Results overview: Found 20 records in 0.02 seconds.
Articles, 16 records found
Research literature, 4 records found
Articles 16 records found  1 - 10next  jump to record:
1.
2 p, 318.1 KB Dendritic cells from paediatric patients with type 1 diabetes show altered phagocytosis capacity correlating with disease evolution / Rodríguez-Fernández, Silvia (Institut Germans Trias i Pujol) ; Murillo, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Perna-Barrull, David (Institut Germans Trias i Pujol) ; Villalba Felipe, Adrián (Institut Germans Trias i Pujol) ; Maspoch, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Bel, Joan (Hospital Universitari Germans Trias i Pujol. Servei de Pediatria) ; Vives-Pi, Marta (Institut Germans Trias i Pujol)
Autoimmunity against β-cells in type 1 diabetes (T1D) is prompted by defective immunological tolerance, an event in which dendritic cells (DCs) play a crucial role as orchestrators of the immune response. [...]
2019 - 10.1007/s00125-019-4946-6
Diabetologia, Vol. 62, supl. 1 (Set. 2019) , art. S224  
2.
12 p, 1.1 MB Utility of insulin resistance in estimating cardiovascular risk in subjects with type 1 diabetes according to the scores of the Steno Type 1 / Cano, Albert (Universitat Autònoma de Barcelona. Departament de Medicina) ; Mazarico, Isabel (Universitat Autònoma de Barcelona. Departament de Medicina) ; Astiarraga, Brenno (Hospital Universitari Joan XXIII de Tarragona. Department of Endocrinology and Nutrition) ; González-Sastre, Montserrat (Universitat Autònoma de Barcelona. Departament de Cirurgia) ; Martínez, Laia (Hospital Universitari Joan XXIII de Tarragona. Departament d'Endocrinologia i Nutrició) ; Fernández-Veledo, Sonia (Hospital Universitari Joan XXIII de Tarragona. Departament d'Endocrinologia i Nutrició) ; Simó, Rafael (Universitat Autònoma de Barcelona. Departament de Medicina) ; Vendrell, Joan (Hospital Universitari de Tarragona Joan XXIII. Departament d'Endocrinologia i Nutrició) ; González-Clemente, José Miguel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Llauradó Cabot, Gemma (Universitat Autònoma de Barcelona. Departament d'Endocrinologia i Nutrició) ; Fàbregas, Lara Albert (Universitat Autònoma de Barcelona. Departament de Medicina)
Background: We sought to assess the potential of insulin resistance (IR) for estimating cardiovascular disease (CVD) risk in adults with type 1 diabetes (T1DM) according to the scores of the Steno Type 1 Risk Engine (ST1RE). [...]
2020 - 10.3390/jcm9072192
Journal of clinical medicine, Vol. 9 Núm. 7 (2020) , p. 2192  
3.
5 p, 396.1 KB Increased plasma neurofilament light chain levels in patients with type-1 diabetes with impaired awareness of hypoglycemia / Sampedro, Frederic (Institut d'Investigació Biomèdica Sant Pau) ; Stantonyonge, Nicole (Institut d'Investigació Biomèdica Sant Pau) ; Martínez-Horta, Saül (Institut d'Investigació Biomèdica Sant Pau) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Muñoz, Laia (Institut d'Investigació Biomèdica Sant Pau) ; Pérez-González, Rocío (Institut d'Investigació Biomèdica Sant Pau) ; Marín-Lahoz, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Gómez Ansón, Beatriz (Institut d'Investigació Biomèdica Sant Pau) ; Chico, Ana (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Impaired awareness of hypoglycemia (IAH) is a common complication in patients with type-1 diabetes (T1D). IAH is a major risk factor for severe hypoglycemic events, leading to adverse clinical consequences and cerebral damage. [...]
2020 - 10.1136/bmjdrc-2020-001516
BMJ open diabetes research and care, Vol. 8 (july 2020)  
4.
