Depósito Digital de Documentos de la UAB Encontrados 21 registros  1 - 10siguientefinal  ir al registro: La búsqueda tardó 0.00 segundos. 
1.
11 p, 3.1 MB GPCRtm : An amino acid substitution matrix for the transmembrane region of class A G Protein-Coupled Receptors / Rios Azuara, Santiago (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Fernandez, Marta F. (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Caltabiano, Gianluigi 1978- (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Campillo Grau, María Mercedes (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Pardo Carrasco, Leonardo (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; González Wong, Angel (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional)
Protein sequence alignments and database search methods use standard scoring matrices calculated from amino acid substitution frequencies in general sets of proteins. These general-purpose matrices are not optimal to align accurately sequences with marked compositional biases, such as hydrophobic transmembrane regions found in membrane proteins. [...]
2015 - 10.1186/s12859-015-0639-4
BMC Bioinformatics, Vol. 16 (July 2015) , art. 2016  
2.
13 p, 2.1 MB Population genetic analysis of bi-allelic structural variants from low-coverage sequence data with an expectation-maximization algorithm / Lucas-Lledó, José Ignacio (Leibniz-Institute of Freshwater Ecology and Inland Fisheries (IGB)) ; Vicente Salvador, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Aguado, Cristina (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cáceres Aguilar, Mario (Institució Catalana de Recerca i Estudis Avançats)
Population genetics and association studies usually rely on a set of known variable sites that are then genotyped in subsequent samples, because it is easier to genotype than to discover the variation. [...]
2014 - 10.1186/1471-2105-15-163
BMC Bioinformatics, Vol. 15 (May 2014) , art. 163  
3.
7 p, 968.3 KB Qxpak.5 : old mixed model solutions for new genomics problems / Pérez-Enciso, Miguel (Centre de Recerca en Agrigenòmica) ; Misztal, Ignacy (University of Georgia. Department of Animal and Dairy Science)
Mixed models have a long and fruitful history in statistics. They are pertinent to genomics problems because they are highly versatile, accommodating a wide variety of situations within the same theoretical and algorithmic framework. [...]
2011 - 10.1186/1471-2105-12-202
BMC Bioinformatics, Vol. 12 (May 2011) , art. 202  
4.
8 p, 741.7 KB PCOPGene-Net : holistic characterisation of cellular states from microarray data based on continuous and non-continuous analysis of gene-expression relationships / Huerta Casado, Mario (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cedano Rodríguez, Juan Antonio (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Peña, Dario (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Rodriguez, Antonio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Querol Murillo, Enrique (Instituto de Biotecnología y Biomedicina "Vicent Villar Palasi")
Microarray technology is so expensive and powerful that it is essential to extract maximum value from microarray data, specially from large-sample-series microarrays. Our web tools attempt to respond to these researchers' needs by facilitating the possibility to test and formulate from a hypothesis to entire models under a holistic point of view. [...]
2009 - 10.1186/1471-2105-10-138
BMC Bioinformatics, Vol. 10 (2009) , art. 138  
5.
14 p, 1.9 MB Label noise in subtype discrimination of class C G protein-coupled receptors : a systematic approach to the analysis of classification errors / König, Caroline (Universitat Politècnica de Catalunya. Departament de Ciencies de la Computació) ; Cárdenas, Martha I. (Universitat Politècnica de Catalunya. Departament de Ciencies de la Computació) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Alquézar, René (Universitat Politècnica de Catalunya. Departament de Ciencies de la Computació) ; Vellido, Alfredo (Universitat Politècnica de Catalunya. Departament de Llenguatges i Sistemes Informàtics)
Background: The characterization of proteins in families and subfamilies, at different levels, entails the definition and use of class labels. When the adscription of a protein to a family is uncertain, or even wrong, this becomes an instance of what has come to be known as a label noise problem. [...]
2015 - 10.1186/s12859-015-0731-9
BMC Bioinformatics, Vol. 16, N. 314 (September 2015) , p. 1-14  
6.
15 p, 1.6 MB Quantifying conformational changes in GPCRs : glimpse of a common functional mechanism / Dalton, James A.R. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Lans, Isaias (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències)
Background: G-protein-coupled receptors (GPCRs) are important drug targets and a better understanding of their molecular mechanisms would be desirable. The crystallization rate of GPCRs has accelerated in recent years as techniques have become more sophisticated, particularly with respect to Class A GPCRs interacting with G-proteins. [...]
2015 - 10.1186/s12859-015-0567-3
BMC Bioinformatics, Vol. 16 N. 124 (April 2015) , p. 1-15  
7.
