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7 p, 480.5 KB |
Cord Blood Units with High CD3+ Cell Counts Predict Early Lymphocyte Recovery After In Vivo T Cell-Depleted Single Cord Blood Transplantation
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Castillo, N. (Banc de Sang i Teixits) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Díaz de Heredia, Cristina (Hospital Universitari Vall d'Hebron) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Barba, Pere (Hospital Universitari Vall d'Hebron) ;
Ferrá, Christelle (Institut Català d'Oncologia) ;
Canals, Carme (Banc de Sang i Teixits) ;
Elorza, Izaskun (Hospital Universitari Vall d'Hebron) ;
Olivé, Teresa (Hospital Universitari Vall d'Hebron) ;
Badell Serra, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Valcárcel, David (Hospital Universitari Vall d'Hebron) ;
Querol, Sergio (Banc de Sang i Teixits) ;
Universitat Autònoma de Barcelona
Although high absolute lymphocyte count (ALC) early after transplantation is a simple surrogate for immune reconstitution, few studies to date have established the predictive factors for ALC after umbilical cord blood transplantation (UCBT). [...]
2016 -  10.1016/j.bbmt.2016.03.009
Biology of blood and marrow transplantation, Vol. 22 Núm. 6 (january 2016) , p. 1073-1079
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7 p, 732.4 KB |
Early and Long-Term Impaired T Lymphocyte Immune Reconstitution after Cord Blood Transplantation with Antithymocyte Globulin
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Castillo, Nerea (Banc de Sang i Teixits) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Barba, Pere (Hospital Universitari Vall d'Hebron) ;
Canals, Carme (Banc de Sang i Teixits) ;
Díaz de Heredia, Cristina (Hospital Universitari Vall d'Hebron) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Ferrá, Christelle (Institut Català d'Oncologia) ;
Badell Serra, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Elorza, Izaskun (Hospital Universitari Vall d'Hebron) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Valcárcel, David (Hospital Universitari Vall d'Hebron) ;
Querol, Sergio (Banc de Sang i Teixits) ;
Universitat Autònoma de Barcelona
Immune reconstitution is crucial to the success of allogeneic hematopoietic stem cell transplantation. Umbilical cord blood transplantation (UCBT) has been associated with delayed immune reconstitution. [...]
2017 - 10.1016/j.bbmt.2016.11.014
Biology of blood and marrow transplantation, Vol. 23 Núm. 3 (january 2017) , p. 491-497
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10 p, 786.4 KB |
Haploidentical transplantation is associated with better overall survival when compared to single cord blood transplantation : An EBMT-Eurocord study of acute leukemia patients conditioned with thiotepa, busulfan, and fludarabine
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Giannotti, Federica (Saint-Antoine Hospital) ;
Labopin, Myriam (Hôpital Saint-Antoine (Paris, França)) ;
Shouval, Roni (Chaim Sheba Medical Center (Israel)) ;
Sanz, Jaime (Instituto de Salud Carlos III) ;
Arcese, William (Rome Transplant Network tor Vergatä) ;
Angelucci, Emanuele (Ospedale Policlinico San Martino) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Ribera, Jose-Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Santarone, Stella (Ospedale Civile) ;
Benedetto, Bruno (S.S.C.V.D Trapianto di Cellule Staminali A.O.U Citta della Salute e della Scienza di Torino) ;
Rambaldi, Alessandro (Azienda Ospedaliera Papa Giovanni XXIII) ;
Saccardi, Riccardo (Azienda Ospedaliera Universitaria Careggi) ;
Blaise, Didier (Institut Paoli Calmettes) ;
Carella, Michele Angelo (IRCCS) ;
Rocha, Vanderson (Universidade de São Paulo) ;
Baron, Frederic (University of Liege) ;
Mohty, Mohamad (Hospital Saint- Antoine) ;
Ruggeri, Annalisa (Ospedale Pediatrico Bambino Gesù (Roma, Itàlia)) ;
Nagler, Arnon (Tel-Aviv University) ;
Universitat Autònoma de Barcelona
Thiotepa-busulfan-fludarabine (TBF) is a widely used conditioning regimen in single umbilical cord blood transplantation (SUCBT). More recently, it was introduced in the setting of non-T cell depleted haploidentical stem cell transplantation (NTD-Haplo). [...]
