Depósito Digital de Documentos de la UAB Encontrados 38 registros  1 - 10siguientefinal  ir al registro: La búsqueda tardó 0.00 segundos. 
1.
20 p, 1.0 MB Pentafecta for Radical Nephroureterectomy in Patients with High-Risk Upper Tract Urothelial Carcinoma : A Proposal for Standardization of Quality Care Metrics / König, Frederik (University Medical Center Hamburg-Eppendorf, Hamburg, Germany) ; Grossmann, Nico C. (Luzerner Kantonsspital, Lucerne, Switzerland) ; Soria, Francesco (San Giovanni Battista Hospital) ; D'Andrea, David (Medical University of Vienna, Vienna, Austria) ; Juvet, Tristan (Lions Gate Hospital, North Vancouver, Canada) ; Potretzke, Aaron (Mayo Clinic, Rochester, USA) ; Djaladat, Hooman (USC/Norris Comprehensive Cancer Center, Los Angeles, USA) ; Ghoreifi, Alireza (USC/Norris Comprehensive Cancer Center, Los Angeles, USA) ; Kikuchi, Eiji (St. Marianna University School of Medicine, Kawasaki, Japan) ; Hayakawa, Nozomi (St. Marianna University School of Medicine, Kawasaki, Japan) ; Mari, Andrea (Unit of Oncologic Minimally-Invasive Urology and Andrology, Florence, Italy) ; Khene, Zine-Eddine (University of Rennes, Rennes, France) ; Fujita, Kazutoshi (Kindai University, Osaka, Japan) ; Raman, Jay D. (The Pennsylvania State University, Hershey, USA) ; Breda, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Fontana, Matteo (Institut d'Investigació Biomèdica Sant Pau) ; Sfakianos, John P. (Icahn School of Medicine at Mount Sinai, New York, USA) ; Pfail, John L. (Icahn School of Medicine at Mount Sinai, New York, USA) ; Laukhtina, Ekaterina (Sechenov University, Moscow, Russia) ; Rajwa, Pawel (Medical University of Silesia, Zabrze, Poland) ; Pallauf, Maximilian (University Hospital Salzburg, Salzburg, Austria) ; Cacciamani, Giovanni E. (University of Southern California, Los Angeles, USA) ; van Doeveren, Thomas (University Medical Center, Rotterdam, The Netherlands) ; Boormans, Joost L. (University Medical Center, Rotterdam, The Netherlands) ; Antonelli, Alessandro (University of Verona, Verona, Italy) ; Jamil, Marcus (Henry Ford Hospital, Detroit, USA) ; Abdollah, Firas (Henry Ford Hospital, Detroit, USA) ; Budzyn, Jeffrey (Henry Ford Hospital, Detroit, USA) ; Ploussard, Guillaume (La Croix du Sud Hospital, Toulouse, France) ; Heidenreich, Axel (University Hospital Cologne, Cologne Germany) ; Daneshmand, Siamak (USC/Norris Comprehensive Cancer Center, Los Angeles, USA) ; Boorjian, Stephen A. (Mayo Clinic, Rochester, USA) ; Rouprêt, Morgan (Sorbonne University, Paris, France) ; Rink, Michael (University Medical Center Hamburg-Eppendorf, Hamburg, Germany) ; Shariat, Shahrokh F. (Charles University, Prague, Czech Republic) ; Pradere, Benjamin (La Croix du Sud Hospital, Toulouse, France) ; Universitat Autònoma de Barcelona
Measuring the quality of care is important in health care to improve the treatment of patients. In this investigation, we sought to identify five indicators ("pentafecta") that reflect the quality of care of patients who have cancer of the upper urinary tract (kidney and/or ureter) and are treated with surgical removal of the affected kidney and ureter. [...]
2022 - 10.3390/cancers14071781
Cancers, Vol. 14 (march 2022)  
2.
