Resultats globals: 12 registres trobats en 0.03 segons.
Articles, 7 registres trobats
Documents de recerca, 5 registres trobats
Articles 7 registres trobats  
1.
11 p, 1.5 MB Comparison of flow-FISH and MM-qPCR telomere length assessment techniques for the screening of telomeropathies / Ferreira, M.S.V. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Kirschner, M. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Halfmeyer, I. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Estrada, Natalia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Xicoy, Blanca (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Isfort, S. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Vieri, M. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Zamora, Lurdes (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Abels, A. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Bouillon, A.S. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Begemann, M. (Institute of Human Genetics. Medical Faculty. RWTH Aachen University) ; Schemionek, M. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Maurer, A. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Koschmieder, S. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Wilop, S. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Panse, J. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Brümmendorf, T.H. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Beier, F. (Department of Hematology. Oncology. Hemostaseology and Stem Cell Transplantation. Medical Faculty. RWTH Aachen University. University Hospital Aachen) ; Universitat Autònoma de Barcelona
Assessment of telomere length (TL) in peripheral blood leukocytes is part of the diagnostic algorithm applied to patients with acquired bone marrow failure syndromes (BMFSs) and dyskeratosis congenita (DKC). [...]
2020 - 10.1111/nyas.14248
Annals of the New York Academy of Sciences, Vol. 1466 Núm. 1 (2020) , p. 93-103  
2.
12 p, 3.3 MB Genetic analyses of aplastic anemia and idiopathic pulmonary fibrosis patients with short telomeres, possible implication of DNA-repair genes / Arias-Salgado, E.G. (Advanced Medical Projects) ; Galvez, E. (Hospital Niño Jesús. Hematología y Hemoterapia) ; Planas-Cerezales, L. (ILD Unit Pneumology Department. University Hospital of Bellvitge. IDIBELL. University of Barcelona) ; Pintado-Berninches, L. (Advanced Medical Projects) ; Vallespin, E. (Institute of Medical and Molecular Genetics (INGEMM). Hospital Universitario la Paz) ; Martinez, P. (Institute of Medical and Molecular Genetics (INGEMM). Hospital Universitario la Paz) ; Carrillo, J. (Instituto de Investigaciones Biomedicas CSIC/UAM. IDIPaz) ; Iarriccio, L. (Advanced Medical Projects) ; Ruiz-Llobet, A. (Institut de Recerca Pediàtrica Hospital Sant Joan de Déu (IRP-HSJD). Esplugues de Llobregat) ; Catalá, A. (Institut de Recerca Pediàtrica Hospital Sant Joan de Déu (IRP-HSJD). Esplugues de Llobregat) ; Badell-Serra, I. (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Gonzalez-Granado, L.I. (Hospital 12 de Octubre (Madrid)) ; Martín-Nalda, A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martínez-Gallo, M. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Galera-Miñarro, A. (Hospital Universitario Virgen de la Arrixaca) ; Rodríguez-Vigil, C. (Hospital Miguel Servet) ; Bastos-Oreiro, M. (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ; Perez De Nanclares, G. (Molecular (Epi)Genetics Laboratory. BioAraba National Health Institute. OSI Araba University Hospital) ; Leiro-Fernández, V. (Pneumology Department. Hospital Álvaro Cunqueiro. Complexo Hospitalario Universitario de Vigo. NeumoVigoI+i Research Group. Vigo Biomedical Research Institute (IBIV)) ; Uria, M.L. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Diaz-Heredia, C. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Valenzuela, C. (Hospital de la Princesa) ; Martín, S. (ILD Unit Pneumology Department. University Hospital of Bellvitge. IDIBELL. University of Barcelona) ; López-Muñiz, B. (Hospital Infanta Leonor) ; Lapunzina, P. (CIBER de Enfermedades Raras (CIBERER)) ; Sevilla, J. (CIBER de Enfermedades Raras (CIBERER)) ; Molina-Molina, M. (CIBER of Respiratory Diseases (CIBERES)) ; Perona, R. (CIBER de Enfermedades Raras (CIBERER)) ; Sastre, L. (CIBER de Enfermedades Raras (CIBERER))
Background: Telomeres are nucleoprotein structures present at the terminal region of the chromosomes. Mutations in genes coding for proteins involved in telomere maintenance are causative of a number of disorders known as telomeropathies. [...]
2019 - 10.1186/s13023-019-1046-0
Orphanet Journal of Rare Diseases, Vol. 14 Núm. 1 (17 2019) , p. 82  
3.
14 p, 5.0 MB Single-cell telomere-length quantification couples telomere length to meristem activity and stem cell development in Arabidopsis / González-García, Mary Paz (Centre de Recerca en Agrigenòmica) ; Pavelescu, Irina (Centre de Recerca en Agrigenòmica) ; Canela, Andrés (Centro Nacional de Investigaciones Oncológicas. Grupo de Telómeros y Telomerasa) ; Sevillano, Xavier (Universitat Ramon Llull. Grup de Recerca en Tecnologies Mèdia) ; Leehy, Katherine A. (Texas A&M University. Department of Biochemistry and Biophysics) ; Nelson, Andrew D.L. (Texas A&M University. Department of Biochemistry and Biophysics) ; Ibañes, Marta (Universitat de Barcelona. Departament d'Estructura i Constituents de la Matèria) ; Shippen, Dorothy E. (Texas A&M University. Department of Biochemistry and Biophysics) ; Blasco, María A. (Centro Nacional de Investigaciones Oncológicas. Grupo de Telómeros y Telomerasa) ; Caño Delgado, Ana I. (Centre de Recerca en Agrigenòmica)
Telomeres are specialized nucleoprotein caps that protect chromosome ends assuring cell division. Single-cell telomere quantification in animals established a critical role for telomerase in stem cells, yet, in plants, telomere-length quantification has been reported only at the organ level. [...]
