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1.
Outcome of hospitalization for COVID-19 in patients with interstitial lung disease an international multicenter study / Drake, T.M. (Centre for Medical Informatics. The Usher Institute. University of Edinburgh) ; Docherty, A.B. (Centre for Medical Informatics. The Usher Institute. University of Edinburgh) ; Harrison, E.M. (Centre for Medical Informatics. The Usher Institute. University of Edinburgh) ; Quint, J.K. (National Heart and Lung Institute. Imperial College) ; Adamali, H. (Academic Respiratory Unit. University of Bristol. Southmead Hospital) ; Agnew, Sarah (Liverpool Interstitial Lung Disease Service. Aintree site. Liverpool University Hospitals NHS Foundation Trust) ; Babu, S. (Queen Alexandra Hospital) ; Barber, C.M. (Northern General Hospital) ; Barratt, S. (Academic Respiratory Unit. University of Bristol. Southmead Hospital) ; Bendstrup, E. (Centre for Rare Lung Diseases. Department of Respiratory Diseases and Allergy. Aarhus University Hospital) ; Bianchi, S. (Northern General Hospital) ; Castillo Villegas, Diego (Institut d'Investigació Biomèdica Sant Pau) ; Chaudhuri, N. (University of Manchester) ; Chua, F. (Royal Brompton and Harefield NHS Foundation Trust) ; Coker, R. (Respiratory Medicine. Hammersmith Hospital. Imperial College Healthcare NHS Trust) ; Chang, W. (Nottingham University Hospitals NHS Trust) ; Crawshaw, A. (Birmingham Interstitial Lung Disease Unit. Queen Elizabeth Hospital Birmingham. University Hospitals Birmingham NHS Foundation Trust) ; Crowley, L.E. (University of Birmingham) ; Dosanjh, D. (Birmingham Interstitial Lung Disease Unit. Queen Elizabeth Hospital Birmingham. University Hospitals Birmingham NHS Foundation Trust) ; Fiddler, C.A. (Cambridge Interstitial Lung Disease Service. Royal Papworth Hospital NHS Foundation Trust) ; Forrest, I.A. (Department of Respiratory Medicine. Royal Victoria Infirmary. Newcastle upon Tyne Hospitals NHS Foundation Trust) ; George, P.M. (Royal Brompton and Harefield NHS Foundation Trust) ; Gibbons, M.A. (South West Peninsula ILD Network. Royal Devon & Exeter Foundation NHS Trust) ; Groom, K. (Respiratory Medicine. Hammersmith Hospital. Imperial College Healthcare NHS Trust) ; Haney, S. (Northumbria Specialist Emergency Care Hospital. Northumbria Healthcare NHS Foundation Trust) ; Hart, S.P. (Respiratory Research Group. Hull York Medical School. Castle Hill Hospital) ; Heiden, E. (University Hospitals Southampton NHS Foundation Trust) ; Henry, M. (Cork University Hospital) ; Ho, L.P. (Oxford Interstitial Lung Disease Service. Oxford University Hospitals NHS Foundation Trust) ; Hoyles, R.K. (Oxford Interstitial Lung Disease Service. Oxford University Hospitals NHS Foundation Trust) ; Hutchinson, J. (King's Mill Hospital) ; Hurley, K. (Beaumont Hospital) ; Jones, M. (National Institute for Health Research (NIHR). Southampton Biomedical Research Centre & Clinical and Experimental Sciences. University of Southampton) ; Jones, S. (Action for Pulmonary Fibrosis. Stuart House) ; Kokosi, M. (Guys and St. Thomas' NHS Trust) ; Kreuter, M. (Center for Interstitial and Rare Lung Diseases. Pneumology. Thoraxklinik. University of Heidelberg. German Center for Lung Research) ; MacKay, L.S. (Northumbria Specialist Emergency Care Hospital. Northumbria Healthcare NHS Foundation Trust) ; Mahendran, S. (Kingston