16 p, 1.6 MB Phase 2 Trial (POLA Study) of Lurbinectedin plus Olaparib in Patients with Advanced Solid Tumors : Results of Efficacy, Tolerability, and the Translational Study / Poveda, Andres (Hospital Quironsalud (Valencia). Oncogynecologic Department) ; Lopez-Reig, Raquel (Fundació Institut Valencià d'Oncologia) ; Oaknin, Ana (Vall d'Hebron Institut d'Oncologia) ; Redondo, Andres (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ; Rubio, Maria Jesus (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ; Guerra, Eva (Hospital Universitario Ramón y Cajal (Madrid)) ; Fariñas-Madrid, Lorena (Vall d'Hebron Institut d'Oncologia) ; Gallego, Alejandro (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ; Rodriguez-Freixinos, Victor (Vall d'Hebron Institut d'Oncologia) ; Fernandez-Serra, Antonio (Fundació Institut Valencià d'Oncologia) ; Juan, Oscar (Pivotal SLU (Madrid)) ; Romero, Ignacio (Fundació Institut Valencià d'Oncologia) ; Lopez-Guerrero, Jose A. (Fundació Institut Valencià d'Oncologia)
Genomic instability (GI) is a transversal phenomenon in oncology, constituting a hallmark of cancer. In gynecological malignancies, the predictive value of GI has been described and is mainly caused by alterations in the homologous recombination repair (HRR) genes, such as BRCA1/2. [...]
2022 - 10.3390/cancers14040915
Cancers, Vol. 14 Núm. 4 (february 2022)  
3.
19 p, 3.2 MB Glioblastoma Cells Counteract PARP Inhibition through Pro-Survival Induction of Lipid Droplets Synthesis and Utilization / Majuelos-Melguizo, Jara (Universidad Autónoma de Madrid. Departamento de Bioquímica) ; Rodríguez-Vargas, José Manuel (Instituto de Parasitología y Biomedicina "López-Neyra") ; Martínez-López, Nuria (Newcastle University. Institute for Cell and Molecular Biosciences) ; Delgado-Bellido, Daniel (Instituto de Parasitología y Biomedicina "López-Neyra") ; García-Díaz, Ángel (Instituto de Parasitología y Biomedicina "López-Neyra") ; Yuste, Vi­ctor J (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; García-Macía, Marina (Newcastle University. Institute of Cellular Medicine) ; López, Laura M. (Instituto de Parasitología y Biomedicina "López-Neyra") ; Singh, Rajat (Albert Einstein College of Medicine. Department of Molecular Pharmacology) ; Oliver, F. J. (Instituto de Parasitología y Biomedicina "López-Neyra") ; Universitat Autònoma de Barcelona. Institut de Neurociències
Glioblastoma multiforme (GBM) is the most common and deadly primary brain tumor in adults and one of the most aggressive cancers. The use of Poly ADP-Ribose Polymerase (PARP) inhibitors is being expanded as therapeutic alternative in multiple types of cancer beyond BRCA1/2 mutant breast and ovarian cancer. [...]
2022 - 10.3390/cancers14030726
Cancers, Vol. 14 Núm. 3 (january 2022)  
4.
20 p, 1.9 MB Modulation of DNA Damage Response by SAM and HD Domain Containing Deoxynucleoside Triphosphate Triphosphohydrolase (SAMHD1) Determines Prognosis and Treatment Efficacy in Different Solid Tumor Types / Felip, Eudald (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gutiérrez-Chamorro, Lucía (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Gómez, Maica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; García Vidal, Edurne (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Romeo, Margarita (Universitat Autònoma de Barcelona. Departament de Medicina) ; Morán, Teresa (Universitat Autònoma de Barcelona. Departament de Medicina) ; Layos, Laura (Universitat Autònoma de Barcelona. Departament de Medicina) ; Pérez-Roca, Laia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Riveira-Muñoz, Eva (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Fernandez, Pedro Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mesía, Ricard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ballana, Ester (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Margelí, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Ample evidence exists connecting dNTP pool dysregulation to cancer and genomic instability. SAMHD1, the unique dNTP triphosphohydrolase described in humans, has been proposed to play a key role in hematological cancers, although its value in advanced solid tumors has not yet been explored. [...]
