Dipòsit Digital de Documents de la UAB 14 registres trobats  1 - 10següent  anar al registre: La cerca s'ha fet en 0.01 segons. 
1.
Phytosterol metabolism in plant positive-strand RNA virus replication / Altabella Artigas, Teresa (Centre de Recerca en Agrigenòmica) ; Ramirez-Estrada, Karla (Universidad Autónoma de Nuevo León (Mèxic)) ; Ferrer, Albert (Centre de Recerca en Agrigenòmica)
The genome of most plant viruses consists of a single positive-strand of RNA (+ ssRNA). Successful replication of these viruses is fully dependent on the endomembrane system of the infected cells, which experiences a massive proliferation and a profound reshaping that enables assembly of the macromolecular complexes where virus genome replication occurs. [...]
2021 - 10.1007/s00299-021-02799-x
Plant Cell Reports, (October 2021)  
2.
3 p, 482.6 KB Our Journey Through Advanced Therapies to Reduce Post-Infarct Scarring / Roura, Santiago (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Monguió-Tortajada, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Prat-Vidal, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
2021 - 10.1007/s12015-021-10190-2
Stem Cell Reviews and Reports, Vol. 17 (may 2021) , p. 1928-1930  
3.
15 p, 4.2 MB GATA2 Promotes Hematopoietic Development and Represses Cardiac Differentiation of Human Mesoderm / Castaño Cardoso, Julio (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Aranda, S. (Universitat Pompeu Fabra. Centre de Regulació Genòmica (CRG-UPF)) ; Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Calero-Nieto, F.J. (Department of Hematology. Wellcome and MRC Cambridge Stem Cell Institute and Cambridge Institute for Medical Research. University of Cambridge) ; Mejia-Ramirez, E. (Centro de Medicina Regenerativa de Barcelona) ; Mosquera, J.L. (Institut d'Investigació Biomèdica de Bellvitge) ; Blanco, E. (Universitat Pompeu Fabra. Centre de Regulació Genòmica (CRG-UPF)) ; Wang, X. (Department of Hematology. Wellcome and MRC Cambridge Stem Cell Institute and Cambridge Institute for Medical Research. University of Cambridge) ; Prieto, Cristina (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Zabaleta, L. (Laboratory of Hematological Diseases. Fundación Inbiomed) ; Mereu, E. (Centre de Regulació Genòmica) ; Rovira, M. (Centro de Medicina Regenerativa de Barcelona) ; Jiménez-Delgado, S. (Centro de Medicina Regenerativa de Barcelona) ; Matson, D.R. (Department of Cell and Regenerative Biology. UW-Madison Blood Research Program. Carbone Cancer Center. University of Wisconsin School of Medicine and Public Health) ; Heyn, H. (Universitat Pompeu Fabra) ; Bresnick, E.H. (Department of Cell and Regenerative Biology. UW-Madison Blood Research Program. Carbone Cancer Center. University of Wisconsin School of Medicine and Public Health) ; Göttgens, Berthold (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Di Croce, Luciano (Institució Catalana de Recerca i Estudis Avançats) ; Menéndez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Raya, A. (Institució Catalana de Recerca i Estudis Avançats) ; Giorgetti, A. (Centro de Medicina Regenerativa de Barcelona) ; Universitat Autònoma de Barcelona
In vertebrates, GATA2 is a master regulator of hematopoiesis and is expressed throughout embryo development and in adult life. Although the essential role of GATA2 in mouse hematopoiesis is well established, its involvement during early human hematopoietic development is not clear. [...]
2019 - 10.1016/j.stemcr.2019.07.009
Stem cell reports, Vol. 13 Núm. 3 (october 2019) , p. 515-529  
4.