Hospital NHS Foundation Trust) ; Margaritopoulos, G. (ILD Unit. Manchester University Hospital NHS Foundation Trust. Wythenshawe Hospital) ; Molina Molina, Maria (Institut d'Investigació Biomèdica de Bellvitge) ; Molyneaux, P.L. (National Heart and Lung Institute. Imperial College) ; O'Brien, A. (University Hospital Limerick) ; O'Reilly, K. (Department of Respiratory Medicine. Mater Misericordiae University Hospital) ; Packham, A. (Birmingham Interstitial Lung Disease Unit. Queen Elizabeth Hospital Birmingham. University Hospitals Birmingham NHS Foundation Trust) ; Parfrey, H. (Cambridge Interstitial Lung Disease Service. Royal Papworth Hospital NHS Foundation Trust) ; Poletti, V. (Department of Diseases of the Thorax. Morgagni Hospital) ; Porter, J.C. (UCL Respiratory. University College London. ILD Service. University College London Hospitals NHS Foundation Trust) ; Renzoni, E. (Royal Brompton and Harefield NHS Foundation Trust) ; Rivera-Ortega, P. (ILD Unit. Manchester University Hospital NHS Foundation Trust. Wythenshawe Hospital) ; Russell, A.M. (Imperial Healthcare NHS Trust. St. Mary's Hospital. The Bays) ; Saini, G. (Nottingham University Hospitals NHS Trust) ; Spencer, L.G. (Liverpool Interstitial Lung Disease Service. Aintree site. Liverpool University Hospitals NHS Foundation Trust) ; Stella, G.M. (Laboratory of Biochemistry and Genetics. Pneumology Unit. Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo) ; Stone, H. (University Hospital North Midlands NHS Trust. Royal Stoke University Hospital) ; Sturney, S. (Royal United Hospitals Bath NHS Foundation Trust) ; Thickett, D. (University of Birmingham) ; Thillai, M. (Cambridge Interstitial Lung Disease Service. Royal Papworth Hospital NHS Foundation Trust) ; Wallis, T. (National Institute for Health Research (NIHR). Southampton Biomedical Research Centre & Clinical and Experimental Sciences. University of Southampton) ; Ward, K. (National Heart and Lung Institute. Imperial College) ; Wells, A.U. (Royal Brompton and Harefield NHS Foundation Trust) ; West, A. (Guys and St. Thomas' NHS Trust) ; Wickremasinghe, M. (Imperial Healthcare NHS Trust. St. Mary's Hospital. The Bays) ; Woodhead, F. (Institute of Lung Health. Interstitial Lung Disease Unit. Glenfield Hospital) ; Hearson, G. (NIHR Biomedical Research Centre. Respiratory Research Unit. University of Nottingham) ; Howard, L. (NIHR Biomedical Research Centre. Respiratory Research Unit. University of Nottingham) ; Baillie, J.K. (Intensive Care Unit. Royal Infirmary Edinburgh) ; Openshaw, P.J.M. (National Heart and Lung Institute. Imperial College) ; Semple, M.G. (Respiratory Medicine. Alder Hey Children's Hospital) ; Stewart, I. (NIHR Biomedical Research Centre. Respiratory Research Unit. University of Nottingham) ; Jenkins, R.G. (NIHR Biomedical Research Centre. Respiratory Research Unit. University of Nottingham) ; Universitat Autònoma de Barcelona
Rationale: The impact of coronavirus disease (COVID-19) on patients with interstitial lung disease (ILD) has not been established. Objectives: To assess outcomes in patients with ILD hospitalized for COVID-19 versus those without ILD in a contemporaneous age-, sex-, and comorbidity-matched population. [...]
2020 - 10.1164/rccm.202007-2794OC
American Journal of Respiratory and Critical Care Medicine, Vol. 202 Núm. 12 (15 2020) , p. 1656-1665  
2.
