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15 p, 1.6 MB |
A trans-omics assessment of gene-gene interaction in early-stage NSCLC
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Chen, Jiajin (Nanjing Medical University) ;
Song, Yunjie (Department of Biostatistics. Nanjing Medical University) ;
Li, Yi (Department of Biostatistics. University of Michigan) ;
Wei, Yongyue (Nanjing Medical University) ;
Shen, Sipeng (Department of Biostatistics. Nanjing Medical University) ;
Zhao, Yang (Department of Biostatistics. Nanjing Medical University) ;
You, Dongfang (Department of Biostatistics. Nanjing Medical University) ;
Su, Li (Harvard Medical School) ;
Bjaanæs, Maria Moksnes (Department of Cancer Genetics Oslo University Hospital) ;
Karlsson, Anna (Department of Clinical Sciences. Lund University) ;
Planck, Maria (Department of Clinical Sciences. Lund University) ;
Staaf, Johan (Department of Clinical Sciences. Lund University) ;
Helland, Åslaug (Institute of Clinical Medicine. University of Oslo) ;
Esteller, M (Universitat de Barcelona) ;
Shen, Hongbing (Nanjing Medical University) ;
Christiani, David C. (Harvard Medical School) ;
Zhang, Ruyang (Nanjing Medical University) ;
Chen, Feng (State Key Laboratory of Reproductive Medicine. Nanjing Medical University)
Epigenome-wide gene-gene (G × G) interactions associated with non-small-cell lung cancer (NSCLC) survival may provide insights into molecular mechanisms and therapeutic targets. Hence, we proposed a three-step analytic strategy to identify significant and robust G × G interactions that are relevant to NSCLC survival. [...]
2023 -  10.1002/1878-0261.13345
Molecular Oncology, Vol. 17 Núm. 1 (january 2023) , p. 173-187
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26 p, 1.1 MB |
Structural and kinetic features of aldehyde dehydrogenase 1A (ALDH1A) subfamily members, cancer stem cell markers active in retinoic acid biosynthesis
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Pequerul Pavon, Raquel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Vera Lillo, Javier (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Giménez Dejoz, Joan (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Crespo, Isidro (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Coines, Joan (Universitat de Barcelona) ;
Porté, Sergio (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Rovira, Carme (Universitat de Barcelona) ;
Parés i Casasampera, Xavier (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Farrés, Jaume (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Aldehyde dehydrogenases catalyze the NAD(P)+-dependent oxidation of aldehydes to their corresponding carboxylic acids. The three-dimensional structures of the human ALDH1A enzymes were recently obtained, while a complete kinetic characterization of them, under the same experimental conditions, is lacking. [...]
2020 - 10.1016/j.abb.2020.108256
Archives of biochemistry and biophysics, Vol. 681 (2020) , p. 108256
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28 p, 796.7 KB |
Dissecting ultra-processed foods and drinks : Do they have a potential to impact the brain?
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Contreras Rodríguez, Oren (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Solanas i Garcia, Montserrat (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Escorihuela Agullo, Rosa Maria (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Ultra-processed foods and drinks (UPF) are formulation of ingredients, mostly of exclusive industrial use, that result from a series of industrial processes. They usually have a low nutrient but high energy density, with a high content of saturated and trans fats, and added sugars. [...]
2022 - 10.1007/s11154-022-09711-2
Reviews in endocrine and metabolic disorders, Vol. 23 Núm. 4 (august 2022) , p. 697-717
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31 p, 920.4 KB |
Chiral pH-sensitive cyclobutane beta-amino acid-based cationic amphiphiles : Possible candidates for use in gene therapy
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Pi i Boleda, Bernat (Universitat Autònoma de Barcelona. Departament de Química) ;
Bouzas, Mireia (Universitat Autònoma de Barcelona. Departament de Química) ;
Gaztelumendi, Nerea (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Illa, Ona (Universitat Autònoma de Barcelona. Departament de Química) ;
Nogués, C. (Carme) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Branchadell Gallo, Vicenç (Universitat Autònoma de Barcelona. Departament de Química) ;
Pons, Ramon (Institut de Química Avançada de Catalunya. Departament de Tensioactius i Nanobiotecnologia) ;
Ortuño Mingarro, Rosa María (Universitat Autònoma de Barcelona. Departament de Química)
Chiral cis/trans diastereomeric cationic amphiphiles have been synthesized and studied. They are based on beta-amino acids and contain C-12- and C-16-alkyl chains, respectively, as hydrophobic tails while the polar head consists of an ammonium cation linked to a cyclobutane ring. [...]
2020 - 10.1016/j.molliq.2019.111856
Journal of Molecular Liquids, Vol. 297 (January 2020) , art. 111856
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19 p, 223.6 KB |
Travestis e Transexuais no Brasil : Memórias de Luta e Resistência
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Souza, Cristiane Prudenciano de (Universidade de Coimbra)
As reflexões do artigo são resultado de uma pesquisa de mestrado realizada no Brasil, nos anos 2015-2018, abordando a luta histórica de travestis e transexuais femininas no espaço do ativismo. Desvendamos as práticas sociais, táticas e estratégias, tendo como foco as conquistas de espaço social e político, como a luta pela visibilidade das principais pautas do movimento trans organizado. [...]
The reflections of the article are the result of a master's research conducted in Brazil, in the years 2015-2018, addressing the historical struggle of female transvestites and transsexuals in the space of activism in the years 2015-2018, addressing the historical struggle of female transvestites and transsexuals in the space of activism. [...]