18 p, 3.6 MB hnRNPDL phase separation is regulated by alternative splicing and disease-causing mutations accelerate its aggregation / Batlle Carreras, Cristina (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Yang, Peiguo (St. Jude Children's Research Hospital (Memphis, Estats Units d'Amèrica)) ; Coughlin, Maura (St. Jude Children's Research Hospital (Memphis, Estats Units d'Amèrica)) ; Messing, James (Howard Hughes Medical Institute) ; Pesarrodona Roches, Mireia (Institut de Recerca Biomèdica de Lleida) ; Szulc, Elzbieta (Institut de Recerca Biomèdica de Lleida) ; Salvatella, Xavier (Institut de Recerca Biomèdica de Lleida) ; Kim, Hong Joo (St. Jude Children's Research Hospital (Memphis, Estats Units d'Amèrica)) ; Taylor, J. Paul (Howard Hughes Medical Institute) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Prion-like proteins form multivalent assemblies and phase separate into membraneless organelles. Heterogeneous ribonucleoprotein D-like (hnRNPDL) is a RNA-processing prion-like protein with three alternative splicing (AS) isoforms, which lack none, one, or both of its two disordered domains. [...]
2020 - 10.1016/j.celrep.2019.12.080
Cell reports, Vol. 30, issue 4 (Jan. 2020) , p. 1117-1128  
5.
20 p, 4.2 MB Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms / Ghosh, Eshan (Indian Institute of Technology, Kanpur) ; Dwivedi, Hemlata (Indian Institute of Technology, Kanpur) ; Baidya, Mithu (Indian Institute of Technology, Kanpur) ; Srivastava, Ashish (Indian Institute of Technology, Kanpur) ; Kumari, Punita (Indian Institute of Technology, Kanpur) ; Stepniewski, Tomek (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Kim, Hee Ryung (Sungkyunkwan University, South Korea) ; Lee, Mi-Hye (Medical University of South Carolina) ; van Gastel, Jana (University of Antwerp) ; Chaturvedi, Madhu (Indian Institute of Technology, Kanpur) ; Roy, Debarati (Indian Institute of Technology, Kanpur) ; Pandey, Shubhi (Indian Institute of Technology, Kanpur) ; Maharana, Jagannath (Indian Institute of Technology, Kanpur) ; Guixà González, Ramon (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Luttrell, Louis M. (Medical University of South Carolina) ; Chung, Ka Young (Sungkyunkwan University, South Korea) ; Dutta, Somnath (Indian Institute of Sciences, Bangalore) ; Selent, Jana (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Shukla, Arun K. (Indian Institute of Technology, Kanpur)
Ghosh et al. discover structural differences between β-arrestin isoforms (β-arrestin 1 and 2), which are universal regulators of signaling and trafficking of G-protein-coupled receptors (GPCRs). These findings have direct implications for understanding the regulatory and signaling paradigms of GPCRs and designing novel therapeutics targeting this important class of receptors.
2019 - 10.1016/j.celrep.2019.08.053
Cell reports, Vol. 28 Núm. 13 (24 2019) , p. 3287-3299.e6  
6.
30 p, 7.5 MB The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer / De Mattos-Arruda, Leticia (Vall d'Hebron Institut d'Oncologia) ; Sammut, S.J. (Department of Oncology and Cancer Research UK Cambridge Institute. Li Ka Shing Centre. University of Cambridge) ; Ross, E.M. (Department of Oncology and Cancer Research UK Cambridge Institute. Li Ka Shing Centre. University of Cambridge) ; Bashford-Rogers, R. (Department of Medicine. University of Cambridge) ; Greenstein, E. (Weizmann Institute of Science (Israel). Department of Immunology) ; Markus, H. (Mayo Clinic Center for Individualized Medicine) ; Morganella, S. (Department of Medical Genetics. The Clinical School. University of Cambridge) ; Teng, Y. (Cancer Molecular Diagnosis Laboratory. NIHR Cambridge Biomedical Research Centre) ; Maruvka, Y. (Massachusetts General Hospital (Boston)) ; Pereira, B. (Department of Oncology and Cancer Research UK Cambridge Institute. Li Ka Shing Centre. University of Cambridge) ; Rueda, O.M. (Department of Oncology and Cancer Research UK Cambridge Institute. Li Ka Shing Centre. University of Cambridge) ; Chin, S.F. (Department of Oncology