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13 p, 1.4 MB |
Evaluation of the Kinetics of Pancreatic Stone Protein as a Predictor of Ventilator-Associated Pneumonia
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Ceccato, Adrian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Camprubí-Rimblas, Marta (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Bos, Lieuwe D (University of Amsterdam) ;
Povoa, Pedro (OUH Odense University Hospital) ;
Martin-Loeches, Ignacio (Hospital Clínic i Provincial de Barcelona) ;
Forné, Carles (Universitat de Lleida) ;
Areny-Balagueró, Aina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Campaña-Duel, Elena (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Morales-Quinteros, Luis (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Quero, Sara (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Ramirez, Paula (Hospital Universitari i Politècnic La Fe (València)) ;
Esperatti, Mariano (Hospital Privado de Comunidad) ;
Torres, Antoni (Hospital Clínic i Provincial de Barcelona) ;
Blanch, Lluís (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Universitat Autònoma de Barcelona
Ventilator-associated pneumonia (VAP) is a severe condition. Early and adequate antibiotic treatment is the most important strategy for improving prognosis. Pancreatic Stone Protein (PSP) has been described as a biomarker that increases values 3-4 days before the clinical diagnosis of nosocomial sepsis in different clinical settings. [...]
2023 -  10.3390/biomedicines11102676
Biomedicines, Vol. 11 (september 2023)
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2.
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12 p, 1.4 MB |
Composition and diversity analysis of the lung microbiome in patients with suspected ventilator-associated pneumonia
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Fenn, Dominic (University of Manchester) ;
Abdel-Aziz, Mahmoud I. (University of Manchester) ;
van Oort, Pouline M. P. (University of Manchester) ;
Brinkman, Paul (University of Manchester) ;
Ahmed, Waqar M. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Felton, Timothy (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Póvoa, Pedro (New University of Lisbon) ;
Martin-Loeches, Ignacio (St. James's Hospital ( Dublín, Irlanda)) ;
Schultz, Marcus J. (Amsterdam UMC Location University of Amsterdam) ;
Dark, Paul (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Fowler, Stephen J. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Bos, Lieuwe D (Amsterdam UMC Location University of Amsterdam) ;
Universitat Autònoma de Barcelona
Ventilator-associated pneumonia (VAP) is associated with high morbidity and health care costs, yet diagnosis remains a challenge. Analysis of airway microbiota by amplicon sequencing provides a possible solution, as pneumonia is characterised by a disruption of the microbiome. [...]
2022 - 10.1186/s13054-022-04068-z
Critical Care, Vol. 26 (july 2022)
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3.
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14 p, 1.9 MB |
Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients : a randomised controlled trial
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Chastre, Jean (Service de Médecine Intensive Réanimation. Institut de Cardiologie. Groupe Hospitalier Pitié-Salpêtrière. Assistance Publique-Hôpitaux de Paris. Sorbonne University) ;
François, Bruno (Réanimation Polyvalente and Inserm CIC 1435 & UMR 1092. CHU) ;
Bourgeois, Marc (AZ Sint-Jan Brugge-Oostende AV) ;
Komnos, Apostolos (General Hospital of Larissa) ;
Ferrer, Ricard (Hospital Universitari Vall d'Hebron) ;
Rahav, Galia (Chaim Sheba Medical Center. Sackler School of Medicine. Tel Aviv University) ;
De Schryver, Nicolas (Clinique Saint-Pierre) ;
Lepape, Alain (Hospices Civils de Lyon Hôpital Lyon Sud) ;
Koksal, Iftihar (Faculty of Medicine. Trabzon and Acibadem University Faculty of Medicine. Karadeniz Technical University) ;
Luyt, Charles-Edouard (Service de Médecine Intensive Réanimation. Institut de Cardiologie. Groupe Hospitalier Pitié-Salpêtrière. Assistance Publique-Hôpitaux de Paris. Sorbonne University) ;
Sánchez-García, Miguel (Hospital Clínico San Carlos. Unidad de Cuidados Intensivos) ;