2022 - 10.3390/cancers14030641
Cancers, Vol. 14 Núm. 3 (january 2022)  
5.
19 p, 1.6 MB Update on Management Recommendations for Advanced Cutaneous Squamous Cell Carcinoma / García-Foncillas, Jesús (Universidad Autónoma de Madrid. Departamento de Medicina) ; Tejera-Vaquerizo, Antonio (Hospital San Juan de Dios (Còrdova, Espanya)) ; Sanmartín, Onofre (Fundació Institut Valencià d'Oncologia) ; Rojo, Federico (Hospital Universitario Fundación Jiménez Díaz) ; Mestre, Javier (Hospital Universitario Miguel Servet (Saragossa)) ; Martín, Salvador (Clínica Universitaria de Navarra) ; Azinovic, Ignacio (Hospital Universitario Fundación Jiménez Díaz) ; Mesía, Ricard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer, which predominantly occurs on the head and neck. Early detection and treatment of primary tumours is crucial to limit progression and local invasion of deep tissues. [...]
2022 - 10.3390/cancers14030629
Cancers, Vol. 14 Núm. 3 (january 2022)  
6.
16 p, 1.7 MB Succinate Pathway in Head and Neck Squamous Cell Carcinoma : Potential as a Diagnostic and Prognostic Marker / Terra, Ximena (Universitat Rovira i Virgili) ; Ceperuelo-Mallafré, Victoria (CIBERDEM) ; Merma Linares, Carla Vanessa (Universitat Rovira i Virgili) ; Benaiges Moragrega, Ester (Universitat Rovira i Virgili) ; Bosch Príncep, Ramon (Hospital de Tortosa Verge de la Cinta) ; Castillo, Paola (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Flores, Joan Carles (Universitat Rovira i Virgili) ; León, Xavier (Institut d'Investigació Biomèdica Sant Pau) ; Valduvieco, Izaskun (Hospital Clínic i Provincial de Barcelona) ; Basté, Neus (Hospital Clínic i Provincial de Barcelona) ; Cámara, Marina (Hospital Clínic i Provincial de Barcelona) ; Lejeune, Marylène (Hospital de Tortosa Verge de la Cinta) ; Gumà, Josep (Institut d'Investigació Sanitària Pere Virgili) ; Vendrell, Joan (Universitat Rovira i Virgili) ; Vilaseca, Isabel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Fernández-Veledo, Sonia (CIBERDEM) ; Avilés-Jurado, Francesc Xavier (Hospital Clínic i Provincial de Barcelona) ; Universitat Autònoma de Barcelona
Emerging evidence points to succinate as an important oncometabolite in cancer development; however, the contribution of the succinate-SUCNR1 axis to cancer progression remains unclear. Head and neck squamous cell carcinoma (HNSCC) is associated with disease and treatment-related morbidity so there is an urgent need for innovation in treatment and diagnosis practices. [...]
2021 - 10.3390/cancers13071653
Cancers, Vol. 13 (april 2021)  
7.
22 p, 6.0 MB ARMCX3 Mediates Susceptibility to Hepatic Tumorigenesis Promoted by Dietary Lipotoxicity / Mirra, Serena (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Gavaldà-Navarro, Aleix (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ; Manso, Yasmina (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Higuera, Mónica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Serrat, Román (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Salcedo, María Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Burgaya, Ferran (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Balibrea, José María (Hospital Universitari Vall d'Hebron) ; Santamaría Monasterio, Eva (Universidad de Navarra) ; Uriarte, Iker (Universidad de Navarra) ; Berasain, Carmen (Universidad de Navarra) ; Avila, Matias A. (Universidad de Navarra) ; Mínguez Rosique, Beatriz (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Soriano, Eduardo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Villarroya, Francesc (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ; Universidad Autònoma de Barcelona
An excess fat in the liver enhances the susceptibility to hepatic cancer. We found that Armcx3, a protein only known to date to play a role in neural development, is strongly increased in mouse liver in response to lipid availability and proliferation-inducing insults. [...]