2 p, 223.8 KB Adrenomedullin in COVID-19 induced endotheliitis / Cameron Wilson, Darius (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Schefold, J.C. (Department of Intensive Care Medicine. Inselspital. Bern University Hospital. University of Bern) ; Baldirà, Jaume (Institut d'Investigació Biomèdica Sant Pau) ; Spinetti, Thibaud (Department of Intensive Care Medicine. Inselspital. Bern University Hospital. University of Bern) ; Saeed, Kordo (University Hospital Southampton NHS Foundation Trust) ; Elke, Gunnar (Department of Anaesthesiology and Intensive Care Medicine. University Medical Center Schleswig-Holstein. Campus Kiel) ; Universitat Autònoma de Barcelona
2020 - 10.1186/s13054-020-03151-7
Critical Care, Vol. 24 Núm. 1 (september 2020) , p. 411  
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9 p, 1.0 MB Use of Biomarkers to Identify Acute Kidney Injury to Help Detect Sepsis in Patients With Infection / Kellum, John A. (Department of Critical Care Medicine, Center for Critical Care Nephrology, University of Pittsburgh School of Medicine, Pittsburgh, PA) ; Artigas, Antonio (Parc Taulí Hospital Universitari) ; Gunnerson, Kyle J. (Departments of Emergency Medicine/Critical Care, Anesthesiology, Internal Medicine, Michigan Center for Integrative Research in Critical Care (MCIRCC), University of Michigan, Ann Arbor, MI) ; Honore, Patrick M. (Department of Intensive Care Medicine, Brugmann University Hospital, Brussels, Belgium) ; Kampf, J. Patrick (Astute Medical, Inc. (a bioMérieux company), San Diego, CA) ; Kwan, Thomas (Astute Medical, Inc. (a bioMérieux company), San Diego, CA) ; McPherson, Paul (Astute Medical, Inc. (a bioMérieux company), San Diego, CA) ; Nguyen, H. Bryant (Division of Pulmonary and Critical Care Medicine, Department of Medicine, Loma Linda University, Loma Linda, CA) ; Rimmelé, Thomas (Department of Anesthesiology and Critical Care Medicine, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France) ; Shapiro, Nathan I. (Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA) ; Shi, Jing (Walker BioSciences, Carlsbad, CA) ; Vincent, Jean-Louis (Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium) ; Chawla, Lakhmir S. (Department of Medicine, Veterans Affairs Medical Center, San Diego, CA) ; Universitat Autònoma de Barcelona
Supplemental Digital Content is available in the text. Retrospective, international, Sapphire study. Academic Medical Center. Adults admitted to the ICU without evidence of acute kidney injury at time of enrollment. [...]
2021 - 10.1097/CCM.0000000000004845
Critical Care Medicine, Vol. 49 (january 2021) , p. e360-e368  
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10 p, 642.7 KB Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients With Sepsis / Honore, Patrick M. (Vrije Universiteit Amsterdam) ; Nguyen, H. Bryant (Department of Medicine, Pulmonary and Critical Care Medicine and Department of Emergency Medicine, Loma Linda University, Loma Linda, CA) ; Gong, Michelle (Division of Critical Care Medicine, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY) ; Chawla, Lakhmir S. (Department of Medicine, Division of Intensive Care Medicine and Division of Nephrology, Veterans Affairs Medical Center, and Department of Anesthesiology and Critical Care Medicine, George Washington University Medical Center, Washington, DC) ; Bagshaw, Sean M. (Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada) ; Artigas, Antonio (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Shi, Jing (Walker Biosciences, Carlsbad, CA) ; Joannes-Boyau, Olivier (Department of Anesthesiology and Critical Care Medicine 2, Hospital Haut Leveque, University of Bordeaux 2, Bordeaux, France) ; Vincent, Jean-Louis (Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium) ; Kellum, John A. ; Universitat Autònoma de Barcelona
Supplemental Digital Content is available in the text. To examine the performance of the urinary biomarker panel tissue inhibitor of metalloproteinase-2 and insulin-like growth factor-binding protein 7 in patients with sepsis at ICU admission. [...]
