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6 p, 2.2 MB Low-cost diagnostic test for susceptible and drug-resistant tuberculosis in rural Malawi / Zhang, Annie (Department of Microbiology, College of Arts and Sciences, The Ohio State University, Columbus, Ohio, United States) ; Jumbe, Enoch (Child Legacy International, Msundwe, Lilongwe, Malawi) ; Krysiak, Robert (Department of Infectious Diseases, School of Medicine, University of North Carolina Project, Tidziwe Centre, Lilongwe, Malawi) ; Sidiki, Sabeen (Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, Ohio, United States) ; Kelley, Holden V. (Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, Ohio, United States) ; Chemey, Elly K. (Child Legacy International, Msundwe, Lilongwe, Malawi) ; Kamba, Chancy (District Tuberculosis Control Office, Ministry of Health, Lilongwe, Malawi) ; Mwapasa, Victor (Department of Community Health, College of Medicine, Blantyre, Malawi) ; García, Juan I. (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Norris, Alison (College of Public Health, The Ohio State University, Columbus, Ohio, United States) ; Pan, Xueliang J. (Center for Biostatistics, College of Medicine, The Ohio State University, Columbus, Ohio, United States) ; Evans, Carlton (Department of Microbiology, Cayetano Heredia University, Lima, Peru) ; Wang, Shu-Hua (Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States) ; Kwiek, Jesse J. (Department of Microbiology, College of Arts and Sciences, The Ohio State University, Columbus, Ohio, United States) ; Torrelles, Jordi B. (Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, Ohio, United States)
Rural settings where molecular tuberculosis diagnostics are not currently available need easy-to-use tests that do not require additional processing or equipment. While acid-fast bacilli (AFB) smear is the most common and often only tuberculosis diagnosis test performed in rural settings, it is labour intensive, has less-than-ideal sensitivity, and cannot assess tuberculosis drug susceptibility patterns. [...]
2018 - 10.4102/ajlm.v7i1.690
African Journal of Laboratory Medicine, Vol. 7 (june 2018)  

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