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1.
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16 p, 1.9 MB |
Cross-sectional evaluation of circulating hepatitis B virus RNA and DNA : Different quasispecies?
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García-García, Selene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Cortese, Maria Francesca (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Tabernero, David (Instituto de Salud Carlos II) ;
Gregori i Font, Josep (Instituto de Salud Carlos II) ;
Vila, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pacín Ruiz, Beatriz (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Quer, Josep 1963- (Instituto de Salud Carlos II) ;
Casillas, Rosario (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Castillo-Ribelles, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ferrer-Costa, Roser (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rando-Segura, Ariadna (Hospital Universitari Vall d'Hebron) ;
Trejo-Zahínos, Jesús (Hospital Universitari Vall d'Hebron) ;
Pumarola Suñé, Tomàs (Hospital Universitari Vall d'Hebron) ;
Casis-Saez, Ernesto (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Esteban, Rafael (Instituto de Salud Carlos II) ;
Riveiro Barciela, Mar (Instituto de Salud Carlos II) ;
Buti, Maria (Instituto de Salud Carlos II) ;
Rodríguez Frías, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Different forms of pregenomic and other hepatitis B virus (HBV) RNA have been detected in patients' sera. These circulating HBV-RNAs may be useful for monitoring covalently closed circular DNA activity, and predicting hepatitis B e-antigen seroconversion or viral rebound after nucleos(t)ide analog cessation. [...]
2021 -  10.3748/wjg.v27.i41.7144
World Journal of Gastroenterology, Vol. 27 (november 2021) , p. 7144-7158
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2.
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9 p, 2.1 MB |
Effect of Hepatitis E Virus RNA Universal Blood Donor Screening, Catalonia, Spain, 2017-2020
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Bes, Marta (Banc de Sang i Teixits (Barcelona, Catalunya)) ;
Costafreda Salvany, Maria Isabel (Banc de Sang i Teixits) ;
Riveiro-Barciela, M. (Hospital Universitari Vall d'Hebron) ;
Piron, M. (Banc de Sang i Teixits) ;
Rico, A. (Banc de Sang i Teixits) ;
Quer, J. (Hospital Universitari Vall d'Hebron) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Sauleda, S. (Banc de Sang i Teixits)
Hepatitis E virus (HEV) is the major cause of acute viral hepatitis in several countries in Europe. HEV is acquired mainly by consumption of contaminated pork but can also be transmitted through blood transfusion. [...]
2022 - 10.3201/eid2801.211466
Emerging Infectious Diseases, Vol. 28 Núm. 1 (january 2022) , p. 157-165
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3.
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10 p, 13.8 MB |
Argonaute 2 Controls Antiviral Activity against Sweet Potato Mild Mottle Virus in Nicotiana benthamiana
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Kenesi, Erzsébet (Institute of Plant Biology) ;
Lopez-Moya, Juan Jose (Centre de Recerca en Agrigenòmica) ;
Orosz, László (University of Szeged. Department of Medical Microbiology and Immunobiology) ;
Burgyán, József (Agricultural Biotechnology Institute) ;
Lakatos, Lóránt (Institute of Plant Biology)
RNA silencing is a sequence specific post-transcriptional mechanism regulating important biological processes including antiviral defense in plants. Argonaute (AGO) proteins, the catalytic subunits of the silencing complexes, are loaded with small RNAs to execute the sequence specific RNA cleavage or translational inhibition. [...]
2021 - 10.3390/plants10050867
Plants, Vol. 10, Issue 5 (April 2021) , art. 867
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4.
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13 p, 2.4 MB |
The P1 Protein of Watermelon mosaic virus Compromises the Activity as RNA Silencing Suppressor of the P25 Protein of Cucurbit yellow stunting disorder virus
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Domingo Calap, María Luisa (Centre de Recerca en Agrigenòmica) ;
Chase, Ornela (Centre de Recerca en Agrigenòmica) ;
Estapé, Mariona (Centre de Recerca en Agrigenòmica) ;
Moreno, Ana Beatriz (Centre de Recerca en Agrigenòmica) ;
Lopez-Moya, Juan Jose (Centre de Recerca en Agrigenòmica)
Mixed viral infections in plants involving a potyvirus and other unrelated virus often result in synergistic effects, with significant increases in accumulation of the non-potyvirus partner, as in the case of melon plants infected by the potyvirus Watermelon mosaic virus (WMV) and the crinivirus Cucurbit yellow stunting disorder virus (CYSDV). [...]
2021 - 10.3389/fmicb.2021.645530
Frontiers in microbiology, Vol. 12 (March 2021) , art. 645530
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5.
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6.
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7.