2016 - 10.1097/CCM.0000000000001827
Critical Care Medicine, Vol. 44 (september 2016) , p. 1851-1860  
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10 p, 1.2 MB Influenza and associated co-infections in critically ill immunosuppressed patients / Martin-Loeches, Ignacio (St. James's Hospital. Department of Intensive Care Medicine) ; Lemiale, Virginie (Hôpital Saint-Louis and Paris Diderot Sorbonne University. Medical Intensive Care Unit) ; Geoghegan, Pierce (Trinity College. Department of Clinical Medicine, Wellcome Trust-HRB Clinical Research Facility, St. James Hospital) ; McMahon, Mary Aisling (Trinity College. Department of Clinical Medicine, Wellcome Trust-HRB Clinical Research Facility, St. James Hospital) ; Pickkers, Peter (Radboud University Medical Centre. Department of Intensive Care Medicine (710)) ; Soares, Marcio (D'Or Institute for Research and Education (Rio de Janeiro, Brasil)) ; Perner, Anders (University of Copenhagen) ; Meyhoff, Tine Sylvest (University of Copenhagen) ; Bukan, Ramin Brandt (Herlev University Hospital. Department of Anesthesiology I) ; Rello, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bauer, Philippe R. (Mayo Clinic. Pulmonary and Critical Care Medicine) ; van de Louw, Andry (Penn State University College of Medicine. Division of Pulmonary and Critical Care) ; Taccone, Fabio Silvio (Université Libre de Bruxelles (ULB). Department of Intensive Care, Hôpital Erasme) ; Salluh, Jorge (D'Or Institute for Research and Education (Rio de Janeiro, Brasil)) ; Hemelaar, Pleun (Radboud University Medical Centre. Department of Intensive Care Medicine (710)) ; Schellongowski, Peter (Medical University of Vienna. Department of Medicine I) ; Rusinova, Katerina (Charles University in Prague and General University Hospital. Department of Anesthesiology and Intensive Care Medicine and Institute for Medical Humanities, 1st Faculty of Medicine) ; Terzi, Nicolas (Université Grenoble-Alpes. CHU Grenoble Alpes, Service de Réanimation Médicale, Faculté de Médecine de Grenoble, INSERM U1042) ; Mehta, Sangeeta (University of Toronto. Department of Medicine) ; Antonelli, Massimo (Università Cattolica del Sacro Cuore. Agostino Gemelli University Hospital) ; Kouatchet, Achille (University Hospital of Angers. Department of Medical Intensive Care Medicine) ; Klepstad, Pål (Norwegian University of Science and Technology) ; Valkonen, Miia (University of Helsinki. Division of Intensive Care Medicine, Department of Anesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital) ; Landburg, Precious Pearl (University Medical Center Groningen. Department of Critical Care) ; Barratt-Due, Andreas (University of Oslo. Department of Immunology-Department of Emergencies and Critical Care) ; Bruneel, Fabrice (Centre Hospitalier de Versailles. Medical-Surgical Intensive Care Unit) ; Pène, Frédéric (Medical ICU, Cochin Hospital, Assistance Publique-Hôpitaux de Paris and University Paris Descartes) ; Metaxa, Victoria (King's College Hospital NHS Foundation Trust) ; Moreau, Anne Sophie (University of Lille. Critical Care Center, CHU Lille, School of Medicine) ; Souppart, Virginie (Hôpital Saint-Louis and Paris Diderot Sorbonne University. Medical Intensive Care Unit) ; Burghi, Gaston (Hospital Maciel. Terapia Intensiva) ; Girault, Christophe (Normandie Univ, UNIROUEN, EA-3830, Rouen University Hospital. Department of Medical Intensive Care) ; Silva, Ulysses V. A. (ICU, Fundação Pio XII - Barretos Cancer Hospital) ; Montini, Luca (Università Cattolica del Sacro Cuore. Agostino Gemelli University Hospital) ; Barbier, Francois (La Source Hospital - CHR Orléans. Medical Intensive Care Unit) ; Nielsen, Lene B. (Odense University Hospital. Department of Anaesthesia and Intensive Care) ; Gaborit, Benjamin (Hôtel Dieu-HME-University Hospital of Nantes. Medical Intensive Care Unit) ; Mokart, Djamel (Institut Paoli-Calmettes. Réanimation Polyvalente et Département d'Anesthésie et de Réanimation) ; Chevret, Sylvie (ECSTRA Team, Biostatistics and Clinical Epidemiology, UMR 1153, INSERM, Paris Diderot Sorbonne University and Service de Biostatistique et Information Médicale AP-HP, Hôpital Saint-Louis) ; Azoulay, Elie (Hôpital Saint-Louis and Paris Diderot Sorbonne University. Medical Intensive Care Unit) ; Universitat Autònoma de Barcelona
It is unclear whether influenza infection and associated co-infection are associated with patient-important outcomes in critically ill immunocompromised patients with acute respiratory failure. Preplanned secondary analysis of EFRAIM, a prospective cohort study of 68 hospitals in 16 countries. [...]