2023 - 10.5565/rev/qpsicologia.1599
Quaderns de psicologia, Vol. 25 Núm. 1 (2023) , p. e1599 (Artículos)
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15 p, 131.2 KB |
Alumnado trans : una oportunidad para el desarrollo de pedagogías feministas en la escuela
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Sánchez Sáinz, Mercedes (Universidad Complutense de Madrid) ;
García Medina, Raúl (Universidad Complutense de Madrid) ;
Penna Tosso, Melani (Universidad Complutense de Madrid)
Ante la escasez de investigaciones que relacionen el clima escolar con las tasas de éxito de alumnado trans, planteamos este análisis para indagar en las trayectorias que siguen dichos estudiantes en la educación obligatoria y poder identificar factores que puedan contribuir a paliar las elevadas tasas de abandono observadas en este colectivo. [...]
Davant de l'escassetat d'investigacions que relacionin el clima escolar amb les taxes d'èxit d'alumnat trans, plantegem la present anàlisi per explorar les trajectòries que segueixen aquests estudiants a l'educació obligatòria i poder identificar aquells factors que puguin contribuir a pal·liar les elevades taxes d'abandonament observades en aquest sector. [...]
In contrast with the numerous studies focusing on the types of violence suffered by trans people, hardly any studies have looked at the factors associated with academic success among this demographic group. [...]
2023 - 10.5565/rev/educar.1569
Educar, Vol. 59 Núm. 1 (2023) , p. 115-129 (Monográfico)
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12 p, 1.9 MB |
Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease
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Watt, Stephen (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Vasquez, Louella (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Walter, Klaudia (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Mann, Alice L. (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Kundu, Kousik (School of Clinical Medicine. University of Cambridge) ;
Chen, Lu (Sichuan University) ;
Sims, Ying (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Ecker, Simone (UCL Cancer Institute) ;
Burden, Frances (National Health Service Blood and Transplant) ;
Farrow, Samantha (National Health Service Blood and Transplant) ;
Farr, Ben (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Iotchkova, Valentina (University of Oxford) ;
Elding, Heather (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Mead, Daniel (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Tardaguila, Manuel (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Ponstingl, Hannes (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Richardson, David (European Molecular Biology Laboratory. European Bioinformatics Institute) ;
Datta, Avik (European Molecular Biology Laboratory. European Bioinformatics Institute) ;
Flicek, Paul (European Molecular Biology Laboratory. European Bioinformatics Institute) ;
Clarke, Laura (European Molecular Biology Laboratory. European Bioinformatics Institute) ;
Downes, Kate (National Health Service Blood and Transplant) ;
Pastinen, Tomi (Center for Pediatric Genomic Medicine. Children's Mercy) ;
Fraser, Peter (Florida State University) ;
Frontini, Mattia (University of Exeter Medical School) ;
Javierre, B. M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Spivakov, Mikhail (Imperial College Faculty of Medicine) ;
Soranzo, Nicole (University of Cambridge)
Neutrophils play fundamental roles in innate immune response, shape adaptive immunity, and are a potentially causal cell type underpinning genetic associations with immune system traits and diseases. [...]
2021 - 10.1038/s41467-021-22548-8
Nature communications, Vol. 12 Núm. 1 (january 2021) , p. 2298
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10 p, 940.1 KB |
Identifying the winter grounds of the recently described Barbary Reed Warbler (Acrocephalus baeticatus ambiguus)
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Jiguet, Frédéric (Sorbonne Université. Centre d'Écologie et de Sciences de la Conservation) ;
Dufour, Paul (University of Gothenburg. Department of Biological and Environmental Sciences) ;
Kardynal, Kevin J. (Environment and Climate Change Canada) ;
Hobson, Keith A. (University of Western Ontario. Department of Biology and Environment and Climate Change Canada) ;
Copete, José Luis (Universitat Autònoma de Barcelona. Biblioteca de Ciència i Tecnologia) ;
Arroyo, José Luis (Estación Biológica de Doñana. Equipo de Seguimiento de Procesos Naturales) ;
Lee, Raymon W. (Washington State University. School of Biological Science) ;
Rguibi-Idrissi, Hamid (University Md V. Laboratory Biodiversity, Ecology and Genome) ;
Procházka, Petr (Institute of Vertebrate Biology. Czech Academy of Sciences)
The Iberian and North African populations of reed warblers have been described recently as a separate taxon, ambiguus, forming a sister clade to the Sahelian subspecies minor of African Reed Warbler Acrocephalus baeticatus. [...]
2022 - 10.1111/ibi.13113
Ibis, (July 2022) , art. 13113
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10 p, 629.8 KB |
Impact of the COVID-19 Health Crisis on Trans Women and Cis Men Sex Workers in Spain
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Leyva-Moral, Juan M. (Universitat Autònoma de Barcelona. Departament d'Infermeria) ;
Castro Ávila, Juliana (Coalition PLUS) ;
Villar-Salgueiro, Marta (Stop SIDA) ;
López, Beti (Fundació Àmbit Prevenció) ;
Adell, Héctor (Stop SIDA) ;
Meroño, Mercè (Fundació Àmbit Prevenció) ;
Santander, Kevin (Universitat Autònoma de Barcelona. Departament d'Infermeria) ;
Ferrer Serret, Laia (Generalitat de Catalunya. Departament de Salut) ;
Mesías-Gazmuri, Jocelyn (Institut Germans Trias i Pujol) ;
Astudillo Alonso, Rocío (Generalitat de Catalunya. Departament de Salut) ;
Rojas Castro, Daniela (Coalition PLUS) ;
Casabona-Barbarà, Jordi (Institut Germans Trias i Pujol) ;
Folch, Cinta (Institut Germans Trias i Pujol)
The objective of the study was to describe the impact of the COVID-19 pandemic on sex workers in accessing health and social services. A qualitative study was conducted using semi-structured interviews with 29 participants in Barcelona, Spain. [...]
Springer New York, 2022 - 10.1007/s10508-022-02405-5
Archives of Sexual Behavior
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