|
1.
|
|
21 p, 11.5 MB |
Identification of constrained sequence elements across 239 primate genomes
/
Kuderna, Lukas F. K. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Ulirsch, Jacob C. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Rashid, Sabrina (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Ameen, Mohamed (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Sundaram, Laksshman (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Hickey, Glenn (University of California. Santa Cruz Genomics Institute) ;
Cox, Anthony J. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Gao, Hong (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Kumar, Arvind (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Aguet, Francois (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Christmas, Matthew J. (Uppsala University. Department of Medical Biochemistry and Microbiology) ;
Clawson, Hiram (University of California. Santa Cruz Genomics Institute) ;
Haeussler, Maximilian (University of California. Santa Cruz Genomics Institu) ;
Janiak, Mareike C. (University of Salford. School of Science, Engineering and Environment) ;
Kuhlwilm, Martin (University of Vienna. Department of Evolutionary Anthropology) ;
Orkin, Joseph D. (Université de Montréal. Département d'Anthropologie) ;
Bataillon, Thomas (Aarhus University. Bioinformatics Research Centre) ;
Shivakumara Manu (Academy of Scientific and Innovative Research (Ghaziabad, Índia)) ;
Valenzuela, Alejandro (Institut de Biologia Evolutiva (Barcelona)) ;
Bergman, Juraj (Aarhus University. Bioinformatics Research Centre) ;
Rouselle, Marjolaine (Aarhus University. Bioinformatics Research Centre) ;
Silva, Felipe Ennes (Mamirauá Institute for Sustainable Development) ;
Agueda Calpena, Lidia (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
Blanc, Julie (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
Gut, Marta (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
de Vries, Dorien (University of Salford. School of Science, Engineering and Environment) ;
Goodhead, Ian (University of Salford. School of Science, Engineering and Environment) ;
Harris, R. Alan (Baylor College of Medicine. Department of Molecular and Human Genetics) ;
Raveendran, Muthuswamy (Baylor College of Medicine. Department of Molecular and Human Genetics) ;
Jensen, Axel (Uppsala University. Department of Ecology and Genetics) ;
Chuma, Idriss S. (Tanzania National Parks) ;
Horvath, Julie E. (University of North Carolina at Chapel Hill. Renaissance Computing Institute) ;
Hvilsom, Christina (Copenhagen Zoo) ;
Juan, David (Institut de Biologia Evolutiva (Barcelona)) ;
Frandsen, Peter (Copenhagen Zoo) ;
Schraiber, Joshua G. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
de Melo, Fabiano R. (Universidade Federal de Viçosa) ;
Bertuol, Fabrício (Universidade Federal do Amazonas. Departamento de Genética) ;
Byrne, Hazel (University of Utah. Department of Anthropology) ;
Sampaio, Iracilda (Universidade Federal do Pará (Brasil)) ;
Pires Farias, Izeni (Universidade Federal do Amazonas. Departamento de Genética) ;
Valsecchi, João (Comunidad de Manejo de Fauna Silvestre en la Amazonía y en Latinoamérica-ComFauna) ;
Messias, Malu (Universidade Federal de Rondônia) ;
da Silva, Maria N. F. (Instituto Nacional de Pesquisas da Amazônia) ;
Trivedi, Mihir (Centre for Cellular and Molecular Biology (Hyderabad, Índia)) ;
Rossi, Rogerio (Universidade Federal do Mato Grosso. Instituto de Biociências) ;
Hrbek, Tomas (Trinity University. Department of Biology) ;
Andriaholinirina, Nicole (University of Mahajanga. Faculty of Science, Technology and Environment) ;
Rabarivola, Clément J. (University of Mahajanga. Faculty of Science, Technology and Environment) ;
Zaramody, Alphonse (University of Mahajanga. Faculty of Science, Technology and Environment) ;
Jolly, Clifford J. (New York University .Department of Anthropology) ;
Phillips-Conroy, Jane (Washington University School of Medicine in St Louis. Department of Neuroscience) ;
