UAB Digital Repository of Documents 4 records found  Search took 0.01 seconds. 
1.
7 p, 409.8 KB An evolutionary conserved region (ECR) in the human dopamine receptor D4 gene supports reporter gene expression in primary cultures derived from the rat cortex / Paredes, Ursula M. (University of Liverpool. Institute of Translational Medicine) ; Bubb, Vivien J. (University of Liverpool. Institute of Translational Medicine) ; Haddley, Katte (University of Liverpool. Institute of Translational Medicine) ; Macho, Gabriele A. (Institut Català de Paleontologia Miquel Crusafont) ; Quinn, John P. (University of Liverpool. Institute of Translational Medicine)
Background: detecting functional variants contributing to diversity of behaviour is crucial for dissecting genetics of complex behaviours. At a molecular level, characterisation of variation in exons has been studied as they are easily identified in the current genome annotation although the functional consequences are less well understood; however, it has been difficult to prioritise regions of non-coding DNA in which genetic variation could also have significant functional consequences. [...]
2011 - 10.1186/1471-2202-12-46
BMC neuroscience, Vol. 12 (2011) , art. 46  
2.
10 p, 1.4 MB Brain metabolic pattern analysis using a magnetic resonance spectra classification software in experimental stroke / Jiménez Xarrié, Elena (Institut d'Investigació Biomèdica de Sant Pau. Unitat de Malalties Vasculars Cerebrals) ; Dávila Huerta, Myriam (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Candiota Silveira, Ana Paula (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Delgado-Mederos, Raquel (Institut d'Investigació Biomèdica de Sant Pau. Unitat de Malalties Vasculars Cerebrals) ; Ortega-Martorell, Sandra (Liverpool John Moores University. Department of Applied Mathematics) ; Julià Sapé, Ma. Margarita (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Arús i Caraltó, Carles (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica de Sant Pau. Unitat de Malalties Vasculars Cerebrals)
Magnetic resonance spectroscopy (MRS) provides non-invasive information about the metabolic pattern of the brain parenchyma in vivo. The SpectraClassifier software performs MRS pattern-recognition by determining the spectral features (metabolites) which can be used objectively to classify spectra. [...]
2017 - 10.1186/s12868-016-0328-x
BMC Neuroscience, Vol. 18, issue 1 (Jan. 2017) , art. 13  
3.
11 p, 970.6 KB Neuroprotection from NMDA excitotoxic lesion by Cu/Zn superoxide dismutase gene delivery to the postnatal rat brain by a modular protein vector / Peluffo, Hugo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Acarín Pérez, Laia (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Arís i Giralt, Anna (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; González, Pau (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Castellano López, Bernardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; González, Berta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Background: Superoxide mediated oxidative stress is a key neuropathologic mechanism in acute central nervous system injuries. We have analyzed the neuroprotective efficacy of the transient overexpression of antioxidant enzyme Cu/Zn Superoxide dismutase (SOD) after excitotoxic injury to the immature rat brain by using a recently constructed modular protein vector for non-viral gene delivery termed NLSCt. [...]
2006 - 10.1186/1471-2202-7-35
BMC Neuroscience, Vol. 7, Núm. 35 (April 2006) , p. 1-11  
4.
16 p, 4.4 MB Proliferation dynamics of germinative zone cells in the intact and excitotoxically lesioned postnatal rat brain / Faiz, Maryam (Universitat Autònoma de Barcelona. Unitat d'Histologia) ; Acarín Pérez, Laia (Universitat Autònoma de Barcelona. Unitat d'Histologia) ; González, Berta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Castellano López, Bernardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Background: The forebrain subventricular zone (SVZ)-olfactory bulb pathway and hippocampal subgranular zone (SGZ) generate neurons into adulthood in the mammalian brain. Neurogenesis increases after injury to the adult brain, but few studies examine the effect of injury on neural and glial precursors in the postnatal brain. [...]
2005 - 10.1186/1471-2202-6-26
BMC Neuroscience, Vol. 6, N. 26 (April 2005) , p. 1-16  

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