Depósito Digital de Documentos de la UAB Encontrados 2 registros  La búsqueda tardó 0.00 segundos. 
1.
4 p, 393.4 KB Copper(II) and the pathological H50Q α-synuclein mutant : environment meets genetics / Villar-Piqué, Anna (University Medical Centre Göottingen. Department of Neurodegeneration and Restorative Research) ; Rossetti, Giulia (Jülich Forschungszentrum. Institut für Neurowissenschaften und Medizin) ; Ventura i Zamora, Salvador (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Carloni, Paolo (Jülich Forschungszentrum. Institut für Neurowissenschaften und Medizin) ; Fernández, Claudio O. (Max Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario) ; Outeiro, Tiago Fleming (University Medical Centre Göottingen. Department of Neurodegeneration and Restorative Research) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Copper is one of the metals described to bind the Parkinson disease-related protein α-synuclein (aSyn), and to promote its aggregation. Although histidine at position 50 in the aSyn sequence is one of the most studied copper-anchoring sites, its precise role in copper binding and aSyn aggregation is still unclear. [...]
2017 - 10.1080/19420889.2016.1270484
Communicative & integrative Biology, Vol. 10, no. 1 (2017) , e127048  
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6 p, 224.0 KB Glutamate receptor mutations in psychiatric and neurodevelopmental disorders / Soto, David (Institut d'Investigació Biomèdica de Bellvitge (IDIBELL). Laboratori de Neurobiologia) ; Altafaj, Xavier (Institut d'Investigació Biomèdica de Bellvitge (IDIBELL). Institut de Neuropatologia) ; Sindreu, Carlos (Universitat de Barcelona. Departament de Farmacologia) ; Bayés, Àlex (Institut d'Investigació Biomèdica Sant Pau (IIB Sant Pau)) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Alterations in glutamatergic neurotransmission have long been associated with psychiatric and neurodevelopmental disorders (PNDD), but only recent advances in high-throughput DNA sequencing have allowed interrogation of the prevalence of mutations in glutamate receptors (GluR) among afflicted individuals. [...]
2014 - 10.4161/cib.27887
Communicative & Integrative Biology, Vol. 7, Issue 1 (January 2014) , e27887  

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