Wilkerson, Gregory (MD Anderson Cancer Center. Keeling Center for Comparative Medicine and Research) ;
Abbee, C. (MD Anderson Cancer Center. Keeling Center for Comparative Medicine and Research) ;
Simmons, Joe H. (MD Anderson Cancer Center. Keeling Center for Comparative Medicine and Research) ;
Fernandez-Duque, Eduardo (Yale University. Department of Anthropology) ;
Kanthaswamy, Sree (University of California. California National Primate Research Center) ;
Shiferaw, Fekadu (The Carter Center Ethiopia) ;
Wu, Dong-Dong (Chinese Academy of Sciences. Kunming Institute of Zoology. State Key Laboratory of Genetic Resources and Evolution) ;
Zhou, Long (Zhejiang University School of Medicine. Center for Evolutionary and Organismal Biology) ;
Shao, Yong (Chinese Academy of Sciences. Kunming Institute of Zoology. State Key Laboratory of Genetic Resources and Evolution) ;
Zhang, Guojie (Zhejiang University Medical Center) ;
Keyyu, Julius D. (Tanzania Wildlife Research Institute) ;
Knauf, Sascha (Justus Liebig University. Faculty of Veterinary Medicine) ;
Le, Minh D. (Vietnam National University. Department of Environmental Ecology) ;
Lizano, Esther (Institut Català de Paleontologia Miquel Crusafont) ;
Merker, Stefan epartment of Environmental Ecology (State Museum of Natural History Stuttgart. Department of Zoology) ;
Navarro, Arcadi, 1969- (Institut de Biologia Evolutiva (Barcelona)) ;
Nadler, Tilo (Cuc Phuong Commune) ;
Khor, Chiea Chuen (Genome Institute of Singapore) ;
Lee, Jessica (Mandai Nature) ;
Tan, Patrick (Duke-NUS Medical School) ;
Lim, Weng Khong (SingHealth Duke-NUS Genomic Medicine Centre) ;
Kitchener, Andrew C. (School of Geosciences) ;
Zinner, Dietmar (Leibniz ScienceCampus Primate Cognition) ;
Gut, Ivo (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
Melin, Amanda D. (University of Calgary. Alberta Children's Hospital Research Institute) ;
Guschanski, Katerina (University of Edinburgh. School of Biological Sciences) ;
Schierup, Mikkel Heide (Aarhus University. Bioinformatics Research Centre) ;
Beck, Robin (University of Salford. School of Science, Engineering and Environment) ;
Karakikes, Ioannis (Stanford University. Department of Cardiothoracic Surgery) ;
Wang, Kevin C. (Veterans Affairs Palo Alto Healthcare System) ;
Umapathy, Govindhaswamy (Centre for Cellular and Molecular Biology (Hyderabad, Índia)) ;
Roos, Christian (Leibniz Institute for Primate Research. German Primate Center) ;
Boubli, Jean (University of Salford. School of Science, Engineering and Environment) ;
Siepel, Adam (Simons Center for Quantitative Biology. Cold Spring Harbor Laboratory) ;
Kundaje, Anshul (Stanford University. Department of Genetics) ;
Paten, Benedict (University of California. Santa Cruz Genomics Institute) ;
Lindblad-Toh, Kerstin (Uppsala University. Department of Medical Biochemistry and Microbiology) ;
Rogers, Jeffrey (Baylor College of Medicine. Department of Molecular and Human Genetics) ;
Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont) ;
Farh, Kyle Kai-How (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units))
Noncoding DNA is central to our understanding of human gene regulation and complex diseases and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in the human genome. [...]
2023 -  10.1038/s41586-023-06798-8
Nature, Published online nov. 2023
|
|
|
2.
|
|
8 p, 1.0 MB |
Expression Patterns of miR181a and miR30d in Patients with Breast Cancer
/
Tavakolpournegari, Alireza (Islamic Azad University) ;
Hashemi, Mehrdad (Islamic Azad University) ;
Zare Karizi, Shohreh (Islamic Azad University) ;
Matin Ahmadi, Arash (Nicolaus Copernicus University) ;
Bidooki, Seyed Hesamoddin (University of Zaragoza) ;
Banaei, Gooya (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
One of the important molecular pathways in breast cancer is the PTEN-PI3K-AKT pathway. Any change in the activity of the PTEN gene can alter the PI3K-AKT pathway. Moreover, there are subsets of genes and pathways their expression changes by post-transcriptional regulations. [...]
