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12 p, 613.3 KB |
One-Step Nucleic Acid Amplification (OSNA) of Sentinel Lymph Node in Early-Stage Endometrial Cancer : Spanish Multicenter Study (ENDO-OSNA)
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Diestro, María Dolores (Hospital Universitario La Paz (Madrid)) ;
Berjón, Alberto (Hospital Universitario La Paz) ;
Zapardiel, Ignacio (Hospital Universitario La Paz (Madrid)) ;
Yébenes, Laura (Hospital Universitario La Paz) ;
Ruiz, Irune (Hospital Universitario Donostia Osakidetza) ;
Lekuona, Arantza (Hospital Universitario Donostia Osakidetza) ;
Rezola, Marta (Hospital Universitario Donostia Osakidetza) ;
Jaunarena, Ibon (Hospital Universitario Donostia Osakidetza) ;
Siegrist, Jaime (Hospital Universitario La Paz) ;
Sánchez-Pastor, Margarita (Hospital Universitario La Paz) ;
Cuadra, María (OSI Araba Hospital Universitario) ;
Sagasta, Amaia (OSI Araba Hospital Universitario) ;
Guerra, Isabel (OSI Araba Hospital Universitario) ;
Lete, Luis I. (OSI Araba Hospital Universitario) ;
Roldán, Fernando (Hospital Clínico Universitario Lozano Blesa) ;
Marta, Carlo B. (Hospital Clínico Universitario Lozano Blesa) ;
Boillos, María J. (Hospital Clínico Universitario Lozano Blesa) ;
Cardiel, María J. (Hospital Clínico Universitario Lozano Blesa) ;
López-de la Manzanara, Carlos (Hospital General Universitario Ciudad Real) ;
Relea, Fernanda (Hospital General Universitario Ciudad Real) ;
Coronado, Pluvio (Hospital Clínico San Carlos (Madrid)) ;
Pascual, Alejandro (Hospital Clínico San Carlos (Madrid)) ;
Román, María J. (Hospital General Universitari Dr. Balmis) ;
Peiró, Gloria (Hospital General Universitari Dr. Balmis) ;
Matute, Luis J. (Hospital Universitari i Politècnic La Fe (València)) ;
Montero, Beatriz (Hospital Universitari i Politècnic La Fe (València)) ;
Muruzábal, Juan C. (Complejo Hospitalario Universitario Navarra) ;
Guarch, Rosa (Complejo Hospitalario Universitario Navarra) ;
Zorrero, Cristina (Hospital Fundación IVO) ;
Calatrava, Ana (Hospital Fundación IVO, 46009 Valencia) ;
Ribot, Laia (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Costa, Irmgard (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Hernández Gutierrez, Alicia (Hospital Universitario La Paz) ;
Hardisson, David (Hospital Universitario La Paz) ;
Universitat Autònoma de Barcelona
One-step nucleic acid amplification (OSNA) is an automated molecular diagnostic assay used to detect metastases by analyzing the levels of cytokeratin 19 mRNA in whole lymph nodes. It has been validated as an accurate and reliable tool for staging in several types of cancers and is included in the National Institute for Health and Care Excellence guidelines for the management of breast cancer. [...]
2021 -  10.3390/cancers13174465
Cancers, Vol. 13 (september 2021)
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2.
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13 p, 1.6 MB |
Mutational Profile Enables the Identification of a High-Risk Subgroup in Myelodysplastic Syndromes with Isolated Trisomy 8
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Toribio-Castelló, Sofía (CIBERONC. Research Group CB16/12/00233) ;
Castaño-Díez, Sandra (Hospital Clínic i Provincial de Barcelona) ;
Villaverde-Ramiro, Ángela (Universidad de Salamanca) ;
Such, Esperanza (Hospital Universitari i Politècnic La Fe (València)) ;
Arnan, Montserrat (Hospital Duran i Reynals (Hospitalet del Llobregat)) ;
Sole, F (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Díaz-Beyá, Marina (Hospital Clínic i Provincial de Barcelona) ;
Díez-Campelo, María (CIBERONC. Research Group CB16/12/00233) ;
del Rey, Mónivs (Hospital Universitario de Salamanca) ;
González, Teresa (Hospital Universitario de Salamanca) ;
Hernández-Rivas, Jesús María (CIBERONC. Research Group CB16/12/00233)
Trisomy 8 (+8) is the most frequent trisomy in myelodysplastic syndromes (MDS) and is associated with clinical heterogeneity and intermediate cytogenetic risk when found in isolation. The presence of gene mutations in this group of patients and the prognostic significance has not been extensively analyzed. [...]
