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8 p, 1.5 MB Non-pharmacological Effects in Switching Medication : The Nocebo Effect in Switching from Originator to Biosimilar Agent / Kristensen, Lars Erik (Lund University. Department of Internal Medicine, Rheumatology) ; Alten, Rieke (Schlosspark Klinik, University Medicine Berlin. Department of Internal Medicine, Rheumatology) ; Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ; Philipp, Sandra (Charité - Universitätsmedizin Berlin) ; Kvien, Tore K. (Diakonhjemmet Hospital. Department of Rheumatology) ; Mangues, Ma Antonia (Institut d'Investigació Biomèdica Sant Pau) ; van den Hoogen, Frank (Radboud University Medical Centre. Department of Rheumatology) ; Pavelka, Karel (Institute of Rheumatology) ; Vulto, Arnold G. (KU Leuven. Department of Pharmaceutical and Pharmacological Sciences) ; Universitat Autònoma de Barcelona
The nocebo effect is defined as the incitement or the worsening of symptoms induced by any negative attitude from non-pharmacological therapeutic intervention, sham, or active therapies. When a patient anticipates a negative effect associated with an intervention, medication or change in medication, they may then experience either an increase in this effect or experience it de novo. [...]
2018 - 10.1007/s40259-018-0306-1
Biodrugs, Vol. 32 (september 2018) , p. 397-404  

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