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11 p, 1.2 MB |
Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients
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García-López, Mireia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Lens, Sabela (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Pallett, Laura J. (University College London) ;
Testoni, Barbara (University of Lyon) ;
Rodríguez-Tajes, Sergio (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Mariño, Zoe (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Bartres, Concepció (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
García-Pras, Ester (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Leonel, Thais (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Perpiñán, Elena (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Lozano, Juan José (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Rodríguez Frías, Francisco (Hospital Universitari Vall d'Hebron) ;
Koutsoudakis, George (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Zoulim, Fabien (University of Lyon) ;
Maini, Mala K. (University College London) ;
Forns, Xavier (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Pérez-Del-Pulgar, Sofía (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Universitat Autònoma de Barcelona
Factors associated with a successful outcome upon nucleos(t)ide analogue (NA) treatment withdrawal in HBeAg-negative chronic hepatitis B (CHB) patients have yet to be clarified. The objective of this study was to analyse the HBV-specific T cell response, in parallel with peripheral and intrahepatic viral parameters, in patients undergoing NA discontinuation. [...]
2021 - 10.1016/j.jhep.2020.11.043
Journal of Hepatology, Vol. 74 (may 2021) , p. 1064-1074
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8.
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16 p, 3.5 MB |
Conservation and variability of hepatitis B core at different chronic hepatitis stages
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Yll, Marçal (Hospital Universitari Vall d'Hebron) ;
Cortese, Maria Francesca (Hospital Universitari Vall d'Hebron) ;
Guerrero Murillo, Mercedes (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Orriols, Gerard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gregori i Font, Josep (Hospital Universitari Vall d'Hebron) ;
Casillas, Rosario (Hospital Universitari Vall d'Hebron) ;
González, Carolina (Hospital Universitari Vall d'Hebron) ;
Sopena, Sara (Hospital Universitari Vall d'Hebron) ;
Godoy, Cristina (Hospital Universitari Vall d'Hebron) ;
Vila, Marta (Hospital Universitari Vall d'Hebron) ;
Tabernero, David (Hospital Universitari Vall d'Hebron) ;
Quer, Josep 1963- (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rando-Segura, Ariadna (Hospital Universitari Vall d'Hebron) ;
Lopez Martinez, Rosa (Hospital Universitari Vall d'Hebron) ;
Esteban, Rafael (Esteban Mur) (Hospital Universitari Vall d'Hebron) ;
Riveiro Barciela, Mar (Hospital Universitari Vall d'Hebron) ;
Buti, Maria (Hospital Universitari Vall d'Hebron) ;
Rodríguez Frías, Francisco (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Since it is currently not possible to eradicate hepatitis B virus (HBV) infection with existing treatments, research continues to uncover new therapeutic strategies. HBV core protein, encoded by the HBV core gene (HBC), intervenes in both structural and functional processes, and is a key protein in the HBV life cycle. [...]
2020 - 10.3748/wjg.v26.i20.2584
World Journal of Gastroenterology, Vol. 26 (may 2020) , p. 2584-2598
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9.
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13 p, 2.8 MB |
High levels of unreported intraspecific diversity among RNA viruses in faeces of neonatal piglets with diarrhoea
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Cortey, Martí (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Díaz, Ivan. (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Vidal, Anna (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Martín-Valls, Gerard (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Franzo, Giovanni (University of Padova. Department of Animal Medicine Production and Health (MAPS)) ;
Gómez De Nova, P. J. (Universidad de León. Departamento de Sanidad Animal) ;
Darwich Soliva, Laila (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Puente, H. (Universidad de León. Departamento de Sanidad Animal) ;
Carvajal, A. (Universidad de León. Departamento de Sanidad Animal) ;
Martín Castillo, Margarita (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Mateu de Antonio, Enrique María (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Background: Diarrhoea is a major cause of death in neonate pigs and most of the viruses that cause it are RNA viruses. Next Generation Sequencing (NGS) deeply characterize the genetic diversity among rapidly mutating virus populations at the interspecific as well as the intraspecific level. [...]
2019 - 10.1186/s12917-019-2204-2
BMC veterinary research, Vol. 15 Núm. 1 (may 2019) , p. 441
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10.
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15 p, 4.6 MB |
Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab
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Serra-Peinado, Carla (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Grau Expósito, Judith (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Luque-Ballesteros, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Astorga-Gamaza, Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Navarro, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gallego-Rodriguez, Jenny (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martín Castillo, Mario (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Curran, Adrian (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Burgos, Joaquín (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribera, Esteban (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Raventós, Berta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Willekens, Rein (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Torrella Domingo, Adriana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Planas, Bibiana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Badía, Rosa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
García, Felipe (Hospital Clínic i Provincial de Barcelona) ;
Castellvi, Josep (Hospital Universitari Vall d'Hebron) ;
Genescà Ferrer, Meritxell (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Falcó, Vicenç (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Buzón, Maria José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
The identification of exclusive markers to target HIV-reservoir cells will represent a significant advance in the search for therapies to cure HIV. Here, we identify the B lymphocyte antigen CD20 as a marker for HIV-infected cells in vitro and in vivo. [...]
2019 - 10.1038/s41467-019-11556-4
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 3705
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