2018 - 10.1186/s13045-018-0655-8
Journal of hematology & oncology, Vol. 11 Núm. 1 (30 2018) , p. 110
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6 p, 657.1 KB |
Outcomes of Advanced Hodgkin Lymphoma after Umbilical Cord Blood Transplantation : A Eurocord and EBMT Lymphoma and Cellular Therapy & Immunobiology Working Party Study
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Paviglianiti, Annalisa (Centre Scientifique de Monaco) ;
Tozatto Maio, Karina (Centre Scientifique de Monaco) ;
Rocha, Vanderson (Hospital Sao Paulo) ;
Gehlkopf, Eve (CHU Lapeyronie) ;
Milpied, Noel (CHU Bordeaux) ;
Esquirol, Albert (Institut d'Investigació Biomèdica Sant Pau) ;
Chevallier, Patrice (Hospital Hotel Dieu (Nantes, França)) ;
Blaise, Didier (Institute Paoli Calmettes) ;
Gac, Anne-Claire (Institut d'Hématologie de Basse-Normandie) ;
Leblond, Véronique (Hopital la Pitié-Salpêtrière) ;
Cahn, Jean-Yves (CHU Grenoble Alpes) ;
Abecasis, Manuel (Institute Portugues Oncologia) ;
Zuckerman, Tsila (Rambam Medical Center) ;
Schouten, Harry (University Hospital Maastricht) ;
Gurman, Gunhan (Ankara University) ;
Rubio, Marie Thérèse (Hôpitaux des Brabois) ;
Beguin, Yves (CHU of Liège and University of Liege) ;
Corral, Lucia Lopez (Centro de Investigacion del Cancer-IBMCC) ;
Nagler, Amon (Chaim Sheba Medical Center (Israel)) ;
Snowden, John A. (Sheffield Teaching Hospitals NHS Trust) ;
Koc, Yener (Stem Cell Transplant Unit Medical Park Hospitals) ;
Mordini, Nicola (Az. Ospedaliera S. Croce e Carle) ;
Bonifazi, Francesca ("Seragnoli" University Hospital S. Orsola-Malpighi) ;
Volt, Fernanda (Centre Scientifique de Monaco) ;
Kenzey, Chantal (Centre Scientifique de Monaco) ;
Robinson, Stephen Paul (EBMT Lymphoma Working Party) ;
Montoto, Silvia (EBMT Lymphoma Working Party) ;
Gluckman, Eliane (Centre Scientifique de Monaco) ;
Ruggeri, Annalisa (Bambin Gesù) ;
Universitat Autònoma de Barcelona
Allogeneic stem cell transplantation is an alternative for patients with relapsed or refractory Hodgkin lymphoma (HL), but only limited data on unrelated umbilical cord blood transplantation (UCBT) are available. [...]
2018 - 10.1016/j.bbmt.2018.07.019
Biology of blood and marrow transplantation, Vol. 24 Núm. 11 (november 2018) , p. 2265-2270
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7 p, 530.8 KB |
Reduced-Intensity versus Myeloablative Conditioning in Cord Blood Transplantation for Acute Myeloid Leukemia (40-60 years) across Highly Mismatched HLA Barriers-On Behalf of Eurocord and the Cellular Therapy & Immunobiology Working Party (CTIWP) of EBMT
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Sheth, Vipul (Fred Hutchison Cancer Research Centre) ;
Volt, Fernanda (Eurocord) ;
Sanz, Jaime (Hospital Universitari i Politècnic La Fe (València)) ;
Clement, Laurence (Haut-Lévêque) ;
Cornelissen, Jan (Erasmus MC-Daniel den Hoed Cancer Centre) ;
Blaise, Didier (Paoli Calmettes) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Michallet, Mauricette (Centre Leon Berard) ;
Saccardi, Riccardo (Careggi University Hospital (Florència, Itàlia)) ;
Rocha, Vanderson (Eurocord) ;
Gluckman, Eliane (Eurocord) ;
Chabannon, Christian (Institut Paoli-Calmettes) ;
Ruggeri, Annalisa (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Universitat Autònoma de Barcelona
The use of myeloablative conditioning (MAC) in umbilical cord blood transplantation (UCBT) has been associated with high nonrelapse mortality (NRM) in patients aged >40 years, especially those having a high HLA disparity, thus limiting wider applications. [...]