Torres, Antoni (Hospital Clínic i Provincial de Barcelona. Servei de Pneumologia) ;
Eggimann, Philippe (Department of Locomotor Apparatus. Centre Hospitalier Universitaire Vaudois CHUV) ;
Koulenti, Despoina (2nd Critical Care Department. Attikon University Hospital. National and Kapodistrian. University of Athens) ;
Holland, Thomas L. (Duke Clinical Research Institute) ;
Ali, Omar (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Shoemaker, Kathryn (Respiratory and Immunology. BioPharmaceuticals R&D. AstraZeneca) ;
Ren, Pin (Respiratory and Immunology. BioPharmaceuticals R&D. AstraZeneca) ;
Sauser, Julien (Infection Control Program. Faculty of Medicine. Geneva University Hospitals) ;
Ruzin, Alexey (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Tabor, David E. (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Akhgar, Ahmad (Clinical Pharmacology and Quantitative Pharmacology. Clinical Pharmacology and Safety Sciences. BioPharmaceuticals R&D. AstraZeneca) ;
Wu, Yuling (Clinical Pharmacology and Quantitative Pharmacology. Clinical Pharmacology and Safety Sciences. BioPharmaceuticals R&D. AstraZeneca) ;
Jiang, Yu (Clinical Pharmacology and Quantitative Pharmacology. Clinical Pharmacology and Safety Sciences. BioPharmaceuticals R&D. AstraZeneca) ;
DiGiandomenico, Antonio (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Colbert, Susan (Oncology. US SM&M. AstraZeneca) ;
Vandamme, Drieke (Inserm CIC 1435. CHU) ;
Coenjaerts, Frank (University Medical Center Utrecht) ;
Malhotra-Kumar, Surbhi (University of Antwerp. Laboratory of Medical Microbiology) ;
Timbermont, Leen (University of Antwerp. Laboratory of Medical Microbiology) ;
Oliver, Antonio (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Barraud, Olivier (INSERM U1092. Centre Hospitalier Universitaire de Limoges. Université Limoges) ;
Bellamy, Terramika (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Bonten, Marc (Julius Center for Health Science and Primary Care. University Medical Center Utrecht. Utrecht University) ;
Goossens, Herman (Laboratory of Medical Microbiology. Vaccine and Infectious Disease Institute. University of Antwerp) ;
Reisner, Colin (DevPro Biopharma) ;
Esser, Mark T. (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Jafri, Hasan S. (Late-Stage Development. Respiratory and Immunology. BioPharmaceuticals R&D. AstraZeneca) ;
Joannidis, Michael ;
Klimscha, Walter ;
De Waele, Elisabeth ;
Devriendt, Jacques ;
Huberlant, Vincent ;
Depuydt, Pieter ;
Van Boxstael, Sam ;
Peric, Mladen ;
Kopic, Jasminka ;
Hanauer, Michal ;
Hruby, Tomas ;
Sramek, Vladimir ;
Svoboda, Petr ;
Vymazal, Tomas ;
Novacek, Martin ;
Annane, Djillali ;
Mira, Jean-Paul ;
Souweine, Bertrand ;
Dequin, Pierre-François ;
Meziani, Ferhat ;
Stephan, François ;
Nseir, Saad ;
Gibot, Sebastien ;
Schwebel, Carole ;
Plantefeve, Gaetan ;
Diehl, Jean-Luc ;
Richard, Christian ;
Lamer, Christian ;
Klouche, Kada ;
Jaber, Samir ;
Zakynthinos, Epaminondas ;
Filntisis, Georgios ;
Zakynthinos, Spyros ;
Koutsoukou, Antonia ;
Saroglou, Georgios ;
Nikolaou, Charikleia ;
Vlachogianni, Glykeria ;
Pnevmatikos, Ioannis ;
Mandragos, Konstantinos ;
Kremer, Ildiko ;
Rozgonyi, Zsolt Dezso ;
Marjanek, Zsuzsa ;
Martin-Loeches, Ignacio ;
Singer, Pierre ;
Van Heerden, Vernon ;
Carmeli, Yehuda ;
Povoa, Pedro ;
AlvarezSeoane, Antonio ;
Moura, Pedro ;
Gonzalez, Filipe ;
Ramirez, Paula ;
Torres Marti, Antonio ;
Ferrer Roca, Ricard ;
Oteiza, Lorena ;
Escudero, Dolores ;
Piacentini, Enrique ;
Vera-Artazcoz, Paula (Institut d'Investigació Biomèdica Sant Pau) ;
Tamayo, Luis ;
Gonzalez Gallego, Miguel Angel ;
Suberviola Canas, Borja ;
Figueira, Iglesias ;
Leon, Rafael ;
Korten, Volkan ;
Akova, Murat ;
Wyncoll, Duncan ;
Whitehouse, Tony ;
Hopkins, Phil ;
Sim, Malcolm ;
Golan, Yoav ;
Zervos, Marcus ;
Vazquez, Jose ;
Cherabuddi, Kartikeya ;
Smulian, George ;
Rouphael, Nadine ;
Welker, James ;
Sims, Mathew ;
Van Duin, David ;
McCarthy, Todd ;
Polk, Christopher
Background: Ventilator-associated pneumonia caused by Pseudomonas aeruginosa (PA) in hospitalised patients is associated with high mortality. The effectiveness of the bivalent, bispecific mAb MEDI3902 (gremubamab) in preventing PA nosocomial pneumonia was assessed in PA-colonised mechanically ventilated subjects. [...]