and Cancer Research UK Cambridge Institute. Li Ka Shing Centre. University of Cambridge) ; Contente-Cuomo, T. (Mayo Clinic Center for Individualized Medicine) ; Mayor, R. (Centro de Investigación Biomédica en Red de Cáncer) ; Arias, Alexandra (Vall d'Hebron Institut d'Oncologia) ; Ali, H.R. (Department of Oncology and Cancer Research UK Cambridge Institute. Li Ka Shing Centre. University of Cambridge) ; Cope, W. (Department of Oncology and Cancer Research UK Cambridge Institute. Li Ka Shing Centre. University of Cambridge) ; Tiezzi, D. (Department of Oncology and Cancer Research UK Cambridge Institute. Li Ka Shing Centre. University of Cambridge) ; Dariush, A. (Institute of Astronomy. University of Cambridge) ; Dias Amarante, T. (Department of Medical Genetics. The Clinical School. University of Cambridge) ; Reshef, D. (Weizmann Institute of Science (Israel). Department of Immunology) ; Ciriaco, 0000-0002-1151-554X (Hospital Universitari Vall d'Hebron) ; Martinez-Saez, Elena (Hospital Universitari Vall d'Hebron) ; Peg, Vicente (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cortés, Javier (Vall d'Hebron Institut d'Oncologia) ; Vassiliou, G. (Wellcome Trust/MRC Cambridge Stem Cell Institute) ; Getz, G. (Massachusetts General Hospital (Boston)) ; Nik-Zainal, S. (Department of Medical Genetics. The Clinical School. University of Cambridge) ; Murtaza, M. (Mayo Clinic Center for Individualized Medicine) ; Friedman, N. (Weizmann Institute of Science (Israel). Department of Immunology) ; Markowetz, F. (Department of Oncology and Cancer Research UK Cambridge Institute. Li Ka Shing Centre. University of Cambridge) ; Seoane Suárez, Joan (Vall d'Hebron Institut d'Oncologia) ; Caldas, C. (Cancer Research UK Cambridge Cancer Centre (Regne Unit)) ; Universitat Autònoma de Barcelona
The detailed molecular characterization of lethal cancers is a prerequisite to understanding resistance to therapy and escape from cancer immunoediting. We performed extensive multi-platform profiling of multi-regional metastases in autopsies from 10 patients with therapy-resistant breast cancer. [...]
2019 - 10.1016/j.celrep.2019.04.098
Cell reports, Vol. 27 Núm. 9 (28 2019) , p. 2690-2708.e10  
7.
26 p, 7.4 MB Three-dimensional genomic structure and cohesin occupancy correlate with transcriptional activity during spermatogenesis / Vara, Covadonga (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Paytuví-Gallart, Andreu (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cuartero, Yasmina (Centre de Regulació Genòmica) ; Le Dily, François (Centre de Regulació Genòmica) ; García, Francisca (Universitat Autònoma de Barcelona. Servei de Cultius Cel·lulars, Producció d'Anticossos i Citometria) ; Salvà Castro, Judith (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gomez Hernández, Laura (Centro de Investigación del Cáncer) ; Julià, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ; Moutinho, Catia (Centre de Regulació Genòmica) ; Aiese Cigliano, Riccardo (Sequentia Biotech) ; Sanseverino, Walter (Sequentia Biotech) ; Fornas, Óscar (Centre de Regulació Genòmica) ; Martín Pendas, Alberto (Centro de Investigación del Cáncer) ; Heyn, Holger (Centre de Regulació Genòmica) ; Waters, Paul D. (University of New South Wales. School of Biotechnology and Biomolecular Sciences) ; Martí Renom, Marc A. (Centre de Regulació Genòmica) ; Ruiz-Herrera Moreno, Aurora (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Mammalian gametogenesis involves dramatic and tightly regulated chromatin remodeling, whose regulatory pathways remain largely unexplored. Here, we generate a comprehensive high-resolution structural and functional atlas of mouse spermatogenesis by combining in situ chromosome conformation capture sequencing (Hi-C), RNA sequencing (RNA-seq), and chromatin immunoprecipitation sequencing (ChIP-seq) of CCCTC-binding factor (CTCF) and meiotic cohesins, coupled with confocal and super-resolution microscopy. [...]
2019 - 10.1016/j.celrep.2019.06.037
Cell reports, Vol. 28, issue 2 (Jul. 2019) , p. 352-367  
8.