2020 - 10.1016/j.bbmt.2020.07.025
Biology of blood and marrow transplantation, Vol. 26 Núm. 11 (november 2020) , p. 2098-2104
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11 p, 682.2 KB |
Mesenchymal stem cells for cardiac repair : are the actors ready for the clinical scenario?
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Roura, Santiago (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mirabel, Clémentine (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vives Armengol, Joaquim (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
For years, sufficient progress has been made in treating heart failure following myocardial infarction; however, the social and economic burdens and the costs to world health systems remain high. Moreover, treatment advances have not resolved the underlying problem of functional heart tissue loss. [...]
2017 - 10.1186/s13287-017-0695-y
Stem cell research & therapy, Vol. 8 (october 2017)
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15 p, 2.3 MB |
Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine
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Monguió Tortajada, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rudilla, F. (Institut Germans Trias i Pujol) ;
Gálvez-Montón, Carolina (Institut Germans Trias i Pujol) ;
Pujal, Josep Maria (Universitat de Girona. Laboratori de processament cel·lular) ;
Aran, Gemma (Institut Germans Trias i Pujol) ;
Sanjurjo, Lucía (Institut Germans Trias i Pujol) ;
Franquesa, Marcella (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sarrias, Maria-Rosa (Institut Germans Trias i Pujol) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Borràs i Serres, Francesc Enric (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Undesired immune responses have drastically hampered outcomes after allogeneic organ transplantation and cell therapy, and also lead to inflammatory diseases and autoimmunity. Umbilical cord mesenchymal stem cells (UCMSCs) have powerful regenerative and immunomodulatory potential, and their secreted extracellular vesicles (EVs) are envisaged as a promising natural source of nanoparticles to increase outcomes in organ transplantation and control inflammatory diseases. [...]
2017 - 10.7150/thno.16154
Theranostics, Vol. 7 Núm. 2 (2017) , p. 270-284
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20 p, 183.8 KB |
A vida como biocapital - futuros biológicos, uma aposta dos bancos privados de células-tronco de cordão umbilical no Brasil
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Galindo, Dolores (Universidade Federal de Mato Grosso) ;
Silveira Lemos, Flávia (Universidade Federal do Paraná) ;
Vilela Rodrigues, Renata (Universidade Federal de Mato Grosso)
Com o desenvolvimento da biotecnomedicina contemporânea aliada ao neoliberalismo, a saúde e a vida são entrelaçadas a um emergente mercado de biocapitais. Nas camadas médias brasileiras, ao lado das preconizadas preocupações com a saúde do recém-nascido, busca-se, também, garantir o futuro por meio da contratação de biobancos privados especializados na coleta e armazenamento de célulastronco do cordão umbilical e tecido placentário. [...]
With the development of contemporary medical biotechnology, health and life are intertwined in a market of care by fear, anticipation, and promotion, only a posteriori in the form of treatments. A posture of fear and persecution, to ensure the future health of the child is not only to provide medical monitoring, because in wait there might exist diseases that were not even named and engendered. [...]
2014 - 10.5565/rev/athenea.1198
Athenea digital : revista de pensamiento e investigación social, Vol. 14 Núm. 2 (julio 2014) , p. 255-274
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