2022 - 10.1186/s13054-022-04204-9
Critical Care, Vol. 26 Núm. 1 (december 2022) , p. 355
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4.
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11 p, 1.3 MB |
Relationship between ventilator-associated pneumonia and mortality in COVID-19 patients : a planned ancillary analysis of the coVAPid cohort
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Nseir, Saad (Universitè de Lille) ;
Martin-Loeches, Ignacio (Hospital Clínic i Provincial de Barcelona) ;
Povoa, Pedro (Odense University Hospital (Dinamarca)) ;
Metzelard, Matthieu (Amiens University Hospital) ;
Du Cheyron, Damien (Caen University Hospital (França)) ;
Lambiotte, Fabien (Centre Hospitalier de Valenciennes) ;
Tamion, Fabienne (Rouen University Hospital (França)) ;
Labruyere, Marie (François Mitterrand University Hospital) ;
Makris, Demosthenes (General University Hospital of Larissa (Grècia)) ;
Boulle Geronimi, Claire (Centre Hospitalier de Douai) ;
Pinetonde Chambrun, Marc (Hôpital Pitié-Salpêtrière) ;
Nyunga, Martine (Roubaix Hospital (França)) ;
Pouly, Olivier (Université Catholique (França)) ;
Mégarbane, Bruno (Université de Paris) ;
Saade, Anastasia (Hôpital Saint-Louis (França)) ;
Gomà, Gemma (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Magira, Eleni (National and Kapodistrian University of Athens Medical School) ;
Llitjos, Jean-François (Université de Paris) ;
Torres, Antoni (Hospital Clínic i Provincial de Barcelona) ;
Ioannidou, Iliana (National and Kapodistrian University of Athens) ;
Pierre, Alexandre (Réanimation Polyvalente (França)) ;
Coelho, Luis (São Francisco Xavier Hospital) ;
Reignier, Jean (CHU de Nantes) ;
Garot, Denis (CHU de Tours) ;
Kreitmann, Louis (Hôpital Edouard Herriot) ;
Baudel, Jean-Luc (Assistance Publique-Hôpitaux de Paris) ;
Voiriot, Guillaume (Sorbonne Université) ;
Contou, Damien (CH Victor Dupouy) ;
Beurton, Alexandra (Sorbonne Université) ;
Asfar, Pierre (Université D'Angers) ;
Boyer, Alexandre (Bordeaux University Hospital (França)) ;
Thille, Arnaud W. (Université de Poitiers) ;
Mekontso-Dessap, Armand (Université Paris Est-Créteil) ;
Tsolaki, Vassiliki (General University Hospital of Larissa (Grècia)) ;
Vinsonneau, Christophe (Centre Hospitalier de Béthune, Réseau de Recherche Boréal. Service de Médecine Intensive Réanimation) ;
Floch, Pierre-Edouard (Service de Réanimation, Hôpital Duchenne, Rue Monod, 62200 Boulogne-sur-Mer, France) ;
Le Guennec, Loïc (Unité de Médecine Intensive Réanimation Neurologique. Sorbonne Université, AP-HP, Hôpital de La Pitié-Salpêtrière, Département de Neurologie) ;
Ceccato, Adrian (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Bouchereau, Mathilde (CHU de Lille) ;
Labreuche, Julien (Université Lille) ;
Duhamel, Alain (Université Lille) ;
Rouzé, Anahita (Université Lille) ;
Universitat Autònoma de Barcelona
Patients with SARS-CoV-2 infection are at higher risk for ventilator-associated pneumonia (VAP). No study has evaluated the relationship between VAP and mortality in this population, or compared this relationship between SARS-CoV-2 patients and other populations. [...]