2023 - 10.3390/cancers15153822
Cancers, Vol. 15 Núm. 15 (august 2023) , p. 3822
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3.
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12 p, 801.4 KB |
The Secondary Myelodysplastic Neoplasms (MDS) Jigsaw
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Calvete, Oriol (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Mestre, Julia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Jerez, Andrés (Vall d'Hebron Institut d'Oncologia) ;
Sole, F (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
There is a great deal of controversy in the hematologic community regarding the classification of secondary myelodysplastic neoplasms (MDSs). Current classifications are based on the presence of genetic predisposition and MDS post-cytotoxic therapy (MDS-pCT) etiologies. [...]
2023 - 10.3390/cancers15051483
Cancers, Vol. 15 Núm. 5 (march 2023) , p. 1483
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4.
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32 p, 5.0 MB |
Childhood and Adolescent Central Nervous System Tumours in Spain : Incidence and Survival over 20 Years: A Historical Baseline for Current Assessment
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Chirlaque, María D. (Universidad de Murcia. Departamento de Epidemiología) ;
Peris-Bonet, Rafael (Spanish Registry of Childhood Tumours. University of Valencia) ;
Sánchez, Antonia (Department of Epidemiology. Murcia Regional Health Authority) ;
Cruz, Ofelia (Hospital Sant Joan de Déu (Manresa)) ;
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Gutiérrez-Ávila, Gonzalo (Castile-La Mancha Cancer Registry) ;
Quirós-García, José R. (Asturias Cancer Registry. Public Health Directorate) ;
Almela-Vich, Fernando (Valencian Regional Childhood Cancer Registry) ;
López de Munain, Arantza (Basque Country Cancer Registry) ;
Sánchez, María J. (Granada Bio-Health Research Institute) ;
Franch-Sureda, Paula (Mallorca Cancer Registry. Balearic Isles Health Research Institute) ;
Ardanaz, Eva (Navarre Health Research Institute) ;
Galceran, Jaume (Universitat Rovira i Virgili) ;
Martos, Carmen (Foundation for the Promotion of Health and Biomedical Research in the Valencian Region) ;
Salmerón, Diego (Universidad de Murcia. Department of Health and Social Sciences) ;
Gatta, Gemma (Fondazione IRCCS Istituto Nazionale dei Tumori di Milano) ;
Botta, Laura (Istituto Nazionale dei Tumori) ;
Cañete, Adela (Universitat de València)
Background: Central nervous system (CNS) neoplasms are highly frequent solid tumours in children and adolescents. While some studies have shown a rise in their incidence in Europe, others have not. Survival remains limited. [...]
2023 - 10.3390/cancers15245889
Cancers, Vol. 15 Núm. 24 (december 2023) , p. 5889
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13 p, 1.8 MB |
Lymph Node Molecular Analysis with OSNA Enables the Identification of pT1 CRC Patients at Risk of Recurrence : A Multicentre Study
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Saez de Gordoa, Karmele (Hospital Clínic i Provincial de Barcelona) ;
Rodrigo-Calvo, Maria Teresa (Hospital Clínic i Provincial de Barcelona) ;
Archilla, Ivan (Hospital Clínic i Provincial de Barcelona) ;
Lopez-Prades, Sandra (Hospital Clínic i Provincial de Barcelona) ;
Díaz, Alba (Hospital Clínic i Provincial de Barcelona) ;
Tarragona, Jordi (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Machado, Isidro (Centro de Investigación Biomédica en Red en Cancer (CIBERONC)) ;
Ruiz Martín, Juan (Virgen de la Salud Hospital, Toledo) ;
Zaffalon, Diana (Consorci Sanitari de Terrassa) ;
Daca-Alvarez, Maria (Hospital Clínic i Provincial de Barcelona) ;
Pellisé, Maria (Hospital Clínic i Provincial de Barcelona) ;
Camps, Jordi (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Cuatrecasas, Miriam (Hospital Clínic i Provincial de Barcelona)
Early-stage colorectal carcinoma (CRC)-pT1-is a therapeutic challenge and presents some histological features related to lymph node metastasis (LNM). A significant proportion of pT1 CRCs are treated surgically, resulting in a non-negligible surgical-associated mortality rate of 1. [...]
