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1.
12 p, 455.3 KB Challenges in applying the GRADE approach in public health guidelines and systematic reviews : a concept article from the GRADE Public Health Group / Hilton Boon, Michele (MRC/CSO Social and Public Health Sciences Unit, University of Glasgow) ; Thomson, Hilary (MRC/CSO Social and Public Health Sciences Unit, University of Glasgow) ; Shaw, Beth (Center for Evidence-based Policy, Oregon Health & Science University) ; Akl, Elie A. (Department of Internal Medicine, American University of Beirut) ; Lhachimi, Stefan K. (Health Sciences Bremen, University of Bremen) ; Lopez-Alcalde, Jesus (Universitat Autònoma de Barcelona. Departament de Pediatria, d'Obstetrícia i Ginecologia i de Medicina Preventiva) ; Klugar, Miloslav (Faculty of Medicine, Czech National Centre for Evidence-Based Healthcare and Knowledge Translation) ; Choi, Leslie (The Department of Vector Biology, Partnership for Increasing the Impact of Vector Control, Liverpool School of Tropical Medicine) ; Saz-Parkinson, Zuleika (European Commission, Joint Research Centre, Ispra, Italy) ; Mustafa, Reem A. (Departments of Medicine and Biomedical & Health Informatics, University of Missouri-Kansas City) ; Langendam, Miranda W. (Amsterdam Universitair Medische Centra) ; Crane, Olivia (National Institute for Health and Care Excellence (NICE)) ; Morgan, Rebecca L. (Department of Health Research Methods, Evidence, and Impact, McMaster University) ; Rehfuess, Eva (Institute for Medical Informatics, Biometry and Epidemiology, Pettenkofer School of Public Health, LMU Munich) ; Johnston, Bradley C. (Department of Nutrition, Texas A&M University) ; Chong, Lee Yee (Cochrane Public Health and Health Systems Network, University of Oxford) ; Guyatt, Gordon H. (Department of Health Research Methods, Evidence, and Impact, McMaster University, Canada) ; Schünemann, Holger J. (Department of Health Research Methods, Michael G DeGroote Cochrane Canada and McMaster GRADE Centres, and WHO Collaborating Centre for Infectious Diseases, Research Methods and Recommendations, Evidence, and Impact, McMaster University) ; Katikireddi, Srinivasa Vittal (MRC/CSO Social and Public Health Sciences Unit, University of Glasgow)
This article explores the need for conceptual advances and practical guidance in the application of the GRADE approach within public health contexts. We convened an expert workshop and conducted a scoping review to identify challenges experienced by GRADE users in public health contexts. [...]
2021 - 10.1016/j.jclinepi.2021.01.001
Journal of Clinical Epidemiology, Vol. 135 (july 2021) , p. 42-53  
2.
8 p, 535.7 KB The impact of rheumatoid arthritis on the risk of adverse events following joint replacement : a real-world cohort study / Burn, Edward (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK) ; Edwards, Christopher J (NIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton, Southampton, UK) ; Murray, David W (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK) ; Silman, Alan (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK) ; Cooper, Cyrus (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ; Arden, Nigel K (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ; Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Pinedo-Villanueva, Rafael (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ; Universitat Autònoma de Barcelona
To assess whether rheumatoid arthritis (RA) is associated with a greater risk of adverse events following total knee replacement (TKR) and total hip replacement (THR) than osteoarthritis (OA). Individuals with a diagnosis of RA or OA were identified using primary care records. [...]
2018 - 10.2147/CLEP.S160347
Clinical Epidemiology, Vol. 10 (june 2018) , p. 697-704  
3.
15 p, 1.4 MB Comparative anti-fracture effectiveness of different oral anti-osteoporosis therapies based on "real-world" data : a meta-analysis of propensity-matched cohort findings from the UK Clinical Practice Research Database and the Catalan SIDIAP Database / Khalid, Sara (Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom) ; Calderon-Larrañaga, Sara (Family and Community Medicine Teaching Unit of Granada. Cartuja University Health Centre. Andalusian Health Service (SAS), Granada, Spain) ; Hawley, Samuel (Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom) ; Ali, M Sanni (London School of Hygiene and Tropical Medicine, London, United Kingdom) ; Judge, Andrew (Bristol NIHR Biomedical Research Centre (Bristol, Regne Unit)) ; Arden, Nigel (University of Oxford. Arthritis Research UK Centre for Sport, Exercise, and Osteoarthritis) ; van Staa, Tjeerd (Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands) ; Cooper, Cyrus (NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom) ; Javaid, Muhammad Kassim (Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom) ; Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Universitat Autònoma de Barcelona
This paper aims to compare the clinical effectiveness of oral anti-osteoporosis drugs based on the observed risk of fracture while on treatment in primary care actual practice. We investigated two primary care records databases covering UK National Health Service (Clinical Practice Research Datalink, CPRD) and Catalan healthcare (Information System for Research in Primary Care, SIDIAP) patients during 1995-2014 and 2006-2014, respectivey. [...]