2021 - 10.1186/s13054-021-03588-4
Critical Care, Vol. 25 (may 2021)
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13 p, 695.7 KB |
The value of polyurethane-cuffed endotracheal tubes to reduce microaspiration and intubation-related pneumonia : a systematic review of laboratory and clinical studies
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Blot, Stijn (Ghent University, Belgium) ;
Rello, Jordi (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Koulenti, Despoina (University General Hospital Attikon (Haidari, Grècia))
When conventional high-volume, low-pressure cuffs of endotracheal tubes (ETTs) are inflated, channel formation due to folds in the cuff wall can occur. These channels facilitate microaspiration of subglottic secretions, which is the main pathogenic mechanism leading to intubation-related pneumonia. [...]
2016 - 10.1186/s13054-016-1380-8
Critical Care, Vol. 20 (june 2016)
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8 p, 896.3 KB |
Incidence of airway complications in patients using endotracheal tubes with continuous aspiration of subglottic secretions
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Vallés, Jordi (Universitat Autònoma de Barcelona) ;
Millán, Susana (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Díaz-Aparicio, Efren (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Castanyer, Eva (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Gallardo, Xavier (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Martín-Loeches, Ignacio (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Andreu, Marta (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Prenafeta, Mario (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Saludes, Paula (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Lema, Jorge (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Batlle, Montse (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Bacelar, Néstor (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Continuous aspiration of subglottic secretions is effective in preventing ventilator-associated pneumonia, but it involves a risk of mucosal damage. The main objective of our study was to determine the incidence of airway complications related to continuous aspiration of subglottic secretions. [...]
2017 - 10.1186/s13613-017-0331-0
Annals of Intensive Care, Vol. 7 (november 2017)
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11 p, 634.7 KB |
Characteristics and Outcomes in Patients with Ventilator-Associated Pneumonia Who Do or Do Not Develop Acute Respiratory Distress Syndrome. An Observational Study
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Barbeta, Enric (Hospital del Sagrat Cor (Catalunya)) ;
Ceccato, Adrian (Hospital del Sagrat Cor (Catalunya)) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Ferrer, Miquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Fernández-Barat, Laia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
López, Rubén (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Bueno, Leticia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Motos, Anna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Li Bassi, Gianluigi (The Prince Charles Hospital) ;
Mellado, Ricard (Hospital Clínic i Provincial de Barcelona) ;
Ferrando, Carlos (Hospital Clínic i Provincial de Barcelona) ;
Palomeque, Andrea Catalina (Hospital Clínic i Provincial de Barcelona) ;
Panigada, Mauro (Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
Gabarrús, Albert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
de Mendoza, Diego (Hospital del Sagrat Cor (Catalunya)) ;
Torres, Antoni (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Universitat Autònoma de Barcelona
Ventilator-associated pneumonia (VAP) is a well-known complication of patients on invasive mechanical ventilation. The main cause of acute respiratory distress syndrome (ARDS) is pneumonia. ARDS can occur in patients with community-acquired or nosocomial pneumonia. [...]
2020 - 10.3390/jcm9113508
Journal of clinical medicine, Vol. 9 (october 2020)
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15 p, 964.8 KB |
Appraisal of systemic inflammation and diagnostic markers in a porcine model of VAP : secondary analysis from a study on novel preventive strategies
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Li Bassi, Gianluigi (Universitat de Barcelona) ;
Prats, Raquel Guillamat (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Xiol, Eli Aguilera (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Marti, Joan-Daniel (Hospital Clínic i Provincial de Barcelona) ;
Ranzani, Otavio T. (Hospital Clínic i Provincial de Barcelona) ;
Rigol, Montserrat (Hospital Clínic i Provincial de Barcelona) ;
Fernandez, Laia (Universitat de Barcelona) ;
Meli, Andrea (Universita degli Studi di Milano. Dipartimento di Anestesia e Rianimazione, ASST Santi Paolo e Carlo, Dipartimento di Scienza e Salute) ;
Battaglini, Denise (Università degli Studi di Genova. Dipartimento Scienze Chirurgiche e Diagnostiche Integrate (DISC)) ;
Luque, Nestor (Hospital Clínic i Provincial de Barcelona) ;
Ferrer, Miguel (Universitat de Barcelona) ;
Martin-Loeches, Ignacio (Multidisciplinary Intensive Care Research Organization (MICRO), Department of Clinical Medicine, Trinity Centre for Health Sciences, St James's University Hospital, Dublin, Ireland) ;
Póvoa, Pedro (New University of Lisbon. NOVA Medical School, CEDOC) ;
Chiumello, Davide (Universita degli Studi di Milano. Dipartimento di Anestesia e Rianimazione, ASST Santi Paolo e Carlo, Dipartimento di Scienza e Salute) ;
Pelosi, Paolo (Università degli Studi di Genova. Dipartimento Scienze Chirurgiche e Diagnostiche Integrate (DISC)) ;
Torres, Antoni (Universitat de Barcelona) ;
Universitat Autònoma de Barcelona
We previously evaluated the efficacy of a ventilatory strategy to achieve expiratory flow bias and positive end-expiratory pressure (EFB + PEEP) or the Trendelenburg position (TP) for the prevention of ventilator-associated pneumonia (VAP). [...]
