Depósito Digital de Documentos de la UAB Encontrados 10 registros  La búsqueda tardó 0.01 segundos. 
1.
13 p, 23.3 MB Increased PARP Activity and DNA Damage in NSCLC Patients : influence of COPD / Tang, Jun (Institut Hospital del Mar d'Investigacions Mèdiques) ; Curull Serrano, Víctor (Institut Hospital del Mar d'Investigacions Mèdiques) ; Wang, Xuejie (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ampurdanés, Coral (Institut Hospital del Mar d'Investigacions Mèdiques) ; Duran, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ; Pijuan, Lara (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rodríguez-Fuster, Alberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Aguiló, Rafael (Institut Hospital del Mar d'Investigacions Mèdiques) ; Yélamos, Jose (Institut Hospital del Mar d'Investigacions Mèdiques) ; Barreiro, Esther (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona
(1) Background: Lung cancer (LC) is a major leading cause of death worldwide. Poly (ADP-ribose) polymerase (PARP)-1 and PARP-2 are key players in cancer. We aimed to assess PARP-1 and PARP-2 expression and activity and DNA damage in tumors and non-tumor lungs from patients with/without chronic obstructive pulmonary disease (COPD). [...]
2020 - 10.3390/cancers12113333
Cancers, Vol. 12 Núm. 11 (2020) , p. 3333  
2.
20 p, 4.5 MB TSPAN1 : a Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance / Garcia Mayea, Yoelsis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Mir, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Carballo, Laia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Castellvi, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Temprana-Salvador, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lorente, Juan (Hospital Universitari Vall d'Hebron) ; Benavente, Sergi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García-Pedrero, Juana M. (Centro de Investigación Biomédica en Red Cáncer (CIBERONC)) ; Allonca, Eva (Centro de Investigación Biomédica en Red Cáncer (CIBERONC)) ; Rodrigo, Juan P. (Centro de Investigación Biomédica en Red Cáncer (CIBERONC)) ; LLeonart, Matilde E. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Sensitization of resistant cells and cancer stem cells (CSCs) represents a major challenge in cancer therapy. A proteomic study revealed tetraspanin-1 (TSPAN1) as a protein involved in acquisition of cisplatin (CDDP) resistance (Data are available via ProteomeXchange with identifier PXD020159). [...]
2020 - 10.3390/cancers12113269
Cancers, Vol. 12 Núm. 11 (2020) , p. 3269  
3.
25 p, 4.2 MB Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells / Tishchenko, Alexander (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Azorín, Daniel D. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vidal-Brime, Laia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; José Muñoz, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Jiménez Arenas, Pol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pearce, Christopher (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Girao, Henrique (University of Coimbra. Faculty of Medicine) ; Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Aasen, Trond (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Connexin 43 (Cx43) forms gap junctions that mediate the direct intercellular diffusion of ions and small molecules between adjacent cells. Cx43 displays both pro- and anti-tumorigenic properties, but the mechanisms underlying these characteristics are not fully understood. [...]
2020 - 10.3390/cancers12102798
Cancers, Vol. 12 Núm. 10 (2020) , p. 2798  
4.
17 p, 2.7 MB B Cells and Tertiary Lymphoid Structures Influence Survival in Lung Cancer Patients with Resectable Tumors / Tang, Jun (Institut Hospital del Mar d'Investigacions Mèdiques) ; Curull Serrano, Víctor (Institut Hospital del Mar d'Investigacions Mèdiques) ; Wang, Xuejie (Institut Hospital del Mar d'Investigacions Mèdiques) ; Mateu-Jiménez, Mercé (Institut Hospital del Mar d'Investigacions Mèdiques) ; Pijuan, Lara (Institut Hospital del Mar d'Investigacions Mèdiques) ; Duran, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ; Qin, Liyun (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rodríguez-Fuster, Alberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Aguiló, Rafael (Institut Hospital del Mar d'Investigacions Mèdiques) ; Barreiro, Esther (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ramis-Cabrer, Daniel (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona
Immune profile of B and T cells and tertiary lymphoid structures (TLSs) may differ in tumors of lung cancer (LC) patients with/without chronic obstructive pulmonary disease (COPD), and may also influence patient survival. [...]
2020 - 10.3390/cancers12092644
Cancers, Vol. 12 Núm. 9 (2020) , p. 2644  
5.
17 p, 2.5 MB Implication of Voltage-Gated Potassium Channels in Neoplastic Cell Proliferation / Serrano-Novillo, Clara (Molecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Avda. Diagonal 643, E-08028 Barcelona, Spain; (C.S.-N.); (J.C.); (M.C.-M.)) ; Capera, Jesusa (Molecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Avda. Diagonal 643, E-08028 Barcelona, Spain; (C.S.-N.); (J.C.); (M.C.-M.)) ; Colomer-Molera, Magalí (Molecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Avda. Diagonal 643, E-08028 Barcelona, Spain; (C.S.-N.); (J.C.); (M.C.-M.)) ; Condom, Enric (Departament de Patologia i Terapèutica Experimental, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de Llobregat, 08907 Barcelona, Spain) ; Ferreres, Joan Carles (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ; Felipe, Antonio (Molecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Avda. Diagonal 643, E-08028 Barcelona, Spain; (C.S.-N.); (J.C.); (M.C.-M.))
Voltage-gated potassium channels (Kv) are the largest group of ion channels. Kv are involved in controlling the resting potential and action potential duration in the heart and brain. Additionally, these proteins participate in cell cycle progression as well as in several other important features in mammalian cell physiology, such as activation, differentiation, apoptosis, and cell volume control. [...]