14 p, 5.0 MB Single-cell telomere-length quantification couples telomere length to meristem activity and stem cell development in Arabidopsis / González-García, Mary Paz (Centre de Recerca en Agrigenòmica) ; Pavelescu, Irina (Centre de Recerca en Agrigenòmica) ; Canela, Andrés (Centro Nacional de Investigaciones Oncológicas) ; Sevillano, Xavier (Universitat Ramon Llull. Grup de Recerca en Tecnologies Mèdia) ; Leehy, Katherine A. (Texas A&M University. Department of Biochemistry and Biophysics) ; Nelson, Andrew D.L. (Texas A&M University. Department of Biochemistry and Biophysics) ; Ibañes, Marta (Universitat de Barcelona. Departament d'Estructura i Constituents de la Matèria) ; Shippen, Dorothy E. (Texas A&M University. Department of Biochemistry and Biophysics) ; Blasco, María A. (Centro Nacional de Investigaciones Oncológicas) ; Caño Delgado, Ana I. (Centre de Recerca en Agrigenòmica)
Telomeres are specialized nucleoprotein caps that protect chromosome ends assuring cell division. Single-cell telomere quantification in animals established a critical role for telomerase in stem cells, yet, in plants, telomere-length quantification has been reported only at the organ level. [...]
2015 - 10.1016/j.celrep.2015.04.013
Cell reports, Vol. 11, issue 6 (May 2015) , p. 977-989  
9.
12 p, 1.3 MB Genome engineering and plant breeding : impact on trait discovery and development / Nogué, Fabien (INRA Centre de Versailles) ; Mara, Kostlend (INRA Centre de Versailles) ; Collonnier, Cécile (INRA Centre de Versailles) ; Casacuberta i Suñer, Josep M. 1962- (Centre de Recerca en Agrigenòmica)
Key message: New tools for the precise modification of crops genes are now available for the engineering of new ideotypes. A future challenge in this emerging field of genome engineering is to develop efficient methods for allele mining. [...]
2016 - 10.1007/s00299-016-1993-z
Plant cell reports, Vol. 35, Issue 7 (July 2016) , p. 1475-1486  
10.
14 p, 2.3 MB SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation / O'Rourke, Jacqueline Gire (University of California) ; Gareau, Jaclyn R. (Sloan-Kettering Institute) ; Ochaba, Joseph (University of California) ; Song, Wan (University of California) ; Raskó, Tamás (Max-Delbrueck-Center for Molecular Medicine) ; Reverter i Cendrós, David (Sloan-Kettering Institute) ; Lee, John (University of Iowa) ; Mas Monteys, Alexandre (University of Iowa) ; Pallos, Judit (University of California) ; Mee, Lisa (University of California) ; Vashishtha, Malini (University of California) ; Apostol, Barbara L. (University of California) ; Nicholson, Thomas Peter (Enzo Life Sciences Ltd.) ; Illes, Katalin (University of California) ; Zhu, Ya-Zhen (University of California) ; Dasso, Mary (National Institute of Child Health and Development) ; Bates, Gillian P. (King's College London) ; Difiglia, Marian (Harvard Medical School) ; Davidson, Beverly (University of Iowa) ; Wanker, Erich E. (Max-Delbrueck-Center for Molecular Medicine) ; Marsh, J. Lawrence (University of California) ; Lima, Christopher D. (Sloan-Kettering Institute) ; Steffan, Joan S. (University of California) ; Thompson, Leslie M. (University of California.)
A key feature in Huntington disease (HD) is the accumulation of mutant Huntingtin (HTT) protein, which may be regulated by posttranslational modifications. Here, we define the primary sites of SUMOmodification in the amino-terminal domain of HTT, show modification downstream of this domain, and demonstrate that HTT is modified by the stress-inducible SUMO-2. [...]
2013 - 10.1016/j.celrep.2013.06.034
Cell reports, Vol. 4, Issue 2 (July 2013) , p. 362-375  

Dipòsit Digital de Documents de la UAB : 14 registres trobats   1 - 10següent  anar al registre:
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