2018 Support was provided by the Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Ministerio de Ciencia e Innovación; European Society of Intensive Care Medicine-ESICM (2009 Alain Harf Award on Applied Respiratory Physiology); Fundació Catalana de Pneumologıa (FUCAP); Sociedad Española de Neumología y Cirugía Torácica (SEPAR); Centro de Investigación Biomedica En Red-Enfermedades Respiratorias, (CIBERES) - 10.1186/s40635-018-0206-1
Intensive Care Medicine Experimental, Vol. 6 (october 2018)
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9.
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7 p, 497.0 KB |
Lower Respiratory Tract Infection and Short-Term Outcome in Patients With Acute Respiratory Distress Syndrome
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Zampieri, Fernando G. (Hospital do Coração, São Paulo, Brazil) ;
Póvoa, Pedro (Nova Medical School, CEDOC, New University of Lisbon, Lisbon, Portugal) ;
Salluh, Jorge I. (Programa de Pós-graduação em Clínica Médica, Universidade Federal do Rio de Janeiro, Rio Janeiro, Brazil) ;
Rodríguez, Alejandro (Hospital Universitari Joan XXIII de Tarragona) ;
Valade, Sandrine (Intensive Care Unit, Saint-Louis University Hospital, AP-HP and Paris-Diderot University, Sorbonne Paris Cité, Paris, France) ;
Andrade Gomes, José (Hospital da Luz (Lisboa, Portugal)) ;
Reignier, Jean (Medical ICU, CHU de Nantes, Nantes, France) ;
Molinos, Elena (Serviço de Medicina Intensiva, Hospital Pedro Hispano, ULS de Matosinhos, Matosinhos, Portugal) ;
Almirall i Pujol, Jordi (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Boussekey, Nicolas (Service de Réanimation Médicale et Maladies Infectieuses, Hôpital Chatiliez, Tourcoing, France) ;
Socias, Lorenzo (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
Ramirez, Paula (Hospital Universitari i Politècnic La Fe (València)) ;
Viana, William N. (Hospital Copa D'Or, Copacabana, Rio de Janeiro, Brazil) ;
Rouzé, Anahita (University Hospital of Lille (França)) ;
Nseir, Saad (University Hospital of Lille (França)) ;
Martin-Loeches, Ignacio (Welcome Trust-HRB Clinical Research Facility, St James Hospital, Dublin, Ireland)
To assess whether ventilator-associated lower respiratory tract infections (VA-LRTIs) are associated with mortality in critically ill patients with acute respiratory distress syndrome (ARDS). Post hoc analysis of prospective cohort study including mechanically ventilated patients from a multicenter prospective observational study (TAVeM study); VA-LRTI was defined as either ventilator-associated tracheobronchitis (VAT) or ventilator-associated pneumonia (VAP) based on clinical criteria and microbiological confirmation. [...]
2018 - 10.1177/0885066618772498
Journal of Intensive Care Medicine, Vol. 35 (april 2018) , p. 588-594
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13 p, 818.7 KB |
Ventilator-Associated Pneumonia due to Drug-Resistant Acinetobacter baumannii : Risk Factors and Mortality Relation with Resistance Profiles, and Independent Predictors of In-Hospital Mortality
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Čiginskienė, Aušra (Department of Intensive Care, Medical Academy, Lithuanian University of Health Sciences Lithuania) ;
Dambrauskienė, Asta (Infection Control Service, Medical Academy, Lithuanian University of Health Science) ;
Rello, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Adukauskienė, Dalia (Department of Intensive Care, Medical Academy, Lithuanian University of Health Sciences) ;
Universitat Autònoma de Barcelona
Background and objectives: High mortality and healthcare costs area associated with ventilator-associated pneumonia (VAP) due to Acinetobacter baumannii (A. baumannii). The data concerning the link between multidrug-resistance of A. [...]
2019 - 10.3390/medicina55020049
Medicina, Vol. 55 (february 2019)
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