Resultados globales: 6 registros encontrados en 0.02 segundos.
Artículos, Encontrados 5 registros
Documentos de investigación, Encontrados 1 registros
Artículos Encontrados 5 registros  
1.
12 p, 1.1 MB The role of the interleukin-23/Th17 pathway in cardiometabolic comorbidity associated with psoriasis / Egeberg, A. (Gentofte Hospital) ; Gisondi, P. (University of Verona) ; Carrascosa, Jose Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Warren, R.B. (Manchester NIHR Biomedical Research Centre) ; Mrowietz, U. (University Medical Center Schleswig-Holstein) ; Universitat Autònoma de Barcelona
Alterations in the innate and adaptive immunity underpin psoriasis pathophysiology, with the Th17 cells subset now recognized as the fundamental cells in the key controlling pathway involved in its pathogenesis. [...]
2020 - 10.1111/jdv.16273
Journal of the European Academy of Dermatology and Venereology, Vol. 34 (march 2020) , p. 1695-1706  
2.
Oxidized Low-Density Lipoprotein Receptor in Lymphocytes Prevents Atherosclerosis and Predicts Subclinical Disease / Tsilingiri, K. (Vascular Pathophysiology Area. Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; De La Fuente, H. (CIBER de Enfermedades Cardiovasculares) ; Relaño, M. (Vascular Pathophysiology Area. Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Sánchez-Díaz, R. (CIBER de Enfermedades Cardiovasculares) ; Rodríguez, C. (Institut d'Investigació Biomèdica Sant Pau) ; Crespo, J. (Institut d'Investigació Biomèdica Sant Pau) ; Sánchez-Cabo, F. (Bioinformatics Unit. Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Dopazo, A. (Genomics Unit. Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Alonso-Lebrero, J.L. (Department of Immunology. Instituto de Investigación Sanitaria Hospital de la Princesa. IIS-IP) ; Vara, A. (Department of Immunology. Instituto de Investigación Sanitaria Hospital de la Princesa. IIS-IP) ; Vázquez, J. (CIBER de Enfermedades Cardiovasculares) ; Casasnovas, J.M. (Centro Nacional de Biotecnología) ; Alfonso, F. (Department of Cardiology. Instituto de Investigación Sanitaria Hospital de la Princesa. IIS-IP) ; Ibáñez, B. (CIBER de Enfermedades Cardiovasculares) ; Fuster, V. (Cardiovascular Institute. Icahn School of Medicine at Mount Sinai) ; Martínez-González, J. (Institut d'Investigació Biomèdica Sant Pau) ; Martín, P. (CIBER de Enfermedades Cardiovasculares) ; Sánchez-Madrid, F. (CIBER de Enfermedades Cardiovasculares) ; Universitat Autònoma de Barcelona
Background: Although the role of Th17 and regulatory T cells in the progression of atherosclerosis has been highlighted in recent years, their molecular mediators remain elusive. We aimed to evaluate the association between the CD69 receptor, a regulator of Th17/regulatory T cell immunity, and atherosclerosis development in animal models and in patients with subclinical disease. [...]
2019 - 10.1161/CIRCULATIONAHA.118.034326
Circulation, Vol. 139 Núm. 2 (august 2019) , p. 243-255  
3.
12 p, 4.5 MB Clinical and Histopathological Amelioration of Experimental Autoimmune Encephalomyelitis by AAV Vectors Expressing a Soluble Interleukin-23 Receptor / Miralles, Marta (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Eixarch, Herena (Hospital universitari Vall Hebron. Institut de Recerca) ; Tejero, Marcos (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Costa, Carme (Hospital universitari Vall Hebron. Institut de Recerca) ; Hirota, Keiji (National Institute for Medical Research) ; Castaño, A. Raul (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Puig, Meritxell (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Stockinger, Gitta (National Institute for Medical Research) ; Montalban, Xavier (Hospital universitari Vall Hebron. Institut de Recerca) ; Bosch, Assumpció (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Espejo, Carmen (Hospital universitari Vall Hebron. Institut de Recerca) ; Chillon, Miguel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
The role of the T helper (Th)17 pathway has been clearly demonstrated in the onset and progression of autoimmune diseases, where interleukin (IL)-23 is a key molecule in maintaining the response mediated by Th17 cells. [...]
The online version of this article (doi:10. 1007/s13311-017-0545-8) contains supplementary material, which is available to authorized users.

2017 - 10.1007/s13311-017-0545-8
Neurotherapeutics, Vol. 14 (June 2017) , p. 1095-1106  
4.
13 p, 2.5 MB Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control / Ruiz-Riol, M. (Institut Germans Trias i Pujol) ; Berdnik, D. ; Llano, A. (Institut Germans Trias i Pujol) ; Mothe, Beatriz. (Institut Germans Trias i Pujol) ; Gálvez, C. (Institut Germans Trias i Pujol) ; Pérez-Álvarez, S. (Institut Germans Trias i Pujol) ; Oriol-Tordera, B. (Institut Germans Trias i Pujol) ; Olvera, A. (Institut Germans Trias i Pujol) ; Silva-Arrieta, S. (Institut Germans Trias i Pujol) ; Meulbroek, M. (Institut Germans Trias i Pujol) ; Pujol, F. ; Coll, J. (Institut Germans Trias i Pujol) ; Martinez-Picado, J. (Institut Germans Trias i Pujol) ; Ganoza, C. ; Sanchez, J. ; Gómez, G. ; Wyss-Coray, T. ; Brander, Christian. (Institut Germans Trias i Pujol)
Intact and broad immune cell effector functions and specific individual cytokines have been linked to HIV disease outcome, but their relative contribution to HIV control remains unclear. We asked whether the proteome of secreted cytokines and signaling factors in peripheral blood can be used to discover specific pathways critical for host viral control. [...]
2017 - 10.1128/JVI.00441-17
Journal of Virology, Vol. 91 (july 2017)  
5.
18 p, 9.9 MB The Small Breathing Amplitude at the Upper Lobes Favors the Attraction of Polymorphonuclear Neutrophils to Mycobacterium tuberculosis Lesions and Helps to Understand the Evolution toward Active Disease in An Individual-Based Model / Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Prats Soler, Clara (Universitat Politècnica de Catalunya. Escola Superior d'Agricultura de Barcelona)
Infection with Mycobacterium tuberculosis (Mtb) can induce two kinds of lesions, namely proliferative and exudative. The former are based on the presence of macrophages with controlled induction of intragranulomatous necrosis, and are even able to stop its physical progression, thus avoiding the induction of active tuberculosis (TB). [...]
2016 - 10.3389/fmicb.2016.00354
Frontiers in microbiology, Vol. 7 Núm. 654 (March 2016)  

Documentos de investigación Encontrados 1 registros  
1.
66 p, 2.0 MB Inmunomodulació de la vía Th17 con vectores virales portadores del receptor soluble de IL23: una nueva estrategia de terapia génica para el tratamiento de sclerosis múltiple / Miralles Consuegra, Marta ; Chillón Rodríguez, Miguel, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
En las últimas décadas, la incidencia de enfermedades autoinmunes ha aumentado notablemente, ya sea por el mayor conocimiento, por la mejora en las herramientas de diagnóstico, o por los cambios en los hábitos de vida. [...]
In the last decades, the incidence of autoimmune diseases has increased significantly, either by the greater knowledge we have of them, by the improvement of diagnostic tools, or by changes in lifestyle. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014
3 documentos

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