13 p, 1.5 MB Impaired Phagocytosis in Dendritic Cells From Pediatric Patients With Type 1 Diabetes Does Not Hamper Their Tolerogenic Potential / Rodríguez Fernández, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Murillo, Marta (Hospital Universitari Germans Trias i Pujol) ; Villalba Felipe, Adrián (Hospital Universitari Germans Trias i Pujol) ; Perna Barrull, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cano-Sarabia, Mary (Institut Català de Nanociència i Nanotecnologia) ; Gómez Muñoz, Laia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Aguilera, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Vázquez, Federico (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bel, Joan (Hospital Universitari Germans Trias i Pujol) ; Vives Pi, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Type 1 diabetes (T1D) is prompted by defective immunological tolerance, an event in which dendritic cells (DCs) are crucial as immune response orchestrators. In fact, they contribute to maintaining tolerance to self-antigens, but they can also prompt an immunogenic response against them, leading to autoimmunity. [...]
2019 - 10.3389/fimmu.2019.02811
Frontiers in immunology, Vol. 10 (November 2019) , art. 2811  
5.
17 p, 1.9 MB Specific nuclear magnetic resonance lipoprotein subclass profiles and central arterial stiffness in type 1 diabetes mellitus : a case control study / Llauradó Cabot, Gemma (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas) ; Amigó, Núria (Universitat Rovira i Virgili) ; Cano, Albert (Department of Endocrinology and Nutrition. Hospital de Sabadel) ; Ballesta, Silvia (Department of Endocrinology and Nutrition, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Universitat Autònoma de Barcelona) ; Lara, Albert (Department of Endocrinology and Nutrition. Hospital de Sabadell) ; Mazarico, Isabel (Department of Endocrinology and Nutrition. Hospital de Sabadell) ; Fernández Veledo, Sonia (Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili) ; Pedro-Botet, Juan (Universitat Autònoma de Barcelona. Departament de Medicina) ; Vendrell, Joan (Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili) ; González Clemente, José Miguel (Department of Endocrinology and Nutrition. Hospital de Sabadell)
Background: Dyslipidemia has been associated with vascular complications of type 1 diabetes mellitus (T1DM). We examined the proton nuclear magnetic resonance (NMR)-assessed lipoprotein subclass profilesin subjectswith T1DM comparedwith those of healthy subjects and assessed the potential relationship of these profiles with arterial stiffness. [...]
2019 - 10.3390/jcm8111875
Journal of clinical medicine, Vol. 9 (2019) , p. 1-17  
6.
15 p, 5.9 MB Prenatal administration of Betamethasone causes changes in the T cell receptor repertoire influencing Development of autoimmunity / Gieras, Anna (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Gehbauer, Christina (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Perna Barrull, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Engler, Jan Broder (Institute of Neuroimmunology and Multiple Sclerosis. Center for Molecular Neurobiology Hamburg) ; Diepenbruck, Ines (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Glau, Laura (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Joosse, Simon A. (University Medical Center Hamburg-Eppendorf. Department of Tumor Biology) ; Kersten, Nora (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Klinge, Stefanie (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Mittrücker, Hans-Willi (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Friese, Manuel A. (Institute of Neuroimmunology and Multiple Sclerosis, Center for Molecular Neurobiology Hamburg) ; Vives-Pi, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Tolosa, Eva (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Universitat Autònoma de Barcelona
Prenatal glucocorticoids are routinely administered to pregnant women at risk of preterm delivery in order to improve survival of the newborn. However, in half of the cases, birth occurs outside the beneficial period for lung development. [...]
2017 - 10.3389/fimmu.2017.01505
Frontiers in immunology, Vol. 8 (november 2017) , p. 1-15  
7.