2023 - 10.3390/cancers15225481
Cancers, Vol. 15 (november 2023)
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55 p, 707.1 KB |
Advances in the Use of Deep Learning for the Analysis of Magnetic Resonance Image in Neuro-Oncology
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Pitarch, Carla (Universitat Politècnica de Catalunya. Departament d'Informàtica) ;
Ungan, Gulnur Semahat (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Julià Sapé, Ma. Margarita (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Vellido, Alfredo (Universitat Politècnica de Catalunya. Departament d'Informàtica)
Machine Learning is entering a phase of maturity, but its medical applications still lag behind in terms of practical use. The field of oncological radiology (and neuro-oncology in particular) is at the forefront of these developments, now boosted by the success of Deep-Learning methods for the analysis of medical images. [...]
2024 - 10.3390/cancers16020300
Cancers, Vol. 16, Issue 2 (January 2024) , art. 300
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18 p, 4.4 MB |
TP53 Abnormalities Are Underlying the Poor Outcome Associated with Chromothripsis in Chronic Lymphocytic Leukemia Patients with Complex Karyotype
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Ramos-Campoy, Silvia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Kamaso, Joanna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Beà, Sílvia (Centro de Investigación Biomédica en Red de Cáncer) ;
Bougeon, Sandrine (Lausanne University Hospital) ;
Larráyoz, María José (Universidad Pública de Navarra) ;
Costa, Dolors (Centro de Investigación Biomédica en Red de Cáncer) ;
Parker, Helen (University of Southampton) ;
Rigolin, Gian Matteo (St. Anna University Hospital) ;
Blanco, María Laura (Institut d'Investigació Biomèdica Sant Pau) ;
Collado, Rosa (Consorcio Hospital General Universitario) ;
Ancín, Idoya (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Salgado, Rocío (Fundación Jiménez Díaz) ;
Moro-García, Marco A. (Hospital Universitario Central de Asturias) ;
Baumann, Tycho (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Gimeno, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Moreno, Carol (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Salido, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Calvo, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Calasanz, M.J (Universidad Pública de Navarra) ;
Cuneo, Antonio (Hematology Section. St. Anna University Hospital) ;
Nguyen-Khac, Florence (Sorbonne University) ;
Oscier, David (Royal Bournemouth Hospital) ;
Haferlach, Claudia (MLL Munich Leukemia Laboratory) ;
Strefford, Jonathan C (University of Southampton) ;
Schoumans, Jacqueline (Lausanne University Hospital) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Universitat Autònoma de Barcelona
Chromothripsis (cth) has been associated with a dismal outcome and poor prognosis factors in patients with chronic lymphocytic leukemia (CLL). Despite being correlated with high genome instability, previous studies have not assessed the role of cth in the context of genomic complexity. [...]
2022 - 10.3390/cancers14153715
Cancers, Vol. 14 Núm. 15 (august 2022) , p. 3715
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11 p, 1.2 MB |
Correlation of recist, computed tomography morphological response, and pathological regression in hepatic metastasis secondary to colorectal cancer : The avamet study
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Vera, Ruth (Instituto de investigaciones Sanitarias de Navarra (IdISNA)) ;
Gómez, María Luisa (Complejo Hospitalario de Navarra) ;
Ayuso Colella, Juan Ramón (Hospital Clínic i Provincial de Barcelona) ;
Figueras, Joan (Hospital Universitari de Girona Doctor Josep Trueta) ;
García-Alfonso, Pilar (Hospital General Universitario Gregorio Marañón) ;
Martínez, Virginia (Hospital Universitario La Paz (Madrid)) ;
Lacasta, Adelaida (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Ruiz-casado, Ana (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Safont, María José (Hospital General Universitario de Valencia) ;
Aparicio Urtasun, Jorge (Hospital Universitari i Politècnic La Fe (València)) ;
Campos, Juan Manuel (Hospital Arnau de Vilanova (València)) ;
Cámara, Juan Carlos (Hospital Universitario Fundación Alcorcón) ;
Martín-Richard, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Montagut Viladot, Clara (Hospital del Mar (Barcelona, Catalunya)) ;
Pericay, Carles (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Vieitez, Jose María (Hospital Universitario Central de Asturias) ;
Falcó, Esther (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
Jorge, Mónica (Hospital Xeral Cíes) ;
Marín, Miguel (Hospital Clínico Universitario de la Arrixaca) ;
Salgado, Mercedes (Complejo Hospitalario de Ourense) ;
Viúdez, Antonio (Instituto de investigaciones Sanitarias de Navarra (IdISNA)) ;
Universitat Autònoma de Barcelona
The prospective phase IV AVAMET study was undertaken to correlate response evaluation criteria in solid tumors (RECIST)-defined response rates with computed tomography-based morphological criteria (CTMC) and pathological response after liver resection of colorectal cancer metastases. [...]