2018 - 10.2147/CLEP.S164112
Clinical Epidemiology, Vol. 10 (october 2018) , p. 1417-1431  
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9 p, 883.8 KB Hepatitis C infection substantially reduces survival of alcohol-dependent patients / Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sanvisens, Arantza (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Jarrin, Inmaculada (Instituto de Salud Carlos III) ; Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bolao, Ferran (Hospital Universitari de Bellvitge) ; Tor, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Muñoz, Alvaro (Johns Hopkins University) ; Universitat Autònoma de Barcelona
Heavy alcohol use is associated with life-threatening complications including progressive liver disease. We aimed to analyze the impact of hepatitis C virus (HCV) infection on survival and liver-related death in alcohol-dependent patients. [...]
2018 - 10.2147/CLEP.S162308
Clinical Epidemiology, Vol. 10 (august 2018) , p. 897-905  
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12 p, 786.8 KB Epidemiology of dementia : prevalence and incidence estimates using validated electronic health records from primary care / Ponjoan Thäns, Anna (Institut Català de la Salut. Direcció d'Atenció Primària (Girona, Catalunya)) ; Garre-Olmo, Josep (Institut d'Investigació Biomèdica (Girona)) ; Blanch, Jordi (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Fages, Ester (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Alves-Cabratosa, Lia (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Martí-Lluch, Ruth (Institut Català de la Salut. Direcció d'Atenció Primària (Girona, Catalunya)) ; Comas-Cufí, Marc (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Parramon, Dídac (Universitat Autònoma de Barcelona) ; García-Gil, Maria (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Ramos, Rafel (Universitat de Girona. Departament de Ciències Mèdiques)
Updated estimates of incidence and prevalence of dementia are crucial to ensure adequate public health policy. However, most of the epidemiological studies in the population in Spain were conducted before 2010. [...]
2019 - 10.2147/CLEP.S186590
Clinical Epidemiology, Vol. 11 (march 2019) , p. 217-228  
6.
9 p, 441.3 KB Sample size and power considerations for ordinary least squares interrupted time series analysis : a simulation study / Hawley, Samuel (University of Oxford. Centre for Statistics in Medicine) ; Ali, M Sanni (Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine) ; Berencsi, Klara (Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford) ; Judge, Andrew (Department of Translational Health Sciences, University of Bristol, Bristol, UK) ; Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona)
Interrupted time series (ITS) analysis is being increasingly used in epidemiology. Despite its growing popularity, there is a scarcity of guidance on power and sample size considerations within the ITS framework. [...]
2019 - 10.2147/CLEP.S176723
Clinical Epidemiology, Vol. 11 (2019) , p. 197-205  
7.
18 p, 1.4 MB Survival, effect measures, and impact numbers after dementia diagnosis : a matched cohort study / Garre-Olmo, Josep (Universitat de Girona. Departament de Medicina) ; Ponjoan Thäns, Anna (Universitat Autònoma de Barcelona) ; Inoriza, José Maria (Hospital Universitario de Palamós) ; Blanch, Jordi (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Sánchez-Pérez, Inma (Research Group on Health Services and Health Outcomes (GRESSIRES). Integrated Health Services Baix Empordà (SSIBE)) ; Cubí, Rafel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; de Eugenio, Rosa (Hospital Universitario de Palamós) ; Turró-Garriga, Oriol (Registry of Dementia of Girona. Health Assistance Institute) ; Vilalta-Franch, Joan (Institut d'Investigació Biomèdica (Girona))
Background: Knowledge on survival after diagnosis is important for all stakeholders. We aimed to estimate the survival and life expectancy after a dementia diagnosis, and to quantify the impact of dementia subtypes on mortality. [...]