14 p, 538.5 KB ViDa1: The Development and Validation of a New Questionnaire for Measuring Health-Related Quality of Life in Patients with Type 1 Diabetes / Alvarado-Martel, Dácil (Complejo Hospitalario Univesitario Insular Materno-Infantil de Gran Canaria) ; Ruiz Fernández, M. Angeles (Universidad Nacional de Educación a Distancia, Madrid) ; Cuadrado Vigaray, Maribel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Carrillo, Armando (Complejo Hospitalario Univesitario Insular Materno-Infantil de Gran Canaria) ; Boronat, Mauro (Complejo Hospitalario Univesitario Insular Materno-Infantil de Gran Canaria) ; Montesdeoca, Ana Expósito (Instituto Universitario de Investigaciones Biomédicas y Sanitarias. Universidad de Las Palmas de Gran Canaria) ; Nattero Chávez, Lía (Hospital Universitario Ramón y Cajal) ; Pozuelo Sánchez, Maite (Hospital Universitario Ramón y Cajal) ; López Quevedo, Pino (Hospital Universitario de Gran Canaria Doctor Negrín) ; Santana Suárez, Ana D. (Hospital Universitario de Gran Canaria Doctor Negrín) ; Hillman, Natalia (Hospital Universitario La Paz) ; Subias, David (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Martin Vaquero, Pilar (D-Médical Clinic, Madrid) ; Sáez de Ibarra, Lourdes (Hospital Universitario La Paz) ; Mauricio Puente, Dídac (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; de Pablos Velasco, Pedro (Instituto Universitario de Investigaciones Biomédicas y Sanitarias. Universidad de Las Palmas de Gran Canaria) ; Nóvoa, Francisco J. (Complejo Hospitalario Univesitario Insular Materno-Infantil de Gran Canaria) ; Wägner, Ana M. (Complejo Hospitalario Univesitario Insular Materno-Infantil de Gran Canaria) ; Universitat Autònoma de Barcelona
This study describes the development of a new questionnaire to measure health-related quality of life (HRQoL) in patients with type 1 diabetes (the ViDa1 questionnaire) and provides information on its psychometric properties. [...]
2017 - 10.3389/fpsyg.2017.00904
Frontiers in psychology, Vol. 8 Núm. 904 (2017) , p. 1-14  
8.
9 p, 859.1 KB Preclinical carotid atherosclerosis in patients with latent autoimmune diabetes in adults (LADA), type 2 diabetes and classical type 1 diabetes / Hernández, Marta (Hospital Universitari Arnau de Vilanova) ; López, Carolina (Universitat de Lleida. Escola d'Infermeria) ; Real, Jordi (Epidemiologia i Salut Pública, Universitat International de Catalunya) ; Valls, Joan (Institut de Recerca Biomèdica de Lleida) ; Ortega Martinez de Victoria, Emilio (Hospital Clínic. Departament d'Endocrinologia i Nutrició) ; Vázquez, Federico (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rubinat, Esther (Universitat de Lleida. Escola d'Infermeria) ; Granado Casas, Minerva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Alonso Pedrol, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Molí, Teresa (Hospital Universitari Arnau de Vilanova) ; Betriu, Angels (Institut de Recerca Biomèdica de Lleida) ; Lecube, Albert (Hospital Universitari Arnau de Vilanova) ; Fernández, Elvira (Hospital Universitari Arnau de Vilanova) ; Leslie, Richard David (The Blizard Institute, Barts and the London School of Medicine and Dentistry, London) ; Mauricio, Dídac (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Background: LADA is probably the most prevalent form of autoimmune diabetes. Nevertheless, there are few data about cardiovascular disease in this group of patients. The aim of this study was to investigate the frequency of carotid atherosclerotic plaques in patients with LADA as compared with patients with classic type 1 diabetes and type 2 diabetes. [...]
2017 - 10.1186/s12933-017-0576-9
Cardiovascular Diabetology, Vol. 16 Núm. 94 (2017) , p. 1-9  
9.