11 p, 2.4 MB From raw data to data-analysis for magnetic resonance spectroscopy – the missing link : jMRUI2XML / Mocioiu, Victor (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Ortega-Martorell, Sandra (Liverpool John Moores University. Department of Mathematics and Statistics) ; Olier, Iván (University of Manchester. Institute of Population Health) ; Jablonski, Michal (Institute of Scientific Instruments of the CAS (Brno, República Txeca)) ; Starcukova, Jana (Institute of Scientific Instruments of the CAS (Brno, República Txeca)) ; Lisboa, Paulo J. G. (Liverpool John Moores University. Department of Mathematics and Statistics) ; Arús i Caraltó, Carles (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Julià Sapé, Ma. Margarita (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Background: Magnetic resonance spectroscopy provides metabolic information about living tissues in a non-invasive way. However, there are only few multi-centre clinical studies, mostly performed on a single scanner model or data format, as there is no flexible way of documenting and exchanging processed magnetic resonance spectroscopy data in digital format. [...]
2015 - 10.1186/s12859-015-0796-5
BMC Bioinformatics, Vol. 16, N. 378 (November 2015) , p. 1-11  
8.
20 p, 570.3 KB Non-negative matrix factorisation methods for the spectral decomposition of MRS data from human brain tumours / Ortega-Martorell, Sandra (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Lisboa, Paulo J. G. (Liverpool John Moores University. Department of Mathematics and Statistics) ; Vellido, Alfredo (Universitat Politècnica de Catalunya. Departament de Llenguatges i Sistemes Informàtics) ; Julià Sapé, Ma. Margarita (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Arús i Caraltó, Carles (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Background: In-vivo single voxel proton magnetic resonance spectroscopy (SV 1H-MRS), coupled with supervised pattern recognition (PR) methods, has been widely used in clinical studies of discrimination of brain tumour types and follow-up of patients bearing abnormal brain masses. [...]
2012 - 10.1186/1471-2105-13-38
BMC Bioinformatics, Vol. 13, N. 38 (March 2012) , p. 1-20  
9.
17 p, 2.5 MB DCE@urLAB : a dynamic contrast-enhanced MRI pharmacokinetic analysis tool for preclinical data / Ortuño, Juan E. (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Saragosssa, Aragó)) ; Ledesma Carbayo, María J. (Universidad Politécnica de Madrid. Departamento de Ingeniería Electrónica) ; Simões, Rui V. (Universitat de Barcelona) ; Candiota Silveira, Ana Paula (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Arús i Caraltó, Carles (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Santos, Andrés (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Saragosssa, Aragó))
Background: DCE@urLAB is a software application for analysis of dynamic contrast-enhanced magnetic resonance imaging data (DCE-MRI). The tool incorporates a friendly graphical user interface (GUI) to interactively select and analyze a region of interest (ROI) within the image set, taking into account the tissue concentration of the contrast agent (CA) and its effect on pixel intensity. [...]
2013 - 10.1186/1471-2105-14-316
BMC Bioinformatics, Vol. 14, N. 316 (November 2013) , p. 1-17  
10.
7 p, 1.2 MB designGG : an R-package and web tool for the optimal design of genetical genomics experiments / Li, Yang (University of Groningen. Groningen Biomolecular Sciences and Biotechnology Institute (Haren, Països Baixos)) ; Swertz, Morris A. (University of Groningen. Groningen Biomolecular Sciences and Biotechnology Institute (Haren, Països Baixos)) ; Vera Rodríguez, Gonzalo (University of Groningen. Groningen Biomolecular Sciences and Biotechnology Institute (Haren, Països Baixos)) ; Fu, Jingyuan (University of Groningen. Department of Genetics (Groningen, Països Baixos)) ; Breitling, Rainer (University of Groningen. Groningen Biomolecular Sciences and Biotechnology Institute (Haren, Països Baixos)) ; Jansen, Ritsert C. (University of Groningen. Groningen Biomolecular Sciences and Biotechnology Institute (Haren, Països Baixos))
Background: High-dimensional biomolecular profiling of genetically different individuals in one or more environmental conditions is an increasingly popular strategy for exploring the functioning of complex biological systems. [...]
2009 - 10.1186/1471-2105-10-188
BMC Bioinformatics, Vol. 10, N. 188 (June 2009) , p. 1-7  

Depósito Digital de Documentos de la UAB : Encontrados 21 registros   1 - 10siguientefinal  ir al registro:
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