2019 - 10.1186/s13054-019-2425-6
Critical Care, Vol. 23 (may 2019)  
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2 p, 421.0 KB Low molecular weight heparins in COVID-19 patients : beware of augmented renal clearance! / Tomasa-Irriguible, Teresa Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez-Vega, Sergi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mor-Marco, Ester (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Herraiz-Ruiz, Alba (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Raguer-Pardo, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cubells Larrosa, Carles (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
2020 - 10.1186/s13054-020-03058-3
Critical Care, Vol. 24 Núm. 1 (october 2020) , p. 325  
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Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation : An observational study in a large dataset from critically ill patients / de Haro, Candelaria (Universitat Autònoma de Barcelona. Departament de Medicina) ; Magrans, Rudys (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; López-Aguilar, Josefina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Montanyà, Jaume (Better Care) ; Lena, Enrico (Department of Perioperative Medicine. Intensive Care and Emergency. Cattinara Hospital. Trieste University) ; Subirà, Carles (Fundació Althaia (Manresa, Catalunya)) ; Fernandez-Gonzalo, Sol (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Gomà, Gemma. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Fernández, Rafael (Fundació Althaia (Manresa, Catalunya)) ; Albaiceta, Guillermo M. (Universidad de Oviedo. Departamento de Biología Funcional) ; Skrobik, Yoanna (McGill University. Department of Medicine) ; Lucangelo, Umberto (Department of Perioperative Medicine. Intensive Care and Emergency. Cattinara Hospital. Trieste University) ; Murias, Gastón (Critical Care Department. Hospital Británico) ; Ochagavia, Ana (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Kacmarek, Robert M. (Harvard Medical School) ; Rue, Montserrat (Universitat de Lleida. Departament de Ciències Mèdiques Bàsiques) ; Blanch, Lluís (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Background: In critically ill patients, poor patient-ventilator interaction may worsen outcomes. Although sedatives are often administered to improve comfort and facilitate ventilation, they can be deleterious. [...]
2019 - 10.1186/s13054-019-2531-5
Critical Care, Vol. 23 Núm. 1 (may 2019) , p. 245  
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9 p, 1.2 MB Population pharmacokinetics/pharmacodynamics of micafungin against Candida species in obese, critically ill, and morbidly obese critically ill patients / Maseda, Emilio (Madrid, Spain) ; Grau, Santiago (Institut Hospital del Mar d'Investigacions Mèdiques) ; Luque, Sonia (Hospital del Mar (Barcelona, Catalunya)) ; Castillo-Mafla, Maria-Pilar (Paseo de la Castellana 261, 28046 Madrid, Spain) ; Suárez-de-la-Rica, Alejandro (Paseo de la Castellana 261, 28046 Madrid, Spain) ; Montero-Feijoo, Ana (Paseo de la Castellana 261, 28046 Madrid, Spain) ; Salgado, Patricia (Paseo de la Castellana 261, 28046 Madrid, Spain) ; Gimenez, Maria-Jose (PRISM-AG, Madrid, Spain) ; García-Bernedo, Carlos A. (Hospital del Mar (Barcelona, Catalunya)) ; Gilsanz, Fernando (Madrid, Spain) ; Roberts, Jason A. (Brisbane, Australia) ; Universitat Autònoma de Barcelona
Dosing in obese critically ill patients is challenging due to pathophysiological changes derived from obesity and/or critical illness, and it remains fully unexplored. This study estimated the micafungin probability of reaching adequate 24-h area under the curve (AUC)/minimum inhibitory concentration (MIC) values against Candida spp. [...]
2018 - 10.1186/s13054-018-2019-8
Critical Care, Vol. 22 (april 2018)  
9.
8 p, 202.9 KB Prevention of Ventilator-Associated Pneumonia : The Multimodal Approach of the Spanish ICU "Pneumonia Zero" Program* / Álvarez-Lerma, Francisco (Institut Hospital del Mar d'Investigacions Mèdiques) ; Palomar-Martínez, Mercedes ; Sánchez-García, Miguel (Hospital Clínico San Carlos (Madrid)) ; Martínez-Alonso, Montserrat ; Álvarez-Rodríguez, Joaquín (Service of Intensive Care Medicine, SEMICYUC Working Group on Safety, Quality and Management, Hospital de Fuenlabrada, Fuenlabrada, Madrid, Spain) ; Lorente, Leonardo (Service of Intensive Care Medicine, SEMICYUC Working Group on Infectious Diseases, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain) ; Arias-Rivera, Susana (Hospital Universitario de Getafe (Madrid)) ; García, Rosa (Hospital de Basurto (Bilbao, Biscaia)) ; Gordo, Federico (Service of Intensive Care Medicine, SEMICYUC Working Group on Acute Respiratory Insufficiency, Hospital Universitario del Henares, Colsada, Madrid, Spain) ; Añón, José M. (Instituto de Investigación Hospital Universitario La Paz) ; Jam-Gatell, Rosa (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Vázquez-Calatayud, Mónica (Clínica Universidad de Navarra) ; Agra Varela, Yolanda (Patient Safety Unit, Spanish Ministry of Health, Social Policy and Equality, Madrid, Spain) ; Universitat Autònoma de Barcelona
Supplemental Digital Content is available in the text. The "Pneumonia Zero" project is a nationwide multimodal intervention based on the simultaneous implementation of a comprehensive evidence-based bundle measures to prevent ventilator-associated pneumonia in critically ill patients admitted to the ICU. [...]