2015 - 10.1016/j.celrep.2015.04.013
Cell reports, Vol. 11, issue 6 (May 2015) , p. 977-989  
4.
8 p, 964.1 KB Telomere attrition in heart failure : a flow-FISH longitudinal analysis of circulating monocytes / Teubel, Iris (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Elchinova, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Roura, Santiago (Madrid, Spain) ; Fernández, Marco A. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Moliner, Pedro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; de Antonio, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Lupón, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Cross-sectional investigations report shorter telomeres in patients with heart failure (HF); however, no studies describe telomere length (TL) trajectory and its relationship with HF progression. Here we aimed to investigate telomere shortening over time and its relationship to outcomes. [...]
2018 - 10.1186/s12967-018-1412-z
Journal of translational medicine, Vol. 16 (february 2018)  
5.
19 p, 1.9 MB Centrosome aberrations in human mammary epithelial cells driven by cooperative interactions between p16 INK4a deficiency and telomere-dependent genotoxic stress / Domínguez, Daniel (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Feijoo, Purificación (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Bernal, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Ercilla, Amaia (Universitat de Barcelona) ; Agell, Neus (Universitat de Barcelona) ; Genescà, A. (Anna) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Tusell Padrós, Laura (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Virtually all human cancers display chromosome instability (CIN), a condition in which chromosomes are gained or lost at a high rate. CIN occurs early in cancer development where it may undermine the advance of the neoplastic disease. [...]
2015 - 10.18632/oncotarget.4958
Oncotarget, Vol. 6 Núm. 29 (July 2015) , p. 28238-28256  
6.
15 p, 857.4 KB Dyslipidemia and chronic inflammation markers are correlated with telomere length shortening in Cushing's syndrome / Aulinas Masó, Anna (Institut d'Investigació Biomèdica Sant Pau) ; Ramírez de Haro, Ma. José (María José) (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Barahona Constanzo, María José (Hospital Mútua de Terrassa. Departament d'Endocrinologia) ; Valassi, Elena (Institut d'Investigació Biomèdica Sant Pau) ; Resmini, Eugenia (Institut d'Investigació Biomèdica Sant Pau) ; Mato, Eugènia (Institut d'Investigació Biomèdica Sant Pau) ; Santos, Alicia (Institut d'Investigació Biomèdica Sant Pau) ; Crespo, Iris (Institut d'Investigació Biomèdica Sant Pau) ; Bell, Olga (Institut d'Investigació Biomèdica Sant Pau) ; Surrallés i Calonge, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Webb, S. M. q (Susan M.), 1952- (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
INTRODUCTION: Cushing's syndrome (CS) increases cardiovascular risk (CVR) and adipocytokine imbalance, associated with an increased inflammatory state. Telomere length (TL) shortening is a novel CVR marker, associated with inflammation biomarkers. [...]
2015 - 10.1371/journal.pone.0120185
PloS one, Vol. 10, Issue 3 (March 2015) , p. e0120185.  
7.
12 p, 1.1 MB Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patients / Joksic, Ivana (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia)) ; Vujic, Dragana (University of Belgrade. School of Medicine (Belgrad, Sèrbia)) ; Guc-Scekic, Marija (Mother and Child Health Care Institute of Serbia "Dr Vukan Cupic" (Belgrad, Sèrbia)) ; Leskovac, Andreja (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia)) ; Petrovic, Sandra (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia)) ; Ojani, Maryam (Brunel University (Londres, Regne Unit)) ; Trujillo Quintero, Juan Pablo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Surrallés i Calonge, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Zivkovic, Maja (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia)) ; Stankovic, Aleksandra (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia)) ; Slijepcevic, Pedrag (Brunel University (Londres, Regne Unit)) ; Joksic, Gordana (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia))
Background: Fanconi anemia (FA) is characterized by sensitivity to DNA cross-linking agents, mild cellular, and marked clinical radio sensitivity. In this study we investigated telomeric abnormalities of non-immortalized primary cells (lymphocytes and fibroblasts) derived from FA patients of the FA-D2 complementation group, which provides a more accurate physiological assessment than is possible with transformed cells or animal models. [...]
2012 - 10.1186/2041-9414-3-6
Genome integrity, Vol. 3, N. 6 (September 2012) , p. 1-12  

Documents de recerca 5 registres trobats  
1.
138 p, 2.9 MB Investigation of the telomere maintenance system in Cushing's syndrome: A contribution to the phenomena of early ageing and specific morbidity / Aulinas Masó, Anna ; Webb, S. M. 1952-, (Susan M.) dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
La síndrome de Cushing (SC), una malaltia minoritària per secreció excessiva de cortisol, s'associa a augment de morbi-mortalitat, inclús després del tractament, comparat amb població de referència i s'associa a processos d'envelliment prematur. [...]
Cushing's syndrome (CS), a rare disease due to excessive cortisol secretion, is associated with increased morbidity and mortality, even after therapy compared to background population and is associated with premature aging processes. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2015  
2.
1 p, 1002.9 KB The role of shelterin in cellular senescense and systemic aging / Chen, Qian ; Genescà, A., (Anna), dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Ciències Biomèdiques [832]  
3.
1 p, 675.8 KB Telomerase and aging : a lifestyle lesson / Xandri i Monje, Helena ; Genescà, A., (Anna), dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Bioquímica [814]  
4.
1 p, 1.2 MB Telomeres : cancer or eternal youth ? / Pons, Maria ; Genescà, A., (Anna), dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Bioquímica [814]  
5.
1 p, 4.6 MB Telomeres and telomerase : source of eternal youth ? / Rico Sorlí, Ana ; Genescà, A., (Anna), dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Bioquímica [814]  

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