2019 - 10.2147/CLEP.S213228
Clinical Epidemiology, Vol. 11 (2019) , p. 525-542  
8.
10 p, 2.0 MB Validation of cancer diagnoses in electronic health records : Results from the information system for research in primary care (SIDIAP) in northeast spain / Recalde, Martina (Universitat Autònoma de Barcelona) ; Manzano-Salgado, Cyntia B. (Universitat Autònoma de Barcelona) ; Díaz, Yesika (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Puente, Diana (Universitat Autònoma de Barcelona) ; Garcia-Gil, Maria del Mar (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Marcos-Gragera, Rafael (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Ribes-Puig, Josefa (Universitat de Barcelona. Departament de Ciències Clíniques) ; Galceran, Jaume (Registre de Càncer de Tarragona. Fundació per a la Investigació i Prevenció del Càncer (FUNCA). IISPV) ; Posso, Margarita (Hospital del Mar (Barcelona, Catalunya)) ; Macià, Francesc 1859-1933 (Hospital del Mar (Barcelona, Catalunya)) ; Duarte-Salles, Talita (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Background: Electronic health records are becoming an increasingly valuable resource for epidemiology but their data quality needs to be quantified. We aimed to validate twenty-five types of incident cancer cases in the Information System for Research in Primary Care (SIDIAP) in Catalonia with the population-based cancer registries of Girona and Tarragona as the gold-standard. [...]
2019 - 10.2147/CLEP.S225568
Clinical Epidemiology, Vol. 11 (2019) , p. 1015-1024  
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10 p, 908.1 KB How well can electronic health records from primary care identify Alzheimer's disease cases? / Ponjoan Thäns, Anna (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Garre-Olmo, Josep (Institut d'Investigació Biomèdica (Girona)) ; Blanch, Jordi (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Fages, Ester (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Alves-Cabratosa, Lia (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Martí-Lluch, Ruth (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Comas-Cufí, Marc (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Parramon, Dídac (Institut Català de la Salut) ; García-Gil, Maria (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Ramos, Rafel (Universitat de Girona. Departament de Medicina)
Background: Electronic health records (EHR) from primary care are emerging in Alzheimer's disease (AD) research, but their accuracy is a concern. We aimed to validate AD diagnoses from primary care using additional information provided by general practitioners (GPs), and a register of dementias. [...]
2019 - 10.2147/CLEP.S206770
Clinical Epidemiology, Vol. 11 (2019) , p. 509-518  
10.
12 p, 1.8 MB Validity of a method for the self-screening of cardiovascular risk / Barroso, María (Universitat Autònoma de Barcelona. Departament de Pediatria, d'Obstetrícia i Ginecologia i de Medicina Preventiva) ; Pérez-Fernández, Silvia (Consortium for Biomedical Research in Cardiovascular Disease (CIBERCV)) ; Vila, M Mar (Universitat de Barcelona. Departament de Matemàtiques i Informàtica) ; Zomeño, M Dolors (Universitat Ramon Llull. Departament de Ciències de la Salut) ; Martí-Lluch, Ruth (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Cordon, Ferran (Institut Català de la Salut. Centre d'Atenció Primària Montilivi) ; Ramos, Rafel (Institut d'Investigació Biomèdica (Girona)) ; Elosua, Roberto (Consortium for Biomedical Research in Cardiovascular Disease (CIBERCV)) ; Degano, Irene R (Consortium for Biomedical Research in Cardiovascular Disease (CIBERCV)) ; Fitó, Montse (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ; Cabezas Peña, Carmen (Agència de Salut Pública de Catalunya) ; Salvador, Gemma (Agència de Salut Pública de Catalunya) ; Castell, Conxa (Agència de Salut Pública de Catalunya) ; Grau, María (Universitat de Barcelona. Departament de Medicina)
The validity of a cardiovascular risk self-screening method was assessed. The results obtained for self-measurement of blood pressure, a point-of-care system's assessment of lipid profile and glycated hemoglobin, and a self-administered questionnaire (sex, age, diabetes, tobacco consumption) were compared with the standard screening (gold standard) conducted by a health professional. [...]
2018 - 10.2147/CLEP.S158358
Clinical Epidemiology, Vol. 10 (may 2018) , p. 549-560  

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