell, Irma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Serracant Prat, Arnau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cano-Sarabia, Mary (Institut Català de Nanociència i Nanotecnologia) ; Ampudia, Rosa Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rodriguez Fernandez, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sànchez, Àlex (Sànchez Pla) (Universitat de Barcelona. Departament d'Estadística) ; Izquierdo Castro, Cristina (Universitat de Barcelona. Departament de Fisiologia i Immunologia) ; Stratmann, Thomas (Universitat de Barcelona. Departament de Fisiologia i Immunologia) ; Puig Domingo, Manuel Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Verdaguer, Joan (Universitat de Lleida. Departament de Medicina Experimental) ; Vives Pi, Marta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona
INTRODUCTION: The development of new therapies to induce self-tolerance has been an important medical health challenge in type 1 diabetes. An ideal immunotherapy should inhibit the autoimmune attack, avoid systemic side effects and allow β-cell regeneration. [...]
2015 - 10.1371/journal.pone.0127057
PloS one, Vol. 19, Issue 6 (June 2015) , p. e0127057  
10.
21 p, 2.1 MB Natural Polymorphisms in Tap2 Influence Negative Selection and CD4:CD8 Lineage Commitment in the Rat / Tuncel, Jonatan (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Haag, Sabrina (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Yau, Anthony C. (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Norin, Ulrika (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Baud, Amelie (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Lönnblom, Erik (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Maratou, Klio (Imperial College London) ; Ytterberg, A. Jimmy (Karolinska University Hospital) ; Ekman, Diana (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Thordardottir, Soley (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Johannesson, Martina (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Gillett, Alan (Karolinska University Hospital) ; Stridh, Pernilla (Karolinska University Hospital) ; Jagodic, Maja (Karolinska University Hospital) ; Olsson, Tomas (Karolinska University Hospital) ; Fernández-Teruel, Albert (Universitat Autònoma de Barcelona. Departament de Psiquiatria i Medicina Legal) ; Zubarev, Roman A. (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Mott, Richard (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Aitman, Timothy J. (Imperial College London) ; Flint, Jonathan (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Holmdahl, Rikard (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; EURATRANS Consortium
Genetic variation in the major histocompatibility complex (MHC) affects CD4∶CD8 lineage commitment and MHC expression. However, the contribution of specific genes in this gene-dense region has not yet been resolved. [...]
2014 - 10.1371/journal.pgen.1004151
PLoS Genetics, Vol. 10 Issue 2 (February 2014) , p. e1004151  

Artículos : Encontrados 12 registros   1 - 10siguiente  ir al registro:
Documentos de investigación Encontrados 9 registros  
1.
1 p, 852.4 KB APC Vaccines in iNKT Cell-Mediated Antitumoral Immunotherapy / Garcia Ortega, Sara ; Universitat Autònoma de Barcelona. Facultat de Biociències
2018
Grau en Ciències Biomèdiques [832]  
2.
1 p, 751.8 KB Type 1 diabetes mellitus immunotherapy : using regulatory T cells to balance the immune response / Crespo Galván, Raquel ; Álvarez, Iñaki, dir., (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2017
Grau en Microbiologia [816]  
3.
1 p, 682.5 KB Natural killer T cell-based immunotherapy for cancer / Vila Gatius, Jaume ; Castaño García, A. Raúl, (Ángel Raúl) dir., (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2017
Grau en Biologia [812]  
4.
1 p, 491.8 KB Proposal of a research project : use mesenchymal stem cell derived exosomes targeted to T cells and charged with specific miRNA as a therapeutic tool against type 1 diabetes / Vicente Rizo, Sílvia ; Roher Armentia, Nerea (Universitat Autònoma de Barcelona. Departament de Biologia, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Bioquímica [814]  
5.
1 p, 2.1 MB Antitumoral immune response : NKT cell-mediated immunotherapy / Montpeyó Garcia-Moreno, Marta ; Castaño García, A. Raúl, (Ángel Raúl) dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Ciències Biomèdiques [832]  
6.
1 p, 741.0 KB Chimeric antigen receptor-engineered T cells for B acute lymphocytic leukemia / Altadill Ferrando, Cinta ; Bosch i Merino, Assumpció, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Ciències
2015
Grau en Biotecnologia [815]  
7.
1 p, 366.8 KB Invariant natural killer T cells as anti-tumour immunotherapy / Segura Martínez, Laura ; Castaño García, A. Raúl, (Ángel Raúl) dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Ciències Biomèdiques [832]  
8.
1 p, 662.5 KB Immunosupression induced by cancer cells : PD-1 and CTLA-4 pathways / Soliveras Sintes, Miriam ; Jaraquemada, Dolores, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Bioquímica [814]  
9.
1 p, 523.9 KB Cancer treatment with chimeric antigen receptor (CAR)-T cells / Arasanz Armengol, Monica ; Bosch i Merino, Assumpció, dir., (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Genètica [833]  

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