2021 - 10.3390/cancers13051110
Cancers, Vol. 13 (march 2021)  
8.
17 p, 5.3 MB Stimuli-Responsive Hydrogels for Cancer Treatment : The Role of pH, Light, Ionic Strength and Magnetic Field / Andrade, Fernanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roca-Melendres, Maria Mercé (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Durán-Lara, Esteban F. (Universidad de Talca) ; Rafael, Diana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Schwartz, Simon (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Cancer remains as the world second leading cause of death. The severe side effects associated to high doses of chemotherapy and the development of drug resistance are major drawbacks for a successful cancer treatment. [...]
2021 - 10.3390/cancers13051164
Cancers, Vol. 13 (march 2021)  
9.
12 p, 1.2 MB Evolution of Angiogenic Factors in Pregnant Patients with Breast Cancer Treated with Chemotherapy / Saura, Cristina (Vall d'Hebron Institut d'Oncologia) ; Sánchez, Olga (Vall d'Hebron Institut d'Oncologia) ; Martínez, Sandra (Vall d'Hebron Institut d'Oncologia) ; Domínguez, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Dienstmann, Rodrigo (Vall d'Hebron Institut d'Oncologia) ; Ruíz-Pace, Fiorella (Vall d'Hebron Institut d'Oncologia) ; Céspedes, Maria Concepció (Hospital Universitari Vall d'Hebron) ; Peñuelas, Ángeles (Vall d'Hebron Institut d'Oncologia) ; Cortés, Javier (Vall d'Hebron Institut d'Oncologia) ; Llurba, E (Institut d'Investigació Biomèdica Sant Pau) ; Córdoba, Octavi (Institut d'Investigació Sanitària de les Illes Balears) ; Universitat Autònoma de Barcelona
Anthracyclines and taxanes are being used as a standard treatment for breast cancer diagnosed during pregnancy. These chemotherapy regimens allow the continuation of pregnancy without delaying cancer treatment with relatively good maternal and neonatal outcomes. [...]
2021 - 10.3390/cancers13040923
Cancers, Vol. 13 (february 2021)  
10.
15 p, 2.5 MB CDK5RAP3, a New BRCA2 Partner That Regulates DNA Repair, Is Associated with Breast Cancer Survival / Minguillón Pedreño, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Ramírez de Haro, Ma. José (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Rovirosa Mulet, Llorenç (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Bustamante-Madrid, Pilar (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Camps-Fajol, Cristina (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; de Garibay, Gorka Ruiz (Institut Català d'Oncologia) ; Shimelis, Hermela (Mayo Clinic) ; Montanuy Escribano, Helena (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Pujol, Roser (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Hernandez, Gonzalo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Bogliolo, Massimo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Castillo, Pau (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Soucy, Penny (Centre Hospitalier Universitaire de Québec Research Center and Laval University) ; Martrat, Griselda (Institut Català d'Oncologia) ; Gómez Moruno, Antonio (Institut d'Investigació Biomèdica de Bellvitge) ; Cuadras, Daniel (Institut Català d'Oncologia) ; García, Maria J. (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ; Gayarre, Javier (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ; Lázaro Garcia, Conxi (Institut Català d'Oncologia) ; Benítez, Javier (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ; Couch, Fergus J. (Mayo Clinic) ; Pujana, Miquel Ángel (Institut Català d'Oncologia) ; Surrallés i Calonge, Jordi (Institut d'Investigació Biomèdica Sant Pau)
BRCA2 is essential for homologous recombination DNA repair. BRCA2 mutations lead to genome instability and increased risk of breast and ovarian cancer. Similarly, mutations in BRCA2-interacting proteins are also known to modulate sensitivity to DNA damage agents and are established cancer risk factors. [...]
2022 - 10.3390/cancers14020353
Cancers, Vol. 14 Núm. 2 (1-2 2022) , p. 353  

Depósito Digital de Documentos de la UAB : Encontrados 38 registros   1 - 10siguientefinal  ir al registro:
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