2019 - 10.3390/cancers11030287
Cancers, Vol. 11 (march 2019)  
6.
Ev-associated miRNAs from peritoneal lavage are a source of biomarkers in endometrial cancer / Roman-Canal, B. (Universitat Autònoma de Barcelona) ; Moiola, C.P. (Biomedical Research Group in Gynecology. Vall Hebron Research Institute (VHIR). CIBERONC) ; Gatius, S. (Department of Pathology and Molecular Genetics/Oncologic Pathology Group. Biomedical Research Institute of Lleida (IRBLleida). University of Lleida. CIBERONC) ; Bonnin, S. (Centre for Genomic Regulation (CRG). The Barcelona Institute or Science and Technology) ; Ruiz-Miró, M. (Department of Pathology and Molecular Genetics/Oncologic Pathology Group. Biomedical Research Institute of Lleida (IRBLleida). University of Lleida. CIBERONC) ; González, E. (Exosomes Laboratory and Metabolomics Platform. CIC bioGUNE. CIBEREHD Bizkaia Technology Park) ; González-Tallada, X. (Department of Pathology and Molecular Genetics/Oncologic Pathology Group. Biomedical Research Institute of Lleida (IRBLleida). University of Lleida. CIBERONC) ; Llordella, I. (Department of Pathology and Molecular Genetics/Oncologic Pathology Group. Biomedical Research Institute of Lleida (IRBLleida). University of Lleida. CIBERONC) ; Hernández, Isabel (Department of Pathology and Molecular Genetics/Oncologic Pathology Group. Biomedical Research Institute of Lleida (IRBLleida). University of Lleida. CIBERONC) ; Porcel, J.M. (Pleural Medicine Unit. Arnau de Vilanova University Hospital. Cancer Biomarker Group. IRBLleida) ; Gil-Moreno, A. (Gynecological Oncology Department. Vall Hebron University Hospital. CIBERONC) ; Falcón-Pérez, J.M. (IKERBASQUE. Basque Foundation for Science) ; Ponomarenko, J. (Universitat Pompeu Fabra) ; Matias-Guiu, X. (Department of Pathology. University Hospital of Bellvitge. Bellvitge Biomedical Research Institute (IDIBELL)) ; Colas, E. (Biomedical Research Group in Gynecology. Vall Hebron Research Institute (VHIR). CIBERONC) ; Universitat Autònoma de Barcelona. Departament de Medicina
Endometrial cancer (EC) is the sixth most common cancer in women worldwide and is responsible for more than 89,000 deaths every year. Mortality is associated with presence of poor prognostic factors at diagnosis, i. [...]
2019 - 10.3390/cancers11060839
Cancers, Vol. 11 Núm. 6 (2019) , p. 839  
7.
19 p, 2.6 MB Pharmacological modulation of SAMHD1 activity by CDK4/6 inhibitors improves anticancer therapy / Castellví, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Felip, Eudald (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ezeonwumelu, Ifeanyi Jude (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Badia, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Garcia-Vidal, Edurne (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pujantell, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Gutiérrez-Chamorro, Lucía (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Teruel, Iris (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Riveira-Muñoz, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Margelí, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ballana, Ester (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
Sterile alpha motif and histidine-aspartic acid domain-containing protein 1 (SAMHD1) is a dNTP triphosphohydrolase involved in the regulation of the intracellular dNTP pool, linked to viral restriction, cancer development and autoimmune disorders. [...]
2020 - 10.3390/cancers12030713
Cancers, Vol. 12 Núm. 3 (march 2020) , p. 713  
8.
19 p, 1.1 MB Pharmacological targeting of bet bromodomain proteins in acute myeloid leukemia and malignant lymphomas : From molecular characterization to clinical applications / Reyes-Garau, D. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ribeiro, Marcelo Lima (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roué, G. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
A25in25proarENG-pr910210011and DNA-protein interactions and abnormal chromatin remodeling are a major cause of uncontrolled gene transcription and constitutive activation of critical signaling pathways in cancer cells. [...]
2019 - 10.3390/cancers11101483
Cancers, Vol. 11 Núm. 10 (october 2019) , p. 1483  
9.
16 p, 3.3 MB Immunotherapy with monoclonal antibodies in lung cancer of mice : oxidative stress and other biological events / Barreiro, E. (Health and Experimental Sciences Department (CEXS). Pompeu Fabra University (UPF). Biomedical Research Park (PRBB)) ; Tang, J. (Universitat Autònoma de Barcelona. Departament de Medicina) ; Ramis-Cabrer, Daniel. (Health and Experimental Sciences Department (CEXS). Pompeu Fabra University (UPF). Biomedical Research Park (PRBB)) ; Wang, X. (Universitat Autònoma de Barcelona. Departament de Medicina)
Background: Lung cancer (LC) is a major leading cause of death worldwide. Immunomodulators that target several immune mechanisms have proven to reduce tumor burden in experimental models through induction of the immune microenvironment. [...]
2019 - 10.3390/cancers11091301
Cancers, Vol. 11 Núm. 9 (september 2019) , p. 1301  
10.
25 p, 1.1 MB Post-Translational Modifications of H2A Histone Variants and Their Role in Cancer / Corujo, David (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Histone variants are chromatin components that replace replication-coupled histones in a fraction of nucleosomes and confer particular characteristics to chromatin. H2A variants represent the most numerous and diverse group among histone protein families. [...]
2018 - 10.3390/cancers10030059
Cancers, Vol. 10 (february 2018)  

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