2022 - 10.18502/ijph.v51i7.10093
Iranian Journal of Public Health, Vol. 51, Num. 7 (July 2022) , p. 1594-1601
|
|
|
3.
|
|
25 p, 2.6 MB |
Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation
/
García-Padilla, Carlos (Universidad de Jaén) ;
Domínguez, Jorge N. (Universidad de Jaén) ;
Lodde, Valeria (University of Sassari. Department of Biomedical Sciences) ;
Munk, Rachel (Laboratory of Genetics and Genomics. National Institute on Aging IRP. National Institutes of Health) ;
Abdelmohsen, Kotb (Laboratory of Genetics and Genomics. National Institute on Aging IRP. National Institutes of Health) ;
Gorospe, Myriam (Laboratory of Genetics and Genomics. National Institute on Aging IRP. National Institutes of Health) ;
Jiménez-Sábado, Veronica (CIBERCV) ;
Ginel, Antonino (Institut d'Investigació Biomèdica Sant Pau) ;
Hove-Madsen, Leif (Institut d'Investigació Biomèdica Sant Pau) ;
Aránega, Amelia (Universidad de Jaén) ;
Franco, Diego (Universidad de Jaén)
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia in humans. Genetic and genomic analyses have recently demonstrated that the homeobox transcription factor Pitx2 plays a fundamental role regulating expression of distinct growth factors, microRNAs and ion channels leading to morphological and molecular alterations that promote the onset of AF. [...]
2022 - 10.1096/fj.202100844RR
FASEB Journal, Vol. 36 Núm. 1 (january 2022) , p. e22051
|
|
|
4.
|
|
17 p, 7.8 MB |
The ENA1 Na+-ATPase Gene Is Regulated by the SPS Sensing Pathway and the Stp1/Stp2 Transcription Factors
/
Zekhnini, Abdelghani (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Albacar, Marcel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Casamayor Gracia, Antonio (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
The Saccharomyces cerevisiae ENA1 gene, encoding a Na+-ATPase, responds transcriptionally to the alkalinization of the medium by means of a network of signals that involves the Rim101, the Snf1 and PKA kinases, and the calcineurin/Crz1 pathways. [...]
2023 - 10.3390/ijms24065548
International journal of molecular sciences, Vol. 24, Issue 6 (March 2023) , art. 5548
|
|
|
5.
|
|
30 p, 954.0 KB |
Circadian autonomy and rhythmic precision of the Arabidopsis female reproductive organ
/
Okada, Masaaki (Centre de Recerca en Agrigenòmica) ;
Yang, Zhiyuan (Centre de Recerca en Agrigenòmica) ;
Mas, Paloma (Centre de Recerca en Agrigenòmica)
The plant circadian clock regulates essential biological processes including flowering time or petal movement. However, little is known about how the clock functions in flowers. Here, we identified the circadian components and transcriptional networks contributing to the generation of rhythms in pistils, the female reproductive organ. [...]
2022 - 10.1016/j.devcel.2022.08.013
Developmental cell, Vol. 57, Issue 18 (September 2022) , p. 2168-2180
2 documents
|
|
|
6.
|
|
14 p, 5.6 MB |
SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade
/
Romero, Octavio A. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Vilarrubi, Andrea (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Alburquerque-Béjar, Juan Jos (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Gómez Moruno, Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Andrades, Álvaro (Universidad de Granada) ;
Trastulli, Deborah (Institut d'Investigació Biomèdica de Bellvitge) ;
Pros, Eva (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Setien, Fernando (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Verdura, Sara (Institut d'Investigació Biomèdica de Bellvitge) ;
Farre, Lourdes (Institut d'Investigació Biomèdica de Bellvitge) ;
Martín-Tejera, Juan F. (Institut d'Investigació Biomèdica de Bellvitge) ;
Llabata, Paula (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Oaknin, Ana (Hospital Universitari Vall d'Hebron) ;
Saigi, María (Institut Català d'Oncologia) ;
Piulats, Josep M. (Institut Català d'Oncologia) ;
Matias-Guiu, Xavier (Institut d'Investigació Biomèdica de Bellvitge) ;
Medina, Pedro P. (Universidad de Granada) ;
Vidal, August (Parc Científic de Barcelona) ;
Villanueva, Alberto (Parc Científic de Barcelona) ;
Sanchez-Cespedes, Montse (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Universitat Autònoma de Barcelona
Despite the genetic inactivation of SMARCA4, a core component of the SWI/SNF-complex commonly found in cancer, there are no therapies that effectively target SMARCA4-deficient tumours. Here, we show that, unlike the cells with activated MYC oncogene, cells with SMARCA4 inactivation are refractory to the histone deacetylase inhibitor, SAHA, leading to the aberrant accumulation of H3K27me3. [...]