2018 - 10.1097/CCM.0000000000002736
Critical Care Medicine, Vol. 46 (january 2018) , p. 181-188  
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13 p, 786.1 KB A randomized placebo-controlled phase II study of a Pseudomonas vaccine in ventilated ICU patients / Rello, Jordi (Hospital Universitari Vall d'Hebron) ; Krenn, Claus-Georg (Medical University of Vienna) ; Locker, Gottfried (Medical University of Vienna) ; Pilger, Ernst (University Hospital Graz, Graz, Austria) ; Madl, Christian (Medical University of Vienna) ; Balica, Laura (Emergency Clinical Hospital Bucharest) ; Dugernier, Thierry (Clinique St. Pierre, Ottignies, Belgium) ; Laterre, Pierre-Francois (St. Luc University Hospital UCL, Université Catholique de Louvain, Brussels, Belgium) ; Spapen, Herbert (University Hospital Vrije Universiteit Brussels, Brussels, Belgium) ; Depuydt, Pieter (UZ Gent, Gent, Belgium) ; Vincent, Jean-Louis (Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium) ; Bogár, Lajos (University of Pécs, Pécs, Hungary) ; Szabó, Zsuzsanna (Uzsoki Hospital, Budapest, Hungary) ; Völgyes, Barbara (Bajcsy Zsilinszky Hospital and Polyclinic, Budapest, Hungary) ; Máñez, Rafael (Hospital Universitari de Bellvitge) ; Cakar, Nahit (Istanbul University Capa Medical Faculty, Istanbul, Turkey) ; Ramazanoglu, Atilla (Akdeniz University, Antalya, Turkey) ; Topeli, Arzu (Hacettepe University Hospital, Ankara, Turkey) ; Mastruzzo, Maria A. (Hospital Dr. Carlos Bocalandro, Buenos Aires, Argentina) ; Jasovich, Abel (Sanatorio Güemes, Buenos Aires, Argentina) ; Remolif, Christian G. (Hospital "Heroes de Malvinas", Buenos Aires, Argentina) ; del Carmen Soria, Liliana (Hospital Central Mendoza, Ciudad de Mendoza, Argentina) ; Andresen Hernandez, Max A. (Pontificia Universidad Católica de Chile) ; Ruiz Balart, Carolina (Hospital Dr. Sótero del Rio, Santiago, Chile) ; Krémer, Ildikó (Flor Ferenc County Hospital, Kistarcsa, Hungary) ; Molnár, Zsolt (University of Szeged, Szeged, Hungary) ; von Sonnenburg, Frank (University of Munich, Germany) ; Lyons, Arthur (Walter Reed Army Institute of Research) ; Joannidis, Michael (Medical University of Innsbruck, Innsbruck, Austria) ; Burgmann, Heinz (Medical University of Vienna) ; Welte, Tobias (Hannover Medical School, Hannover, Germany) ; Klingler, Anton (Assign Data Management and Biostatistics GmbH, Innsbruck, Austria) ; Hochreiter, Romana (Valneva Austria GmbH, Campus Vienna Biocenter 3, Vienna, Austria) ; Westritschnig, Kerstin (Valneva Austria GmbH, Campus Vienna Biocenter 3, Vienna, Austria) ; Universitat Autònoma de Barcelona
Currently, no vaccine against Pseudomonas is available. IC43 is a new, recombinant, protein (OprF/I)-based vaccine against the opportunistic pathogen, Pseudomonas aeruginosa, a major cause of serious hospital-acquired infections. [...]
2017 - 10.1186/s13054-017-1601-9
Critical Care, Vol. 21 (february 2017)  

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