Depósito Digital de Documentos de la UAB Encontrados 2 registros  La búsqueda tardó 0.01 segundos. 
1.
6 p, 1.1 MB A role for the spindle assembly checkpoint in the DNA damage response / Palou, Roger (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Palou, Gloria (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Garcia Quintana, David (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Spontaneous DNA damage poses a continuous threat to genomic integrity. If unchecked, genotoxic insults result in genomic instability, a hallmark of cancer cells. In eukaryotic cells a DNA Damage Response (DDR) detects and responds to genotoxic stress, acting as an anti-cancer barrier in humans. [...]
2016 - 10.1007/s00294-016-0634-y
Current Genetics, Vol. 63, Num. 2 (August 2016) , p. 275-280  
2.
26 p, 343.4 KB Fanconi anemia : A model disease for studies on human genetics and advanced therapeutics. / Bogliolo, Massimo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Fanconi anemia (FA) is characterized by bone marrow failure, malformations, and chromosome fragility. We review the recent discovery of FA genes and efforts to develop genetic therapies for FA in the last five years. [...]
2015 - 10.1016/j.gde.2015.07.002
Current opinion in genetics and development, Vol. 33 (Agost 2015) , p. 32-40  

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