2021 - 10.1038/s41467-021-24618-3
Nature communications, Vol. 12 Núm. 1 (january 2021) , p. 4319
|
|
|
7.
|
|
12 p, 1.8 MB |
Innovative Bioprocess Strategies Combining Physiological Control and Strain Engineering of Pichia pastoris to Improve Recombinant Protein Production
/
Gasset Franch, Arnau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ;
Garcia-Ortega, Xavier (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ;
Garrigos, Javier (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ;
Valero Barranco, Francisco (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ;
Montesinos Seguí, José Luis (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
The combination of strain and bioprocess engineering strategies should be considered to obtain the highest levels of recombinant protein production (RPP) while assuring product quality and process reproducibility of heterologous products. [...]
2022 - 10.3389/fbioe.2022.818434
Frontiers in Bioengineering and Biotechnology, Vol. 10 (January 2022) , art. 818434
|
|
|
8.
|
|
14 p, 1.5 MB |
Multiple Layered Control of the Conjugation Process of the Bacillus subtilis Plasmid pLS20
/
Meijer, Wilfried J. J. (Centro de Biología Molecular Severo Ochoa) ;
Boer, Roeland (ALBA Laboratori de Llum de Sincrotró) ;
Ares, Saúl (Centro Nacional de Biotecnología. Departamento de Biología de Sistemas) ;
Alfonso, Carlos (Centro de Investigaciones Biológicas (Madrid)) ;
Rojo, Fernando (Centro Nacional de Biotecnología. Department of Microbial Biotechnology) ;
Luque-Ortega, Juan Román (Centro de Investigaciones Biológicas (Madrid)) ;
Wu, Ling Juan (Newcastle University. Centre for Bacterial Cell Biology, Biosciences Institute)
Bacterial conjugation is the main horizontal gene transfer route responsible for the spread of antibiotic resistance, virulence and toxin genes. During conjugation, DNA is transferred from a donor to a recipient cell via a sophisticated channel connecting the two cells. [...]
2021 - 10.3389/fmolb.2021.648468
Frontiers in Molecular Biosciences, Vol. 8 (March 2021) , art. 648468
|
|
|
9.
|
|
11 p, 3.4 MB |
Identification of key sequence features required for microRNA biogenesis in plants
/
Rojas, Arantxa M. L. (Instituto de Biología Molecular y Celular de Rosario) ;
Drusin, Salvador I. (Instituto de Biología Molecular y Celular de Rosario) ;
Chorostecki, Uciel Pablo (Institut de Recerca Biomèdica) ;
Mateos, Julieta Lisa (Instituto de Fisiología, Biología Molecular y Neurociencias) ;
Moro, Belen (Centre de Recerca en Agrigenòmica) ;
Bologna, Nicolás (Centre de Recerca en Agrigenòmica) ;
Bresso, Edgardo G. (Instituto de Biología Molecular y Celular de Rosario) ;
Schapire, Arnaldo (Instituto de Biología Molecular y Celular de Rosario) ;
Rasia, Rodolfo (Instituto de Biología Molecular y Celular de Rosario) ;
Moreno, Diego M. (Universidad Nacional de Rosario. Departamento de Química-Física) ;
Palatnik, Javier (Instituto de Biología Molecular y Celular de Rosario)
MicroRNAs (miRNAs) are endogenous small RNAs of ∼21 nt that regulate multiple biological pathways in multicellular organisms. They derive from longer transcripts that harbor an imperfect stem-loop structure. [...]
2020 - 10.1038/s41467-020-19129-6
Nature communications, Vol. 11 (October 2020) , art. 5320
|
|
|
10.
|
|
visitant ::
identificació
alerta personal via correu electrònic o subscribiu-vos al 
canal RSS.