2020 - 10.3390/cancers12082259
Cancers, Vol. 12 Núm. 8 (august 2020) , p. 1-12
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16 p, 1.2 MB |
Hereditary leiomyomatosis and renal cell cancer syndrome in spain : Clinical and genetic characterization
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Sánchez-Heras, A.Beatriz (Hospital General Universitario de Elche) ;
Castillejo, Adela (Hospital General Universitario de Elche) ;
García-Díaz, Juan D. (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Robledo, Mercedes (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Teulé, Alexandre (Hospital Universitari de Bellvitge) ;
Sánchez, Rosario (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Zúñiga, Ángel (Hospital Universitari i Politècnic La Fe (València)) ;
Lastra, Enrique (Hospital Universitario de Burgos) ;
Durán, Mercedes (Instituto de Biología y Genética Molecular (IBGM-UVA-CSIC)) ;
Llort, Gemma (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Yagüe, Carmen (Consorci Sanitari de Terrassa) ;
Ramon y Cajal, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
López San Martin, Consol (Institut d'Investigació Biomèdica Sant Pau) ;
López-Fernández, Adrià (Hospital Universitari Vall d'Hebron) ;
Balmaña Gelpí, Judith (Hospital Universitari Vall d'Hebron) ;
Robles, Luis (Hospital 12 de Octubre (Madrid)) ;
Mesa-Latorre, José M. (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Chirivella, Isabel (Universitat de València) ;
Fonfria, María (Consorci Hospitalari Provincial de Castelló) ;
Ibañez, Raquel Perea (Hospital General Universitario de Elche) ;
Castillejo, M.Isabel (Hospital General Universitario de Elche) ;
Escandell, Inés (Hospital General Universitario de Elda) ;
Gomez, Luis (Hospital Universitario Sant Joan de Alicante) ;
Berbel, Pere (Universidad Miguel Hernández de Elche) ;
Soto, Jose Luis (Hospital General Universitario de Elche) ;
Universitat Autònoma de Barcelona
Hereditary leiomyomatosis and renal cell cancer syndrome (HLRCC) is a very rare hereditary disorder characterized by cutaneous leiomyomas (CLMs), uterine leiomyomas (ULMs), renal cysts (RCys) and renal cell cancers (RCCs). [...]
2020 - 10.3390/cancers12113277
Cancers, Vol. 12 Núm. 11 (november 2020) , p. 1-16
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20 p, 3.4 MB |
Consensus definition and prediction of complexity in transurethral resection or bladder endoscopic dissection of bladder tumours
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Roumiguié, Mathieu (Institut Universitaire du Cancer) ;
Xylinas, Evanguelos (Hôpital Cochin) ;
Brisuda, Antonin (Charles University) ;
Burger, Maximillian (St. Josef. Klinik für Urologie) ;
Mostafid, Hugh (Royal Surrey County Hospital) ;
Colombel, Marc (Hôpital Edouard Herriot) ;
Babjuk, Marek (Charles University) ;
Palou, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Witjes, Fred (Radboud UMC) ;
Malavaud, Bernard (Institut Universitaire du Cancer) ;
Universitat Autònoma de Barcelona
Ten senior urologists were interrogated to develop a predictive model based on factors from which they could anticipate complex transurethral resection of bladder tumours (TURBT). Complexity was defined by consensus. [...]
2020 - 10.3390/cancers12103063
Cancers, Vol. 12 Núm. 10 (october 2020) , p. 1-21
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