8 p, 1.1 MB Consistent findings in glycaemic control, body weight and hypoglycaemia with iGlarLixi (insulin glargine/lixisenatide titratable fixed-ratio combination) vs insulin glargine across baseline HbA1c, BMI and diabetes duration categories in the LixiLan-L trial / Wysham, Carol (Rockwood Clinic, Spokane, Washington) ; Bonadonna, Riccardo C. (, Department of Clinical and Experimental Medicine, University of Parma) ; Aroda, Vanita R. (Medstar Health Research Institute, Hyattsville, Maryland) ; Puig Domingo, Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Kapitza,Christoph (Profil Institute, Neuss, Germany) ; Stager, William (Sanofi, Bridgewater, New Jersey) ; Yu, Christine (Sanofi, Bridgewater, New Jersey) ; Niemoeller, Elisabeth (Sanofi, Frankfurt, Germany) ; Souhami, Elisabeth (Sanofi, Paris, France) ; Bergenstal,Richard M. (International Diabetes Center, Park Nicollet Health Services, Minneapolis, Minnesota) ; Universitat Autònoma de Barcelona
Aims: To assess the impact of baseline characteristics on clinical outcomes in the LixiLan-L trial, a randomized open-label trial designed to evaluate the efficacy and safety of iGlarLixi, a novel fixed-ratio combination of insulin glargine 100 U (iGlar) plus lixisenatide, in comparison with iGlar over 30 weeks in a population of patients with type 2 diabetes mellitus (T2DM) inadequately controlled on a previous regimen of basal insulin alone or in combination with 1 or 2 oral glucose-lowering drugs. [...]
2017 - 10.1111/dom.12961
Diabetes, Obesity and Metabolism, Vol. 19 (2017) , p. 1408-1415  
10.
17 p, 2.4 MB Phosphatidylserine-liposomes promote tolerogenic features on dendritic cells in human type 1 diabetes by apoptotic mimicry / Rodriguez Fernandez, Silvia (Institut Germans Trias i Pujol) ; Pujol Autonell, Irma (Institut Germans Trias i Pujol) ; Brianso, Ferran (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Perna Barrull, David (Institut Germans Trias i Pujol) ; Cano-Sarabia, Mary (Institut Català de Nanociència i Nanotecnologia) ; García Jimeno, Sonia (Institut Català de Nanociència i Nanotecnologia) ; Villalba Felipe, Adrián (Institut Germans Trias i Pujol) ; Sanchez, Alex (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Aguilera, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Vazquez, Federico (Hospital Universitari Germans Trias i Pujol. Servei d'Endocrinologia) ; Verdaguer, Joan (Universitat de Lleida. Departament de Medicina Experimental) ; Maspoch Comamala, Daniel (Institució Catalana de Recerca i Estudis Avançats) ; Vives-Pi, Marta (Institut Germans Trias i Pujol)
Type 1 diabetes (T1D) is a metabolic disease caused by the autoimmune destruction of insulin-producing β-cells. With its incidence increasing worldwide, to find a safe approach to permanently cease autoimmunity and allow β-cell recovery has become vital. [...]
2018 - 10.3389/fimmu.2018.00253
Frontiers in immunology, Vol. 9 (Feb. 2018) , art. 253  

Articles : 16 records found   1 - 10next  jump to record:
Research literature 4 records found  
1.
1 p, 751.8 KB Type 1 diabetes mellitus immunotherapy : using regulatory T cells to balance the immune response / Crespo Galván, Raquel ; Álvarez, Iñaki, dir., (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2017
Grau en Microbiologia [816]  
2.
1 p, 491.8 KB Proposal of a research project : use mesenchymal stem cell derived exosomes targeted to T cells and charged with specific miRNA as a therapeutic tool against type 1 diabetes / Vicente Rizo, Sílvia ; Roher Armentia, Nerea (Universitat Autònoma de Barcelona. Departament de Biologia, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Bioquímica [814]  
3.
1 p, 1.7 MB Shifting central tolerance in type 1 diabetes : tolerance induction by presenting peptides in non-obese diabetic mice / Garnica Caparrós, Josep ; Álvarez, Iñaki, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Ciències Biomèdiques [832]  
4.
1 p, 1.0 MB Gen therapy for diabetes type 1 / Sánchez Hidalgo, Rebeca ; Villaverde Corrales, Antonio, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Microbiologia [816]  

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